Baqsimi® Nasal Glucagon Powder for Severe Hypoglycemia

What Baqsimi® Is and How It Works

Baqsimi Nasal Powder is a needle-free glucagon product from Eli Lilly used to treat severe hypoglycemia in people with diabetes ages 4 and older. It delivers a fixed 3 mg dose in one device. Patients and caregivers value its simplicity, fast action, and portability, especially when paying out of pocket or seeking Baqsimi without insurance pricing. YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba; prescriptions are reviewed by licensed pharmacists before dispensing.

Glucagon is a natural hormone that raises blood sugar. Baqsimi glucagon nasal powder binds receptors in the liver to trigger glycogen breakdown and gluconeogenesis, which increase circulating glucose. The device does not require inhalation. Pressing the plunger releases the powder into a nostril, where it is absorbed through the nasal mucosa.

Indication: emergency treatment of severe hypoglycemia when the patient cannot safely take oral carbohydrates. This includes episodes linked to insulin or sulfonylureas. Baqsimi nasal glucagon provides a single, ready-to-use option in home, school, work, or travel settings.

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Dosage and Usage

• Standard dose: one 3 mg device for adults and children 4 years and older. The Baqsimi dose is the same for all eligible ages.
• Each device is single-use. Keep a spare on hand when possible.
• Do not remove the device from its shrink-wrapped tube until needed. Do not test spray or prime.
• Initiation: lay the patient on their side if unconscious or at risk of vomiting.
• Administration steps (caregiver): remove the device from the tube, insert the tip gently into one nostril, and push the plunger all the way until the green line disappears.
• Breathing is not required during dosing. The device works without inhalation.
• Call for emergency assistance if the patient is unconscious or not improving.
• When the patient becomes responsive, give a fast-acting carbohydrate, then a snack or meal as directed by their care plan.
• If there is no response after 15 minutes, a second dose may be given using a new device.
• Missed dose: not applicable. Baqsimi one 3 mg dose powder is for emergency use, not routine dosing.
• Training: teach family, friends, teachers, and coworkers Baqsimi administration ahead of time. Review the patient’s action plan regularly.

• Store your devices at 20–25 °C (68–77 °F); short excursions 15–30 °C (59–86 °F) are usually acceptable.
• Keep Baqsimi in its shrink-wrapped tube to protect from moisture. Do not open until needed.
• Do not refrigerate or freeze. Avoid high heat (for example, a hot car) and direct sunlight.
• Check the expiration date. Replace expired devices before travel or events.
• For flights, keep your Baqsimi in carry-on baggage with your diabetes supplies.
• Consider packing a backup device for trips or long days away from home.

Benefits and Savings

Baqsimi Nasal Powder offers needle-free dosing, a fixed glucagon nasal powder 3 mg dose, and simple steps that trained caregivers can follow quickly. It avoids reconstitution, which can save time during urgent situations. Room-temperature storage supports everyday carry at work, school, or while traveling.

Clinical studies show most patients experience a meaningful rise in blood glucose within 15 minutes. The device is compact, discreet, and suitable for adults and children 4 years and older. Many caregivers prefer a nasal option versus injectable kits.

You can often save 60–80% compared with typical US prices. This helps when reviewing the Baqsimi price, the Baqsimi cost for families, or the Baqsimi cash price for those buying Baqsimi without insurance.

Looking for extra value? See our baqsimi nasal powder coupon page for current offers.

Side Effects and Safety

• Common: nausea, vomiting, headache, dizziness.
• Nasal/throat: nasal irritation or discomfort, runny nose, sneezing, watery eyes, cough, throat irritation.
• Cardiovascular: temporary increases in blood pressure or heart rate may occur.
• Other: fatigue, conjunctival irritation, or injection-like symptoms have been reported.

Serious risks are uncommon but include hypersensitivity reactions and lack of response in certain conditions. Do not use in people with pheochromocytoma due to risk of catecholamine release, or insulinoma due to potential recurrent hypoglycemia. Effect may be reduced in prolonged fasting, chronic hypoglycemia, adrenal insufficiency, or malnutrition. Drug interactions can occur with beta-blockers (greater heart rate/BP changes), indomethacin (reduced response), and warfarin (increased bleeding tendency). Severe hypoglycemia often occurs in people using insulin or sulfonylureas; Baqsimi treats episodes but does not replace ongoing glucose monitoring and medical care.

Onset Time

In most patients, a rise in blood sugar begins within 10–15 minutes after dosing, with clinical response commonly seen by 15 minutes. Full recovery varies based on the severity of hypoglycemia, hepatic glycogen stores, and concurrent medications. If there is no meaningful improvement after 15 minutes, a second device may be used.

Compare With Alternatives

Traditional glucagon emergency kits contain powder and diluent that must be mixed before injection. While effective, reconstitution takes time in urgent situations. Some households still prefer an injectable option; see the Glucagon Injection Kit With Diluent for comparison.

Ready-to-use injectable pens, such as prefilled glucagon products, also treat severe hypoglycemia with no mixing. These pens use subcutaneous injection instead of nasal delivery and may suit those comfortable with needles or who need specific device features.

If you or your caregiver are learning about treatment options for recurrent severe lows, explore our condition page on Severe Hypoglycemia Low Blood Sugar to see related therapies and supplies.

Combination Therapy

• Diabetes regimens often include basal and bolus insulin, or oral agents such as metformin or sulfonylureas. Baqsimi is for emergency use only.
• Prescribers may adjust insulin or sulfonylurea doses when hypoglycemia is frequent to reduce risk.
• Keep fast-acting carbohydrates available even when carrying Baqsimi nasal powder.
• Ensure caregivers know the action plan: dose Baqsimi, call for help when needed, and give oral carbs once the patient is awake.

Patient Suitability and Cost-Saving Tips

Suitable candidates include people with type 1 diabetes and insulin-treated type 2 diabetes who are at risk for severe hypoglycemia, and their trained caregivers. Households with children 4 years and older may benefit from a needle-free option. The fixed dose simplifies caregiver training and can help in school or sports settings.

Do not use Baqsimi in people with pheochromocytoma or insulinoma. Use caution in those with prolonged fasting, adrenal insufficiency, or malnutrition where hepatic glycogen may be depleted. Patients with nasal congestion or recent nasal surgery can still respond, though local irritation may be more noticeable.

For budgeting, consider ordering more than one device at a time when appropriate. Multi-month supplies or bulk promotions can lower the per-month cost. You can set gentle reorder reminders in your account so you do not run short. These steps can help manage Baqsimi savings and the Baqsimi out of pocket cost, including when buying without insurance.

Authoritative Sources

Eli Lilly Baqsimi prescribing information (United States)

Health Canada Drug Product Database: Baqsimi

FDA label and Medication Guide for Baqsimi

Order Baqsimi® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express shipping.

This content is educational and does not replace professional medical advice. Always follow your prescriber’s directions and the patient information that comes with your medication.