How is Bavencio given and how often are infusions?

Bavencio is an intravenous infusion prepared and administered by healthcare professionals. A fixed dose is often used, commonly every two weeks. The first few infusions may be slower with premedication to reduce infusion reactions. Your oncologist will set the exact schedule based on your diagnosis, response, and tolerability.

What are common Bavencio side effects and serious risks?

Common effects include fatigue, fever, diarrhea, nausea, decreased appetite, cough, and skin rash or itching. Serious immune-related reactions can involve lungs, colon, liver, endocrine glands, kidneys, or skin. Infusion reactions can also occur. Report new or worsening symptoms promptly to your care team for evaluation and management.

Is there a generic for Bavencio or a lower-cost equivalent?

There is no approved generic avelumab at this time. Other checkpoint inhibitors are not direct generics and differ by target, indication, and data. YouDrugstore offers Canadian pricing, so the Bavencio price can be lower than typical US retail. Our team can explain packaging and shipping options for your prescription.

How should Bavencio be stored and shipped?

Bavencio vials should be kept refrigerated at 2–8°C in the original carton and protected from light. Do not freeze or shake. Shipments are packed with cold-chain materials. Bring sealed vials to your infusion center for preparation. Do not attempt to open or self-administer the medication at home.

Who may not be a good candidate for Bavencio?

Patients with active autoimmune disease, prior organ transplant, uncontrolled infections, or a history of severe immune-related reactions need careful evaluation. Pregnancy and breastfeeding require special consideration. The oncology team will review your history, labs, and prior treatments to decide if avelumab is appropriate.

Can I get Bavencio without insurance through your pharmacy?

Yes. Many patients pay cash when insurance will not cover therapy. YouDrugstore provides Canadian pricing that can reduce total cost. You can compare the Bavencio price, review bulk options if offered, and plan shipments with customer-service support to help manage expenses alongside clinic infusion fees.

How do I order and what documents are required?

Place your order online or by phone. A valid prescription from your oncologist is required. Our pharmacists review every order before dispensing. Customer-service chat is available during posted office hours to help with account setup, document uploads, and shipping arrangements for delivery to you or your clinic.

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Bavencio

Bavencio® (avelumab) infusion for MCC, urothelial cancer, and RCC

Cancer

Please note: a valid prescription is required for all prescription medication.

Save 15% on Eligible Cancer Meds. Use Coupon Code: SAVE15

Price:

$1,650.99

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What Bavencio® Is and How It Works

Bavencio® (avelumab) is an immune checkpoint inhibitor. It targets PD-L1 to help the immune system detect and attack cancer cells. It is approved for metastatic Merkel cell carcinoma, maintenance treatment of locally advanced or metastatic urothelial carcinoma after platinum chemotherapy, and in combination with axitinib for first-line advanced renal cell carcinoma. It is supplied as an intravenous infusion given by trained professionals. Many people compare Bavencio price and plan for Bavencio cost without insurance when arranging treatment through a pharmacy service.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba. Prescriptions are reviewed by licensed pharmacists before dispensing, and you can order brand and generic medicines at Canadian prices. Our team also carries OTC health products and offers friendly customer-service chat during posted office hours.

To keep costs manageable, we work with licensed, vetted partner pharmacies internationally to supply authentic brand medicines, with a broad selection and competitive pricing.

Dosage and Usage

Bavencio® is administered by infusion in a clinic or infusion center. Dosing is set by the treating team and depends on the indication and response. A fixed-dose schedule is commonly used.

Typical adult dosing uses 800 mg by IV infusion over about 60 minutes every 2 weeks.
When used with axitinib for renal cell carcinoma, axitinib tablets are taken separately as directed by the prescriber.
Premedication may be used to reduce infusion reactions, based on local protocols.
Duration of therapy depends on response and tolerability. Treatment may continue until disease progression or unacceptable toxicity.
If an infusion is missed, the care team will plan the next visit as soon as practical and adjust the schedule.

Storage and travel tips for your shipment:

Keep vials refrigerated at 2–8°C (36–46°F). Do not freeze or shake.
Store in the original carton to protect from light.
If you travel to an infusion center, use an insulated bag and cold packs. Keep your shipment upright and secure.
Do not open vials or attempt to prepare or self-administer. Bring the sealed product to the clinic for preparation.
Keep out of reach of children and pets. Follow any return or disposal instructions from your clinic.

Benefits and Savings

Clinical trials show durable responses in metastatic Merkel cell carcinoma. As maintenance therapy for urothelial carcinoma, Bavencio® improved overall survival after initial platinum chemotherapy. In advanced renal cell carcinoma, the combination of avelumab plus axitinib improved progression-free survival compared with sunitinib in a pivotal study.

Ordering through YouDrugstore offers the convenience of Canadian pricing and careful pharmacist review. Many patients paying without insurance look for ways to lower ongoing costs. Savings of 60–80% vs typical US retail prices are common for many brand medicines, and oncology products often show meaningful differences.

Side Effects and Safety

Immune checkpoint inhibitors can cause immune-related side effects. These may involve the lungs, colon, liver, endocrine glands, kidneys, skin, or other organs. Monitoring and prompt reporting of symptoms to the care team are essential.

Common side effects: fatigue, fever, nausea, diarrhea, decreased appetite, constipation, cough, headache, muscle or joint pain, rash, and itching.
Lab changes and endocrine issues: thyroid disorders (hypo- or hyperthyroidism), adrenal insufficiency, or diabetes may occur.
Immune-related events: pneumonitis, colitis, hepatitis, nephritis, pancreatitis, myocarditis, and severe skin reactions can occur.
Infusion-related reactions: chills, shortness of breath, flushing, back pain, or low blood pressure during or after infusion.
Serious risks: severe immune reactions, severe infections, and rare fatal events have been reported.

Patients with autoimmune disease, prior organ transplant, active infection, or pregnancy require careful risk assessment. Breastfeeding is usually not recommended during treatment and for a period after the last dose. The treating oncologist will decide on dose holds or discontinuation if serious toxicity occurs.

Onset Time

Immune responses develop over time. Some patients notice improvement within several weeks, but the best response may take a few months. Stable disease can precede tumor shrinkage. Clinicians monitor progress with symptoms, labs, and scheduled imaging. Durable responses have been observed in responding patients.

Compare With Alternatives

For similar settings, other checkpoint inhibitors may be considered. Pembrolizumab (a PD-1 inhibitor) and atezolizumab (a PD-L1 inhibitor) are examples used in select urothelial and other cancers. Choice depends on tumor type, prior therapy, biomarkers, and tolerance.

Other oncology treatments address different pathways and diagnoses. For example, Zytiga® (abiraterone acetate) is used in prostate cancer with prednisone. In certain lung cancers with ALK rearrangements, Xalkori® (crizotinib) is a targeted option. These are not direct substitutes for Bavencio® but illustrate the range of therapies available through our pharmacy.

Your oncology team weighs benefits and risks of each therapy. Availability, dosing schedules, and insurance or cash costs also affect planning.

Combination Therapy

Bavencio® is given alone for Merkel cell carcinoma and urothelial carcinoma maintenance. It is combined with axitinib tablets for first-line advanced renal cell carcinoma. Supportive care may include premedication to reduce infusion reactions, as directed by the infusion center. Physicians may add or hold therapies based on response and side effects.

Patient Suitability and Cost-Saving Tips

Bavencio® may suit adults with confirmed indications who can attend regular infusions and routine monitoring. Caution is needed in patients with active autoimmune disease, prior severe immune-related events, organ transplants, uncontrolled infections, or during pregnancy and breastfeeding. The oncology team decides on eligibility and timing.

Ways to manage out-of-pocket costs include planning multi-month shipments when appropriate, setting up reorder reminders, and comparing pack sizes if offered. If you are looking for a Bavencio coupon, see current offers and bulk options on our Promotions page. Patients paying cash may also compare clinic preparation fees and infusion center charges. This can help lower total therapy costs alongside the medication price.

Explore more oncology options within our Cancer category. For background reading, see our overview article, Bavencio Avelumab A Closer Look At This Immunotherapy, which explains mechanism and clinical use in plain language.

Authoritative Sources

For full product details, refer to the FDA Prescribing Information for Bavencio (avelumab). Canadian information can be found in the Health Canada Drug Product Database entry for Bavencio. The manufacturer provides resources on the Bavencio Patient Website.

Have questions about ordering or shipping? YouDrugstore supports your care team with pharmacy review and reliable delivery. We offer prompt, express, cold-chain shipping to keep temperature-sensitive products within range.

This content is for general information only and does not replace medical advice. Always follow the directions of your prescriber and infusion center, and read the supplied product information before starting therapy.

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View All FAQs

How is Bavencio given and how often are infusions?
Bavencio is an intravenous infusion prepared and administered by healthcare professionals. A fixed dose is often used, commonly every two weeks. The first few infusions may be slower with premedication to reduce infusion reactions. Your oncologist will set the exact schedule based on your diagnosis, response, and tolerability.
What are common Bavencio side effects and serious risks?
Common effects include fatigue, fever, diarrhea, nausea, decreased appetite, cough, and skin rash or itching. Serious immune-related reactions can involve lungs, colon, liver, endocrine glands, kidneys, or skin. Infusion reactions can also occur. Report new or worsening symptoms promptly to your care team for evaluation and management.
Is there a generic for Bavencio or a lower-cost equivalent?
There is no approved generic avelumab at this time. Other checkpoint inhibitors are not direct generics and differ by target, indication, and data. YouDrugstore offers Canadian pricing, so the Bavencio price can be lower than typical US retail. Our team can explain packaging and shipping options for your prescription.
How should Bavencio be stored and shipped?
Bavencio vials should be kept refrigerated at 2–8°C in the original carton and protected from light. Do not freeze or shake. Shipments are packed with cold-chain materials. Bring sealed vials to your infusion center for preparation. Do not attempt to open or self-administer the medication at home.
Who may not be a good candidate for Bavencio?
Patients with active autoimmune disease, prior organ transplant, uncontrolled infections, or a history of severe immune-related reactions need careful evaluation. Pregnancy and breastfeeding require special consideration. The oncology team will review your history, labs, and prior treatments to decide if avelumab is appropriate.
Can I get Bavencio without insurance through your pharmacy?
Yes. Many patients pay cash when insurance will not cover therapy. YouDrugstore provides Canadian pricing that can reduce total cost. You can compare the Bavencio price, review bulk options if offered, and plan shipments with customer-service support to help manage expenses alongside clinic infusion fees.
How do I order and what documents are required?
Place your order online or by phone. A valid prescription from your oncologist is required. Our pharmacists review every order before dispensing. Customer-service chat is available during posted office hours to help with account setup, document uploads, and shipping arrangements for delivery to you or your clinic.