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Combivent Respimat® Inhaler for COPD
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This combination inhaler pairs ipratropium and albuterol to help manage COPD symptoms. You will find how it works, how to use it, and ways to access US delivery from Canada, even if you are paying without insurance. Use this guide to understand key safety points before you order or travel with your medicine.
What Combivent Is and How It Works
Combivent Respimat® inhalation spray delivers two short-acting bronchodilators in a soft mist. Ipratropium is an anticholinergic that relaxes airway smooth muscle by blocking muscarinic receptors. Albuterol (salbutamol) is a beta2-agonist that stimulates receptors to open the airways. The combination can reduce bronchospasm in adults with chronic obstructive pulmonary disease who need more than one bronchodilator.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This therapy is not intended to treat acute, life-threatening episodes. Keep your rescue reliever on hand as directed by your prescriber. Read the patient leaflet for device setup, priming, and cleaning steps before first use.
Who It’s For
This medicine is prescribed for adults with COPD, including chronic bronchitis and emphysema, who require two bronchodilators. It may help when symptoms persist despite a single agent. It is not approved for asthma treatment. Children and adolescents are generally not candidates.
Avoid use if you have had a serious allergy to ipratropium, atropine derivatives, or albuterol. Use caution if you have narrow-angle glaucoma, urinary retention, enlarged prostate, certain heart rhythm problems, or uncontrolled hypertension. Discuss your history of seizures, hyperthyroidism, or diabetes with your clinician. Tell your healthcare professional about all inhalers and pills you use for breathing.
Dosage and Usage
Typical labeled dosing is one inhalation four times daily. Do not exceed six inhalations in 24 hours unless your prescriber advises otherwise. This ipratropium albuterol inhaler uses the Respimat device, which creates a slow-moving mist to aid delivery.
Device basics:
- First use: assemble the cartridge into the device per the leaflet, then prime until you see a visible mist and repeat as instructed.
- Daily use: turn the base until it clicks, open the cap, breathe out, seal lips around the mouthpiece, and inhale slowly and deeply while pressing the dose button.
- Breath technique: aim for a long, steady breath in; hold your breath for up to 10 seconds, then exhale gently.
- Cleaning: wipe the mouthpiece, including the metal outlet, with a damp cloth at least weekly.
If the device has not been used for several days, a brief re-priming step may be needed. Follow the product leaflet for exact priming instructions. Do not spray into your eyes. If you experience eye pain or visual halos, seek medical care.
Strengths and Forms
The product is supplied as a soft-mist inhaler. A commonly dispensed presentation is Combivent Respimat 20/100 mcg per actuation (ipratropium bromide 20 mcg and albuterol base 100 mcg). Availability may vary by country and manufacturer packaging.
Each device includes labeled metered actuations with a dose indicator. Your pharmacist can help you match the labeled strength and pack size to your prescription.
Missed Dose and Timing
If you miss a scheduled inhalation, take it when you remember unless it is close to the next dose. Do not take two doses at once. Aim for evenly spaced times during waking hours. If you frequently forget doses, set reminders or pair dosing with daily routines like meals or tooth brushing.
Storage and Travel Basics
Store the inhaler at room temperature and keep the cap closed when not in use. Avoid heat, open flame, and direct sunlight. Do not freeze the cartridge. Keep out of reach of children. Do not puncture the device or expose it to high temperatures.
For travel, carry the inhaler and your prescription label in your hand luggage. Keep a copy of your prescription or a medication list for security checks. Clean the mouthpiece before trips and pack a protective case to prevent accidental actuation. If you are close to the end of the dose counter, arrange a refill before leaving.
Some packs contain Combivent Respimat 120 inhalations with an indicator that turns red near the end. Do not try to extract extra doses once the counter shows zero.
Benefits
This treatment combines two proven bronchodilators in one device, which can simplify daily therapy. The soft-mist inhaler delivers a slow plume that may be easier to coordinate with inhalation than a pressurized inhaler. Many patients appreciate the dose indicator that helps prevent running out unexpectedly. Regular use may reduce day-to-day breathlessness and support activities like walking or household tasks.
Side Effects and Safety
- Dry mouth
- Cough or throat irritation
- Headache or dizziness
- Shaky feeling or tremor
- Palpitations
- Nausea
Serious but less common risks include paradoxical bronchospasm, worsening narrow-angle glaucoma, urinary retention, or significant changes in heart rate or blood pressure. Stop use and seek medical attention if you develop rash, swelling, or breathing that suddenly gets worse after inhalation. If you have heart disease or arrhythmias, discuss risks and monitoring with your prescriber before starting.
Drug Interactions and Cautions
Tell your clinician about all medicines you take. Interactions may occur with beta-blockers, MAO inhibitors, tricyclic antidepressants, other anticholinergics, stimulant decongestants, or diuretics that can lower potassium. Using other short-acting bronchodilators at the same time can increase side effects. Alcohol and caffeine may worsen tremor or palpitations in some people. Do not change your regimen without guidance from a healthcare professional.
What to Expect Over Time
With consistent use, breathing may feel easier between doses. You should still carry a rapid reliever inhaler for sudden symptoms if prescribed. Track your inhalations with the device counter and a simple checklist or phone reminder. If symptoms remain troublesome, talk with your prescriber about your inhaler technique and overall COPD plan, including pulmonary rehabilitation, vaccines, and smoking cessation support when relevant.
Compare With Alternatives
Some adults benefit from a long-acting bronchodilator or a dual long-acting option. Your clinician may consider a once-daily anticholinergic such as Spiriva® Respimat Inhaler, or a LAMA/LABA combination like Anoro® Ellipta Inhaler. Choice depends on your symptoms, technique, and previous response. Review your options if you continue to need frequent rescue doses or have repeated exacerbations.
Pricing and Access
See today’s Combivent Respimat price and current availability on this page. This product Ships from Canada to US with pharmacy dispensing. Compare Canadian pricing to your local cash pay by checking the product detail. To view item-specific pricing, add your quantity and proceed to the cart for a full breakdown.
Looking for a coupon? Visit our Promotions page for current offers that may apply to respiratory medicines. You can also explore broader options in our Respiratory category and learn more about COPD care in Chronic Obstructive Pulmonary Disease Copd.
For education on lung health and COPD management, see Respiratory Care Week, Healthy Lung Month, Treatment And Medications, and What Is Asthma. These resources cover breathing tips, inhaler basics, and clinic follow-up planning.
Availability and Substitutions
If your prescribed pack is not available, your prescriber may recommend an alternative anticholinergic, a separate short-acting beta2-agonist, or a long-acting maintenance option. Substitution should only occur with prescriber approval, as inhaler devices and dosing differ. We do not promise restock dates; check back or consult your clinician for a therapeutic alternative that fits your plan.
Patient Suitability and Cost-Saving Tips
This combination may suit adults with persistent COPD symptoms who need both an anticholinergic and a short-acting beta2-agonist. It may not be appropriate if you have poorly controlled heart disease, untreated narrow-angle glaucoma, significant urinary retention, or a history of severe hypersensitivity to components. Always review your full medicine list with your healthcare professional.
Ways to save time and costs include requesting multi-month fills when appropriate, aligning refill dates with other therapies, and using refill reminders. If travel is planned, schedule a refill a week or two before departure. Review inhaler technique at each visit to get the most from every dose. Encrypted checkout protects your order details during payment.
Questions to Ask Your Clinician
- Is this the right combination inhaler for my COPD symptoms?
- How should I coordinate this with my rescue reliever and any long-acting inhaler?
- What signs suggest I should call the clinic about side effects?
- Which other medicines or supplements could interact with my inhalers?
- Can you check my inhaler technique to ensure full benefit?
- Would pulmonary rehabilitation or vaccinations help my long-term plan?
Authoritative Sources
| Source | Link |
|---|---|
| Manufacturer Product Site | combivent.com |
| FDA DailyMed | DailyMed Search |
| Health Canada DPD | Drug Product Database |
Ready to proceed? Add to cart and complete checkout for prompt US shipping from Canada with temperature-controlled handling when required. This page does not replace medical advice; always follow your prescriber and the official label.
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Can this inhaler replace my rescue reliever?
No. This combination is taken on a regular schedule to help reduce bronchospasm in COPD. You should keep your fast-acting rescue inhaler available for sudden breathing symptoms if prescribed. Ask your clinician how to use each inhaler, how many puffs to take, and when to seek urgent care. If symptoms worsen despite use, contact your healthcare professional promptly for guidance.
How do I prime and use the Respimat device correctly?
Before first use, insert the cartridge following the leaflet. Turn the base until it clicks, open the cap, and press the dose button while aiming away from your face until a mist is seen; repeat the priming steps as instructed. For each dose, breathe out, seal lips around the mouthpiece, inhale slowly and deeply while pressing the button, then hold your breath briefly. Clean the mouthpiece weekly. Re-prime if it has been unused for several days, per the label.
What side effects should I watch for?
Common effects include dry mouth, throat irritation, cough, tremor, headache, or palpitations. Serious reactions are uncommon but can include paradoxical bronchospasm, worsening narrow-angle glaucoma symptoms, urinary retention, or significant changes in heart rate or blood pressure. Seek medical attention for severe eye pain, swelling, rash, or breathing that suddenly worsens after a dose. Discuss your history and risk factors with your clinician before starting.
Is this suitable for asthma?
This combination is indicated for chronic obstructive pulmonary disease and is not approved for asthma. Some patients with asthma may use other maintenance therapies that include inhaled corticosteroids and long-acting bronchodilators. Your prescriber will choose a plan based on your diagnosis, triggers, and symptom pattern. Do not change or add inhalers without professional guidance.
What if I am using other inhalers or pills for COPD?
Share a complete medication list with your healthcare professional. Using other short-acting bronchodilators or anticholinergics at the same time may increase side effects. Beta-blockers, certain antidepressants, decongestants, and some diuretics can interact as well. Your clinician can help time doses and decide whether to continue, switch, or simplify therapy. Never stop maintenance medicines abruptly without advice.
How should I store the device and travel with it?
Keep the inhaler at room temperature, away from heat and direct sunlight, and do not freeze the cartridge. Close the cap when not in use. For travel, carry it in your hand luggage with your prescription label. Bring a copy of your prescription if possible. If the counter is near zero, arrange a refill before departure. Clean the mouthpiece before trips and keep a protective case to prevent accidental spraying.
What happens if I miss a dose?
Take the missed inhalation when you remember unless it is almost time for the next scheduled dose. Do not double up to make up for a missed dose. Try using reminders or pairing doses with daily routines to keep a steady schedule. If you frequently miss doses or feel your symptom control is not adequate, contact your clinician to review your approach and technique.


