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Diacomit

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Diacomit (stiripentol) is a prescription medicine used together with other antiepileptic drugs to treat severe seizures in children with Dravet syndrome, a rare and difficult-to-control form of epilepsy.

Benefits

  • Helps reduce the frequency and severity of seizures in children with Dravet syndrome
  • Used in combination with clobazam and valproate for better seizure control
  • May help improve daily functioning and reduce emergency hospital visits
  • Taken orally as capsules or powder for suspension (for children who can’t swallow pills)

Dosage

  • Dose is based on body weight and given two or three times a day
  • Usually taken with food to help reduce stomach upset
  • The doctor may adjust the dose gradually based on response and side effects
  • Always follow the treatment plan exactly as prescribed

Warnings and Precautions

  • Can cause drowsiness or sleepiness, especially when used with other seizure medicines
  • May interact with other medications — inform your doctor of all medicines being used
  • Requires regular monitoring of liver function and blood cell counts
  • Tell your doctor if your child has liver problems or is not gaining weight normally
  • Not recommended during pregnancy or breastfeeding unless clearly needed

How to Use

  • Take at the same times every day, with meals
  • Do not skip doses — consistency is important for seizure control
  • If you miss a dose, take it as soon as possible unless it’s almost time for the next one
  • Do not stop using Diacomit suddenly — this may cause seizures to worsen
  • Powder form should be mixed with water and given right after preparation

Storage

  • Store at room temperature (15–30°C)
  • Keep away from moisture, heat, and direct light
  • Keep out of reach of children
  • Do not use after the expiry date on the packaging

Side Effects

  • Common: drowsiness, loss of appetite, weight loss, nausea, trouble sleeping
  • Other possible: irritability, unsteadiness, low white blood cell count
  • Serious (seek help): persistent vomiting, signs of infection (fever, sore throat), unusual tiredness, yellowing of the skin or eyes (liver issues)

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