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Diacomit® Capsules for Dravet Syndrome
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Diacomit is a prescription anti-seizure medicine used with clobazam to help manage seizures in Dravet syndrome. This page explains how it works, who it suits, and safe use basics. US delivery from Canada is available, and you can review Diacomit® cost without insurance before you decide.
What Diacomit Is and How It Works
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This medicine contains stiripentol, an anticonvulsant approved as add-on therapy to clobazam for Dravet syndrome. It may enhance GABAergic activity and inhibit certain liver enzymes, which increases levels of clobazam’s active metabolite. That interaction can help reduce seizure frequency when used with your child’s established regimen. Learn more about the condition in our overview of Dravet Syndrome.
It should be used exactly as prescribed, with regular follow-up. Your prescriber may monitor growth, appetite, and lab work to support long-term safety.
Who It’s For
This treatment is indicated as adjunctive therapy with clobazam for patients with Dravet syndrome, typically starting at 2 years of age and older. It is not approved as monotherapy. People with significant liver or kidney impairment, or with known hypersensitivity to stiripentol or excipients, should avoid it. Discuss current medicines, supplements, and any metabolic or eating concerns before starting.
Dosage and Usage
Dosing is weight-based and individualized. Prescribers usually start at a lower amount and increase to a target daily dose over several days. It is given two or three times daily with food. Capsules should be swallowed whole with water. Do not open, crush, or chew capsules. Take doses at the same times each day to support consistent blood levels.
If you use the powder for oral suspension, mix a packet with water or a soft food right before giving the dose. Administer the full mixture promptly and do not store the prepared mixture for later. Avoid grapefruit or grapefruit juice, which can affect metabolism of the therapy and other medicines.
Your prescriber may adjust clobazam or other anti-seizure medicines after starting this therapy. Follow the official label and clinic guidance if changes are considered.
Strengths and Forms
Availability may vary. Commonly supplied presentations include:
- Capsules: 250 mg and 500 mg
- Powder for oral suspension packets: 250 mg and 500 mg per packet
Check the Diacomit 250 mg price on this page when selecting the form and quantity. Your clinician will choose a strength that matches the weight-based plan.
Missed Dose and Timing
If a dose is missed, give it as soon as you remember unless it is near the next scheduled time. If it is close to the next dose, skip the missed dose and return to the regular schedule. Do not double up doses. If your child vomits soon after a dose, follow your prescriber’s guidance on whether to re-dose.
Storage and Travel Basics
Store capsules and packets at room temperature in a dry place, away from excess heat and light. Keep in the original, child-resistant packaging. Do not use packets after the printed expiration date. After mixing a packet, give it right away and discard any leftover mixture. When traveling, keep medicines in your carry-on, with the pharmacy label and prescription details. Bring a copy of your prescription and a dosing schedule to simplify airport screening and international trips.
Keep all medicines out of sight and reach of children and pets.
Benefits
When added to clobazam, this therapy may help reduce seizure frequency in Dravet syndrome. It can be given as capsules or a powder, which may help with administration in younger patients. Using it consistently, with regular follow-up, can support a stable routine and coordinated care with your neurology team.
Side Effects and Safety
- Decreased appetite and weight loss
- Sleepiness or fatigue
- Agitation or irritability
- Ataxia or unsteady movements
- Nausea, vomiting, or abdominal discomfort
- Insomnia or sleep disturbance
- Drooling or hypersalivation
Serious but less common risks include low white blood cells or platelets, liver enzyme elevations, and increased sedation, especially with clobazam or other CNS depressants. All antiepileptic drugs carry a warning for suicidal thoughts or behavior; contact a healthcare professional if mood or behavior changes occur. Do not stop antiepileptics suddenly, as this can increase seizure risk.
Drug Interactions and Cautions
Stiripentol inhibits CYP1A2, CYP2C19, and CYP3A4, which can raise levels of medicines metabolized by these enzymes. Notable interactions include clobazam and valproate. Use caution with theophylline, caffeine, some antidepressants, certain benzodiazepines, and other drugs with narrow therapeutic windows. Alcohol and other sedating agents can add to drowsiness. Avoid grapefruit products. People with moderate to severe liver or kidney impairment may require special consideration or avoidance. Always tell your prescriber about every prescription, over-the-counter product, and supplement.
What to Expect Over Time
Seizure improvement is usually assessed over weeks in coordination with your neurology team. The aim is a meaningful reduction in seizure frequency and severity while balancing tolerability. Keep a seizure diary, track appetite and sleep, and attend scheduled visits. Your prescriber may order blood tests to monitor safety, particularly early in treatment or after dose adjustments.
Planning for ongoing therapy includes budgeting for refills and choosing suitable forms. If you prefer packets, you can review Stiripentol powder for suspension price before deciding. For background reading on living with seizures, see our article Epilepsy When The Brain.
Compare With Alternatives
Other antiseizure options may be considered by your prescriber based on age, seizure type, and prior response. Two options we carry include Banzel and Levetiracetam. Use our tools to Compare Diacomit prices across forms, then discuss choices with your clinician. Selection depends on medical history, other medicines, and monitoring needs.
Pricing and Access
We display clear Canadian pricing for each form and pack size. You can Buy stiripentol capsules here after your prescription is received. For questions on savings, check our Promotions. Ships from Canada to US with reliable delivery, and checkout is encrypted. Prescription required and verified before fulfilment.
Availability and Substitutions
Supply can vary by strength and form. If an item is temporarily unavailable, your prescriber may recommend an appropriate alternative or a different pack size. Stiripentol price may differ between capsules and packets due to packaging and supply factors. We do not list restock dates; your care team can advise on timing and substitution decisions.
Patient Suitability and Cost-Saving Tips
This therapy may suit patients with confirmed Dravet syndrome who are already taking clobazam and need additional control. It may not be appropriate for people with severe hepatic or renal impairment or those on interacting medicines with narrow safety margins. To save on refills, consider multi-month quantities when clinically appropriate, set refill reminders, and coordinate all prescriptions through one pharmacy to streamline reviews. If you are tracking Diacomit prescription cost, compare forms and quantities with your prescriber’s plan so you order what matches the dosing schedule.
Explore related topics and products in Neurology and Epilepsy to stay informed.
Questions to Ask Your Clinician
- Role with clobazam: How will this add-on fit my current regimen?
- Monitoring plan: What labs or growth checks are needed?
- Side effects: What signs mean I should call the office?
- Food and timing: Are there meals or drinks I should avoid?
- Form choice: Should I use capsules or packets for my situation?
- Travel plan: How should I pack and carry doses on trips?
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How does stiripentol work with clobazam?
Stiripentol is an anticonvulsant used as add-on therapy in Dravet syndrome. It may increase GABAergic activity and inhibits liver enzymes that metabolize some drugs, including clobazam. By inhibiting CYP2C19 and CYP3A4, it can raise levels of clobazam’s active metabolite, which may enhance antiseizure effects. Because of this interaction, clinicians often monitor for sedation and adjust related therapies when needed. Always follow your prescriber’s plan and the official labeling for co-administration details.
Can adults take this medicine?
Yes, adults with Dravet syndrome who still require add-on therapy to clobazam may be candidates. Dosing is individualized and based on weight and tolerability. People with significant liver or kidney impairment, or those taking interacting medicines with narrow safety margins, may not be suitable. Your healthcare professional will consider seizure history, concurrent therapies, and monitoring needs before deciding whether stiripentol is appropriate for you.
What foods or drinks should I avoid?
Take doses with food. Avoid grapefruit and grapefruit juice, which can affect the metabolism of stiripentol and other medicines. Limit alcohol due to additive sedation and dizziness. If a packet is used, prepare the mixture right before administration and give it promptly. Maintain consistent mealtimes to help with routine dosing, and discuss any dietary supplements or high-caffeine products with your prescriber.
What lab monitoring is recommended?
Clinicians may order baseline and periodic labs, especially early in treatment or after changes. Common checks include complete blood count and liver enzymes. Growth, weight, and appetite are also monitored in children. Additional assessments can be done based on concurrent therapies, such as clobazam or valproate. Monitoring plans vary; follow your clinician’s schedule and report any unusual tiredness, bruising, infections, or yellowing of the skin or eyes.
How is the powder taken?
The powder for oral suspension comes in single-use packets. Mix the contents with water or a soft food immediately before administration. Give the full mixture right away and do not store leftovers. Use the exact amount directed by your prescriber. Avoid grapefruit products. If swallowing is difficult, ask your clinician or pharmacist for administration tips that fit your child’s routine.
What if my child vomits the dose?
If vomiting happens soon after a dose, contact your prescriber or pharmacist for guidance. Do not automatically give an extra dose without professional advice. Keep a note of when the dose was taken and the time vomiting occurred, as this helps clinicians advise next steps. For recurrent episodes, discuss administration timing with meals and potential adjustments to improve tolerability.
Is generic stiripentol available?
Availability of generic products may vary by country and over time. Your pharmacist can advise whether a generic stiripentol product is available for your prescription and whether substitution is appropriate. If a specific brand is prescribed, follow your prescriber’s instructions. Pricing and supply can differ by form and strength, so review options with your healthcare professional and pharmacy.

