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Eylea® Injection for Wet Age-Related Macular Degeneration
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What Eylea® Is and How It Works
Eylea is a prescription intravitreal injection used for several retinal conditions. It helps reduce abnormal blood vessel growth and leakage in the eye. This page explains how treatment works, who it may suit, and how ordering with US delivery from Canada fits your care, including options without insurance. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
Eylea® medicine contains aflibercept, a vascular endothelial growth factor (VEGF) inhibitor. By blocking VEGF and placental growth factor, it helps stabilize vision in wet age-related macular degeneration and diabetic eye disease. Specialists also use this therapy for macular edema from retinal vein occlusion and other approved indications. Learn about these conditions in our resources for Wet Age Related Macular Degeneration, Diabetic Macular Edema, and Retinal Vein Occlusion.
Who It’s For
This treatment is approved for adults with neovascular (wet) age-related macular degeneration. It is also used for diabetic macular edema and complications from retinal vein occlusion. Clinicians may prescribe it for myopic choroidal neovascularization where labeled. People with active eye or periocular infection, or active intraocular inflammation, should not receive injections until resolved. Do not use if you have known hypersensitivity to aflibercept or any component.
Tell your healthcare professional about recent eye surgery, glaucoma, or a history of stroke. Discuss pregnancy and breastfeeding. Safety in children has not been established. For broader reading on condition pathways, see our category for Age Related Macular Degeneration and the Ophthalmology category.
Dosage and Usage
This medicine is given by an eye specialist as an intravitreal injection in a clinical setting. Typical schedules follow the product label for each condition. For wet AMD, treatment often starts with a series of monthly doses before moving to longer intervals as directed by your specialist. For diabetic macular edema, initial monthly injections may be followed by less frequent visits if vision and anatomy are stable. For macular edema due to retinal vein occlusion, dose timing is guided by your response and clinical findings.
The Eylea injection dose and schedule are set by your prescriber. Do not self-inject. On procedure days, follow clinic guidance about eye drops, makeup, and contact lenses. Arrange a companion if your vision may be blurry afterward. If you receive other eye medicines, your clinician will space them appropriately. When uncertain about specific intervals, follow the official label and your specialist’s plan.
Strengths and Forms
Availability may vary by market and supply. Common presentations include a single-dose vial or prefilled syringe for clinic use. Many patients receive an Eylea 2 mg vial in standard care, depending on the prescriber’s protocol and inventory. Higher-strength options exist in some regions and may allow longer intervals between visits, subject to the label and clinical judgment. Your clinic determines which presentation and device are used.
Missed Dose and Timing
If you miss an appointment, contact your eye clinic promptly to reschedule. Timing is important for maintaining vision benefits, but one delay does not define your long-term plan. Your specialist will adjust the next visit based on your exam and imaging. Do not double up or compress appointments without guidance.
Storage and Travel Basics
Clinics store and prepare the injection; you normally do not handle this product at home. If your prescriber asks you to bring a dose to an appointment, keep it in the original packaging and follow the pharmacy’s storage instructions. Protect from freezing and excessive heat. Keep medicines out of reach of children and pets. If you must travel with a dose for clinic use, use appropriate insulation and ask the clinic about timing so you can maintain proper handling.
For your own travel planning, bring your prescription details, your clinic contact information, and copies of recent visit notes if you are seeing a new specialist. Allow extra time for airport security if carrying medical supplies. If you have questions about proper handling, ask your pharmacist before transport.
Benefits
Anti-VEGF therapy may help maintain or improve central vision in qualifying conditions. Many patients value the possibility of longer intervals after initial loading, which can reduce visit burden. Clinic-based administration ensures trained staff handle setup and monitoring. The treatment can be combined with imaging-guided follow-up to tailor the interval over time.
Side Effects and Safety
- Common effects: eye discomfort, mild pain, increased tearing
- Transient floaters or small visual spots
- Subconjunctival hemorrhage (small red area on the white of the eye)
- Temporary light sensitivity or irritation
Serious but less common risks include endophthalmitis, retinal detachment, intraocular inflammation, and increased intraocular pressure after injection. Use urgent care if you notice severe eye pain, worsening redness, sudden vision loss, or many new floaters shortly after a procedure. When given with insulin or sulfonylureas, anti-VEGF does not typically cause hypoglycemia, but people with diabetes should follow standard glucose monitoring and clinic advice.
Drug Interactions and Cautions
Systemic interactions are unlikely given local ocular dosing, but your prescriber should review all medicines and supplements. Tell your clinician about anti-thrombotic therapy, recent cardiovascular events, or other biologics. Do not use during active eye infection or significant inflammation. Report any history of stroke or transient ischemic attack, and discuss risk management for your situation.
What to Expect Over Time
After injection, vision may be blurry for a short period. Most clinics provide protective instructions for the hours after treatment. Your plan may start with more frequent visits, then spacing can increase if your condition stabilizes. Consistent follow-up and imaging support long-term outcomes. Keep a calendar and set reminders so you do not miss appointments. If changes in vision occur between visits, contact your clinic rather than waiting for the next scheduled exam.
If you live with diabetes, coordinated care with your primary team can support eye health. For broader awareness content, you can read our article Diabetes Month 2025.
Compare With Alternatives
Other anti-VEGF options may be appropriate based on your diagnosis and response. Ranibizumab is a well-studied choice and is available as a vial or prefilled syringe. You can review Lucentis® Vial for a reference product used in similar conditions. Brolucizumab is another option for some adults with wet AMD; see Beovu® Pre Filled Syringe to learn about this alternative. Your retina specialist decides which therapy fits your needs.
Pricing and Access
Canadian-sourced options can help you compare costs for brand biologics. Many customers ask about Eylea price and how it compares to clinic acquisition costs. We also list Aflibercept price for reference when available. Check our catalog to view current options that Ships from Canada to US, then discuss purchase logistics with your clinic if they request you bring a dose. For potential offers, see our Promotions page. We use encrypted checkout to help protect your information.
Savings vary by product and market factors. For disease education, you can also browse Diabetic Retinopathy and Macular Edema From Retinal Vein Occlusion resources while planning care with your prescriber.
Availability and Substitutions
Supply can change. Clinics may request a particular presentation, or a prescriber may recommend a suitable alternative if a specific item is unavailable. Some practices also use higher-strength aflibercept when appropriate; listings for aflibercept 8 mg may appear based on market approvals and stock. If the exact presentation is not listed, ask your clinician about acceptable substitutions that meet your treatment plan.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults with wet AMD, DME, or RVO-related macular edema who can attend regular visits. It may not suit people with active eye infection or significant intraocular inflammation. If you cover medicine yourself, you might compare Eylea cash price to clinic-supplied options. Ask your specialist about multi-visit planning to reduce travel time. Ordering multiple doses is clinic-dependent; many offices prefer to receive and store products directly. Set refill reminders aligned to your appointment cycle.
Questions to Ask Your Clinician
- Condition fit: Is this anti-VEGF the right choice for my diagnosis?
- Visit plan: How many loading doses will I need at first?
- Monitoring: Which imaging or tests guide interval changes?
- Safety: What symptoms after injection require urgent contact?
- Alternatives: If response is limited, what other therapies could we try?
- Logistics: Should the clinic order the product, or should I bring it?
- Travel: How do we schedule visits around trips or seasonal stays?
Authoritative Sources
Manufacturer Product InformationFDA DailyMedHealth Canada Drug Product Database
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What conditions does Eylea treat?
Aflibercept is used for several retinal diseases. It is approved for neovascular (wet) age-related macular degeneration, diabetic macular edema, and macular edema following retinal vein occlusion. In some regions, clinicians also use it for myopic choroidal neovascularization according to labeling. Your retina specialist confirms whether your diagnosis fits and which schedule is appropriate based on your eye exam and imaging results.
How often are injections given at the start?
Treatment usually begins with more frequent visits, then intervals may extend. For wet AMD, many plans start with a series of monthly doses before moving to longer gaps if the eye is stable. For diabetic macular edema or vein-occlusion–related swelling, frequency is tailored to your response and imaging. Your specialist follows the official label and your clinical findings to set the schedule.
What side effects should I watch for after an injection?
Mild eye discomfort, irritation, floaters, or a small red spot on the white of the eye can occur. Contact the clinic urgently if you have severe eye pain, significant redness, sudden vision loss, or many new floaters, which could signal infection or retinal detachment. Your care team will provide post-procedure instructions and follow-up steps to reduce risks and monitor recovery.
Can I drive or work right after a clinic visit?
Vision may be blurry after dilation and the procedure, so many people arrange a ride home. Sensitivity to light can persist for a few hours. Avoid strenuous tasks until your vision clears. Your specialist may advise protective steps for a short period, such as avoiding water in the eye or skipping contact lenses that day. Follow the clinic’s guidance for the safest recovery.
What is different about higher-strength aflibercept?
Some markets have a higher-strength presentation that allows clinicians to consider longer intervals for eligible patients, following the label. The decision to use a higher-strength option depends on your diagnosis, imaging, and response to prior dosing. Your retina specialist will discuss whether you could benefit, or whether a standard strength or a different anti-VEGF medicine would better fit your goals.
Is this medicine self-administered at home?
No. Intravitreal injections are performed by an ophthalmologist or retina specialist in a controlled setting. The clinic prepares the eye, uses sterile technique, and monitors you after the procedure. If you are asked to bring a dose, the pharmacy supplies handling instructions, and the clinic manages preparation and injection. Do not attempt to use this product yourself at home.
Will my insurance cover it if I purchase through a pharmacy?
Coverage policies vary and can be complex for clinic-administered biologics. Some plans reimburse clinic-acquired drugs, while others may consider pharmacy-dispensed products under medical or pharmacy benefits. Ask your clinic and insurer how claims are handled for buy-and-bill versus pharmacy dispensing. Your clinic may guide the most practical route for your situation based on their protocols.
