Humulin® R Vial for Mealtime and Correction Insulin Therapy

What Humulin® R Is and How It Works

Humulin® R is human regular insulin used to control blood glucose around meals and for correction doses. It is available as a humulin r 100 units ml vial (often a humulin r 10ml size) and as a concentrated humulin r 500 units ml vial for patients with high insulin needs. Many compare Humulin R Vial price options and look for Humulin R Vial without insurance choices when planning ongoing therapy. You can buy Humulin R Vial through our pharmacy service for US delivery.

Youdrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and licensed pharmacists review prescriptions before dispensing. We also work with licensed, vetted international partner pharmacies to source authentic brand medicines, offering a wide range at sensible, affordable pricing.

Humulin R is a short-acting insulin. After subcutaneous injection, onset is about 30 minutes, with a peak at 2 to 4 hours and duration near 5 to 8 hours for U-100. The U-500 formulation is five times as concentrated and lasts longer in many patients. Regular insulin helps move glucose from blood into tissues and suppresses liver glucose output.

Indications include type 1 and type 2 diabetes where mealtime coverage is needed. Administration is subcutaneous; intravenous use occurs in clinical settings when supervised by healthcare professionals. The insulin r vial is clear and colorless; do not use if it appears cloudy, thickened, or contains particles.

Dosage and Usage

• Administration timing: For U-100, administer subcutaneously about 30 minutes before starting a meal. Dose is individualized based on carbohydrate intake, premeal blood glucose, and insulin sensitivity.
• Correction dosing: Follow a prescribed correction scale to address high readings between meals or at mealtime.
• U-500 dosing: The humulin r u500 vial is intended for patients requiring ≥200 units/day. Typical schedules are two or three injections daily, 30 minutes before meals. Use a U-500 syringe (or dedicated device) to prevent dosing errors.
• Preparation: Inspect vial for clarity. Use a new sterile needle and the correct insulin syringe. For U-100, use U-100 syringes; for U-500, use U-500 syringes. Confirm concentration before drawing a dose.
• Injection steps: Clean the stopper, draw air equal to the dose, inject air into vial, withdraw the correct units, remove bubbles, and inject subcutaneously into recommended sites.
• Injection sites: Abdomen, thigh, buttock, or upper arm. Rotate within a region to reduce lipodystrophy; avoid injecting into areas of lipohypertrophy or irritation.
• Missed dose: If a mealtime dose is missed but eating now, administer as directed. If it is near the next scheduled dose, skip the missed dose to reduce hypoglycemia risk. Do not double doses.
• Mixing: Regular insulin may be mixed with NPH if directed, drawing clear (regular) before cloudy (NPH). Do not mix with insulin glargine or degludec. Do not share needles or syringes.
• Devices: Not for use in an insulin pump unless both your prescriber and pump labeling allow regular insulin. Intravenous use is for clinical supervision only.

• Unopened storage: Refrigerate at 2–8 °C (36–46 °F). Do not freeze. Keep in the original carton, protected from light.
• In-use U-100 vial: Store at room temperature below 30 °C (86 °F) for up to 31 days, or refrigerated for the same period. Do not expose to heat or direct sunlight.
• In-use U-500 vial: Store at room temperature below 30 °C (86 °F) for up to 40 days. Do not refrigerate after first use unless directed by labeling.
• Travel: Keep vials in an insulated bag with cool packs, not in direct contact with ice. Carry insulin and supplies in your hand luggage. Bring extra needles and syringes.
• Handling: Do not use if solution is cloudy or thick, or if the seal is broken. Keep out of reach of children.
• Shipping: We use prompt, express, cold-chain shipping to maintain temperature control in transit.

Benefits and Savings

Humulin R provides reliable prandial control with a predictable profile. Many patients appreciate the flexibility for correction dosing and the availability of a concentrated option in the humulin r 500 vial for marked insulin resistance. The vial format supports precise dose adjustments and broad syringe compatibility when the correct syringe is used.

Ordering from Youdrugstore helps you access Canadian pricing. Typical savings are 60–80% compared with many US retail prices, which supports long-term therapy planning. This can be especially helpful if you are paying Humulin R Vial cost out of pocket or managing expenses without insurance. We also support discreet US delivery and responsive service during office hours.

Looking for deals? See current Humulin R Vial coupon options on our promotions page. Multi-month supplies and occasional bulk promotions can lower the per-month expense, and we can send helpful reorder reminders before you run low.

Side Effects and Safety

• Hypoglycemia (shakiness, sweating, hunger, fast heartbeat, headache, confusion)
• Injection-site reactions (redness, itching, mild pain)
• Weight gain with continued use
• Edema or fluid retention
• Lipodystrophy or localized thickening at injection sites
• Allergic skin reactions (rash, pruritus)
• Hypokalemia in susceptible patients

Serious reactions can include severe hypoglycemia requiring assistance, generalized allergy, or significant hypokalemia. Risk of low blood sugar increases when combined with insulin secretagogues such as sulfonylureas or with insulin itself; dose adjustments and monitoring may be needed. Avoid use during episodes of hypoglycemia. Educate on U-500 dosing to prevent mistakes.

Onset Time

For U-100 Humulin R, glucose-lowering begins about 30 minutes after injection, with peak effect between 2 and 4 hours. Many patients see better pre- and post-meal readings within the first days as dosing is adjusted. Full optimization may take one to two weeks as patterns are reviewed and correction scales are refined.

For U-500, onset is similar but duration is longer, often covering a meal and extended postprandial period. Stabilization may require several days of consistent dosing and careful titration to balance efficacy and hypoglycemia risk.

Compare With Alternatives

Basal insulin: Insulin glargine provides steady background control with once-daily dosing for many patients. Pairing a basal insulin with prandial Humulin R is a common regimen. You can review Lantus® Vial to compare basal options and vial handling.

Rapid-acting insulin: Insulin lispro has a faster onset, typically injected right before eating. Some patients prefer a rapid analog, while others use regular insulin timing 30 minutes before meals. Compare vial and cartridge formats by visiting Humalog® Vial or exploring pen options if suitable.

Combination Therapy

• Basal-bolus: Basal insulin once daily plus Humulin R for meals and corrections.
• With metformin: Continue metformin to support insulin sensitivity.
• With GLP-1 receptor agonists: May reduce prandial insulin needs; monitor and adjust.
• With SGLT2 inhibitors: Monitor hydration and ketone risk during illness; adjust insulin as directed.
• With sulfonylureas: Consider reducing sulfonylurea dose to lower hypoglycemia risk.

Patient Suitability and Cost-Saving Tips

Humulin R may suit adults and children who need mealtime insulin, as well as those who require a concentrated formulation in the humulin r 500 vial. It should not be used during a current hypoglycemic episode, and it is contraindicated in patients with a known hypersensitivity to human insulin or formulation components. Dose needs can change with renal or hepatic impairment, illness, or changes in activity.

Cost management matters for long-term care. If you pay the Humulin R Vial cash price, consider multi-month fills to reduce shipping frequency and per-month costs. We offer reorder reminders and promotions throughout the year. These options can help when seeking Humulin R Vial without insurance support. When you order Humulin R Vial, keep your prescription current to avoid delays.

Authoritative Sources

Eli Lilly Humulin R Prescribing Information (U-100 and U-500)

FDA Drug Label: Humulin R U-100

Health Canada Drug Product Database: Humulin R

Order Humulin® R from Youdrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This content is educational and does not replace professional medical advice. Always follow your prescriber’s directions and the official product labeling.