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Imfinzi® Injection for Lung Cancer
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Imfinzi® is a prescription PD-L1 immunotherapy used for certain cancers. This page explains what it is, who it may suit, and how it is given. We support US delivery from Canada so you can review options for Imfinzi without insurance and discuss next steps with your care team.
What Imfinzi Is and How It Works
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
Imfinzi® (durvalumab) is an immune checkpoint inhibitor that targets PD-L1. By blocking PD-L1, it can help your immune system recognize and attack cancer cells. It is administered as an intravenous infusion in a clinic or hospital. This medicine is used alone or with chemotherapy, depending on the cancer type and treatment plan. It is not a self-injection and is supervised by a healthcare professional.
Durvalumab belongs to the class of PD-1/PD-L1 inhibitors. It may be continued as maintenance therapy after chemoradiation in some settings or started with chemotherapy in others. Treatment plans vary by indication, prior therapy, and your clinician’s guidance. For background on this class of therapy, see our article on Immunotherapy For Cancer.
Who It’s For
This therapy is used in several cancers, including non-small cell lung cancer and extensive-stage small cell lung cancer, based on approved uses. Some patients with biliary tract cancer may receive it in combination with chemotherapy. The specific indication and regimen are determined by your prescriber.
People with autoimmune disease, a history of organ transplant, or active infections require careful evaluation before starting treatment. If you are pregnant, planning pregnancy, or breastfeeding, discuss risks and timing with your clinician.
For search clarity and education, some patients explore Imfinzi lung cancer to learn where this therapy may fit in care pathways. For condition background, visit our categories on Non Small Cell Lung Cancer and Small Cell Lung Cancer. You can also read Lung Cancer Awareness for general education.
Dosage and Usage
Durvalumab is infused intravenously, typically over about an hour. Dosing schedules vary by indication and patient factors. Many adults receive therapy at regular intervals, often every two or four weeks. Your infusion schedule, duration, and any combination with chemotherapy are set by your oncology team using official labeling.
Before each infusion, your care team may check labs and assess symptoms. They may adjust the timing around holidays, procedures, or side effect management. If you are receiving Durvalumab in lung cancer, your team will align dosing with your concurrent or prior treatments and clinical status.
Do not change or skip any infusion without medical guidance. Tell your clinician about new symptoms, especially respiratory issues, diarrhea, rash, eye problems, jaundice, or severe fatigue. Premedications may be used if you had an infusion reaction previously.
Strengths and Forms
Durvalumab is supplied in single-use vials for IV infusion. Common presentations include fixed-dose options suitable for adults meeting weight criteria or weight-based dosing per the label. Availability can vary by market and by the oncology protocol your prescriber selects.
For reference across sources, one labeled presentation often discussed is Durvalumab 1500 mg given at defined intervals for certain adult patients. Your oncology team will choose the appropriate vial configuration and dosing plan.
Missed Dose and Timing
If an infusion is missed, contact your clinic as soon as possible to reschedule. Timing is guided by your prescriber, who may adjust the plan based on how much time has passed and your recent labs or symptoms. Do not try to compensate for a missed infusion without medical advice.
Storage and Travel Basics
Clinics store this medicine refrigerated and protected from light, following the label. Do not freeze. Avoid shaking vials. At home, patients typically do not hold vials, since preparation and administration occur at an infusion center.
If you must transport a dose arranged by your clinic or specialty pharmacy, follow the written instructions closely. Keep it in the original packaging until preparation. Use a cooler or thermal container if instructed. Bring supporting documents when traveling. Keep medicines out of reach of children and pets.
Benefits
This treatment can allow your immune system to better identify and fight cancer cells. It may be used after chemoradiation to help maintain control, or alongside chemotherapy in certain cancers. Infusions at planned intervals can simplify scheduling once a routine is established. Many patients appreciate that no daily tablets are needed for this regimen.
Side Effects and Safety
- Fatigue or low energy
- Cough or shortness of breath
- Diarrhea or abdominal discomfort
- Skin rash or itching
- Decreased appetite or nausea
- Muscle or joint pain
- Infusion-related reactions
Serious risks can include immune-related effects, such as pneumonitis, hepatitis, colitis, endocrinopathies (including thyroid or adrenal issues), nephritis, severe skin reactions, and ocular inflammation. Early recognition matters. Seek urgent care for chest pain, severe shortness of breath, persistent diarrhea, yellowing skin or eyes, vision changes, or severe rash. Your team may hold treatment and use corticosteroids or other medicines to manage immune-mediated reactions.
Drug Interactions and Cautions
Tell your prescriber about all medicines and supplements you take. Live vaccines are generally avoided during therapy. Long-term immunosuppressants may influence how immunotherapy works. Your team will consider steroid timing if needed to treat side effects. Patients with active autoimmune disease, prior transplant, or uncontrolled infections require individualized risk assessment.
Alcohol, smoking, and herbal products can complicate care by affecting organs or other therapies. Share complete information with your oncology team so they can coordinate safely.
What to Expect Over Time
Your clinician may schedule infusions and regular assessments over months. You will have lab monitoring and symptom checks before each dose. Some people feel tired for a day or two after an infusion, while others feel stable. Report new symptoms promptly, because immune-related effects can occur at any time during therapy.
This medicine is used for different cancers and stages, including Durvalumab small cell lung cancer settings when approved. Progress is assessed with imaging, labs, and clinical exams. Your team will discuss when to continue, pause, or stop therapy. Adherence to visits and clear communication help your clinicians respond early to any changes.
Compare With Alternatives
Treatment choices depend on tumor type, stage, biomarkers, and prior therapy. In certain lung cancers driven by EGFR mutations, targeted options may be used instead of or before immunotherapy. Two examples we carry include Tagrisso® and Lorbrena®. These are not interchangeable with immunotherapy; your oncologist selects based on mutation testing and clinical guidelines.
Pricing and Access
We provide Canadian pharmacy transparency so you can compare Imfinzi price and discuss options with your clinic. Many patients look for Durvalumab Canadian pricing to understand potential savings if paying cash. We offer clear product listings and secure checkout. For current offers, visit our Promotions page. Orders include US shipping from Canada with tracking. Final costs depend on dose, number of vials, and your prescribed schedule.
Availability and Substitutions
Supply can vary by strength and market demand. If a specific vial size is unavailable, your prescriber may recommend an alternative or a different configuration to achieve the ordered dose. We also list other oncology medicines in our Cancer category. As applicable, purchases are prescription required and verified.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults whose cancer type and stage match labeled indications or established protocols. It may not be appropriate for people with uncontrolled autoimmune conditions, active infections, recent organ transplant, or severe uncontrolled lung disease without careful specialist oversight. Discuss fertility, contraception, and breastfeeding considerations with your clinician.
To manage expenses, coordinate multi-visit planning with your infusion center. Align refills with scheduled cycles when possible. Ask your clinic about institutional assistance programs and financial counseling. Consider keeping a simple log for appointments, labs, and invoices. If your oncology team requests a quote, we can provide itemized details for your records. If you are comparing options beyond insurance, your clinic can help interpret the price of durvalumab and dosing needs for your plan.
Questions to Ask Your Clinician
- Goals of therapy: maintenance, first-line, or after prior treatment
- Expected schedule: how often infusions occur and for how long
- Monitoring plan: which labs and imaging will be used
- Side effect signs: which symptoms require urgent contact
- Vaccines and timing: which to avoid during treatment
- Fertility and pregnancy: recommended precautions and timelines
- Travel plans: coordinating visits and documentation
Authoritative Sources
Prescribing Information (AstraZeneca)
Health Canada Drug Product Database
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How is Imfinzi given and how long does an infusion take?
This medicine is administered by intravenous infusion in a clinic or hospital. A nurse prepares and monitors the infusion under your oncologist’s orders. The infusion itself typically takes about an hour, though the total visit can be longer due to check-in, labs, and post-infusion observation. Schedules vary by indication and overall plan. Your team will decide the dosing interval and length of therapy based on labeling, your response, and tolerability.
Which cancers is durvalumab approved to treat?
Durvalumab is a PD-L1 inhibitor used in specific settings for non-small cell lung cancer, extensive-stage small cell lung cancer, and certain biliary tract cancers when combined with chemotherapy. Approvals can differ by country. Your oncologist will confirm whether your diagnosis and prior treatments align with the approved indication in your region and whether biomarkers or imaging are needed before starting therapy.
What side effects should I watch for during treatment?
Common effects include fatigue, cough, diarrhea, rash, itching, nausea, and infusion reactions. Immune-related issues can affect lungs, liver, gut, hormones, kidneys, skin, or eyes. Call your clinic promptly for shortness of breath, persistent diarrhea, yellowing skin or eyes, severe rash, vision changes, or chest pain. Your team may pause therapy and manage symptoms with steroids or other medicines if needed.
Can I receive vaccines while on immunotherapy?
Live vaccines are generally avoided during treatment. Inactivated or non-live vaccines may be considered if your oncology team agrees. Timing matters; some vaccines are best given before therapy begins. Always check with your prescriber before any vaccination, including flu or COVID-19 shots, to ensure the plan fits your treatment schedule and immune status.
How does durvalumab differ from targeted therapies?
Durvalumab helps your immune system recognize cancer cells by blocking PD-L1. Targeted therapies act on specific gene changes in the tumor, such as EGFR or ALK alterations. They are used in different clinical situations and are not interchangeable. Your oncologist will use biomarker testing and treatment history to decide which strategy fits your cancer type and stage.
What if I miss a scheduled infusion appointment?
Contact your infusion center as soon as possible to reschedule. Do not try to make up a dose on your own. Your team will advise on timing based on how long it has been, your lab results, and any recent side effects. Keeping a calendar and reminder system can help reduce missed visits and coordinate transportation or caregiver support.
How should Imfinzi be stored or handled at home?
Patients typically do not store vials at home. Clinics keep it refrigerated and protected from light per labeling. If your clinician arranges temporary patient transport, follow written instructions strictly, keep the package in the original container, and avoid shaking or freezing. Use insulated carriers if directed, and bring all documents when traveling to appointments.
