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Inclunox® HP Injection for DVT and PE
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Low molecular weight heparin helps reduce the risk of harmful clots. This page explains how this prescription therapy is used, stored, and obtained with US delivery from Canada, even if you are paying without insurance.
What Inclunox Is and How It Works
Inclunox® HP is an enoxaparin sodium injection, a low molecular weight heparin used to prevent and treat blood clots in veins and lungs. It enhances antithrombin activity, which reduces Factor Xa and, to a lesser extent, thrombin. The result is a more predictable anticoagulant effect than unfractionated heparin. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This medicine is given by subcutaneous injection. It is commonly used around surgery, during periods of limited mobility, and in certain heart conditions such as unstable angina or some myocardial infarctions. For condition details, see our category page for Blood Clot Dvt Pe.
Who It’s For
This treatment is indicated to help prevent deep vein thrombosis, including after orthopedic or general surgery, and to treat existing DVT with or without pulmonary embolism. It may also be used in acute coronary syndromes and some ST-elevation myocardial infarctions as directed by a prescriber.
People who should avoid a low molecular weight heparin injection include those with active major bleeding or a history of heparin-induced thrombocytopenia. Use caution with severe kidney impairment, recent spinal or epidural anesthesia, or bleeding disorders. It is porcine-derived; those with pork sensitivity should discuss risks with a clinician. Always follow your prescriber’s advice and the official label.
Dosage and Usage
Your prescriber will determine the dose based on your condition and weight. Typical approaches include once-daily or twice-daily schedules. For DVT treatment, weight-based dosing is commonly used. For surgical prophylaxis, fixed doses are often used. Hospital protocols may differ by indication and patient factors.
Administration tips for Inclunox HP injection:
- Give subcutaneously in the abdomen; do not inject into muscle.
- Rotate injection sites; avoid bruised or scarred areas.
- Do not expel the air bubble from the prefilled syringe unless instructed by a clinician.
- Pinch a skin fold, insert the needle vertically, inject slowly, and release the fold before removing the needle.
- Do not rub the site after injecting.
Follow your prescriber’s instructions and the patient leaflet. If you are unsure about technique, ask your healthcare professional for guidance.
Strengths and Forms
The product is supplied as Inclunox HP prefilled syringes designed for subcutaneous use. Higher-potency presentations commonly published for this line include 100 mg/mL, 120 mg/mL, and 150 mg/mL. Availability can vary by lot and jurisdiction. Your exact strength, fill volume, and needle specifications depend on the dispensed item and your prescription.
| Form | Use |
|---|---|
| Prefilled syringes | Single-use, ready-to-inject doses |
Final selection is based on the prescribed dose and duration. If your prescribed strength is not listed, we may contact your prescriber for alternatives according to the prescription.
Missed Dose and Timing
If you miss a dose, take it when remembered the same day. If it is almost time for the next scheduled dose, skip the missed one. Do not double up. If you miss more than one dose, contact your prescriber for advice. Hospital-managed dosing may follow facility protocols; defer to those instructions when applicable.
Storage and Travel Basics
Store syringes at room temperature, away from excessive heat and moisture. Keep in the original carton to protect from light. Do not freeze. Keep out of reach of children and pets. Do not use if the solution is discolored or contains particles, or if the syringe is damaged.
For travel, pack syringes in a carry-on bag with your prescription label and, if available, a travel letter. Use a rigid sharps container for used needles while away from home. Allow extra time for security checks. When crossing borders, keep medications in original packaging with matching identification. A prescription is required and verified.
Pen Handling and Sharps Disposal
This product uses prefilled syringes, not a pen device. Inspect the syringe before use. Follow aseptic technique, choose a clean site, and inject as instructed. Never share syringes.
Dispose of used syringes in a puncture-resistant, FDA-cleared sharps container. When full, follow local rules for disposal or take-back programs. Do not place loose needles in household trash or recycling.
Benefits
This therapy offers predictable anticoagulation with subcutaneous dosing. Many regimens are once or twice daily, which can simplify routines. Prefilled syringes reduce preparation steps compared with vial-and-syringe methods. Compared with older unfractionated heparin protocols, fewer routine lab checks are typically needed, though certain patients may require monitoring as guided by the prescriber.
Side Effects and Safety
- Injection site pain, redness, or bruising
- Nosebleeds or gum bleeding
- Easy bruising or minor bleeding
- Fatigue or mild anemia
- Low platelets or elevated liver enzymes
Serious risks include major bleeding, spinal or epidural hematomas with neuraxial anesthesia, and heparin-induced thrombocytopenia. Seek urgent care for signs of uncontrolled bleeding, severe headache, sudden weakness, black stools, or allergic reaction. If you receive spinal or epidural procedures, your clinician will plan timing to reduce hematoma risk. For context on anticoagulant effects, you can read our article Side Effects Of Eliquis (general education).
Drug Interactions and Cautions
Medicines that raise bleeding risk can interact with this treatment. These include other anticoagulants, antiplatelets such as aspirin or clopidogrel, many NSAIDs, and some antidepressants that affect platelets. Certain herbal products like ginkgo, garlic, and high-dose fish oil may also increase bleeding tendencies. Tell your prescriber about all medicines and supplements you use.
Kidney impairment can increase exposure and bleeding risk; dose adjustments may be needed per the official label. Extra caution is advised around spinal or epidural anesthesia. If you have a history of HIT, your prescriber will consider other options. Do not start, stop, or change any medicines without professional guidance.
What to Expect Over Time
Anticoagulant effect begins after injection and persists for the intended dosing interval. Bruising at the site can occur. Many people settle into a consistent routine over several days with support from their care team. You may have periodic labs when clinically indicated. Continue therapy as prescribed, even if you feel well, unless your clinician instructs a change. Proper technique and site rotation can help reduce local reactions.
Compare With Alternatives
Several enoxaparin brands provide similar clinical utility. Many people discuss a Lovenox generic alternative with their prescriber. We also carry comparable options such as Redesca® Hp, Elonox® Hp, and Noromby® Hp. Your clinician will choose based on indication, dosing needs, and your medical history.
Pricing and Access
Canadian pharmacy sourcing can help with affordability compared with some local options. Explore Inclunox HP Canadian pricing and availability on this page. If you’re looking to order Inclunox HP online, you can add your prescribed strength to your cart and upload your prescription during checkout. For potential offers, see our current Promotions. We provide secure checkout and Ships from Canada to US fulfilment to your address after verification.
Savings CTA: Compare Canadian rates to your local cash-pay amounts to understand potential savings. Pricing CTA: Select your strength to view today’s pricing and supply options before placing your order.
For broader browsing, visit our Other category.
Availability and Substitutions
Supply can vary by strength and pack size. If your requested item is unavailable, your prescriber may recommend an equivalent enoxaparin brand or adjust to an appropriate presentation. We cannot provide timelines for restocks, but we will coordinate with your clinician if a substitution is clinically suitable.
Patient Suitability and Cost-Saving Tips
Adults who need short-term or extended anticoagulation for DVT, PE, or specific cardiac indications may be candidates. People with active bleeding, recent spinal procedures, severe uncontrolled hypertension, or a history of HIT are not suitable. Those with kidney impairment require careful assessment.
- Plan refills early: set reminders to avoid gaps.
- Ask your prescriber about multi-month supplies to reduce per-fill fees.
- Keep all supplies together: syringes, alcohol swabs, and a sharps container.
- Learn proper technique to minimize waste and site irritation.
- Carry documentation when traveling to prevent delays.
Questions to Ask Your Clinician
- Is this the right anticoagulant for my condition and kidney function?
- What dose and schedule should I follow at home?
- How should I time doses around surgery, dental work, or injections?
- Which over-the-counter pain relievers are safest with my therapy?
- Do I need any blood tests, and how often?
- What signs of bleeding should prompt urgent care?
Authoritative Sources
- DailyMed: Enoxaparin Injection
- Health Canada Drug Product Database
- Manufacturer: Lovenox Prescribing Info
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How is enoxaparin given at home?
Enoxaparin is usually injected just under the skin of the abdomen. Choose a clean site at least a few inches from the navel, rotate sites, and avoid bruised or scarred areas. Pinch a skin fold, insert the needle straight in, inject slowly, and remove at the same angle. Do not rub the site afterward. Never inject into muscle. Your care team can demonstrate technique and provide a patient leaflet with step-by-step instructions.
Can I use pain relievers while taking this anticoagulant?
Some pain relievers increase bleeding risk. Aspirin, many NSAIDs like ibuprofen or naproxen, and certain combination products may not be appropriate. Acetaminophen is often preferred for occasional pain, but you should confirm with your prescriber. Always check labels for hidden aspirin or NSAIDs. If you need regular pain control, ask your clinician to recommend options that fit your therapy and medical history.
What should I do if I see bruises or bleeding?
Small bruises at the injection site are common. Apply gentle pressure after injecting. For nosebleeds or gum bleeding, use local measures and monitor. If bleeding is heavy, persistent, or you notice signs like black stools, coughing up blood, severe headache, or sudden weakness, seek urgent care. Contact your prescriber for further guidance, and bring a list of all medicines and supplements to discuss potential contributors.
Do I need blood tests while using this medicine?
Routine anti-Xa monitoring is not required for most adults on fixed dosing. However, certain situations may call for checks, such as kidney impairment, extremes of body weight, pregnancy, or prolonged therapy. Your clinician will decide if monitoring is needed. You may have periodic blood counts to watch for anemia or low platelets. Always follow the plan set by your healthcare professional.
How should I store prefilled syringes during travel?
Keep syringes in original cartons at room temperature and away from direct sun. Pack them in a carry-on with your prescription label and, if available, a travel letter. Use a rigid sharps container for used needles and follow local disposal rules. Allow extra time at security checkpoints. Do not freeze the medication or leave it in a hot car.
Can this therapy be used during pregnancy or after delivery?
Enoxaparin is commonly considered in pregnancy for certain clotting risks, but decisions are individualized. Dosing and timing around delivery require coordination with obstetric and anesthesia teams to reduce bleeding and spinal/epidural hematoma risk. Do not start, stop, or adjust therapy without guidance from your clinician. Share your full history, including prior clots and any bleeding issues.
What if I’m scheduled for spinal or epidural anesthesia?
These procedures increase the risk of spinal or epidural hematomas when combined with anticoagulants. Your healthcare team will plan timing of doses relative to needle placement and catheter removal. Tell all clinicians about your injections, including the last dose and strength. Report any back pain, numbness, or weakness immediately after the procedure. Follow the official label and your clinician’s instructions precisely.
