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Januvia® Tablets for Type 2 Diabetes
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Januvia is a prescription DPP-4 inhibitor used to help control blood sugar in adults with type 2 diabetes. Many patients compare their options for US delivery from Canada to manage costs without insurance. If your prescriber recommends it, we help you order with clear guidance and pharmacy support.
What Januvia Is and How It Works
Januvia® contains sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. It helps your body increase insulin release and lower glucagon levels when glucose is high. This medicine is used along with diet and exercise to improve glycemic control in adults with type 2 diabetes. It is not for type 1 diabetes or diabetic ketoacidosis.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This treatment may be used alone or with other agents such as metformin or insulin. It can be taken with or without food, which simplifies daily routines. The mechanism targets incretin hormones, so effects are glucose-dependent and may reduce hypoglycemia risk when used without insulin or sulfonylureas.
Who It’s For
This therapy is for adults diagnosed with type 2 diabetes who need additional glucose control with diet and exercise. It may be prescribed as initial therapy or added to existing regimens. People with a history of pancreatitis, severe kidney impairment, or serious allergic reactions to sitagliptin should discuss risks with a clinician before use. Type 2 Diabetes resources can help you learn more about the condition and treatment choices.
Sitagliptin phosphate 100 mg is sometimes chosen when prescribers consider once-daily convenience. Patients with impaired renal function often require a different dose according to the official label.
Some individuals may use it with other oral agents. Many start with metformin; others need combinations based on A1C goals and tolerability. Lifestyle measures remain essential alongside any prescription therapy.
Dosage and Usage
The usual adult regimen is once daily, taken at the same time each day. You may take it with or without food. If you have kidney impairment, the product label outlines dose adjustments; your prescriber will determine an appropriate strength. Do not split, crush, or chew the tablets unless the label clearly allows it.
Sitagliptin 100 mg tablet is a common dose when renal function is normal. Your healthcare professional will select a different strength if needed based on lab results and your overall plan. Always follow the instructions on your prescription label.
When used together with insulin or a sulfonylurea, your clinician may monitor for low blood sugar. Keep a consistent routine for meals and physical activity to support stable control. Read the patient information leaflet that accompanies your medicine.
Strengths and Forms
This medicine is supplied as film-coated oral tablets. Common strengths include 25 mg, 50 mg, and 100 mg. Availability may vary by manufacturer and market.
Some prescribers choose Januvia 100 mg tablets for adults with adequate renal function who need once-daily therapy. Tablet color and markings can differ by strength and manufacturer.
Missed Dose and Timing
If you miss a dose, take it when you remember on the same day. If it is nearly time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time. Set reminders or use a pill organizer to support adherence.
Storage and Travel Basics
Store tablets at room temperature in a dry place. Keep them in the original container with the label intact. Protect from moisture and keep out of reach of children and pets. Do not use tablets that are damaged or past their expiry date.
For travel, pack your prescription, a copy of your medication list, and your prescriber’s details. Keep tablets in hand luggage when flying. If you use a weekly pill case, bring at least one labeled pharmacy container as backup for identification. Review our Diabetes Care supplies for accessories that can help on the go.
Benefits
This class may help lower fasting and post-meal glucose when used with diet and exercise. Once-daily dosing offers convenience. It can be combined with other agents when a single therapy is not enough. When used without insulin or sulfonylureas, the risk of hypoglycemia is generally lower than with some other classes.
Side Effects and Safety
- Common cold symptoms
- Stuffy or runny nose
- Sore throat
- Headache
- Stomach discomfort
- Diarrhea or constipation
Serious but less common risks include pancreatitis, severe joint pain, allergic reactions such as angioedema, and skin reactions including blistering. Bullous pemphigoid has been reported in patients taking DPP-4 inhibitors. Stop the medicine and seek urgent care if you develop severe abdominal pain, difficulty breathing, swelling of the face or throat, or a widespread rash. Risk of low blood sugar increases when combined with insulin or a sulfonylurea. Kidney function should be assessed before initiation and monitored as directed.
Drug Interactions and Cautions
Concomitant use with insulin or insulin secretagogues can increase hypoglycemia risk. Your prescriber may adjust the background agent to reduce lows. Digoxin levels may rise when used together; monitoring may be considered. Tell your healthcare professional about all medicines, vitamins, and herbal products you take.
Do not use this treatment if you have a known hypersensitivity to sitagliptin. Discuss a history of pancreatitis, gallstones, or high triglycerides with your clinician. Follow the official label for complete warnings and precautions.
What to Expect Over Time
You can expect your clinician to evaluate fasting and post-meal glucose and A1C over regular visits. Consistent daily dosing supports steady control. Many people also work on meal planning, physical activity, and sleep. If your goals are not met with one therapy, your prescriber may add or switch agents based on clinical guidelines. For healthy habits between appointments, see our article Reverse Prediabetes.
Compare With Alternatives
Other DPP-4 inhibitors may be suitable if you prefer a different option or have specific needs. Linagliptin, sold as Tradjenta, is used once daily and does not require renal dose adjustment. Some patients and prescribers consider an SGLT2 inhibitor when cardiovascular or kidney benefits are prioritized; Jardiance is one example. Combination products such as sitagliptin with metformin also exist and may reduce pill burden. Your prescriber will recommend options that match your health profile.
Pricing and Access
We display transparent options so you can compare strengths and brands. Januvia 100 mg price inquiries are common, and our team can help you review choices and typical cash-pay considerations. For time-sensitive needs, many customers value that orders Ships from Canada to US with clear tracking. See current pricing on the product page or contact support for help with your prescription.
Looking for extra value? Check our Promotions page for current site offers. Savings can vary by strength and supply size.
Availability and Substitutions
Supply can vary by strength and manufacturer. If your preferred option is unavailable, your prescriber may recommend a suitable alternative or a temporary change. Some patients ask about Generic for Januvia 100 mg; availability depends on market and prescriber guidance. If your clinician approves a substitution, you can review options such as Sitagliptin on our site.
Patient Suitability and Cost-Saving Tips
You may be a candidate if you have type 2 diabetes and your prescriber believes a DPP-4 inhibitor can help your plan. It is not for type 1 diabetes or diabetic ketoacidosis. People with a history of pancreatitis or serious hypersensitivity should discuss risks first. Kidney function is important for dose selection.
To stretch your budget, ask your prescriber if a multi-month fill is appropriate for you. Fewer refills may lower per-fill costs and reduce trips. Set refill reminders so you don’t run out unexpectedly. Review generics and combination options with your clinician if suitable. Our site offers secure checkout, and we maintain encrypted checkout to protect your information.
Questions to Ask Your Clinician
- Is a DPP-4 inhibitor appropriate for my A1C goals?
- How should my kidney function guide the strength you prescribe?
- Could I combine this with metformin or another class safely?
- What signs of pancreatitis or allergy should I watch for?
- How often should I check blood glucose while starting?
- Are there interactions with any of my current medicines?
- Would a multi-month supply be suitable for me?
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How does this medicine work in type 2 diabetes?
This therapy inhibits the DPP-4 enzyme, which increases active incretin hormones. Incretins help the pancreas release insulin and reduce glucagon when glucose is high. The effect is glucose-dependent, so it works mainly when sugars are elevated. It is used with diet and exercise to improve glycemic control in adults with type 2 diabetes. Your clinician will decide if this class is appropriate for you.
Can I take it with metformin or insulin?
Many adults use this medicine alone or together with other agents. It may be paired with metformin, an SGLT2 inhibitor, a thiazolidinedione, or insulin. The risk of low blood sugar can increase when combined with insulin or a sulfonylurea. Your prescriber will review your current regimen and monitoring plan. Always follow the label and pharmacy instructions.
What are common side effects and serious warnings?
Common effects include stuffy or runny nose, sore throat, headache, and mild stomach upset. Serious risks can include pancreatitis, allergic reactions such as angioedema, severe joint pain, and blistering skin reactions. Bullous pemphigoid has been reported with DPP-4 inhibitors. Seek urgent care for severe abdominal pain, swelling of the face or throat, or widespread rash.
How should I take the tablets?
Take the tablet once daily at the same time each day. You may take it with or without food. Swallow whole with water unless the patient leaflet says otherwise. If you have kidney problems, the official label outlines dose adjustments that your prescriber may apply. Do not change your dose on your own. Keep regular follow-ups to review glucose and overall control.
What if I miss a dose?
If you forget a dose, take it when you remember on the same day. If it is close to the next dose, skip the missed dose and resume your regular schedule. Do not double up doses. Setting an alarm or using a pill organizer can help prevent missed doses. Speak with your pharmacist if missed doses become frequent.
Who should avoid using this treatment?
People with a known hypersensitivity to sitagliptin should not use it. Those with a history of pancreatitis should discuss risks and symptom monitoring with their prescriber. It is not indicated for type 1 diabetes or diabetic ketoacidosis. Kidney function is important for dose selection, so testing and ongoing monitoring may be needed.
How do I store the tablets when traveling?
Keep tablets in the original labeled container at room temperature. Protect from moisture and keep away from children and pets. Carry your medication and a copy of your prescription in your hand luggage when flying. Consider a weekly pill case for convenience, and keep at least one pharmacy-labeled bottle for identification at security or customs.

