Jardiance® (empagliflozin) tablets for type 2 diabetes and heart failure

What Jardiance® Is and How It Works

Jardiance® (empagliflozin) is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It is used in adults with type 2 diabetes to improve blood sugar control. It also reduces the risk of cardiovascular death and hospitalization in adults with heart failure. This page explains Jardiance cost, uses, dosing, and safety so you can make an informed choice.

Jardiance® tablets are taken by mouth once daily. Typical strengths are 10 mg and 25 mg. The medicine increases glucose loss in urine by blocking SGLT2 in the kidneys. This lowers blood sugar and can reduce blood pressure and body weight. It also helps the heart and kidneys work with less strain.

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Dosage and Usage

Doctors often start at 10 mg once daily in the morning, with or without food. For type 2 diabetes, the dose may increase to 25 mg once daily if more control is needed. For heart failure, 10 mg once daily is commonly used. Kidney function, other medicines, and treatment goals guide dosing decisions.

• Take Jardiance® at the same time each day.
• Swallow tablets whole with water. Do not crush or chew.
• If a dose is missed, take it when remembered the same day. If the next dose is due, skip the missed dose. Do not double up.
• Drink enough fluids. Dizziness can occur if dehydrated, especially in hot weather or with diuretics.
• Store your tablets at room temperature, away from moisture and light, in the original bottle.
• For travel, pack extra tablets in your carry-on, keep the pharmacy label with you, and maintain storage at room temperature.

Dose adjustments or interruptions may be considered around major surgery, severe illness, or restricted food intake. Jardiance® is not used for type 1 diabetes or for diabetic ketoacidosis.

Benefits and Savings

Jardiance® lowers A1C by about 0.5% to 1% when used alone or with other agents. Many patients see modest weight loss and lower systolic blood pressure. In adults with type 2 diabetes and cardiovascular disease, empagliflozin reduced cardiovascular deaths in clinical trials. In heart failure, it lowers the risk of hospitalization and cardiovascular death across ejection fraction ranges.

Tablets are taken once daily, which supports adherence. No injections are needed. Many patients also value the cardiovascular and kidney-protection data seen in studies, though individual results vary.

Ordering from Youdrugstore can mean 60–80% savings compared with typical US prices. Our team supports simple reorders and can set friendly reminders so you never run low.

Side Effects and Safety

Most side effects are mild and improve over time. Serious events are uncommon but require quick medical attention. This list is not complete.

• Common: increased urination, thirst, dry mouth, genital yeast infections (vulvovaginal candidiasis, balanitis), urinary tract infections, mild nausea, constipation, or headache.
• Volume depletion: dizziness, low blood pressure, or fainting, especially in older adults, those on diuretics, or with low fluid intake.
• Hypoglycemia: more likely when used with insulin or sulfonylureas; dose adjustments of those agents may be needed by a prescriber.
• Genital/urinary infections: recurrent or severe infections may require treatment interruption.
• Ketoacidosis: rare euglycemic diabetic ketoacidosis can occur, often during illness, fasting, or reduced insulin. Symptoms include nausea, vomiting, abdominal pain, fatigue, and rapid breathing.
• Kidney issues: transient changes in kidney function can occur at start; rare acute kidney injury has been reported.
• Fournier’s gangrene: a very rare but serious infection of the perineum. Urgent care is required if symptoms arise (pain, swelling, fever).
• Allergic reactions: rash, hives, swelling, or difficulty breathing need immediate medical attention.

Patients with severe kidney disease, a history of recurrent ketoacidosis, or active genital infections may need a different approach. Pregnancy and breastfeeding require individualized discussion. Review all medicines, including diuretics, ACE inhibitors, ARBs, NSAIDs, and lithium, for interactions and volume effects.

Onset Time

Urinary glucose excretion increases with the first dose. Blood sugar reductions are measurable within days and stabilize over 1 to 2 weeks, with A1C effects assessed over 8 to 12 weeks. For heart failure, diuretic-like effects may appear in the first week, while improved symptoms and reduced hospitalizations are assessed over weeks to months.

Compare With Alternatives

Other SGLT2 inhibitors include dapagliflozin and canagliflozin. Dapagliflozin is marketed as Forxiga® in many markets and has similar glucose, heart failure, and kidney data with some label differences. Canagliflozin has comparable glycemic and organ outcomes but a distinct safety profile noted in its labeling.

Non-SGLT2 options include DPP-4 inhibitors like sitagliptin and combinations such as Janumet® (sitagliptin/metformin). These help glycemic control without the kidney glucose excretion mechanism. Choice depends on A1C goals, cardiovascular and kidney status, weight needs, hypoglycemia risk, and tolerance.

Combination Therapy

Jardiance® is often combined with metformin. It can be used with GLP-1 receptor agonists for additional A1C and weight effects. It is also used with insulin or sulfonylureas, though hypoglycemia risk rises with those agents. Blood pressure medicines and diuretics may need review because of volume changes from SGLT2 inhibition. Prescribers tailor combinations to goals and safety.

Patient Suitability and Cost-Saving Tips

Jardiance® suits many adults with type 2 diabetes who need better glycemic control, especially when heart or kidney protection is a priority. It is also used in heart failure regardless of diabetes status. It is not for type 1 diabetes or for treating ketoacidosis. Caution is needed in severe kidney impairment, frequent urinary or genital infections, dehydration, or with low-carbohydrate diets that raise ketosis risk.

To manage costs, consider a multi-month supply when appropriate. Ordering 90 days at once can lower the monthly price. You can turn on reorder reminders in your account so you have time to schedule delivery. For current deals and bulk options, see our Jardiance coupon page.

Youdrugstore offers brand medicines at Canadian prices with US shipping. We also stock alternatives if a prescriber recommends a change. Explore related conditions like Type 2 Diabetes and Heart Failure to learn more about treatment goals and monitoring.

Authoritative Sources

Learn more from the Official Jardiance website, the FDA Prescribing Information database, and the Health Canada Drug Product Database.

Ready to order? Youdrugstore provides careful pharmacist review and supports your questions by chat during office hours. We ship to the US with prompt, express, cold-chain shipping when needed, and pack discreetly for your privacy.

This content is for general information and does not replace medical advice. Always speak with a healthcare professional about diagnosis, treatment options, and dosing for your situation.