Lantus® Cartridges for Long-Acting Basal Insulin (U-100)

What Lantus® Is and How It Works

Lantus® (insulin glargine 100 units/mL) is a long-acting basal insulin for adults with type 1 or type 2 diabetes, and for pediatric patients with type 1 diabetes when prescribed. These U-100 Lantus Cartridges are multi-dose 3 mL cartridges designed for compatible reusable insulin pens. People often choose this format to lower their ongoing Lantus Cartridges price and for easier pen handling, even when buying without insurance.

Lantus® releases insulin slowly over about 24 hours. After subcutaneous injection, microprecipitates form in the subcutaneous tissue and dissolve gradually, providing a steady insulin level with no pronounced peak. Usual dosing is once daily at the same time each day. It can be used alone in type 2 diabetes or with rapid-acting insulin at meals in type 1 diabetes.

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Lantus® is injected subcutaneously in the abdomen, thigh, or upper arm. It must not be given intravenously, used in an insulin pump, or mixed or diluted with other insulins. The solution should be clear and colorless.

Dosage and Usage

• Typical initiation in type 2 diabetes: 10 units once daily or about 0.2 units/kg, then titrate to fasting glucose targets per your prescriber.
• Type 1 diabetes: use as basal insulin with mealtime rapid-acting insulin; total daily insulin is individualized.
• Titration: small dose increases (for example, 2 units every 3–4 days) until fasting targets are reached, as directed by the prescriber.
• Missed dose: take as soon as remembered on the same day, then resume the usual schedule. Skip if close to the next dose. Do not double.
• Compatible device use: confirm the cartridge fits the intended reusable pen model per manufacturer guidance.
• Injection steps (overview): inspect cartridge; attach a new sterile needle; prime per pen instructions; dial the dose; inject into recommended site; count the hold time; remove the needle and safely discard.
• Rotate injection sites to reduce lipodystrophy and cutaneous amyloidosis.
• Do not mix or dilute Lantus® in a syringe or cartridge, and do not transfer cartridge contents to a syringe.

• Store unopened cartridges in a refrigerator at 2–8 °C (36–46 °F). Do not freeze. Protect from light.
• In use: keep the cartridge in the pen at room temperature (generally below 25 °C/77 °F). Do not refrigerate an in-use pen. Discard 28 days after first use.
• Keep away from heat and direct sunlight. Do not use if frozen or if the solution becomes cloudy, colored, or contains particles.
• Travel: keep insulin in an insulated case with cold packs, not directly against ice. Carry a backup supply and spare needles in your hand luggage.
• Shipping: YouDrugstore ships insulin with prompt, express, cold-chain handling.

Benefits and Savings

Lantus® provides steady, 24-hour basal coverage with a flat profile for many patients. Once-daily dosing helps simplify regimens. Compared with intermediate-acting insulins, nocturnal hypoglycemia may be reduced when doses are matched appropriately. Cartridges let many people use a preferred pen style while managing the ongoing Lantus Cartridges cost.

Ordering from Canada can bring 60–80% savings versus typical U.S. prices, especially for multi-month supplies. You can buy Lantus Cartridges online and select quantities that fit your plan. Many customers also find value when purchasing without insurance, particularly when combining bulk pricing with sale periods.

We offer periodic promotions on select items; see our Lantus Cartridges coupon for current deals.

Side Effects and Safety

• Common: hypoglycemia (shakiness, sweating, fast heartbeat), injection-site reactions (redness, itching), lipodystrophy, weight gain, and mild edema.
• Less common: allergic reactions, rash, pruritus.
• Metabolic: hypokalemia can occur with insulin use.
• Device-related: bent or blocked needles can cause underdosing; always use a new needle.

Severe hypoglycemia is the most important risk and can be life-threatening. Risk increases with missed meals, increased activity, alcohol, renal or hepatic impairment, or when combined with prandial insulin or sulfonylureas. Fluid retention and heart failure may occur when insulin is used with thiazolidinediones. Stop and seek urgent care for generalized allergic reactions (widespread rash, swelling, difficulty breathing).

Onset Time

Lantus® begins to work about 1–2 hours after injection. It has no pronounced peak and provides near-constant activity over roughly 24 hours. Fasting glucose often improves within several days as basal doses are adjusted. A1C changes generally appear over 8–12 weeks as the regimen stabilizes.

Compare With Alternatives

Insulin glargine biosimilars, such as Basaglar (insulin glargine) or Semglee (insulin glargine), offer similar long-acting profiles. Doses are individualized when switching, and monitoring is needed to maintain fasting targets.

Some patients prefer vials for syringe use. If that suits your routine, see Lantus® Vial for the same U-100 insulin glargine in vial format.

Rapid-acting mealtime insulins are often paired with basal insulin. Options include Humalog® Vial (insulin lispro) or Apidra® Vials (insulin glulisine). These cover carbohydrate intake and correct hyperglycemia around meals, while Lantus® provides the background basal component.

Combination Therapy

• Basal-bolus: Lantus® once daily plus rapid-acting insulin at meals; adjust doses to reduce hypoglycemia risk.
• With metformin: common in type 2 diabetes; helps improve fasting and overall control.
• With SGLT2 inhibitors or GLP-1 receptor agonists: may support glycemic goals and weight management; insulin dose reductions may be needed.
• With sulfonylureas: consider lowering the sulfonylurea dose to reduce hypoglycemia risk.
• Do not mix Lantus® with other insulins in the same syringe or pen.

Patient Suitability and Cost-Saving Tips

Lantus® is indicated as basal insulin therapy for adults with type 1 or type 2 diabetes, and for pediatric patients with type 1 diabetes when prescribed. It is not for diabetic ketoacidosis treatment. Do not use during episodes of hypoglycemia or if there is a known hypersensitivity to insulin glargine or any component of the formulation.

Caution is required in renal or hepatic impairment, where dose reductions may be needed. Pregnancy and breastfeeding often require insulin; prescribers adjust regimens to maintain tight targets. Always verify pen compatibility before using cartridges, and check the solution is clear and particle-free.

To lower the Lantus Cartridges out of pocket expense, consider a multi-month supply. Bulk purchases can reduce the per-month cost, and sale events may add further savings. You can set gentle reorder reminders in your account so you do not run out. These steps help many people manage therapy even when buying Lantus Cartridges no insurance.

Authoritative Sources

Sanofi Lantus product information

Health Canada Drug Product Database (search “Lantus insulin glargine”)

FDA Prescribing Information for Lantus (insulin glargine)

Order Lantus® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This page is for education only and does not replace advice from your healthcare professional.