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Livtencity® Tablets for CMV Infection in Transplant Patients
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What Livtencity® Is and How It Works
Livtencity is an oral antiviral used to treat cytomegalovirus after organ or stem cell transplant. It targets CMV replication and is used when infection is refractory or resistant to other agents. This page explains how the treatment is used, who it may suit, and how to access US delivery from Canada. You can also review Livtencity cost without insurance and practical access tips.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
The active ingredient, maribavir, blocks the CMV UL97 protein kinase. By inhibiting this viral enzyme, the medicine can reduce viral activity in people with weakened immune systems after transplant. It is not indicated for use in people without CMV disease or for routine prevention unless directed by a prescriber.
For condition background and care pathways, see our overview of CMV Infection and browse related options in Antivirals.
Who It’s For
This treatment is intended for adults and certain adolescents after solid organ or hematopoietic stem cell transplant who have CMV infection that has not responded to other therapies. People with a known allergy to maribavir or any tablet components should avoid it. It has not been studied for CMV retinitis and is not a substitute for appropriate ophthalmic care.
Discuss risks if you are pregnant, could become pregnant, or are breastfeeding. Your healthcare professional will consider the infection’s severity, organ function, and concomitant medicines before prescribing.
Dosage and Usage
The usual regimen is taken by mouth twice daily, with or without food. Swallow tablets whole with a glass of water. If swallowing is difficult, ask your clinician about permitted administration options from the official label. Keep doses evenly spaced to maintain antiviral exposure. Do not change the schedule without your prescriber’s guidance.
Because maribavir affects certain drug transporters and enzymes, your transplant team may adjust monitoring for immunosuppressants. Always bring an updated medication list to clinic visits.
Strengths and Forms
The product is supplied as film-coated tablets containing 200 mg of maribavir. Packaging and availability may vary by market and lot; your pharmacist will dispense what is in stock per your prescription.
Missed Dose and Timing
If you miss a dose, take it when remembered unless it is close to your next scheduled time. In that case, skip the missed dose and resume your regular schedule. Do not take two doses at once. If vomiting occurs shortly after a dose, consult your prescriber for advice rather than repeating the dose automatically.
Storage and Travel Basics
Store tablets at room temperature in the original, tightly closed container. Keep the bottle dry and away from excess heat or direct light. Always keep medicine out of reach of children and pets. For travel, carry doses in hand luggage with a copy of your prescription and medication list. Pack extra days of therapy to cover delays. If crossing borders, keep the labeled pharmacy container for security checks and customs.
Benefits
This medicine offers an oral option for difficult-to-treat CMV after transplant. Tablets may be more convenient than intravenous therapies for many patients. The treatment can be used regardless of meal timing, which may help with adherence during recovery. Your team will monitor viral load and clinical response to gauge benefit.
Side Effects and Safety
Common side effects include taste disturbance, nausea, diarrhea, abdominal discomfort, and fatigue. Headache and vomiting can occur. Many effects are mild and manageable, but report bothersome symptoms to your prescriber. Serious risks are uncommon but can include significant elevations in liver tests or interactions leading to high levels of certain transplant medicines. Seek medical care for signs of severe allergic reaction, worsening infection, or unusual bleeding or bruising.
Drug Interactions and Cautions
Strong enzyme inducers such as rifampin, carbamazepine, phenytoin, phenobarbital, and St. John’s wort can reduce maribavir exposure and may compromise effectiveness. Combining with ganciclovir or valganciclovir is not recommended due to antagonism. This treatment can increase levels of calcineurin inhibitors and some other drugs; clinicians may adjust monitoring of tacrolimus or cyclosporine. Antifungals, certain antivirals, and anticonvulsants may also affect levels. Share a complete medication list, including over-the-counter products and herbal supplements.
For transplant background therapies, see Mycophenolic Acid and discuss coordination of care with your transplant team.
What to Expect Over Time
Your clinician will monitor CMV DNA levels and clinical signs. Some people notice taste changes early in treatment; these often lessen with time. Stomach-related effects may improve as your body adjusts. Consistent dosing is important for antiviral activity, so set reminders and pair doses with routine daily activities. Your prescriber will decide how long to continue therapy based on response, tolerability, and immune recovery, using the official label as guidance.
If your care team changes other medicines, such as antifungals or immunosuppressants, they may repeat blood tests to maintain safe levels. Ongoing communication with your transplant clinic supports safer, coordinated care.
Compare With Alternatives
Other options for CMV after transplant include valganciclovir or intravenous ganciclovir, foscarnet, and cidofovir. Choice depends on prior response, resistance patterns, kidney function, and tolerability. Valganciclovir is widely used but may be limited by bone marrow suppression. Foscarnet and cidofovir require intravenous administration and careful renal monitoring. Your specialist will tailor therapy to your infection and overall health.
To learn about antiviral classes more broadly, explore our article on Delstrigo Medication or see the Genvoya Guide for another antiviral context.
When comparing choices, consider regimen complexity, monitoring needs, potential side effects, and Maribavir tablets cost Canada in the context of your care plan.
Pricing and Access
Canadian pharmacy pricing can offer meaningful savings for US patients. You can check Livtencity cash price on our product page and discuss options with your clinician. We also list Maribavir price Canada so you can plan for therapy and follow-up laboratory monitoring. We provide clear checkout, with encrypted checkout to protect your information, and US delivery from Canada for eligible addresses.
If you are looking for periodic offers, visit our Promotions page for current notices. Final costs depend on quantity dispensed and prescriber directions. Our team confirms prescription details before fulfilment.
Availability and Substitutions
Availability can vary. If the product is temporarily out of stock, your prescriber may recommend an alternative antiviral or an interim plan based on your clinical status. Ask about Livtencity prescription price Canada when discussing timing and supply so your budget and care needs align. We do not quote restock dates; your pharmacist will advise on options if supply changes.
Patient Suitability and Cost-Saving Tips
This therapy may suit post-transplant patients who have refractory CMV, can take oral medication, and can attend regular monitoring visits. It may not be appropriate if severe drug interactions cannot be managed or if you have a known allergy to components of the tablet. People with significant kidney or liver impairment require individualized assessment.
- Multi-month fills: Ask your prescriber if a longer fill could reduce trips and coordination time.
- Aligned refills: Set reminders so you do not run out between clinic visits.
- Lab scheduling: Coordinate blood work with prescription refills to limit extra visits.
- Interaction check: Keep an updated medication list to minimize interaction risks.
- Budget planning: Discuss Maribavir cash price with your pharmacist before dispensing.
Questions to Ask Your Clinician
- Goal of therapy: How will we measure my response to this antiviral?
- Treatment length: What factors determine when to stop or change therapy?
- Interactions: Which of my medicines might raise or lower maribavir levels?
- Monitoring plan: How often will labs and CMV PCR testing be checked?
- Side-effect management: What should I do if taste changes or stomach issues occur?
- Safety considerations: Are there signs that mean I should contact the clinic urgently?
- Administration: Are there label-supported options if swallowing tablets is difficult?
Authoritative Sources
DailyMed: Livtencity (maribavir)
Health Canada Drug Product Database
Pricing and Ordering Help
Have your prescription ready, then place your order with YouDrugstore for prompt, express shipping and US delivery from Canada. This information is educational and not a substitute for your prescriber’s advice. Always follow the official label and your clinician’s instructions.
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Prices:
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How does maribavir work against CMV?
Maribavir inhibits the CMV UL97 protein kinase, an enzyme the virus needs for replication and viral particle maturation. By blocking this step, the drug can reduce viral activity and help control infection in people with reduced immune function after transplant. It is used for CMV disease that has not responded to other antiviral therapy. Your clinician will track viral load and clinical response to decide whether to continue treatment.
Can I crush or split the tablets?
Swallow tablets whole unless your prescriber reviews an alternative that is supported by the official label. Do not crush, split, or chew unless your clinician and pharmacist confirm an appropriate method. If you have difficulty swallowing, ask about label-based techniques or ancillary aids. Never change how you take medicine without professional guidance.
What foods or drinks interact with maribavir?
Food does not meaningfully affect absorption, so you can take doses with or without meals. Alcohol may worsen nausea or dizziness and is best avoided during periods of illness. The bigger issue is drug interactions with strong enzyme inducers or inhibitors. Share your full medication list, including supplements, so your care team can screen for interactions and adjust monitoring as needed.
How long will I need treatment?
Duration varies by viral load trends, symptoms, and immune recovery. Your transplant team will set goals and monitor response with lab tests and clinical checks. Therapy may continue until CMV is controlled and your clinician determines a safe stopping point. Because situations differ, your prescriber will use the official label and your individual progress to guide duration.
Is this antiviral safe in pregnancy or while breastfeeding?
There are limited data in pregnancy and lactation. Your clinician will weigh potential benefits against unknown risks and may consider alternative therapies. If you are pregnant, planning to become pregnant, or breastfeeding, discuss options before starting or continuing therapy. Do not begin, stop, or switch medicines without guidance from your prescriber.
What if I vomit after taking a dose?
If vomiting occurs soon after a dose, contact your transplant team or pharmacist for advice rather than repeating the dose on your own. They may consider timing, severity, and your overall plan before recommending the next step. Keep hydrated and note any other symptoms, such as fever or worsening stomach pain, that may require additional attention.
Will my insurance cover this treatment?
Coverage varies by plan and indication. Transplant antivirals are often reviewed under specialty benefits with prior authorization. Your clinic and pharmacy can help with documentation, such as proof of refractory CMV and recent laboratory results. If paying cash, ask about pricing and potential savings programs. We can provide a quote based on prescription details and quantity.
