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Reglan® Tablets for Gastroparesis and Nausea
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Metoclopramide is a prescription prokinetic and antiemetic medicine. It helps relieve nausea, vomiting, and symptoms of delayed stomach emptying. Refill through YouDrugstore with US delivery from Canada, and see options that work without insurance.
What Reglan Is and How It Works
Metoclopramide, also sold under the brand name Reglan®, increases movement in the upper digestive tract. It blocks dopamine receptors and enhances acetylcholine activity in the gut. This action helps the stomach empty more quickly and can reduce nausea. It may also improve reflux symptoms by tightening the lower esophageal sphincter.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
Many patients receive Metoclopramide tablets when symptoms are frequent around meals. Liquid options can help those who struggle with swallowing or need flexible dosing. This medicine crosses the blood-brain barrier, so central nervous system effects can occur.
Who It’s For
This treatment is used for adults with confirmed gastroparesis, often related to diabetes. It also helps prevent or treat nausea and vomiting in select settings, as directed by a prescriber. Some people take Reglan tablets for short courses after surgery or with certain therapies.
People with a history of tardive dyskinesia, uncontrolled epilepsy, pheochromocytoma, or gastrointestinal bleeding or obstruction should not use this therapy. Avoid use in Parkinson’s disease without specialist guidance. Discuss risks if you have depression, hypertension, or kidney or liver impairment.
Dosage and Usage
Follow your prescription label exactly. Doses are usually taken before meals and sometimes at bedtime. Swallow tablets with water and remain upright for a short period after taking them. For those using liquid, measure with a marked syringe or dosing spoon for accuracy.
Therapy for gastroparesis is typically short term. The boxed warning advises avoiding long-term use beyond 12 weeks unless the benefit outweighs the risk, as assessed by your clinician. If your plan includes Metoclopramide 10 mg before meals, use only as directed and report concerning side effects promptly.
Avoid alcohol and limit other sedating medicines while taking this treatment. If your regimen includes other gastric therapies, separate administration when advised by your prescriber to avoid absorption issues.
Strengths and Forms
Availability may vary by manufacturer and supply. Common options include oral tablets and an oral liquid.
- Tablets in 5 mg and 10 mg strengths
- Oral solution in standard concentrations for measured dosing
Generics and brands can differ in packaging and inactive ingredients, but active drug and labeled strength remain the same. Your prescription will determine the format dispensed.
Missed Dose and Timing
If you miss a dose, take it when remembered unless it is almost time for the next one. If it is close to the next scheduled dose, skip the missed dose and resume your regular schedule. Do not double up. Consistent timing with meals often helps symptom control and reduces stomach upset.
Storage and Travel Basics
Store tablets and liquid at room temperature in a dry place, away from heat and direct light. Keep the original, child-resistant container closed tightly. Do not freeze the liquid. For trips, pack your medicine in a carry-on, along with a copy of your prescription and your prescriber’s contact details. Use a clean dosing syringe for the liquid and rinse it after use. Keep out of reach of children and pets.
Benefits
This medicine can reduce feelings of fullness, bloating, and nausea associated with delayed gastric emptying. By improving stomach motility, it may help you tolerate meals better. For certain people, the liquid option offers flexible, measured doses when small adjustments are needed. Short treatment courses can support recovery in select postoperative or therapy-related scenarios when your clinician recommends it.
Side Effects and Safety
- Drowsiness or fatigue
- Restlessness or agitation
- Headache
- Diarrhea
- Insomnia
- Dizziness
Serious risks may include tardive dyskinesia (potentially irreversible, involuntary movements), neuroleptic malignant syndrome, depression or suicidal ideation, hypertension or fluid retention, and allergic reactions. The risk of movement disorders increases with higher dose and longer duration. Use the lowest effective dose for the shortest duration. Seek urgent care for high fever, muscle rigidity, severe confusion, rash, swelling, or breathing trouble.
Drug Interactions and Cautions
Dopamine agonists such as levodopa may be less effective when combined with this therapy. Antipsychotics can increase the risk of extrapyramidal symptoms. Combining with SSRIs or SNRIs may raise the risk of serotonin syndrome; monitor for agitation, sweating, or rapid heartbeat. CNS depressants, opioids, and alcohol can enhance sedation. Metoclopramide can alter absorption of some oral medicines, including digoxin and cyclosporine; your prescriber may adjust timing.
Tell your healthcare professional about all medicines, vitamins, and herbal products you take, including St. John’s wort. If you are pregnant, planning pregnancy, or breastfeeding, discuss the potential benefits and risks.
What to Expect Over Time
Many people notice improved tolerance of meals as the stomach empties more effectively. Nausea relief can vary based on the underlying cause and meal patterns. If symptoms persist or worsen, contact your prescriber to reassess the plan. Because this therapy carries movement-related risks with longer use, ongoing need should be reviewed regularly. Keeping a simple meal and symptom diary can help guide follow-up visits.
Compare With Alternatives
For motility support in select cases, Domperidone may be considered by some prescribers where permitted. For nausea control unrelated to motility, 5-HT3 blockers such as Ondansetron are commonly used. For reflux-dominant symptoms, acid suppression with proton pump inhibitors like Omeprazole, Pantoprazole, or Rabeprazole may be part of the plan your clinician sets.
Pricing and Access
See current options and compare Metoclopramide Canadian pricing with typical US cash-pay rates. Our checkout shows your Metoclopramide price before you submit your order. Savings vary by manufacturer and fill size. US shipping from Canada is available with prescription validation. If you use coupons, check our latest offers on Promotions. Checkout is protected with encrypted processing for your security.
Availability and Substitutions
Supply can vary by strength and format. If the exact item is unavailable, your prescriber may recommend a comparable alternative or a different form. When appropriate, generic options can support cost savings. You can also submit requests to Buy metoclopramide online and we will confirm stock and prescriber details before dispensing.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults with diagnosed gastroparesis who can avoid long-term use. It may not be appropriate for people with a history of movement disorders or those taking certain antipsychotics. Ask about multi-month fills if stable on therapy to reduce per-fill fees. Sign up for refill reminders to avoid gaps. If you are using other acid-control therapies, your clinician may align schedules to improve outcomes.
Questions to Ask Your Clinician
- Primary goal: symptom relief, meal tolerance, or both?
- Planned duration: how short can therapy be?
- Monitoring: what side effects should prompt a call?
- Combination plan: where do acid suppressants fit?
- Timing: how should doses relate to meals?
- Travel: what documentation should I carry?
Authoritative Sources
Health Canada Drug Product Database
Storage and Travel Links
Learn more about related conditions and therapies: Gastroparesis, Nausea And Vomiting, and our Gastrointestinal category. For acid control options, explore Esomeprazole or Dexilant. For reading on motility agents, see Domperidone Tablet. To compare PPI options, review Dexlansoprazole Uses.
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How long can I take metoclopramide safely?
Most adults use this medicine for the shortest possible time. Long-term use increases the risk of tardive dyskinesia, which can be permanent. Labels advise avoiding use beyond 12 weeks unless the potential benefit clearly outweighs the risk. Your prescriber will weigh your condition, response, and other medicines at each review. Never change the dose or duration without guidance from a healthcare professional.
What should I avoid while taking metoclopramide?
Avoid alcohol and use caution with other sedating medicines such as opioids, antihistamines, and sleep aids. Combining with antipsychotics can raise the risk of movement-related side effects. Tell your clinician about all medicines, vitamins, and herbal products you use. If you take dopamine agonists like levodopa, their effect may be reduced. Discuss driving or operating machinery until you know how this therapy affects you.
Does metoclopramide help with acid reflux?
This medicine can tighten the lower esophageal sphincter, which may reduce reflux, and it speeds stomach emptying. Many people also need acid suppression with a proton pump inhibitor or H2 blocker. Your clinician may consider options such as omeprazole or similar therapies alongside motility support. Treatment choices depend on your diagnosis and response.
Can I use metoclopramide during pregnancy or breastfeeding?
Use during pregnancy or while nursing requires a risk–benefit discussion. Some data suggest use in certain situations, but potential risks, including movement-related effects, must be considered. Your prescriber will evaluate your symptoms, alternatives, and timing. Do not start or continue the medicine without discussing your specific situation with a healthcare professional.
What are signs of serious side effects I should watch for?
Seek medical help for uncontrolled facial or limb movements, high fever, muscle stiffness, severe confusion, depressed mood or thoughts of self-harm, allergic swelling, or trouble breathing. These may indicate tardive dyskinesia, neuroleptic malignant syndrome, or hypersensitivity. While uncommon, prompt evaluation is important. Keep an updated list of medicines and report new symptoms quickly.
How should I measure the oral liquid?
Use a marked oral syringe or dosing spoon rather than kitchen teaspoons. Ask your pharmacist for a syringe that fits your dose. Shake the bottle if the instructions say so, and measure at eye level on a steady surface. Rinse the syringe with clean water after each use. Keep the bottle tightly closed and store it at room temperature away from moisture and light.
What if I’m still nauseated after starting treatment?
Contact your prescriber if symptoms persist or worsen. You may need an adjustment, a shorter course, or a different approach. Sometimes clinicians combine motility support with acid suppression or use a different antiemetic. Do not increase your dose on your own. Keep a brief record of meals, medicines, and symptoms to share; this helps guide the next steps.


