Mexitil® Capsules for Ventricular Arrhythmias

This oral antiarrhythmic treats dangerous ventricular rhythms. This page explains how it works, who it suits, and how to use it safely with US shipping from Canada. It also helps you compare options when buying Mexiletine without insurance.

What Mexitil Is and How It Works

Mexitil® is the originator brand of mexiletine, a class IB antiarrhythmic related to lidocaine. It blocks fast sodium channels in heart muscle, which can reduce abnormal automaticity and improve conduction during serious ventricular arrhythmias. Clinicians may use it to manage documented, life-threatening ventricular tachycardia, often alongside careful monitoring. As a prescription medicine, it should be started and adjusted only by a healthcare professional.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Ventricular Arrhythmia care often continues outside the hospital. Mexiletine capsules provide an oral option when longer-term rhythm control is needed. Taking it with food may improve stomach comfort. Your prescriber may coordinate ECGs and blood tests during treatment to check response and tolerability.

Who It’s For

This therapy is intended for adults with documented, serious ventricular arrhythmias. Some people receive it after stabilization on other agents. Mexiletine is not appropriate for minor or asymptomatic rhythm findings. It is also not a first-line choice for atrial arrhythmias.

People with cardiogenic shock, untreated second- or third-degree heart block, or severe liver impairment should avoid use unless carefully supported by a specialist. Discuss seizure history, hepatic disease, and any planned anesthesia. If you have a pacemaker or implantable defibrillator, your cardiology team will consider device settings when deciding on therapy.

For broader context on heart health, see Interesting Facts About Your Heart. You can also browse our Cardiovascular category for related treatments your clinician may consider.

Dosage and Usage

Follow your prescriber’s instructions on timing, frequency, and any adjustments. This medicine is usually taken two or three times daily. Swallow capsules with water. Taking doses with food or an antacid can help reduce heartburn, nausea, or stomach upset.

Try to take it at evenly spaced times. Avoid crushing or opening capsules unless your prescriber advises otherwise. If you start any new therapy, including over-the-counter medicines or supplements, inform your clinician. Your care team may schedule ECGs and lab work to guide ongoing dosing decisions.

Some individuals are sensitive to dose changes. If you notice tremor, unsteadiness, or vision issues, contact your prescriber. Do not make your own changes. For older adults, careful titration may be needed due to comorbidities or interacting therapies. For anticoagulant background information, you can read Eliquis Side Effects.

Strengths and Forms

In many markets, mexiletine is supplied as hard gelatin capsules in commonly available strengths such as 150 mg, 200 mg, and 250 mg. Availability can vary by manufacturer and jurisdiction. Your prescriber and pharmacist will match the strength to your individualized plan.

Some patients require dose adjustments based on response, side effects, or interacting medicines. If a particular strength is unavailable, your clinician may adjust the regimen using another strength to maintain the prescribed total daily amount.

Missed Dose and Timing

If you miss a dose, take it when you remember unless it is close to the next dose. If it is almost time for the next one, skip the missed dose and resume your regular schedule. Do not double up to catch up.

Keeping a dosing reminder on your phone or pillbox can help you stay consistent. If nausea or heartburn occurs, pairing doses with food often helps. When traveling across time zones, ask your prescriber how to adjust the schedule safely.

Storage and Travel Basics

Store capsules at room temperature, away from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. Do not store in a bathroom where humidity can be high.

When traveling, carry your medicine in its original labeled container. Pack it in your carry-on to reduce the risk of loss or temperature extremes. Bring a copy of your prescription and a medication list. If you use a weekly planner, refill it away from bright light and check dates regularly.

Benefits

This class can help reduce premature ventricular contractions and limit episodes of sustained ventricular tachycardia in selected patients. Being an oral option, it allows outpatient rhythm management without continuous IV access. It may also reduce emergency visits for some people when used as part of a broader care plan.

Because response varies, your prescriber will individualize therapy and monitoring. Consistent use and regular follow-up improve the chances of stable control and early detection of side effects.

Side Effects and Safety

• Stomach upset or heartburn
• Nausea or vomiting
• Dizziness or lightheadedness
• Tremor or shakiness
• Unsteady gait or coordination problems
• Numbness or tingling
• Blurred vision
• Headache or fatigue

Serious but less common risks include worsening arrhythmia, chest pain, fainting, new neurological symptoms, liver problems, and blood count changes. Seek urgent care for severe dizziness, palpitations with fainting, or chest discomfort. Contact your clinician promptly for yellowing skin or eyes, dark urine, fevers, unusual bruising, or persistent vomiting.

Drug Interactions and Cautions

Many medicines can affect levels or effects. CYP1A2 or CYP2D6 inhibitors may raise exposure, while enzyme inducers can lower it. Examples include certain antidepressants, anti-seizure medicines, and antibiotics. Antacids with aluminum or magnesium may reduce absorption. Stimulants can increase heart rate or blood pressure and warrant caution.

Discuss all therapies with your prescriber, including theophylline, which can interact with mexiletine. Blood thinners may require closer observation; for background, see Warfarin. Some calcium channel blockers can modify heart conduction; read about Verapamil for context. Liver disease, seizure disorders, and electrolyte imbalances also require care.

What to Expect Over Time

Your cardiologist may start at a cautious dose and reassess with ECGs, symptoms, and lab tests. Some individuals notice fewer palpitations or a steadier rhythm as the plan settles. Others require adjustments or a different therapy. Keep a symptom diary, and bring it to visits. Good hydration and consistent sleep may support overall cardiac stability.

Long-term plans often include periodic reviews of liver function and a check of other medicines for new interactions. If your condition changes, your prescriber may adjust timing or consider alternative agents.

Compare With Alternatives

Several approved antiarrhythmics are used for ventricular arrhythmias. Your prescriber will weigh benefits and risks for your situation.

• Amiodarone: Broad-spectrum antiarrhythmic. Often used when other options are inadequate or not tolerated.
• Sotalol: Has beta-blocking and class III effects. Requires careful QT monitoring and dose adjustments by kidney function.

Device therapy and ablation may be considered depending on your history. Decisions are individualized by your cardiology team.

Pricing and Access

We offer Canadian pricing with convenient US shipping from Canada. To see current Mexiletine price and supply options, check the product page and sign in for details. Availability can vary by manufacturer and quantity.

You can Order Mexiletine online with a valid prescription. If you are comparing discounts, see our Promotions page for current offers. Checkout is secure and encrypted. Your prescriber’s directions always guide what we dispense.

Availability and Substitutions

Supply can fluctuate. If the exact strength or pack size you use is unavailable, your prescriber may recommend an equivalent schedule or a different therapy. If Mexiletine cost is a concern, discuss dose consolidations, fewer refills, or alternative agents that meet your clinical needs.

We cannot guarantee dates for restock. Your clinician or pharmacist can help with practical substitutions that maintain the intended daily amount.

Patient Suitability and Cost-Saving Tips

This medicine suits adults with documented, serious ventricular arrhythmias who can attend regular monitoring. It may not suit people with severe conduction disease without a pacemaker, active cardiogenic shock, or severe liver disease. Tell your prescriber about seizure history and any unusual neurologic symptoms.

To reduce costs, ask about 60- to 90-day fills if stable. Set refill reminders so you do not run out. Use generic products when appropriate. Look for a Mexiletine coupon during seasonal campaigns, and compare quantities to find the best overall value for your plan.

Questions to Ask Your Clinician

• Primary goal: What rhythm problem are we targeting?
• Monitoring plan: How often will ECGs and labs be checked?
• Side effects: Which symptoms should prompt a call?
• Interactions: Which medicines or supplements should I avoid?
• Food and timing: Should I always take it with meals?
• Travel: How should I handle time zone changes?

Authoritative Sources

FDA DailyMed: Mexiletine HCl Capsules

Health Canada Drug Product Database

US Prescribing Information (PDF)

Ready to proceed? Place your order with express US shipping from Canada. Prescription required; temperature-controlled handling when required. This information is educational and does not replace your clinician’s advice.