Nexavar® Tablets for Liver, Kidney, and Thyroid Cancer

This medicine is a prescription tablet used in certain liver, kidney, and thyroid cancers. This page explains how it works, typical use, and access options with US shipping from Canada. We also outline Nexavar price without insurance to help you plan.

What Nexavar Is and How It Works

Nexavar® (sorafenib) is a multikinase inhibitor. It targets proteins that drive tumor growth and blood vessel formation, including RAF kinases, VEGFR, PDGFR, FLT3, RET, and KIT. By blocking these pathways, the treatment may slow cancer cell proliferation and reduce tumor blood supply. It is approved for advanced renal cell carcinoma, unresectable hepatocellular carcinoma, and certain differentiated thyroid cancers that no longer respond to radioactive iodine.

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Therapy is taken by mouth, which can simplify care compared with clinic-based infusions. Your healthcare professional will decide if sorafenib fits your treatment plan and will monitor your blood pressure, liver tests, skin, and overall tolerance over time. Learn more about the conditions it treats in our resources on Liver Cancer and Thyroid Cancer.

Who It’s For

This medicine is used in adults with advanced kidney cancer, unresectable primary liver cancer, or progressive, differentiated thyroid cancer refractory to radioactive iodine. People with severe allergies to any component should not take it. Those with recent heart problems, uncontrolled blood pressure, significant bleeding risk, poor wound healing, or serious liver impairment may require careful assessment.

It may cause fetal harm. Discuss effective contraception and pregnancy plans with your prescriber. Breastfeeding is not recommended during treatment. Share your full medication list, including supplements and herbals.

Dosage and Usage

Use exactly as prescribed on your label. The standard schedule is twice daily dosing, swallowed with water. Take doses at least one hour before or two hours after meals to support consistent absorption. Continue until your prescriber advises otherwise. Do not crush or split tablets. If side effects occur, your prescriber may adjust your plan; follow the official label or clinic instructions.

General tips:

• Swallow tablets whole with water
• Aim for consistent timing morning and evening
• Record doses and symptoms in a treatment diary
• Monitor blood pressure regularly as advised

When uncertain, defer to the FDA label or your oncology team for direction.

Strengths and Forms

Film-coated tablets are supplied in one strength: 200 mg. Pack sizes and manufacturers can vary by market and supply.

Missed Dose and Timing

If you miss a dose, take it when you remember unless it is close to the next one. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double up. If you vomit after taking a dose, do not retake it; go back to your normal time.

Storage and Travel Basics

Store tablets at room temperature in the original container with the lid tightly closed. Keep them dry, away from bathroom humidity, and out of reach of children and pets. Do not use tablets that are broken or damaged. When traveling, carry your prescription in your hand luggage, keep the label visible, and bring a copy of your prescription and clinic contact information. If time zones change dosing windows, ask your prescriber for a simple schedule to avoid confusion.

Benefits

This therapy targets multiple cancer pathways, which may help slow tumor growth in approved settings. It is taken by mouth, avoiding infusion visits. Your team can tailor monitoring to your needs, focusing on blood pressure, skin care, and tolerance. Because it is used across several cancers, clinicians may apply it within broader treatment sequences.

Side Effects and Safety

• Common: diarrhea, rash, hand-foot skin reaction, fatigue, high blood pressure
• Other: nausea, decreased appetite, weight loss, hair thinning, dry skin

Serious but less common risks include heart problems such as ischemia, severe bleeding, liver injury, gastrointestinal perforation, severe skin reactions, reversible posterior leukoencephalopathy syndrome, and impaired wound healing. Seek urgent care for chest pain, severe bleeding, sudden shortness of breath, yellowing skin or eyes, or severe headache. Report persistent diarrhea, painful skin on hands or feet, or marked blood pressure increases to your oncology office.

Drug Interactions and Cautions

Strong enzyme inducers may lower sorafenib exposure, while certain inhibitors can change levels. Tell your prescriber about antibiotics, antifungals, seizure medicines, HIV therapies, and any herbal products such as St. John’s wort. Warfarin and other anticoagulants may increase bleeding risk and require closer monitoring. Be cautious with QT-prolonging medicines and blood pressure drugs; your clinician may adjust your plan. Avoid new supplements unless cleared by your care team.

What to Expect Over Time

Clinicians typically reassess symptoms, blood pressure, and labs at regular intervals. Skin reactions and gastrointestinal effects may appear early and can often be managed with supportive care and schedule guidance. Energy levels may vary. Keep a simple log of daily doses and side effects to share at visits. Many people find phone reminders, a pill organizer, and a consistent dosing routine helpful over weeks and months.

Compare With Alternatives

Several oral kinase inhibitors are used in similar settings. Cabozantinib may be considered after or instead of sorafenib in certain scenarios; see Cabometyx® for details. Another option for specific liver cancer sequences is Stivarga® regorafenib, which is used after disease progression on prior therapy. Your clinician will select and sequence therapies based on your cancer type, prior treatments, and tolerance.

Pricing and Access

We support transparent Canadian options that include US fulfilment. If you want a snapshot of Nexavar price, check the product page for current figures and cash-pay context. You can also compare Generic sorafenib price where available. Ships from Canada to US applies for eligible orders with a valid prescription. For occasional offers, see our Promotions page. Prescription required and verified.

Availability and Substitutions

Supply can vary by strength, manufacturer, and market demand. If your item is temporarily unavailable, your prescriber may recommend an alternative in the same class or a different line of therapy. If you have questions about Sorafenib tablets cost, ask our team before your prescriber sends the script so we can guide options that match your plan.

Patient Suitability and Cost-Saving Tips

Good candidates can swallow tablets, follow fasting guidance, and attend regular monitoring. People with uncontrolled blood pressure, recent major surgery, or high bleeding risk may need a different plan. To help manage the Nexavar cash price, ask your prescriber about multi-month fills when appropriate. Consider coordinating refills a week before your supply runs low. Keep your prescriber informed about any financial barriers; they may streamline authorizations or recommend alternatives.

For broader education on treatment landscapes, explore our article Common Types Of Cancer. For related targeted therapies, see Cancer and learn more about similar agents in Inlyta Uses and Cabometyx Uses.

Questions to Ask Your Clinician

• Food and dosing: How should I time doses around meals?
• Monitoring: Which lab tests and blood pressure checks will I need?
• Skin care: What steps help with hand-foot skin reaction?
• Surgery: When should I pause therapy around planned procedures?
• Interactions: Which medicines or supplements should I avoid?
• Family planning: What contraception is recommended during and after treatment?

Authoritative Sources

FDA Prescribing InformationDailyMed SorafenibHealth Canada DPD

Ready to proceed? Order Nexavar online with prompt, express shipping and US delivery from Canada, with temperature-controlled handling when required. This information is not a substitute for medical advice; always follow your prescriber’s guidance and the official label.