Nifedipine Extended-Release Tablets for Hypertension and Angina

What Nifedipine Is and How It Works

Nifedipine is a calcium channel blocker used to lower blood pressure and help prevent angina. It relaxes blood vessel walls, which reduces vascular resistance and improves blood flow. This page explains how the treatment works and how to use it safely with US delivery from Canada. Many people compare options for Nifedipine without insurance to manage out-of-pocket costs.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This medicine decreases the movement of calcium into smooth muscle cells in the heart and arteries. That effect helps the heart do less work against pressure. It can also reduce the frequency of chest pain episodes in stable angina.

Who It’s For

This therapy is used for adults with high blood pressure and for the prevention of chronic stable angina. It may be part of a single-agent plan or combined with other agents when advised by a prescriber. People with very low blood pressure, certain heart conduction issues, or recent severe cardiac events should discuss risks with a clinician before starting. For related conditions, see our Hypertension and Angina guides, and learn practical steps in Treat Hypertension Tips.

Dosage and Usage

Extended-release tablets are typically taken once daily. Swallow whole with water. Do not crush, split, or chew the tablet. Take at the same time each day. You can take it with or without food, but stay consistent with how you take it. Avoid grapefruit and grapefruit juice because they may change drug levels.

If your prescriber also uses other blood pressure medicines, rise slowly from sitting or lying positions to reduce dizziness. Do not use immediate-release forms for rapid blood pressure control unless specifically directed in an acute setting. Follow your clinician’s advice and the official label for your exact schedule.

Strengths and Forms

This medicine is available as once-daily extended-release tablets. Availability can vary by supplier and jurisdiction. Commonly prescribed strengths include Nifedipine ER 60 mg in an extended-release format. Your prescriber will choose a strength based on your response and overall plan.

Missed Dose and Timing

If you miss a dose, take it when you remember on the same day. If it is close to your next scheduled dose, skip the missed dose and return to your regular timing. Do not double up to make up for a missed tablet. Keeping a daily reminder can help you stay on track.

Storage and Travel Basics

Store tablets at room temperature in a dry place and keep the bottle tightly closed. Protect from moisture and excess heat. Keep out of reach of children and pets. When you travel, carry your medication in your hand luggage along with a copy of your prescription. Use the original labeled container for security checks. If you cross time zones, maintain your once-daily rhythm by spacing doses roughly 24 hours apart. If unsure, ask your healthcare professional for timing guidance before your trip.

Benefits

Calcium channel blockers can help lower blood pressure and reduce angina episodes. Once-daily extended-release tablets support steady control over the day. Generic availability may provide meaningful savings compared with some brand alternatives. For broader heart-health options, browse our Cardiovascular category.

Side Effects and Safety

• Headache, flushing
• Dizziness or lightheadedness
• Ankle or leg swelling
• Fatigue
• Nausea or heartburn

Some people may experience low blood pressure, worsening angina at start, or fast heartbeat. Swelling can occur and is usually dose related. Rare effects include gum overgrowth or severe skin reactions. Seek urgent care for severe chest pain, fainting, or signs of an allergic reaction. If you also take other pressure-lowering agents, you may feel more lightheaded at first. Report persistent or severe effects to your prescriber.

Drug Interactions and Cautions

Avoid grapefruit. Strong CYP3A4 inhibitors (such as certain azole antifungals, macrolide antibiotics, or protease inhibitors) can raise levels. Inducers like rifampin or some seizure medicines can reduce exposure. St. John’s wort may lower effectiveness. Use caution if you have significant liver problems. Discuss your full medication list, including over-the-counter products and supplements, with a healthcare professional. If you are pregnant, planning pregnancy, or breastfeeding, ask your prescriber about potential benefits and risks.

What to Expect Over Time

Blood pressure may trend downward with consistent daily use. Angina episodes can become less frequent in stable disease. Dizziness and flushing often lessen as your body adjusts. Keep taking your tablets even when you feel well, unless your clinician advises otherwise. Track home readings if recommended and bring your log to appointments. For added background on pressure control strategies, see Manage Hypertension.

Compare With Alternatives

Amlodipine is another dihydropyridine calcium channel blocker used once daily for high blood pressure and angina prevention. Some people may switch within the class based on side effects or formulary access. Compare features with Amlodipine. Branded long-acting nifedipine is also available; see how the brand formulation lines up with generics at Adalat XL. Your prescriber will guide any switch.

Pricing and Access

See live updates for Nifedipine price on this page. You can compare Canadian pricing and ask your clinician about 90-day supplies to reduce refill trips. We offer transparent checkout and encrypted payment processing. US listings are eligible for Ships from Canada to US. If you watch for seasonal deals, check our Promotions page for current offers.

Availability and Substitutions

Availability can vary by strength and manufacturer. A valid Nifedipine prescription from your prescriber is required for dispensing. If a specific brand or size is not in stock, your clinician may recommend an equivalent formulation in the same class. We cannot provide restock dates, but we can help you review alternatives your prescriber approves.

Patient Suitability and Cost-Saving Tips

This therapy may be suitable for adults diagnosed with high blood pressure or stable angina who need a once-daily option. It may not be appropriate for people with severe aortic stenosis, very low baseline pressure, or specific heart rhythm issues. Share your full medical history with your clinician to ensure safe selection.

To manage costs, ask your prescriber about larger fills if appropriate, which can reduce per-tablet expenses. Set refill reminders before you run low. Compare pharmacy quotes for the Nifedipine cash price with your plan copay to decide how you want to pay. Keep one pharmacy when possible to help monitor interactions.

Questions to Ask Your Clinician

• Starting plan: goals and monitoring
• Timing: morning vs evening use
• Food interactions: grapefruit avoidance
• Combination therapy: added agents and risks
• Side effects: what to watch
• Travel: timing across time zones

Authoritative Sources

FDA DailyMed: Nifedipine Extended-Release

Health Canada DPD: Adalat XL Product Information

Manufacturer: Adalat Information (Bayer)

Ready to proceed? You can place your request with prompt, express, US shipping from Canada. Orders include secure processing and temperature-controlled handling when required. This information is educational and not a substitute for your clinician’s advice.