Repaglinide Price and Online Availability for Type 2 Diabetes

What Repaglinide Is and How It Works

Repaglinide is an oral diabetes medicine in the meglitinide class. It helps lower post-meal blood sugar in adults with type 2 diabetes. Tablets come in 0.5 mg, 1 mg, and 2 mg strengths. This page covers repaglinide uses, dosing, safety, and repaglinide price so you can plan care with your prescriber.

As a short-acting insulin secretagogue, repaglinide prompts the pancreas to release insulin in response to meals. It acts quickly and wears off within hours, which supports flexible meal timing while targeting after-meal spikes. Typical use is before each main meal, alongside diet and exercise. It is not for type 1 diabetes or diabetic ketoacidosis.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba and meeting Canadian pharmacy standards. We coordinate fulfillment through vetted partner pharmacies, and prescriptions are reviewed by licensed pharmacists before shipment. We offer brand and generic medicines at Canadian prices and also carry OTC health products, with US shipping available.

To support safe access, we source through licensed and vetted international partner pharmacies so you receive authentic brands and a broad selection at affordable pricing.

Dosage and Usage

Repaglinide dosing is individualized based on blood glucose, A1C, and meal patterns. Tablets are usually taken two to four times daily before meals.

• Starting dose: 0.5 mg before each main meal for most patients not previously on hypoglycemics. Some may start at 1 mg if A1C is closer to target.
• Titration: Adjust at weekly intervals based on glucose readings. Dose per meal may range from 0.5 mg to 4 mg, with a typical daily maximum of 16 mg.
• When to take: Administer 0 to 30 minutes before eating. If a meal is skipped, skip that dose.
• Missed dose: If you forget and the meal has passed, wait until the next meal. Do not double up to make up for a missed dose.

Repaglinide can be used alone or combined with other agents such as metformin or a thiazolidinedione. Monitor for hypoglycemia, especially when used with other glucose-lowering drugs.

• Storage: Store your tablets at room temperature (15-30 C), dry, away from heat and light. Keep in the original container and out of children’s reach.
• Travel: Carry your medication in hand luggage. Bring extra doses, a copy of your prescription, and glucose tablets or a quick sugar source.
• Monitoring: Track fasting and post-meal glucose as directed by your clinician. Record values when doses are adjusted.

Drug interactions can be significant. Gemfibrozil is contraindicated with repaglinide. Strong CYP2C8 or CYP3A4 inhibitors (for example, clarithromycin, azole antifungals) can increase exposure. Clopidogrel can raise levels. Discuss all medicines and supplements with your prescriber to avoid low blood sugar or other issues.

Benefits and Savings

Repaglinide targets postprandial glucose, which supports overall A1C reduction. Its short action fits varied meal times and may suit patients who cannot tolerate metformin or need add-on therapy. Tablet strengths allow fine dose adjustments meal by meal.

Ordering from YouDrugstore is simple online (and by phone where available), with friendly customer-service chat during posted office hours. Customers often save 60-80% versus typical US prices. Multi-month supplies can lower the per-month cost, and we can send reorder reminders so you do not run short.

Side Effects and Safety

• Common: Hypoglycemia (shakiness, sweating, dizziness), headache, nausea, diarrhea, upper respiratory symptoms, joint or back pain.
• Less common: Weight gain, sinusitis, visual changes during glucose shifts, mild liver enzyme elevations.
• Serious: Severe hypoglycemia, allergic reactions, hepatic dysfunction. Seek urgent care for confusion, loss of consciousness, or persistent vomiting.

Risk factors for low blood sugar include missed meals, heavy exercise without carbohydrate intake, overdose, alcohol, or interacting medicines. Elderly patients and those with hepatic impairment may need lower doses and closer monitoring. Repaglinide is not recommended in type 1 diabetes or during episodes of diabetic ketoacidosis. Use in pregnancy or breastfeeding only if the potential benefit justifies the potential risk, as guided by your clinician.

Key interactions: Avoid gemfibrozil. Use caution with clopidogrel, trimethoprim, cyclosporine, clarithromycin, azole antifungals, rifampin, and other potent CYP modulators. If insulin or sulfonylureas are added, reassess hypoglycemia risk and adjust doses accordingly.

Onset Time

Repaglinide begins to work quickly. Blood levels peak about one hour after dosing. Glucose-lowering starts within 30 minutes and mainly covers the next 4 to 6 hours. This swift, short action is why it is taken right before meals and skipped if the meal is skipped.

Compare With Alternatives

Repaglinide (brand Prandin) is a meglitinide, distinct from sulfonylureas like glipizide, which have longer action and higher risk of prolonged hypoglycemia. Repaglinide’s flexibility can benefit people with irregular meal schedules.

DPP-4 inhibitors (for example, sitagliptin) carry a low hypoglycemia risk when used alone but may be less potent for post-meal spikes. GLP-1 receptor agonists can reduce weight and improve glycemia, but they are injectables and may cost more.

When oral options are not enough, prandial insulin is an alternative. Rapid-acting analogs are dosed with meals; see apidra vials for an example. Some patients use premixed insulin to cover basal and bolus needs; see novolin ge 30 70 vial for a human insulin premix option. Choice depends on A1C goals, cost, and tolerance.

Combination Therapy

Repaglinide is often combined with metformin to address both fasting and postprandial glucose. It can also be paired with a thiazolidinedione in selected cases. If basal insulin is added, monitor for hypoglycemia and adjust doses. Do not combine with another insulin secretagogue unless your prescriber provides a clear plan.

Patient Suitability and Cost-Saving Tips

Repaglinide suits adults with type 2 diabetes who need better post-meal control and prefer oral therapy. It is not for type 1 diabetes, hyperglycemia due to ketoacidosis, or patients unable to detect hypoglycemia. Liver impairment warrants careful dosing. Those with frequent missed meals may need a different plan.

To reduce your repaglinide cost, consider generic tablets (0.5 mg, 1 mg, 2 mg), choose a multi-month supply when appropriate, and watch for bulk pricing. For current offers and bulk options, see our repaglinide discount page. Reorder reminders help you avoid urgent, small shipments that raise per-tablet costs.

If weight management is also a goal, discuss separate options for that purpose. For background on injectable choices used for weight loss, read best weight loss injections top options to consider. That discussion is not a substitute for medical advice and does not apply to repaglinide dosing.

Authoritative Sources

Review the official labeling and monographs before starting therapy. See the FDA Prescribing Information for repaglinide, the Health Canada Drug Product Database, and the manufacturer’s page for Prandin (repaglinide).

Ready to order? YouDrugstore coordinates with licensed partner pharmacies to ship directly to you in the US with prompt, express shipping. Our customer-service team is available during posted office hours to help with ordering or product questions.

This information is educational and not a substitute for professional medical advice. Always follow your prescriber’s directions, local laws, and the patient leaflet that comes with your medication.