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ReVia® Tablets for Alcohol Use Disorder
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ReVia® is a brand of naltrexone tablets used as part of treatment programs for alcohol and opioid dependence. This page explains how the medicine works, who it suits, and how to use it safely. Ships from Canada to US for patients who pay without insurance.
What ReVia Is and How It Works
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
Naltrexone is an opioid receptor antagonist. It binds to mu-opioid receptors and blocks the euphoric effects of opioids. In alcohol use disorder, it can reduce reward responses linked to drinking. This helps patients stay engaged in counseling and structured support. Treatment is used together with psychosocial therapy; it is not a stand-alone cure.
People must be opioid-free before starting. Beginning therapy while physically dependent on opioids can trigger acute withdrawal. Clinicians often confirm opioid abstinence with history, urine testing, or a naloxone challenge when appropriate. This medicine may also lower tolerance to opioids; relapse to prior doses after stopping can increase overdose risk.
Who It’s For
Naltrexone is indicated as part of a comprehensive plan for adults with alcohol use disorder. It is also used to maintain abstinence in individuals with opioid use disorder who have completed detoxification. Behavioral therapy, mutual-help groups, and ongoing follow-up remain essential components of care. See our category pages for background on Alcohol Use Disorder and Opioid Use Disorder.
Do not use this treatment if currently taking opioids, if withdrawal is expected, or if there is acute hepatitis or liver failure. Patients with liver disease, kidney impairment, or a history of depression should discuss risks with a healthcare professional. Use in pregnancy or while breastfeeding requires prescriber guidance based on potential benefits and risks.
Dosage and Usage
Standard labeling supports once-daily dosing. Many adults start with Naltrexone 50 mg each day. Some programs use supervised dosing schedules based on clinic protocols. Follow the directions from the prescriber and the patient information leaflet for the specific regimen.
Swallow tablets with water. Take with food if nausea occurs. Keep regular dosing times to support adherence. Counseling, relapse-prevention strategies, and monitoring by a clinician are integral to success. Do not attempt to overcome opioid blockade with higher opioid doses; this can be dangerous.
Strengths and Forms
Tablets are commonly supplied in one strength. Availability may vary by manufacturer and country.
- Tablets: 50 mg
Brand and generic presentations may differ in packaging. Pharmacists may source equivalent products approved by national regulators.
Missed Dose and Timing
If a dose is missed, take it when remembered the same day. If it is almost time for the next dose, skip the missed dose. Do not double up. Maintain consistent daily use alongside counseling and support services. If multiple doses are missed, contact the prescriber for guidance.
Storage and Travel Basics
Store tablets at room temperature in a dry place. Keep the bottle tightly closed and away from moisture. Protect from excessive heat and direct light. Keep out of reach of children and pets.
When traveling, carry the original labeled container in hand luggage. Pack only what you need plus a small buffer, and bring your prescription and clinic contact details. If crossing borders, a copy of the prescription and a medication list can help with screening questions. For home storage and travel, keep your medicine secure and avoid pill organizers if small children are present.
Benefits
This therapy blocks opioid effects and can reduce alcohol-related reward, which helps patients maintain abstinence or cut down drinking within structured programs. It has oral dosing and is non-addictive. The class can be used long term when tolerated, with periodic reassessment by the prescriber. ReVia tablets offer a familiar daily routine that fits into counseling and recovery plans.
Side Effects and Safety
- Nausea or stomach upset
- Headache
- Dizziness or tiredness
- Sleep changes
- Anxiety or restlessness
- Joint or muscle aches
Serious effects are uncommon but can include liver-related problems such as abdominal pain, dark urine, or yellowing of skin or eyes. Mood changes, including depression, can occur. Stop therapy and seek medical help if severe symptoms appear. After treatment, opioid sensitivity may increase; previously tolerated doses can cause overdose. For opioid emergencies, community programs may supply rescue devices such as Narcan® Nasal Spray.
Drug Interactions and Cautions
Do not use with opioid pain medicines, opioid cough syrups, or opioid antidiarrheals. Inform dentists and surgeons about naltrexone use before procedures. If opioid analgesia is required for acute pain, special supervision in a medical setting is recommended. Discuss use with other hepatotoxic agents, including some TB drugs or high-dose acetaminophen. Alcohol counseling and ongoing monitoring are important for those with past liver disease. See additional mental health resources under Mental Health.
What to Expect Over Time
Many patients find cravings easier to manage when therapy is combined with counseling. Benefits are tied to consistent use and strong psychosocial support. Clinicians may track alcohol use, withdrawal symptoms, and mood. The plan is reassessed regularly. If tolerability issues develop, prescribers may adjust timing or consider alternatives according to labeling.
Engagement with therapy, adherence tools, and scheduled follow-ups improve outcomes. Pill organizers, reminder apps, and supervised dosing can help when permitted by the care plan. Support groups and family involvement further encourage long-term progress.
Compare With Alternatives
Generic naltrexone offers the same active ingredient as branded tablets and may be a cost-conscious choice. See Naltrexone HCl for available presentations. Another FDA- and Health Canada–approved option for alcohol use disorder is acamprosate. It supports abstinence maintenance and is dosed three times daily. Learn more about Campral® and discuss suitability with a prescriber. For educational reading on alcohol and medications, you may find this article helpful: Alcohol Risks.
Pricing and Access
Canadian pharmacy purchasing can reduce out-of-pocket spend for many patients. The Cost of ReVia varies by supplier and pack size. Check the product page for current pricing and availability. US shipping from Canada is available with a valid prescription. If comparing generic options, review the active ingredient and manufacturer details listed on each product page.
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Availability and Substitutions
Supply can differ by manufacturer and market. Pharmacists may dispense an equivalent naltrexone product approved by Health Canada if the branded pack is not available. Naltrexone from Canada follows national quality standards. If the brand is out of stock, a prescriber may recommend a suitable alternative based on the treatment plan. This process is prescription required and verified.
Patient Suitability and Cost-Saving Tips
Patients committed to recovery programs and opioid-free at initiation tend to be appropriate candidates. Those with active opioid use, acute hepatitis, or liver failure should avoid this therapy. Clinicians may check baseline liver enzymes and review all current medicines.
- Multi-month fills: reduce refills and often lower per-tablet costs
- Set reminders: support steady daily use
- Generic options: compare approved naltrexone equivalents
- Program support: pair medication with counseling for best results
- Travel prep: carry labeled bottles and prescriptions
Patients under structured care may use supervised dosing if adherence is challenging. Regular visits help monitor liver health, mood, and any side effects. For broader context on recovery, browse our category resources for Alcohol Use Disorder and Opioid Use Disorder.
Questions to Ask Your Clinician
- Am I opioid-free long enough to start this therapy?
- How will this medicine fit with my counseling plan?
- What liver tests or follow-ups are recommended?
- What should I do if I need pain control after an injury?
- Which warning signs mean I should stop and call the clinic?
- Could an alternative like acamprosate be a better fit for me?
Authoritative Sources
FDA DailyMed: Naltrexone Hydrochloride Tablets
Health Canada Drug Product Database
FDA Prescribing Information: Naltrexone
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Can patients drink alcohol while taking naltrexone?
Naltrexone does not cause illness when alcohol is consumed, unlike disulfiram. It may reduce reward from drinking, which can support abstinence or reduction within a structured program. Many clinicians recommend avoiding alcohol entirely, especially early in treatment. Counseling and monitoring remain essential. Follow the plan set by the healthcare professional and the program providing support.
How long should treatment continue?
Duration varies by individual response, goals, and tolerability. Some patients use naltrexone for several months as part of a comprehensive plan, while others may continue longer with periodic reassessment. Clinicians review benefits, side effects, and lab results over time. Do not stop suddenly without consulting the prescriber, especially if there are concerns about relapse risk or mood changes.
What liver tests are recommended with this medicine?
Prescribers commonly check baseline liver enzymes before starting. Periodic monitoring may follow, especially when there is a history of liver disease or concurrent hepatotoxic medicines. Patients should report symptoms like abdominal pain, dark urine, or yellowing of the skin or eyes. The clinician will decide on lab frequency based on overall risk and clinical judgment.
Can this be started if someone recently used opioids?
No. Starting naltrexone while physically dependent on opioids can precipitate acute withdrawal. Clinicians typically confirm opioid abstinence before initiation, sometimes using urine tests or a naloxone challenge. Patients should disclose all opioid prescriptions, recent use, and any illicit exposure. If acute pain requires opioid treatment later, it should be managed in a monitored setting.
Is there a difference between brand and generic naltrexone?
Brand and generic tablets contain the same active ingredient and are required to meet regulatory standards for quality and bioequivalence. Inactive ingredients and packaging can differ. Patients who switch between products should inform the prescriber and pharmacist if any new side effects occur. Coverage and costs may vary; pharmacists can discuss approved options available through the pharmacy.
What happens if a dose is vomited?
If vomiting occurs shortly after a dose, clinicians may advise whether to retake based on timing and symptoms. Many will suggest waiting until the next scheduled dose if it is uncertain how much was absorbed. Persistent vomiting, severe nausea, or signs of liver issues warrant medical evaluation. Follow the patient information leaflet and contact the prescriber for individualized instructions.
Where can I learn more about alcohol risks with medicines?
Educational resources can help patients understand interactions between alcohol and prescription therapies. See our article on alcohol and psychotropic medicines for practical tips. For broader context on condition management, review our category pages on alcohol and opioid use disorders. Always rely on guidance from a healthcare professional for personal decisions.
