Crestor® Tablets for High Cholesterol

Rosuvastatin calcium is a statin used to lower LDL cholesterol. It helps reduce cardiovascular risk when diet and exercise are not enough. We make it simple to access this treatment with US delivery from Canada, even if you are paying without insurance.

What Crestor Is and How It Works

Crestor® contains rosuvastatin, a statin that slows cholesterol production in the liver. It blocks HMG-CoA reductase, which lowers LDL and non-HDL cholesterol and can modestly raise HDL. It also reduces triglycerides. These changes help reduce the risk of cardiovascular events when part of a broader plan that includes diet and exercise.

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Rosuvastatin can be used for primary hyperlipidemia, mixed dyslipidemia, and to lower the chance of heart attack or stroke in select adults. It is often chosen when stronger LDL reduction is needed. This medicine may be used alone or with other lipid-lowering therapies.

To learn more about the condition it treats, see our overview of High Cholesterol and information on inherited forms like Familial Hypercholesterolemia.

Who It’s For

This treatment is for adults with high cholesterol, mixed dyslipidemia, or who have certain risk factors for cardiovascular disease. It may also be used for some patients with familial hypercholesterolemia when additional LDL reduction is needed.

Avoid this medicine during pregnancy or while breastfeeding. Do not use it if you have active liver disease, unexplained persistent liver enzyme elevations, or a known allergy to any component. People with a history of muscle disorders, kidney problems, or heavy alcohol use should discuss risks with a clinician.

Dosage and Usage

Take rosuvastatin once daily at the same time each day. You can take it with or without food. Swallow tablets whole with water. If your clinician gives you a specific schedule, follow those directions.

Typical starting doses are guided by baseline LDL, goals, and overall risk. Some patients start low and increase as tolerated. Others who need larger LDL reductions may start higher. The maximum dose is reserved for select patients who require aggressive LDL lowering and are at low risk for muscle side effects.

Separate doses from aluminum or magnesium antacids by at least two hours, as these can reduce absorption. Keep regular follow-ups for lipid panels and safety labs. If you miss appointments or stop therapy, your cholesterol can rise again.

People of certain ancestries and those with kidney impairment may require lower doses. If you are prescribed other interacting medicines, your prescriber may choose a different starting point. Always consult the official label or your healthcare professional when unsure.

Strengths and Forms

Rosuvastatin is supplied as film-coated tablets. Commonly available strengths include 5 mg, 10 mg, 20 mg, and 40 mg. Availability can vary by manufacturer and market. Some pack sizes and tablet colors differ between brands and generics. Ask before you order if you need a specific presentation.

An example listing you may see is a rosuvastatin calcium 20 mg tablet. Your prescriber will select the strength that fits your treatment goals and medical history.

Missed Dose and Timing

If you miss a dose, take it when you remember. If it is close to the time for your next tablet, skip the missed dose and resume your schedule. Do not take two doses at once. Try using a daily reminder or pill organizer to support consistent use.

Storage and Travel Basics

Store tablets at room temperature in a dry place away from moisture and direct light. Keep the bottle tightly closed and out of reach of children and pets. Do not store medicines in a bathroom cabinet with high humidity or in a hot car.

When you travel, carry the medication in your hand luggage with the original labeled container. Pack a small extra supply if your trip may be extended. Bring a copy of your prescription and your prescriber’s contact information. If crossing borders, allow time for security checks and keep medicines accessible for inspection. Use reminders on your phone to avoid missed doses in different time zones.

Benefits

As part of a comprehensive plan, this medicine lowers LDL and non-HDL cholesterol and can reduce triglycerides. It has once-daily dosing and can be taken with or without food. It may be combined with other lipid-lowering therapies when additional reduction is needed.

Consistent use alongside diet, exercise, and smoking cessation can support long-term cardiovascular health. Your prescriber may monitor labs to confirm your response.

Side Effects and Safety

• Headache
• Muscle aches or weakness
• Abdominal pain
• Nausea
• Constipation

Serious but rare effects include myopathy or rhabdomyolysis, liver enzyme elevations, and severe allergic reactions. New or unexplained muscle pain, dark urine, or marked fatigue require prompt medical attention. Small increases in blood sugar have been reported with statins. Protein in urine and hematuria have occurred, typically transient. The risk of muscle issues may be higher with factors like advanced age, hypothyroidism, kidney problems, or interacting medicines.

Drug Interactions and Cautions

Tell your prescriber about all medicines and supplements you use. Important interactions include cyclosporine, some HIV or hepatitis C antivirals, gemfibrozil, other fibrates, and high-dose niacin. Warfarin may require closer INR checks when starting or changing the dose. Separate aluminum/magnesium antacids by at least two hours. Limit alcohol intake because of liver safety.

Report muscle symptoms, especially if accompanied by fever or malaise. Your prescriber may pause therapy during serious acute illnesses or major surgery. Review any unplanned pregnancy immediately, as this treatment is not used during pregnancy.

What to Expect Over Time

Cholesterol levels are often checked a few weeks after starting or adjusting therapy. Your dose may be fine-tuned to reach targets set by your clinician. Many people feel no obvious effects day to day, so lab results guide progress. Keep taking the tablets even when you feel well, unless your prescriber advises a change.

Pair the treatment with a heart-healthy diet, regular activity, and weight management. Set simple routines, like taking your dose after brushing your teeth or with breakfast, to support steady use. If adherence is difficult, ask about tools and reminders that can help.

For broader context on cholesterol care, see our article The Skinny On High Cholesterol.

Compare With Alternatives

Other statins may be considered. Atorvastatin is a widely used option with flexible dosing. For patients needing combination therapy, Ezetimibe can be added to a statin to further lower LDL by reducing intestinal cholesterol absorption. Your prescriber will consider goals, interactions, and tolerability when choosing an approach.

Pricing and Access

Canadian generics can offer value for US patients paying cash. You can check current pricing, compare pack sizes, and review availability before you order. Some shoppers search for a rosuvastatin 20 mg cash price; your total will reflect the tablet strength, pack size, and manufacturer.

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Availability and Substitutions

Generic rosuvastatin comes from several manufacturers. Tablet color, imprint, or shape can differ between suppliers, but the active ingredient and labeled strength remain the same. If a specific strength or brand is not available, your prescriber may recommend an alternative option with similar effects. We cannot confirm restock dates in advance.

Patient Suitability and Cost-Saving Tips

Good candidates are adults with high LDL or mixed dyslipidemia who need statin therapy. It is not suitable in pregnancy or while breastfeeding. People with active liver disease or a history of severe statin-related muscle problems may need different care plans.

To save on costs, consider multi-month supplies if your prescriber agrees. Align your refills with scheduled lab checks to avoid gaps. Set automated reminders for reorders so you do not run out. If your clinician adjusts your plan, update your order early to prevent unnecessary delays.

Explore related categories for more options in heart care, including our Cardiovascular selection and resources for Familial Hypercholesterolemia management.

Questions to Ask Your Clinician

• What LDL goal should I target with this therapy?
• How soon should I return for labs to check my response?
• Do my current medicines increase the risk of muscle side effects?
• Should I separate this tablet from any antacids or supplements?
• What lifestyle changes will best support my lipid goals?
• If I develop muscle pain, what steps should I take?

Authoritative Sources

FDA DailyMed: Rosuvastatin Calcium

US Prescribing Information: Crestor

Health Canada Drug Product Database

Ready when you are. Place your order with prompt, express shipping with temperature-controlled handling when required. This information is not a substitute for medical advice; always follow your prescriber’s guidance and the official label.