Tresiba® FlexTouch Pens (Insulin Degludec) for Basal Control

What Tresiba® Is and How It Works

Tresiba® (insulin degludec) is a long-acting basal insulin for adults and children with diabetes. It provides up to 42 hours of background insulin with once-daily dosing. The FlexTouch pen delivers prefilled U-100 or U-200 insulin. Many people compare options when they need Tresiba FlexTouch Pens without insurance. You can order Tresiba FlexTouch Pens through a licensed Canadian pharmacy at fair pricing.

At YouDrugstore, a licensed Canadian pharmacy based in Manitoba, prescriptions are reviewed by licensed pharmacists before dispensing. We offer brand and generic medicines at Canadian prices, and we also carry OTC health products. Friendly customer-service chat is available during posted office hours, and pharmacists can address medication questions.

Tresiba® helps control fasting and between-meal blood glucose in type 1 and type 2 diabetes. It is injected subcutaneously once daily, at any time of day. The pen design allows smooth dosing with low injection force. U-100 pens deliver up to 80 units per injection. U-200 pens deliver up to 160 units per injection in 2-unit steps.

We source medicines from licensed and vetted international partner pharmacies to offer authentic brand products across a broad selection at affordable prices.

Dosage and Usage

Use Tresiba® as directed by a prescriber. Typical use patterns include:

• Type 2 diabetes: common starting dose is 10 units once daily, then titrate based on fasting glucose and care plan.
• Type 1 diabetes: basal insulin often makes up about one-third to one-half of total daily insulin, with rapid-acting insulin for meals.
• Administer subcutaneously in the thigh, abdomen, or upper arm. Rotate sites with each injection.
• Do not mix or dilute Tresiba® with other insulins. Do not use in an insulin pump or by IV.
• Prime the FlexTouch pen with 2 units before each injection to ensure flow.
• If a dose is missed, inject when remembered, then ensure at least 8 hours between doses. Resume the usual schedule.
• Allow 3–4 days to reach steady state after changes in dose.

Storage and travel tips:

• Keep unopened pens refrigerated at 2–8 °C (36–46 °F). Do not freeze. If frozen, discard.
• In use: store at room temperature (below 30 °C/86 °F) for up to 8 weeks (56 days). Keep away from heat and light. Do not refrigerate in-use pens.
• Keep the cap on to protect from light. Remove the needle after injection.
• Use a travel cooler with ice packs for long trips. Keep pens out of checked luggage.
• Do not share pens or needles. Use a new needle for every injection.

Benefits and Savings

Tresiba® provides stable, ultra-long action with low day-to-day variability. Flexible dosing time can improve adherence. Many patients report fewer nocturnal lows compared with some basal alternatives. U-200 pens help reduce the number of clicks for higher doses, which may improve comfort.

Ordering through YouDrugstore can reduce costs by 60–80% versus typical US prices. We offer brand insulin at Canadian pricing, and our team can help with questions during posted hours. Savings may be helpful if buying Tresiba FlexTouch Pens without insurance or when managing a high deductible.

If you are also managing meal-time control or frequent highs, review our Diabetes and Hypoglycemia resources for supportive information.

Side Effects and Safety

Common effects are usually mild and tend to improve with time. Serious effects need prompt medical care.

• Common: hypoglycemia, injection site redness or itch, lipodystrophy at injection sites, mild edema, weight gain.
• Less common: allergic reactions (rash, hives), visual changes, headache.
• Serious: severe hypoglycemia (confusion, seizures), hypokalemia, generalized hypersensitivity, worsening heart failure when combined with a thiazolidinedione, diabetic ketoacidosis if insulin is stopped.

Concomitant medicines can raise or lower insulin needs. Beta blockers may mask hypoglycemia symptoms. Corticosteroids, diuretics, and sympathomimetics may increase glucose. Alcohol can raise or lower glucose. Use in pregnancy or breastfeeding requires clinical oversight. Pediatric use: Tresiba® U-100 is approved from age 1; U-200 is not recommended in children. Never share pens.

Onset Time

Tresiba® begins to reduce glucose within 1–2 hours. The action is flat and lasts beyond 24 hours, up to 42 hours in many patients. Full steady state is reached after about 3–4 days of the same daily dose. This long half-life supports once-daily dosing at a consistent time.

Compare With Alternatives

Basal insulin options differ in duration, device, and dose limits. Lantus (insulin glargine U-100) provides about 24 hours of action. It has a long safety record and broad availability. Toujeo (insulin glargine U-300) offers longer action than Lantus with smaller injection volume for high doses.

Neutral protamine Hagedorn (NPH) is an older basal option with lower upfront cost. It often needs twice-daily dosing and has more pronounced peaks, which can raise nocturnal hypoglycemia risk compared with analogs.

Some regimens pair Tresiba® with separate mealtime insulin. Regular human insulin remains a choice for meals but has slower onset than analogs; see Humulin® R Vial. Rapid analogs such as insulin aspart act faster for prandial spikes. Options include Novorapid® Vial and Fiasp® Vial, which differ mainly in onset speed and formulation additives.

GLP-1 receptor agonists, such as dulaglutide, can reduce A1C and weight when added to basal insulin. For background on that class, see our article Thinking About Trulicity Weight Loss Read This First.

Combination Therapy

Tresiba® supplies basal insulin. Many patients still need mealtime insulin. Rapid-acting analogs target post-meal spikes. Dosing ratios and correction factors should follow an individualized plan from a prescriber.

Do not mix Tresiba® with other insulins in the same syringe. Do not use Tresiba® in an insulin pump. In type 1 diabetes, basal insulin must be combined with prandial insulin. In type 2 diabetes, Tresiba® may be paired with GLP-1 RA, metformin, SGLT2 inhibitors, or other agents when appropriate.

Patient Suitability and Cost-Saving Tips

Tresiba® may fit patients who want once-daily basal coverage with flexible timing. It is suitable across a wide dose range, including higher doses with U-200 pens. It is not for treatment of diabetic ketoacidosis and not for intravenous use. Suitability depends on medical history, other medicines, and glucose goals.

To manage cost, consider multi-month supplies to lower per-month costs. We also offer reorder reminders so you can avoid gaps. For current offers and bulk options, see our Tresiba FlexTouch Pens coupon page.

You can place your order online or by phone. Our team supports importing for personal use where permitted. Savings are often meaningful for those facing Tresiba FlexTouch Pens no insurance expenses or paying cash price out of pocket.

Authoritative Sources

Novo Nordisk Tresiba Product Page

Health Canada Drug Product Database: Tresiba

FDA Prescribing Information: Tresiba

YouDrugstore makes it simple to order authentic basal insulin at Canadian prices. Our Manitoba-based team processes your prescription with care and offers customer-service chat during posted hours. We provide prompt, express, cold-chain shipping to protect temperature-sensitive products from our door to yours.

This page is for general information only and does not replace advice from your healthcare professional. Always follow your prescriber’s directions and the patient information leaflet. Keep medicines out of reach of children.