Vitrakvi® Capsules and Oral Solution for Cancer with NTRK Gene Fusion

Vitrakvi® is a targeted cancer medicine used for solid tumors that have an NTRK gene fusion. This page explains approved uses, dosing basics, side effects, and how to access therapy with US delivery from Canada. It also covers the Vitrakvi price without insurance so you can plan your budget.

What Vitrakvi Is and How It Works

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Vitrakvi® contains larotrectinib, a TRK inhibitor. It blocks abnormal TRK fusion proteins that drive tumor growth in certain cancers. The treatment is tissue‑agnostic, meaning it may be used for different solid tumors once an NTRK gene fusion is confirmed by a validated test. It is taken by mouth and can be used in adults and children.

This medicine may help control tumor growth. Your prescriber will consider your overall health, prior therapies, and lab results to determine if this option fits your care plan. For background on this condition, see our category for Cancer With NTRK Gene Fusion.

Who It’s For

This therapy is indicated for adult and pediatric patients with solid tumors that test positive for an NTRK gene fusion. A reliable laboratory test is required before starting. It is generally used when no satisfactory alternative treatments exist or after disease progression on prior therapies, per the approved labeling.

People who have had severe reactions to the ingredients should not take it. Tell your healthcare professional if you are pregnant, planning pregnancy, or breastfeeding. Discuss liver problems, neurologic conditions, or any history of fractures. Children may need monitoring for growth and bone health per label guidance.

Explore our broader oncology selection under Cancer.

Dosage and Usage

The class is typically taken by mouth twice daily, with or without food. Swallow capsules whole. If using the oral solution, measure doses with the provided syringe, not a household spoon. Take doses at the same times each day to support consistent exposure.

If your clinician adjusts the dose for side effects or interacting medicines, follow their directions and the official label. Avoid grapefruit or grapefruit juice because of interaction potential. Do not change your dosing schedule without discussing it with your prescriber. Keep all lab and imaging appointments to help monitor response and safety.

Strengths and Forms

• Capsules: 25 mg and 100 mg
• Oral solution: 20 mg/mL

Not all strengths or forms may be available at all times. Check the product page for current options. For those comparing capsules, you can review the Vitrakvi 100 mg capsules price and related details when selecting your fill. The oral liquid uses a dosing syringe for accurate measurement.

Missed Dose and Timing

If you miss a dose, take it when you remember unless it is close to your next scheduled dose. In that case, skip the missed dose and take the next dose at the normal time. Do not double up to make up for a missed dose. If you vomit after a dose, take the next dose at the usual time. Refer to the official prescribing information for scenario‑specific guidance.

Storage and Travel Basics

Store capsules at room temperature in the original container, tightly closed, and out of reach of children. Keep away from excessive heat, moisture, and light. The oral solution is commonly kept refrigerated; do not freeze. Ask your pharmacist about beyond‑use dates after opening the bottle and any special handling steps for the liquid.

For travel, carry your medicine in your hand luggage with the pharmacy label attached. Bring your prescription details and a dosing schedule if you cross time zones. Keep the oral solution upright and secure. If you need cooler storage for the liquid during travel, plan ahead with insulated carriers and confirm requirements with your care team.

Benefits

This targeted therapy addresses tumors driven by TRK gene fusions. It can be used across solid tumor types once an eligible biomarker is confirmed. An oral form offers dosing convenience for many patients, including children when a liquid is needed. Your care team will review response and tolerability over time and may adjust the plan according to the label.

Side Effects and Safety

• Fatigue or tiredness
• Nausea or vomiting
• Constipation or diarrhea
• Dizziness or headache
• Cough
• Increased liver enzymes on blood tests
• Weight gain or appetite changes

Serious or rare risks include liver problems, neurologic effects such as balance or mood changes, and possible fractures, especially in growing children. Tell your prescriber right away about jaundice, severe dizziness, unusual bleeding, or new bone pain. Review the full safety profile in the official label. This medicine may harm an unborn baby; use effective contraception as advised.

Drug Interactions and Cautions

Larotrectinib is affected by CYP3A. Strong CYP3A inhibitors or inducers can change blood levels, which may require prescriber‑directed adjustments per the label. Limit grapefruit products. Discuss all medicines, vitamins, and herbal supplements you take, including St. John’s wort. People with moderate or severe liver impairment need careful assessment. Do not breastfeed during treatment and for the timeframe listed in the official labeling.

For broader oncology context, you can read our guide on Immunotherapy For Cancer. Note that immunotherapies work differently from TRK inhibitors.

What to Expect Over Time

Your clinician will check how you are doing with physical exams, labs, and imaging. Some people notice side effects early, which may settle or require changes guided by the label. Treatment is typically continued until disease progression or unacceptable toxicity. Keep a simple dosing log to support adherence. Report new symptoms promptly so your team can adjust care if needed.

Compare With Alternatives

Other targeted options may be considered based on tumor genetics:

• Xalkori®: an ALK/ROS1 inhibitor used for select gene‑driven lung cancers. Different targets and indications from TRK inhibitors.
• Retevmo®: a RET inhibitor for certain RET‑altered cancers. Suitability depends on biomarker testing and label criteria.

These therapies are not interchangeable. Your oncology team will match treatment to your specific biomarker results and medical history.

Pricing and Access

We offer Canadian pharmacy options with transparent information on larotrectinib price so you can compare choices with your prescriber. You may also see larotrectinib 25 mg price when selecting strength and form. For cross‑border convenience, we provide US shipping from Canada on eligible orders. Final amounts can vary by strength, quantity, and form.

Looking for potential savings or current offers? See our Promotions page for any available site deals. Checkout is encrypted to protect your information.

Availability and Substitutions

Supply can change by strength and form. If a requested option is not available, your prescriber may recommend an alternative from the same class or another appropriate therapy. You can review the Vitrakvi oral solution price when the liquid is listed. For other targeted medicines in oncology, you may also wish to review Piqray® with your clinician for relevant indications.

Patient Suitability and Cost-Saving Tips

This therapy may suit patients with a confirmed NTRK gene fusion and adequate organ function. Those with unmanaged liver disease, certain neurologic conditions, or pregnancy should discuss risks carefully. Ask about financial counseling, manufacturer support, and pharmacy options.

• Multi‑month fills: Fewer refills can reduce per‑fill fees.
• Refill reminders: Set simple alerts to avoid gaps.
• Generic name search: Compare larotrectinib 100 mg price across options.
• Coverage review: Coordinate with your insurer and oncology team.

Questions to Ask Your Clinician

• Is my tumor confirmed to have an NTRK gene fusion?
• Which form suits me best, capsules or oral solution?
• How will we monitor response and safety?
• Which medicines, foods, or supplements should I avoid?
• What signs should prompt a call between visits?
• How might dose adjustments be handled if I have side effects?

Authoritative Sources

FDA DailyMed: Vitrakvi Prescribing Information

Health Canada DPD: Vitrakvi

Manufacturer: Bayer

Ready to proceed? You can start your order with prompt, express shipping and temperature-controlled handling when required. This information is educational and does not replace guidance from your healthcare professional.