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Xospata

Cancer

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Xospata is a medicine used to treat a type of blood cancer called acute myeloid leukemia (AML) in adults who have a specific gene mutation known as FLT3. It works by blocking the FLT3 protein, which helps stop the cancer cells from growing and spreading.

Benefits

  • Targets and blocks the FLT3 gene mutation that drives some AML cases.
  • Helps slow down or stop the growth of cancer cells.
  • Taken as a once-daily tablet, making treatment easier to manage at home.
  • Offers an option for patients whose AML has come back or hasn’t responded to other treatments.
  • Shown to improve survival in some patients with FLT3-mutated AML.

Dosage

  • The usual dose is 120 mg once a day.
  • Take it at the same time each day, with or without food.
  • Swallow the tablets whole — don’t crush or chew.
  • Your doctor may adjust the dose based on how your body responds.

Warnings and Precautions

  • Can affect your heart rhythm — your doctor will monitor you with ECGs and blood tests.
  • May raise liver enzyme levels — regular blood tests are needed.
  • Can cause a serious condition called differentiation syndrome — report any new symptoms right away.
  • Not safe in pregnancy or breastfeeding — use effective birth control during treatment.
  • Tell your doctor about all medications you’re taking to avoid harmful interactions.

Usage Instructions

  • Take exactly as prescribed, once a day, every day.
  • Don’t skip doses or stop treatment unless your doctor tells you to.
  • If you miss a dose, take it as soon as you remember — if it’s close to the next dose, skip the missed one.
  • Stay hydrated and follow up regularly for blood tests and checkups.

Storage Information

  • Store at room temperature, away from heat, moisture, and light.
  • Keep the tablets in their original packaging.
  • Keep out of reach of children.

Common Side Effects

  • Mild to moderate effects: tiredness, nausea, diarrhea, loss of appetite, joint or muscle pain, and abnormal liver tests.
  • Serious (seek medical help): heart rhythm problems (fast or irregular heartbeat), signs of liver damage (yellowing of skin or dark urine), fever, swelling, shortness of breath, or sudden weight gain (which may be signs of differentiation syndrome).

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