Apixaban (Generic for Eliquis®) Tablets for Stroke and Clot Prevention

What Apixaban Is and How It Works

Apixaban is an oral anticoagulant in the direct factor Xa inhibitor class. It lowers the risk of stroke and systemic embolism in nonvalvular atrial fibrillation, and treats and prevents deep vein thrombosis and pulmonary embolism. Many shoppers compare apixaban price with the brand to manage costs. Some also search for eliquis coupon no insurance when reviewing options. You can order through YouDrugstore, a licensed Canadian pharmacy in Manitoba. Our pharmacists review prescriptions before dispensing. We offer brand and generic options at Canadian prices, and our customer-service chat is available during posted office hours.

Apixaban blocks factor Xa to reduce clot formation. It is taken by mouth, usually twice daily. Peak levels occur about three to four hours after a dose. We work with licensed, vetted international partner pharmacies when needed to maintain authentic brands, broad selection, and fair pricing.

Dosage and Usage

Your prescriber sets your regimen based on your condition and risk. Typical patterns:

• Atrial fibrillation stroke prevention: 5 mg twice daily is common.
• Reduced dose (2.5 mg twice daily) may be used if two apply: age 80 years or older, body weight 60 kg or less, or serum creatinine 1.5 mg/dL or higher.
• Acute DVT or PE treatment: 10 mg twice daily for 7 days, then 5 mg twice daily.
• Prevention of recurrent DVT/PE: 2.5 mg twice daily after at least 6 months of treatment.
• Post–hip or knee replacement prophylaxis: 2.5 mg twice daily, started 12–24 hours after surgery, for the prescribed duration.

Missed dose guidance:

• Take the missed tablet as soon as you remember on the same day.
• Resume your regular twice-daily schedule. Do not double up.

Storage and travel tips:

• Store at 20–25°C (68–77°F) in a dry place.
• Keep tablets in the original packaging.
• When traveling, carry your supply in hand luggage with a copy of your prescription.
• Avoid heat and humidity, and keep away from children and pets.

Do not change your dose or stop treatment without medical guidance. Report signs of bleeding promptly to your clinician.

Benefits and Savings

Apixaban reduces the risk of stroke in nonvalvular atrial fibrillation and treats active clots. It lowers recurrence of DVT and PE when continued at the extended prophylactic dose. It offers a stable effect without routine INR monitoring and has fewer food interactions than warfarin. Twice-daily dosing supports steady coverage.

Buying through YouDrugstore often provides 60–80% savings compared with typical US prices. We carry generic apixaban and the brand Eliquis®. Many patients manage costs even without insurance by choosing a multi-month supply. Our team can also set simple reorder reminders so you do not run short.

Side Effects and Safety

Common effects are related to bleeding risk. Speak with your healthcare provider if symptoms are concerning or persistent.

• Common: easy bruising, nosebleeds, gum bleeding, minor cuts that bleed longer, anemia, nausea.
• Less common: dizziness, fatigue, mild rash.
• Serious: black or bloody stools, vomiting blood, coughing blood, severe headache, sudden weakness, vision changes, prolonged heavy bleeding, spinal or epidural hematoma symptoms (back pain, numbness, weakness).

Contraindications include active pathological bleeding and hypersensitivity to apixaban. Use with caution in severe hepatic impairment. Dose adjustments or careful monitoring may be needed with kidney disease. Avoid strong dual CYP3A4 and P-gp inducers (such as rifampin) which can reduce effectiveness, and strong inhibitors (such as ketoconazole, ritonavir) which can increase drug levels. Alcohol and NSAIDs may increase bleeding risk. Apixaban is not recommended in patients with mechanical heart valves.

Pregnancy and breastfeeding require individualized assessment. Human data are limited. Discuss family planning, pregnancy, or lactation with your prescriber before starting or continuing therapy.

Onset Time

Apixaban begins to work within hours. Peak concentration occurs about three to four hours after a dose. Clinical protection from stroke or recurrent clots depends on consistent dosing over days to weeks. Do not skip doses once you start.

Compare With Alternatives

Apixaban is one of several direct oral anticoagulants (DOACs). Xarelto® (rivaroxaban) is another factor Xa inhibitor. It is often taken once daily for atrial fibrillation, and has different dosing for DVT/PE. Choice may depend on bleeding risk, kidney function, and dosing preference. The brand Eliquis® contains apixaban; switching from brand to generic is typically straightforward when the same strength is used.

Dabigatran (Pradaxa) is a direct thrombin inhibitor. It can be suitable for some patients but may have different gastrointestinal tolerability and specific storage needs. Warfarin is a vitamin K antagonist with long clinical experience, dietary considerations, and INR monitoring. Your clinician will match therapy to your history, procedures, and risk factors.

For a broader comparison, you may find the article Xarelto Vs Eliquis Which Anticoagulant Suits You Best helpful.

Combination Therapy

Apixaban is often used alone. Combining it with other anticoagulants increases bleeding risk and is usually avoided. Doctors may pair apixaban with a single antiplatelet agent for a limited time after certain procedures, such as coronary stenting, based on current guidelines. Discuss all prescription drugs, OTC pain relievers, and supplements with your care team before starting apixaban. Be cautious with aspirin, clopidogrel, ticagrelor, NSAIDs, fish oil, and herbal products that affect bleeding.

Patient Suitability and Cost-Saving Tips

Good candidates include adults with nonvalvular atrial fibrillation who need stroke prevention, and patients being treated for, or preventing recurrence of, DVT or PE. People with active bleeding, severe uncontrolled hypertension, or recent major surgery may need a different plan. Tell your clinician about past bleeding, falls, kidney or liver disease, and planned procedures.

To manage costs, compare generic and brand options and consider a longer supply. Multi-month fills often lower the per-month cost. We offer reorder reminders so you can maintain continuity. For education, read Types Of Anticoagulant Drugs Which One Is Right For You, and review condition pages such as Atrial Fibrillation and Deep Vein Thrombosis.

If you are purchasing without insurance, you may still see strong savings with Canadian pricing and generic options. For current offers and bulk options, see our eliquis coupon no insurance page.

Authoritative Sources

Review official information before starting therapy. See the Eliquis (apixaban) Prescribing Information by Bristol Myers Squibb/Pfizer, consult the Health Canada Drug Product Database entry for apixaban, and read the FDA Medication Guide for Eliquis.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. We meet Canadian pharmacy standards, and a licensed pharmacist reviews every prescription. Order online or by phone, and reach our friendly customer-service chat during posted office hours. We ship to the US with prompt, express, cold-chain shipping.

This information is not a substitute for professional medical advice. Always follow your prescriber’s directions and read the patient leaflet that comes with your medication.