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Celebrex® Capsules for Osteoarthritis
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Celebrex® is a prescription NSAID capsule used to relieve arthritis pain and stiffness. It contains celecoxib, a COX-2 selective medicine that helps reduce inflammation. This page explains uses, safety, and practical details to help you access treatment with US delivery from Canada, even if you pay without insurance.
What Celebrex Is and How It Works
This medicine belongs to the COX-2 selective NSAID class. It reduces prostaglandin production, which can ease joint pain, swelling, and tenderness. It may be used for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, and painful menstrual cramps when prescribed.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
It works by targeting the COX-2 pathway more than COX-1. That selectivity can lower the chance of some stomach issues seen with certain other NSAIDs, though risks remain. Your prescriber will decide if this therapy fits your condition and history.
Who It’s For
This treatment is used in adults for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and short-term relief of acute pain, including primary dysmenorrhea. For juvenile rheumatoid arthritis, clinicians may prescribe it for certain children when benefits outweigh risks and label criteria are met.
Avoid use if you have had asthma, hives, or allergic reactions with aspirin or other NSAIDs, or if you have a known sulfonamide allergy. Do not use right before or after coronary artery bypass graft surgery. People with active gastrointestinal bleeding, severe liver or kidney problems, or uncontrolled heart failure should not use it unless a prescriber determines it is appropriate. Use is generally avoided from 20 weeks of pregnancy onward due to fetal risks.
Learn more about conditions it may treat in our guides to Osteoarthritis, Rheumatoid Arthritis, and Pain Inflammation.
Dosage and Usage
Follow your prescription label. Doses and schedules differ by diagnosis and your response. Many adults with osteoarthritis take once-daily or twice-daily dosing. Rheumatoid arthritis often uses twice-daily dosing. For acute pain or menstrual cramps, the first day may include an initial higher dose followed by smaller doses as directed.
Your clinician may prescribe Celecoxib 200mg for certain arthritis plans. It can be taken with or without food. Swallow capsules whole with water. If you have difficulty swallowing, a pharmacist or prescriber can advise on options described in the product label.
Use the lowest effective dose for the shortest duration that manages your symptoms. Do not change your dose without medical guidance. If you are also taking low-dose aspirin for heart protection, discuss the balance of benefits and gastrointestinal risk with your prescriber.
Strengths and Forms
This prescription comes as oral capsules in commonly available strengths. Availability can vary by manufacturer and country.
- celecoxib 100 mg capsule
Your prescriber will choose the capsule strength that fits your condition and response. Not all strengths are stocked at all times.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to the time for your next dose. If it is near the next scheduled dose, skip the missed capsule and return to your usual time. Do not take two doses at once. For short-term pain regimens, follow your prescriber’s instructions closely.
Storage and Travel Basics
Store capsules at room temperature in a dry place away from moisture and direct heat. Keep the container tightly closed and out of reach of children and pets. Do not store in the bathroom. For travel, keep the medicine in original labeled packaging and carry a copy of your prescription. Pack it in your carry-on if flying, along with a medication list. If your trip spans time zones, keep to your normal interval spacing based on hours between doses.
Benefits
This COX-2 selective therapy can relieve pain and stiffness from common arthritic conditions. Many people appreciate once-daily or twice-daily dosing and flexible administration with or without food. COX-2 selectivity may reduce some stomach-related risks compared with certain nonselective NSAIDs, but serious gastrointestinal and cardiovascular risks can still occur.
Side Effects and Safety
- Common: stomach upset, heartburn, diarrhea, gas
- Headache or dizziness
- Swelling in legs or feet
- Elevated blood pressure
- Respiratory or cold-like symptoms
Serious effects can include gastrointestinal bleeding or ulcers, heart attack, stroke, kidney problems, liver injury, and severe skin reactions. Seek immediate help for chest pain, shortness of breath, weakness on one side, black stools, or severe rash. The risk of gastrointestinal bleeding increases with age, a history of ulcers, alcohol use, smoking, and concurrent anticoagulants, antiplatelets, or corticosteroids.
Drug Interactions and Cautions
Tell your prescriber about all medicines and supplements you use. Interactions may occur with anticoagulants like warfarin, antiplatelets such as aspirin, SSRIs and SNRIs, ACE inhibitors, ARBs, diuretics, lithium, methotrexate, and certain CYP2C9 inhibitors or inducers. Combining with other NSAIDs increases adverse effect risk. Alcohol can irritate the stomach and raise bleeding risk. Blood pressure may rise during therapy; monitoring may be advised.
What to Expect Over Time
Relief of pain and stiffness may occur as your schedule is established. Ongoing conditions like osteoarthritis often need steady dosing to maintain effect. Your prescriber may reassess the plan based on benefits, tolerability, and your medical history. Report new stomach pain, unusual bruising, shortness of breath, swelling, or severe fatigue promptly.
Compare With Alternatives
Clinicians may consider other NSAIDs if this option is not suitable. Two common alternatives include Meloxicam and Naproxen. Choice depends on condition, risk factors, and your response to therapy.
Pricing and Access
We offer Canadian retail options with transparent pricing. Many customers compare celecoxib price without insurance to understand potential savings versus typical US cash rates. See current selections and supply options for your prescription. For tips and seasonal offers, visit our Promotions page. Ships from Canada to US is available on approved orders. Checkout uses encrypted technology to protect your information.
Availability and Substitutions
Both brand and generic products may be available. Your prescriber may authorize substitution based on your local regulations and clinical needs. If the brand is not in stock, an equivalent strength of celecoxib generic may be recommended if appropriate for your prescription. Availability can vary by strength and manufacturer. We do not provide restock dates.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults needing relief from osteoarthritis or other approved indications when benefits outweigh risks. People with high cardiovascular risk, a history of ulcers or bleeding, severe kidney or liver disease, or late pregnancy generally require alternatives. Discuss your full medical history, including stomach problems and blood pressure, before starting.
Ask your prescriber if a multi-month fill is reasonable for your plan. Larger fills can reduce per-fill fees and simplify adherence. Set calendar alerts for refills. If your clinician specifies strength changes over time, ensure the pharmacy updates your supply consistently. Some plans specify Celebrex 200mg, while others use lower or divided doses; your label is the authority.
Questions to Ask Your Clinician
- Is this NSAID appropriate for my condition and risks?
- What dose and schedule fit my diagnosis?
- Should I take it with food to reduce stomach upset?
- How does it interact with my blood pressure medicines?
- Do I continue aspirin or stop it with this therapy?
- What signs of bleeding or heart problems should I watch for?
Authoritative Sources
Pfizer Product InformationFDA DailyMed: Celecoxib CapsulesHealth Canada Drug Product Database
Storage and Travel Basics
Keep capsules in a child-resistant container, away from light and excess heat. Do not use the product past the labeled expiry date. If traveling for an extended period, bring enough supply and a copy of your prescription. Pack an updated medication list in case care is needed away from home.
Side Effects and Safety
Contact your healthcare professional if side effects persist or worsen. Using the lowest effective dose for the shortest time may help reduce risks. If you take insulin or sulfonylureas for diabetes, monitor for changes in blood glucose as advised, since illness and pain can affect control.
Helpful Reading
Learn more in these resources: Arthritis Drugs, Most Common Forms, and Lower Back Pain.
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How is this medicine different from other NSAIDs?
It preferentially inhibits the COX-2 enzyme, which helps reduce inflammation while often sparing more COX-1 activity. That selectivity may lessen some stomach risks seen with certain nonselective NSAIDs, but serious gastrointestinal and cardiovascular risks remain. Your overall risk depends on your history, dose, duration, and other medicines. Your prescriber will weigh these factors when deciding if celecoxib is appropriate for you.
Can I take it with food or alcohol?
You can take it with or without food. Taking it with food may help reduce stomach upset for some people. Alcohol can irritate the stomach and increase bleeding risk, especially when combined with NSAIDs. If you drink, limit intake and discuss your habits with your prescriber. Report black stools, persistent heartburn, or sharp stomach pain promptly.
Is there a generic version available?
Yes. A celebrex generic option is celecoxib, which is the same active ingredient as the brand. Your prescriber may authorize substitution depending on your location, prescription details, and availability. Capsule strengths vary by market. If you have questions about switching between manufacturers, speak with your pharmacist or clinician.
What if I am pregnant or breastfeeding?
Use is generally avoided from 20 weeks of pregnancy onward because it may affect the fetal ductus arteriosus and amniotic fluid. During earlier pregnancy, risks and benefits must be carefully weighed with your clinician. If you are breastfeeding, limited amounts may pass into milk; your prescriber will help determine if the therapy is appropriate or if other options fit better.
Can I take it with low-dose aspirin?
Some people use low-dose aspirin for cardiovascular protection. Combining aspirin with an NSAID can increase gastrointestinal risk. Your prescriber may decide the combination is appropriate for you and may add protective strategies when needed. Do not start or stop aspirin without medical advice. Watch for black stools, stomach pain, or unexplained weakness.
What should I do if I miss a dose?
Take it when you remember unless it is close to your next dose. If it is near the next scheduled time, skip the missed dose and resume your usual schedule. Do not take two doses at once. If you repeatedly miss doses or are unsure about your schedule, ask your pharmacist or clinician for help planning a routine.
How soon might I notice relief?
Some people notice symptom relief after the first doses, especially for acute pain. Conditions like osteoarthritis may require consistent use as prescribed. Response varies and depends on dose, condition, and other factors. If your symptoms do not improve or you develop side effects, contact your healthcare professional for guidance rather than changing your dose yourself.

