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Clobetasol® Cream and Ointment for Psoriasis and Eczema
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Clobetasol is a high-potency topical corticosteroid used for short courses on stubborn skin conditions. This page explains forms, safe use, and how to access Canadian supply with US delivery from Canada, even when paying without insurance.
What Clobetasol Is and How It Works
Clobetasol® reduces redness, swelling, and itch by calming overactive skin inflammation. It acts in the skin to suppress inflammatory signals and helps quiet plaques, thickened areas, and severe dermatitis. As a very potent steroid, this medicine is reserved for small areas and limited timeframes.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
The treatment is available in multiple vehicles so you and your prescriber can match the product to the body area and symptoms. Many people know the class from everyday discussions of topical steroids; for a plain-language overview, see our article on Topical Steroids. When appropriate, prescribers may choose a vehicle like Clobetasol propionate lotion for hair-bearing areas where a cream could be less practical.
Who It’s For
This medicine treats steroid‑responsive dermatoses such as plaque psoriasis, chronic hand eczema, lichen planus, and severe allergic or irritant dermatitis. It can also help short flares of atopic eczema when weaker options are not enough. It is not for acne, rosacea, diaper rash, or routine cosmetic use. Children may be more susceptible to absorption; pediatric use should follow label guidance and prescriber direction.
Avoid use on the face, groin, or skin folds unless your prescriber instructs otherwise. Do not use on broken skin or infected lesions unless the infection is being treated. People with known hypersensitivity to corticosteroids should not use it. Some may recognize related brands, including the historical reference to Temovate cream, which contains the same active ingredient.
Learn more about conditions it may support in our condition pages for Eczema, Psoriasis, and Dermatitis.
Dosage and Usage
Use a thin film to the affected skin as directed, typically once or twice daily for a short period. Rub in gently. Wash hands after applying unless treating the hands. Do not cover with occlusive dressings unless your prescriber advises. For scalp regions, apply to dry skin or hair; part hair to reach the scalp before using. Avoid eyes, mouth, and intravaginal use.
This treatment is intended for limited durations. If symptoms persist, contact your prescriber rather than extending use on your own. Do not combine with other topical steroids on the same area unless directed. The gel or foam can be useful for thicker plaques, while Clobetasol propionate gel may dry quickly on areas where a cream would feel too occlusive.
For chronic conditions, your clinician may suggest stepping down to a lower‑potency steroid or a non‑steroid maintenance option after control improves. For guidance on eczema care, see our resource What Is Eczema.
Strengths and Forms
Commonly available forms include cream, ointment, gel, lotion, foam, and scalp solution. Most products are supplied at 0.05% concentration. Vehicle selection depends on body site, skin thickness, hair, and personal preference. Creams absorb quickly and suit most plaques; ointments offer more occlusion for thick lesions; lotions and foams suit hair‑bearing areas.
Brand equivalents exist in some markets. For reference, Cormax cream has been used historically as a clobetasol product name. Availability varies by manufacturer and region.
Missed Dose and Timing
If you miss a dose, apply it when remembered. If it is close to the next scheduled application, skip the missed one and resume your regular schedule. Do not double the amount to make up for a missed application. Keeping a simple routine, like morning and evening use, can help adherence and reduce overuse.
Storage and Travel Basics
Store at room temperature away from excess heat and direct sunlight. Keep the cap tightly closed and out of reach of children and pets. Do not freeze foams or aerosols. When traveling, keep the labeled container in your carry‑on if possible and pack a copy of your prescription. Avoid leaving the medicine in a hot car. If the product changes color, separates, or smells unusual, consult a pharmacist before use.
For broader dermatology topics and seasonal tips, you can also visit Dermatology and community features like World Psoriasis Day.
Benefits
This class can calm severe inflammation quickly on small areas. Short courses may smooth plaques, reduce scaling, and ease itch so you can moisturize and protect the skin more comfortably. Multiple vehicles let you match the product to the site, such as a lotion for the scalp or an ointment for thick elbows. Using the smallest effective amount helps reduce steroid exposure while controlling flares.
Side Effects and Safety
- Skin burning or stinging
- Dryness or irritation
- Redness or itching at the site
- Folliculitis or acne‑like bumps
- Skin thinning with prolonged or excessive use
Serious effects are uncommon with short, directed use. Overuse or application under occlusion can increase absorption. Potential risks include adrenal suppression, vision changes with eye exposure, stretch marks, or delayed wound healing. Stop use and contact a healthcare professional if you notice spreading infection, severe irritation, or signs of systemic steroid effects.
Drug Interactions and Cautions
Topical interactions are limited, but combining with other potent steroids on the same area may raise exposure. Occlusive dressings can increase absorption. Take care with fragile skin, especially on the face or genitals. If you use immunosuppressants or have uncontrolled skin infections, discuss risks with your prescriber. Avoid applying right before phototherapy unless your clinician instructs, as occlusion and steroid effects may alter outcomes.
For related reading on advanced eczema therapies, see Cibinqo For Eczema.
What to Expect Over Time
With appropriate use, many people notice calmer skin during the treatment period. Thick plaques may soften, and itch can ease, supporting better sleep and daily comfort. Once the flare improves, your prescriber may taper frequency or switch you to a lower‑potency steroid or a non‑steroid option for maintenance. Keep using moisturizers and gentle cleansers to support the skin barrier and reduce future flares. If symptoms return quickly after stopping, consult your clinician to review the plan.
Compare With Alternatives
For steroid‑sparing maintenance, your prescriber may suggest a calcineurin inhibitor like Protopic® Ointment. For systemic management of moderate to severe psoriasis, an oral option such as Otezla® may be considered under specialist care. Some markets also offer brand topical clobetasol products such as Clobex for specific formulations. Your clinician can help match the therapy to your diagnosis and severity.
Pricing and Access
Many patients look for ways to reduce costs, including comparing Canadian options. Our storefront reflects Canadian pharmacy pricing with US shipping from Canada. Review product pages to see available pack sizes, which can influence value based on your prescribed duration.
If you are seeking a low‑cost pathway, your prescriber may authorize a Generic for clobetasol, which typically offers strong value compared to brands. We also maintain limited offers on our Promotions page. Checkout is straightforward, and pharmacists are available for questions about form selection.
Availability and Substitutions
Supply can vary by form and manufacturer. If a specific vehicle or pack size is unavailable, your prescriber may recommend a suitable alternative vehicle or a comparable topical steroid. Prescription required and verified.
Patient Suitability and Cost-Saving Tips
This therapy suits adults and older children needing short courses for severe, localized flares. Those with thin skin areas, facial involvement, or recurrent long‑term needs may benefit from a step‑down plan or a non‑steroid maintenance option. Tell your clinician if you are pregnant, breastfeeding, or managing widespread disease that might require other treatments.
- Multi-month plan: ask about consolidating refills when clinically appropriate
- Right vehicle: pick a form that spreads well for the site
- Measured amounts: apply fingertip units to avoid waste
- Barrier care: moisturize to maintain control between flares
- Refill reminders: set calendar alerts to prevent gaps
Questions to Ask Your Clinician
- Which vehicle fits my body site and symptoms best?
- How long should I use it before stepping down?
- What signs mean I should stop and call you?
- Can I pair it with moisturizers or keratolytics?
- What is the plan for maintenance after the flare settles?
Authoritative Sources
FDA DailyMed: Clobetasol Propionate Topicals
Health Canada DPD: Clobetasol Propionate
US Labeling: Clobetasol Propionate Cream
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How long can I use clobetasol during a flare?
Most treatment plans keep clobetasol courses short, often for one to two weeks on small areas, then reassess. Your clinician may taper frequency or switch you to a lower‑potency option as control improves. Avoid continuous long‑term use on the same site because potency raises the risk of thinning and other local effects. Always follow your prescriber’s instructions and the product label for duration and frequency.
Which form should I choose for the scalp or hairy areas?
Vehicles that spread easily through hair work best on the scalp. Lotions, foams, and solutions are often preferred, while ointments can feel greasy. Apply to a dry scalp, parting the hair to reach the skin before use. If your plaques are very thick, a gel may be considered for short directed courses. Your prescriber can help match the vehicle to your symptoms and daily routine.
Can I apply clobetasol on my face or genitals?
High‑potency steroids are generally avoided on the face, groin, and skin folds unless a clinician specifically instructs and limits use. These sites absorb more medicine and are more prone to thinning and irritation. If directed to use it there, follow the prescribed schedule closely and stop if significant irritation or worsening occurs. Report sensitive site use to your clinician during follow‑up.
What should I do if the cream stings or burns after application?
A brief, mild sting can occur, especially on inflamed skin. If severe or persistent, stop and contact your prescriber. Check that you’re using a thin layer on intact skin and avoiding occlusion unless directed. Fragrance‑free moisturizers may help barrier support, applied after the steroid if advised. New or spreading redness, pus, or pain can signal infection and needs medical review.
Is clobetasol safe to use during pregnancy or breastfeeding?
Data for topical steroids suggest low risk with limited, appropriate use, but potent agents warrant caution. Use the smallest amount for the shortest time on small areas, and avoid application to the nipple/areola if breastfeeding. Your clinician will weigh severity, location, and alternatives. Discuss any planned use with your healthcare professional before starting or continuing during pregnancy or lactation.
Can I combine clobetasol with moisturizers or salicylic acid?
Many treatment plans include moisturizers for barrier repair. Use them at a different time of day or after the steroid has absorbed if your clinician advises. Keratolytics like salicylic acid may be used in some plaque‑type conditions, but layering can increase irritation. Speak with your prescriber about sequencing and which products to avoid on sensitive or broken skin.
What happens if I stop clobetasol and the rash quickly returns?
Some conditions relapse after short steroid courses. Your prescriber might suggest a step‑down steroid, a non‑steroid maintenance option, or an intermittent schedule to reduce flares. Do not extend a high‑potency steroid indefinitely without guidance. Track triggers, moisturize consistently, and schedule follow‑up to adjust your plan if rebounds occur.

