Eliquis® (Apixaban) Oral Anticoagulant Tablets for Stroke and Clot Prevention

What Eliquis® Is and How It Works

Eliquis® is the brand name for apixaban, an oral anticoagulant in the factor Xa inhibitor class. It helps prevent and treat blood clots and lowers stroke risk in nonvalvular atrial fibrillation. Tablets are usually taken twice daily. People comparing options often look at Eliquis price alongside its clinical profile and dosing convenience.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba. Orders are reviewed by licensed pharmacists before dispensing, and you can order online with customer-service chat available during posted office hours. We ship brand and generic medicines at Canadian prices and also carry OTC health products.

We work with licensed, vetted partner pharmacies internationally to source authentic brands, keep a broad selection, and offer affordable pricing.

Apixaban blocks factor Xa in the clotting cascade. This reduces thrombin generation and fibrin clot formation. It does not require routine INR monitoring. Indications include stroke prevention in nonvalvular atrial fibrillation, treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), reduction in the risk of recurrent DVT/PE, and prophylaxis after hip or knee replacement surgery.

If you are reviewing conditions like Atrial Fibrillation or Deep Vein Thrombosis, Eliquis® is a common option discussed with clinicians.

Dosage and Usage

Dosing depends on indication and patient factors such as age, weight, kidney function, and interacting drugs. Many adults take 5 mg twice daily for stroke prevention in atrial fibrillation. A reduced dose (2.5 mg twice daily) may be used when criteria such as age 80 or older, body weight 60 kg or less, or serum creatinine 1.5 mg/dL or higher apply (often two of these are needed). Treatment doses for DVT/PE start higher and then step down, following the product labeling.

• Take tablets at the same times each day, with or without food.
• If a dose is missed, take it as soon as remembered on the same day, then resume the normal schedule. Do not double the next dose.
• For surgery, dental work, or spinal procedures, prescribers may hold apixaban to lower bleeding risk. Timing depends on bleeding risk and kidney function.
• Strong CYP3A4/P-gp inhibitors (e.g., ketoconazole, itraconazole, ritonavir) and inducers (e.g., rifampin, carbamazepine, phenytoin, St. John’s wort) can change apixaban levels.
• Swallow tablets whole, or crush and suspend in water, D5W, apple juice, or mix with applesauce and take promptly.

Storage and travel tips:

• Store at 20–25°C (68–77°F). Short excursions 15–30°C are acceptable.
• Keep tablets dry in the original container, away from moisture and heat.
• When traveling, keep a supply in carry-on luggage in the labeled bottle.
• Use a reminder to keep doses about 12 hours apart when crossing time zones.

Benefits and Savings

Eliquis® lowers the risk of stroke and systemic embolism in nonvalvular atrial fibrillation. It treats DVT and PE and helps prevent recurrences. It also reduces clot risk after certain orthopedic surgeries. Twice-daily dosing offers steady coverage, and no routine INR checks are needed.

Ordering from YouDrugstore gives access to Canadian pricing and careful pharmacist review before shipping. Many customers report 60–80% savings versus typical US prices.

For current offers and bulk options, see our eliquis coupon.

Side Effects and Safety

Bleeding is the most common adverse effect. The overall profile depends on dose, age, kidney and liver function, other medicines, and procedure risks.

• Common: easy bruising, nosebleeds, gum bleeding, heavier or prolonged bleeding from cuts, mild anemia.
• Less common: gastrointestinal upset, nausea.
• Serious: major bleeding (gastrointestinal, intracranial, retroperitoneal), severe anemia, symptomatic hypotension from blood loss, hypersensitivity reactions.
• Boxed warnings: increased risk of thrombotic events with premature discontinuation; spinal/epidural hematomas may occur with neuraxial anesthesia or spinal puncture, which can cause long-term paralysis.

Apixaban is generally avoided in active pathological bleeding. Use is cautious in severe hepatic impairment and in combination with other anticoagulants or antiplatelets unless specifically directed for a clinical reason. Alcohol may increase bleeding risk. Pregnancy and breastfeeding require risk-benefit assessment with a clinician.

Onset Time

Apixaban is absorbed quickly. Peak effect usually occurs 3–4 hours after a dose. Anticoagulant effect begins the same day treatment starts. Steady-state levels are typically reached in about three days with twice-daily dosing.

Compare With Alternatives

Several anticoagulants are used for similar indications. Each has different dosing, interactions, and reversal strategies.

Apixaban is the generic form of Eliquis®. It contains the same active ingredient and is used for the same indications, following the same dosing principles.

Xarelto® (rivaroxaban) is another factor Xa inhibitor. It is often taken once daily for atrial fibrillation, and with different dosing schedules for DVT/PE. Food requirements and renal dosing differ from apixaban. See our article Xarelto Vs Eliquis Which Anticoagulant Suits You Best for a side-by-side overview.

Warfarin is a vitamin K antagonist. It remains useful for mechanical heart valves and certain indications. It requires regular INR monitoring and has many food and drug interactions. For a broader view of options, read Types Of Anticoagulant Drugs Which One Is Right For You.

Combination Therapy

Apixaban is usually used alone. Some patients may take it with low-dose antiplatelet therapy after specific cardiac procedures or for coronary disease, but bleeding risk rises when agents are combined. Avoid combining with other anticoagulants unless directed for transitions of care. Proton pump inhibitors may be considered in those at high gastrointestinal bleeding risk, based on clinician judgment.

Patient Suitability and Cost-Saving Tips

Good candidates typically include adults with nonvalvular atrial fibrillation needing stroke prevention, or those treating or preventing DVT/PE. Dose selection depends on kidney function, age, weight, and drug interactions. Patients with active bleeding or significant liver disease may not be suitable. Those with neuraxial catheters need careful planning for insertion and removal to reduce hematoma risk.

To manage costs, consider multi-month quantities to lower per-month expenses, when appropriate. You can turn on reorder reminders in your account to avoid gaps in therapy. For promotions and bulk options, check the eliquis coupon page. You may also review our information on Stroke Prevention while planning long-term care needs.

If questions arise about dosing, interactions, or timing around procedures, our pharmacists can address medication questions by phone during posted hours, and customer-service chat can help with ordering steps.

Authoritative Sources

For full prescribing details, see the manufacturer information on the BMS/Pfizer Eliquis prescribing information (US). Health professionals may also consult the Health Canada Drug Product Database entry for apixaban and the FDA label.

You can order from YouDrugstore with confidence. Our licensed pharmacists review prescriptions before dispensing, and we offer prompt, express, cold-chain shipping where needed. We are here to help you keep therapy on track.

Disclaimer: This content is for general information. It does not replace advice from a healthcare professional. Always follow the directions provided by your prescriber and the product labeling.