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Evenity
Price:
$747.30
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Evenity (romosozumab-aqqg) is a monoclonal antibody used to treat osteoporosis in postmenopausal women at high risk of fracture. It works by both increasing bone formation and decreasing bone resorption, helping to significantly improve bone mineral density and reduce the risk of fractures, especially in the spine.
Benefits
- Increases bone density rapidly
- Reduces the risk of spine and other osteoporotic fractures
- Dual action: stimulates bone formation and inhibits bone breakdown
- Administered once monthly for convenience
- Particularly useful in patients who have failed or cannot tolerate other osteoporosis therapies
Dosage
- Recommended dose: 210 mg administered once monthly as two subcutaneous injections of 105 mg each
- Treatment duration is 12 months maximum
- Injections should be given by a healthcare professional
- After completing Evenity, follow-up treatment with an antiresorptive agent (e.g. bisphosphonate) is typically recommended to maintain bone gains
Warnings and Precautions
- May increase the risk of heart attack, stroke, or cardiovascular death—not recommended in patients with a history of recent heart problems
- Hypersensitivity reactions may occur, including rash or angioedema
- May cause hypocalcaemia—correct low calcium levels before starting treatment
- Use with caution in patients with renal impairment, as risk of low calcium is higher
- Not recommended during pregnancy or breastfeeding
- Safety and effectiveness not established in men or in women of reproductive age
Usage Instructions
- Administered as two injections once a month, usually in a medical setting
- Injection sites should be rotated and inspected for signs of reaction
- Ensure adequate intake of calcium and vitamin D during treatment
- Do not miss scheduled doses—contact your provider to reschedule if needed
- Monitor for signs of cardiovascular events or allergic reactions
Storage Information
- Store in the refrigerator at 2°C to 8°C (36°F to 46°F)
- Keep in original carton to protect from light
- Do not freeze or shake
- If removed from refrigeration, may be kept at room temperature (up to 25°C / 77°F) for a single period of up to 30 days
- Discard if not used within 30 days out of refrigeration
Common Side Effects
- Joint pain
- Headache
- Injection site reactions (redness, swelling, or pain)
- Muscle spasms
- Low calcium levels (hypocalcaemia)
- More serious side effects may include cardiovascular events or severe allergic reactions
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