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Invokana® Tablets for Type 2 Diabetes
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Invokana® is a prescription SGLT2 inhibitor used to help manage type 2 diabetes in adults. It lowers blood sugar and supports long-term glucose control under a clinician’s care. Ships from Canada to US with your valid prescription, and it can help if you pay cash or compare Invokana cost without insurance.
What Invokana Is and How It Works
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
Canagliflozin is the active ingredient in this medicine. The canagliflozin generic name refers to the same SGLT2 inhibitor found in the brand. It works in the kidneys to block sodium-glucose cotransporter 2, which reduces glucose reabsorption. More glucose leaves the body through urine, lowering fasting and post-meal blood sugar. This treatment may also reduce the risk of major cardiovascular events and protect kidney function in certain adults with type 2 diabetes and existing risks, according to approved labeling. It is taken by mouth once daily and is intended to be used with diet and exercise.
Who It’s For
This therapy is indicated for adults with type 2 diabetes who need improved glycemic control. It is not for type 1 diabetes or for treating diabetic ketoacidosis. People with severe kidney disease, frequent dehydration, active foot ulcers, or a history of serious lower limb complications may need a different option. Commonly, Invokana used for ongoing management pairs with lifestyle changes and, when appropriate, other antidiabetic medicines. Discuss your medical history, kidney function, and cardiovascular status with a healthcare professional before starting.
Dosage and Usage
Take this medicine once daily, ideally before the first meal of the day. Many adults start at a lower tablet strength, and some may be increased if tolerated and appropriate for kidney function. Your prescriber will use your eGFR and overall risk profile to decide if a higher dose is suitable. Swallow the tablet whole with water. Keep a consistent schedule. Monitor blood glucose as directed and follow individualized nutrition, activity, and foot-care advice from your clinician.
If you use insulin or a sulfonylurea with this SGLT2 inhibitor, your prescriber may monitor closely for low blood sugar. Drink adequate fluids, particularly during hot weather, exercise, or illness. Review sick-day rules with your care team to reduce the risk of dehydration or ketoacidosis.
Strengths and Forms
This product is supplied as oral tablets. Available strengths commonly include Invokana 300mg tablets and a lower tablet option, depending on region and stock. Exact packaging can vary by manufacturer and market. Availability of brand or canagliflozin generics may differ by location and time.
Missed Dose and Timing
If you miss a dose, take it when remembered the same day. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time. Try to take it in the morning, which can align with label guidance to take before the first meal. Use a reminder app or pillbox to support steady daily use.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep the bottle or blister in its original packaging with the label intact. Secure all medicines out of reach of children and pets. For travel, pack an extra small supply, keep medicine in your carry-on, and carry a copy of your prescription. Time-zone changes generally do not require complex adjustments because the dose is once daily; keep to a roughly 24-hour interval and ask your prescriber if unsure. One micro trust cue: encrypted checkout helps protect your information when you order refills.
Benefits
This class can lower A1C when used with diet and exercise. Many people appreciate once-daily dosing and no titration between meals. The therapy may support modest weight and blood pressure changes, although it is not a weight loss medicine. Cardiovascular and kidney outcome benefits apply to certain high-risk adults, per approved indications. It can be combined with other non-insulin and insulin therapies when a prescriber recommends a multi-drug plan.
Side Effects and Safety
- More urination and thirst
- Genital yeast infections
- Urinary tract infections
- Dizziness or lightheadedness
- Constipation or nausea
Serious but less common risks include ketoacidosis, severe urinary infections, Fournier’s gangrene, dehydration with low blood pressure, kidney problems, bone fractures, and lower-limb events. Stop the medicine and get medical help if you develop symptoms of ketoacidosis such as nausea, vomiting, abdominal pain, or unusual fatigue, even with normal blood glucose readings. Hypoglycemia can occur when used with insulin or sulfonylureas; know the signs and how to treat low blood sugar per your care plan.
Drug Interactions and Cautions
Diuretics can increase dehydration and low blood pressure risk. Strong enzyme inducers such as rifampin, phenytoin, carbamazepine, and ritonavir may reduce drug exposure; your prescriber will consider this in your regimen. Monitor kidney function when using ACE inhibitors, ARBs, or NSAIDs. Digoxin levels may increase; monitoring could be needed. Avoid excessive alcohol intake, which can raise the risk of dehydration and ketoacidosis. Tell your healthcare professional about all medicines, supplements, and herbal products you take.
What to Expect Over Time
With consistent daily use, many adults see improved fasting and post-meal glucose. You may notice increased urination soon after starting. Hydration and routine foot care are important parts of ongoing management. Your clinician may check A1C, kidney function, and blood pressure periodically. If you do not meet targets with this therapy alone, your prescriber may adjust your wider diabetes plan. Always follow the official label and your prescriber’s instructions.
Compare With Alternatives
Other SGLT2 inhibitors include Forxiga, which works similarly by increasing urinary glucose excretion. A combination option that pairs canagliflozin with metformin is Invokamet, which may consolidate tablets for some adults. DPP-4 inhibitors, such as sitagliptin, are another class that can be used alone or with metformin when SGLT2 inhibitors are not suitable. Your clinician will select based on your glucose targets, kidney function, and cardiovascular and renal risk profile.
Pricing and Access
Invokana price varies by tablet strength, pack size, and manufacturer. You can review current pricing on the product page and compare options. We provide Canadian pricing with US delivery from Canada for eligible prescriptions. If you are looking for coupons, see current site offers on our Promotions page. Prescription is required and verified before dispensing.
Availability and Substitutions
Supply can change over time. If a particular strength or package is unavailable, your prescriber may recommend a suitable alternative from the same class or a different class based on your clinical needs. Brand and canagliflozin generics may be listed at different times; check the product page for what is currently in stock.
Patient Suitability and Cost-Saving Tips
Adults with type 2 diabetes and adequate kidney function may be candidates. Those with a history of recurrent genital infections, severe peripheral vascular disease, or frequent dehydration should discuss risks carefully. To help manage costs, consider a multi-month fill when appropriate, use refill reminders, and compare brand and generic options. Generic canagliflozin price may differ from the branded product. Explore coverage with your insurer if you submit receipts for reimbursement.
Questions to Ask Your Clinician
- Starting dose plan: what tablet strength and when to take it
- Kidney monitoring: how often to check eGFR and labs
- Hypoglycemia risk: steps if I also use insulin or a sulfonylurea
- Dehydration signs: how to manage fluid intake safely
- Foot care: how to reduce risk of sores or infections
- Sick-day rules: when to hold or call for advice
- Drug interactions: which medicines or supplements to avoid
Authoritative Sources
Manufacturer Prescribing Information
Health Canada Drug Product Database
Learn more about type 2 diabetes in our Type 2 Diabetes and Diabetes Care sections, and explore related reading like Reverse Prediabetes Naturally and Inject Mounjaro. For broader health goals, see Weight Management.
Ready when your prescriber sends a script? Order from YouDrugstore for prompt US shipping from Canada, with temperature-controlled handling when required. Information here is educational and does not replace your clinician’s advice or the official label.
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Can I take canagliflozin with metformin or insulin?
Many adults use this SGLT2 inhibitor with metformin or, when appropriate, with basal or bolus insulin. Combining therapies can improve glucose control but may increase the risk of low blood sugar when insulin or a sulfonylurea is included. Your healthcare professional will tailor your plan and may adjust other medicines. Monitor glucose regularly, carry a fast source of sugar if advised, and report symptoms of hypoglycemia or dehydration promptly.
What are signs of dehydration or low blood pressure on therapy?
Signs can include dizziness when standing, thirst, dry mouth, fatigue, or fainting. These effects can occur because the medicine increases urine output. Drink fluids as directed by your prescriber, be cautious in hot weather, and seek help if you feel unwell. Older adults, those on diuretics, or people with kidney issues may be more sensitive. Report persistent symptoms, especially if you also have vomiting, diarrhea, or fever.
How do I reduce the chance of genital or urinary infections?
Good hygiene, staying hydrated, and changing out of wet clothing quickly can help. Urinate after sexual activity and monitor for early signs like itching, burning, unusual discharge, or urinary discomfort. Contact your clinician if symptoms appear. Recurrent infections may require reassessment of your diabetes plan. Some people benefit from preventive steps tailored by their prescriber based on medical history.
Can this medicine cause ketoacidosis even with normal glucose?
Yes, rare cases of ketoacidosis have occurred, sometimes with blood glucose not as high as expected. Warning signs include nausea, vomiting, abdominal pain, difficulty breathing, and unusual fatigue. Stop the medicine and get emergency care if these occur. Illness, low carbohydrate intake, or heavy alcohol use can raise risk. Your clinician can review sick-day guidance and when to seek urgent help.
Is there an amputation or fracture risk I should know about?
Lower-limb events and bone fractures have been reported. The boxed warning was removed, but careful foot care and prompt attention to sores or infections remain important. Discuss your vascular health, past ulcers, neuropathy, and bone risk factors with your prescriber. They may recommend monitoring, footwear guidance, and strategies to reduce falls and injuries while on treatment.
Do I need to stop before surgery or during acute illness?
Your healthcare professional may advise pausing this therapy before certain surgeries or if you have serious illness, poor intake, or dehydration risk. This can reduce the chance of ketoacidosis. Follow your care team’s instructions for when to hold the tablet and when to restart. Keep emergency contacts handy and let your surgical team know you take an SGLT2 inhibitor.
Can I drink alcohol while taking this SGLT2 inhibitor?
Moderate alcohol may be permissible for some adults, but excess alcohol raises the risk of dehydration and ketoacidosis. Alcohol can also complicate blood sugar control, especially if you use insulin or sulfonylureas. Discuss safe limits with your clinician based on your full medication list, liver health, and diabetes plan. Avoid drinking on an empty stomach and stay hydrated if you choose to consume alcohol.
