Invokana® Tablets for Type 2 Diabetes Management

What Invokana® Is and How It Works

Invokana (canagliflozin) is an oral SGLT2 inhibitor used for adults with type 2 diabetes. It lowers blood sugar by increasing glucose loss in urine. It can also help reduce body weight and blood pressure. Many people compare Invokana cost and Invokana price to manage long-term therapy costs, especially when choosing between 100 mg and 300 mg tablets.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and pharmacists review prescriptions before dispensing. We work with vetted international partner pharmacies to source authentic brand medications, offering a broad selection at competitive Canadian prices.

Invokana is taken once daily, usually before the first meal. It may be used alone or with other diabetes medicines. It also has kidney and cardiovascular outcome data that support use in patients with diabetic kidney disease and existing cardiovascular risks. Invokana pills are available as film‑coated tablets.

Dosage and Usage

• Starting dose: 100 mg by mouth once daily, taken before the first meal.
• Titration: If tolerated and kidney function allows, some patients increase to 300 mg once daily for additional A1C lowering.
• Kidney function: Dosing depends on estimated glomerular filtration rate (eGFR). Lower eGFR may limit dose or use.
• Hydration: Maintain adequate fluid intake to reduce the risk of low blood pressure or dizziness.
• Missed dose: If you miss a dose, take it the same day when remembered. Skip if it is almost time for the next dose. Do not double doses.
• Before surgery or prolonged fasting: Discuss holding the medication as advised by a healthcare professional to reduce ketoacidosis risk.
• Monitoring: Periodic checks of blood sugar, kidney function, and electrolytes may be recommended.
• Tablets: Swallow tablets whole with water. Do not crush or chew.

• Storage: Store tablets at 15–30 °C (59–86 °F) in a dry place.
• Moisture: Keep the bottle tightly closed. Use the desiccant if included.
• Light: Store in the original container to protect from light.
• Travel: Keep medication in carry‑on luggage with the pharmacy label.
• Heat/cold: Avoid leaving tablets in a car or freezing temperatures.
• Pill organizers: If using an organizer, keep it dry and refill weekly.
• Children and pets: Store out of reach in a secure location.

Benefits and Savings

Invokana uses a kidney pathway to reduce glucose reabsorption, which lowers A1C by about 0.6–1.0% on average. Many people also see modest weight reduction, which supports metabolic goals. Some patients experience lower systolic blood pressure due to mild diuresis. For those with diabetic kidney disease and albuminuria, canagliflozin has shown renal protection in clinical studies.

Buying from Canada often lowers the monthly Invokana price. Typical savings are 60–80% compared with common US retail pricing. You can compare Invokana 100mg and Invokana 300mg options, and check canagliflozin price when a generic of Invokana is available in your market. Multi‑month supplies and occasional bulk promotions may further reduce the per‑month cost.

For current offers, see our invokana coupon page.

Side Effects and Safety

• Common: genital yeast infections (thrush), urinary tract infections, increased urination, thirst, dry mouth.
• Digestive: nausea, constipation.
• Circulatory: low blood pressure, dizziness—more likely if dehydrated or on diuretics.
• Skin: rash or itching.
• Lab changes: possible increases in potassium or LDL cholesterol.
• Musculoskeletal: rare reports of fractures.
• Other: fatigue or increased thirst early in treatment.

Serious but uncommon risks include diabetic ketoacidosis (which can occur with near‑normal glucose), severe urinary or genital infections including Fournier’s gangrene, acute kidney injury, and lower‑limb amputation risk noted in earlier trials. Discuss foot care, hydration, and sick‑day plans with a healthcare professional. Hypoglycemia risk increases when combined with insulin or sulfonylureas; a dose reduction of those agents may be considered.

Onset Time

Glucose lowering begins with the first doses as urinary glucose excretion increases. Many people see fasting and post‑meal glucose improvements within 1–2 weeks. A1C changes are typically assessed after 8–12 weeks at a stable dose. Early weight changes may appear within several weeks and continue over a few months. Blood pressure reductions often emerge within the first month.

Compare With Alternatives

Within the SGLT2 class, options include empagliflozin and dapagliflozin. Efficacy for A1C lowering is similar, but study populations and specific cardiovascular or renal indications vary by product labeling. Tablet strengths and kidney dosing thresholds differ across agents.

Some patients use a GLP‑1 receptor agonist instead of, or with, an SGLT2 inhibitor to target greater A1C or weight effects. An injectable example is Victoza® Prefilled Pen, which offers daily dosing and appetite effects that support weight goals.

Others choose a DPP‑4 inhibitor plus metformin combination when SGLT2s are not suitable. A common option is Janumet® XR, which simplifies sitagliptin and metformin into one daily tablet. Your prescriber will match therapy to your A1C target, kidney function, and cardiovascular profile.

Combination Therapy

• Metformin: Frequently paired with Invokana for additive A1C lowering.
• Insulin: May require lowering insulin dose to reduce hypoglycemia risk.
• Sulfonylureas: Consider dose adjustments if low blood sugar occurs.
• GLP‑1 receptor agonists: Complementary effects on weight and glycemia.
• Blood pressure medicines and statins: Commonly used alongside diabetes therapy.
• Diuretics: Monitor for volume depletion and low blood pressure.

Patient Suitability and Cost-Saving Tips

Invokana is for adults with type 2 diabetes who need improved glycemic control. It may be considered in patients with diabetic kidney disease and albuminuria to slow disease progression. It is not for type 1 diabetes or diabetic ketoacidosis. People on dialysis should not use canagliflozin.

Use caution in those with low blood pressure, volume depletion, recurrent genital infections, peripheral vascular disease, prior amputation, or a history of severe urinary infections. Kidney and electrolyte monitoring may be needed. Discuss pregnancy and breastfeeding plans with a healthcare professional, as SGLT2 inhibitors are generally not recommended.

To reduce out‑of‑pocket costs, compare Invokana cost across strengths and quantities. Consider 90‑day fills when appropriate to lower the monthly price. Set reorder reminders so you do not run out. Where available, the Invokana generic name is canagliflozin; comparing canagliflozin price can help when a generic of Invokana is approved in your region. Ask your prescriber to write your Invokana rx for the most cost‑effective strength and quantity you plan to use.

Janssen is the Invokana manufacturer. You can choose brand Invokana medicine or canagliflozin tablets if approved and stocked in your area. We offer fair Canadian pricing and prompt, express shipping to the US.

Authoritative Sources

Janssen Invokana Prescribing Information

Health Canada Drug Product Database: Canagliflozin

FDA Label and Medication Guide for Invokana

Order Invokana® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express delivery.

This content is for educational purposes only and does not replace advice from your healthcare professional.