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Tadalafil (Generic for Cialis®) Uses, Dosing, and Savings
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What Tadalafil Is and How It Works
Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction and urinary symptoms of benign prostatic hyperplasia. It also treats pulmonary arterial hypertension at higher doses. Many people choose to buy tadalafil online for fair, transparent pricing and convenient delivery. A tadalafil prescription is required, and this tadalafil medication is taken by mouth.
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Tadalafil blocks PDE5, which increases cyclic GMP in smooth muscle. In the penis this supports blood flow during sexual stimulation. In the prostate and bladder neck it promotes relaxation and better urine flow. It does not cause arousal and will not work without sexual stimulation.
Onset often begins in 30–60 minutes, with effect lasting up to 36 hours. The medicine is available as tadalafil tablets, including tadalafil 5 mg tablet and tadalafil 20mg tablets. The 40 mg strength is typically used for pulmonary arterial hypertension. Learn more about Erectile Dysfunction and Benign Prostatic Hyperplasia in our condition guides.
Dosage and Usage
- Erectile dysfunction, as needed: 10 mg once before sexual activity; adjust to 5–20 mg based on response and tolerability. Do not exceed one dose per day.
- Erectile dysfunction, daily: 2.5–5 mg once daily at the same time each day.
- Benign prostatic hyperplasia: 5 mg once daily, with or without erectile dysfunction.
- Pulmonary arterial hypertension: 40 mg once daily (usually as two 20 mg tablets). This is a distinct indication and dose.
- Hepatic or renal impairment: lower doses or less frequent use may be required under prescriber direction.
- Food: may be taken with or without food. Avoid heavy alcohol intake, which can worsen dizziness or blood pressure effects.
- Administration: swallow tadalafil pills whole with water. Do not crush or split unless the tablet is scored and directions allow it.
- Missed dose, daily use: take when remembered if the same day; skip if near the next dose. Do not double up.
- Missed dose, as needed use: skip and take the next dose before sexual activity on a different day.
- Drug interactions: do not use with nitrates or guanylate cyclase stimulators (riociguat). Strong CYP3A4 inhibitors (for example, ketoconazole, ritonavir) can raise levels; dose adjustments may be needed.
- Store at 15–25 °C (59–77 °F). Short excursions 15–30 °C (59–86 °F) are acceptable.
- Keep tablets in the original container to protect from moisture and light.
- Do not store in a bathroom or in a hot car. Avoid freezing.
- For travel, carry in hand luggage with a copy of the prescription.
- Keep out of reach of children and pets. Use a child-resistant cap.
Benefits and Savings
Tadalafil offers a long window of action, often up to 36 hours. That allows flexibility for intimacy without tight timing. Daily dosing can smooth erectile function and urinary symptom control across each day. For lower urinary tract symptoms from BPH, many patients see improved flow and less urgency.
Canadian pricing at Youdrugstore helps lower tadalafil cost. Typical savings reach 60–80 % versus many US retail prices. The generic tadalafil 20mg price is often far less than the brand. Multi‑month supplies and bulk promotions can reduce the per‑month tadalafil price. Reorder reminders can help maintain continuity of therapy. If you plan to order tadalafil online, check available pack sizes to lower shipping costs per tablet.
For value comparisons, people often compare tadalafil 20 mg tablet price or tadalafil 5 mg tablet options. Our catalog lists current options clearly so you can choose the strength and quantity that fit your prescription and budget.
Side Effects and Safety
- Headache, flushing, or nasal congestion
- Indigestion or stomach discomfort
- Back pain or muscle aches
- Dizziness or lightheadedness
- Facial redness or warmth
- Vision color tinge or blurred vision
- Runny nose or sinus symptoms
Serious but uncommon effects include prolonged erection (priapism), sudden vision loss (nonarteritic anterior ischemic optic neuropathy), sudden hearing decrease or loss, and severe allergic reactions. Do not combine tadalafil with nitrates in any form, or with riociguat, due to a risk of dangerous hypotension. Use caution with alpha‑blockers or antihypertensives. Discuss cardiovascular history, recent heart attack or stroke, severe liver or kidney disease, eye disorders like retinitis pigmentosa, or conditions predisposing to priapism.
For an in‑depth review, see our guide on Understanding Cialis Side Effects And How To Manage Them and the article Tadalafil Side Effects Common Rare And When To Worry.
Onset Time
When used as needed, many people notice an effect within 30–60 minutes, with peak effect around 2 hours. One dose can remain active for up to 36 hours. With daily dosing, steady‑state levels are reached in about 5 days. BPH urinary symptom relief may progress over 1–2 weeks, with continued improvement over several weeks. For pulmonary arterial hypertension, symptom and walk‑distance changes may take weeks to assess.
Compare With Alternatives
Sildenafil is another PDE5 inhibitor with a 4–6 hour window. It often starts faster, but timing is tighter around sexual activity. Many patients begin with sildenafil and move to tadalafil for longer flexibility. See Viagra® for the branded option or discuss generic sildenafil with your prescriber.
Brand tadalafil, sold as Cialis®, contains the same active ingredient as generic tadalafil. The clinical effect is equivalent when the strength and dosing are the same. Generic options often carry a lower total cost for ongoing therapy.
Combination Therapy
- BPH: tadalafil 5 mg daily may be combined with tamsulosin; start low and monitor blood pressure to reduce dizziness.
- BPH: combining tadalafil with finasteride can help symptom control while finasteride works over months.
- ED with comorbid hypertension: tadalafil may be used with many antihypertensives; dose adjustments can minimize hypotension.
- Avoid: nitrates or riociguat. Do not use together under any circumstance.
- CYP3A4 inhibitors (for example, ritonavir, itraconazole): consider lower tadalafil doses per prescriber guidance.
Patient Suitability and Cost-Saving Tips
Tadalafil is intended for adults. It is not approved for children. It may be suitable for erectile dysfunction, for urinary symptoms of BPH, or for pulmonary arterial hypertension at 40 mg under specialist care. Those with unstable cardiovascular disease, recent MI or stroke, severe hypotension, uncontrolled arrhythmias, or nitrate therapy should not use tadalafil. People with severe liver or kidney disease, penile deformity, bleeding disorders, or certain eye conditions require careful assessment.
Those seeking cheap tadalafil should compare strengths and pack sizes. Larger quantities can cut the per‑tablet cost. The tadalafil 20 mg tablet price and tadalafil cost differ by strength, brand, and quantity. You can buy tadalafil or order tadalafil online after uploading a valid prescription, then select standard or express delivery at checkout. Reorder reminders help avoid gaps, and multi‑month supplies can lower the average monthly cost.
If BPH is the primary concern, discuss daily 5 mg use versus as‑needed dosing for ED. Daily dosing may steady symptom control and simplify routines. For pulmonary arterial hypertension, dosing is distinct at tadalafil 40mg and should be managed by a specialist.
Authoritative Sources
Cialis consumer information (Eli Lilly)
Health Canada Drug Product Database: Tadalafil
FDA Medication Guide for Cialis (tadalafil)
Order Tadalafil from Youdrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.
This material is educational and does not replace advice from your healthcare professional. Always follow your prescriber’s directions and the patient information that comes with your medicine.
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What is tadalafil used for, and how does it work?
Tadalafil is used for erectile dysfunction, urinary symptoms of benign prostatic hyperplasia, and at higher doses for pulmonary arterial hypertension. It blocks PDE5 to increase cGMP in smooth muscle. That helps blood flow in erectile tissue and relaxes the prostate and bladder neck, improving urinary flow and symptoms.
How long does tadalafil last and when should it be taken?
Onset often begins in 30–60 minutes, with peak effect at about 2 hours. One dose may remain effective for up to 36 hours. As‑needed dosing is taken before sexual activity, no more than once daily. Daily dosing uses a lower dose at the same time each day to maintain steady effect.
What is the typical tadalafil dose for ED and BPH?
For ED as needed, 10 mg is common to start, adjusted to 5–20 mg based on response and tolerance. For daily use in ED and BPH, 5 mg once daily is often used. Pulmonary arterial hypertension requires 40 mg once daily. Doses should be individualized by the prescriber and medical history.
Are there important tadalafil safety warnings and interactions?
Do not use tadalafil with any nitrates or with riociguat. This combination can cause dangerous drops in blood pressure. Use caution with alpha‑blockers and antihypertensives. Strong CYP3A4 inhibitors (such as ritonavir or ketoconazole) raise tadalafil levels and may require lower doses. Seek urgent care for priapism, sudden vision loss, or sudden hearing loss.
How much does tadalafil cost and how can I save?
Tadalafil cost varies by strength, brand versus generic, and quantity. Canadian pricing can offer 60–80% savings versus many US pharmacies. Choosing generic tadalafil, comparing pack sizes, and using multi‑month purchases can lower the per‑tablet price. Reorder reminders help avoid rush shipping or last‑minute local purchases at higher prices.
Can I buy tadalafil online and is a prescription required?
Yes. You can buy tadalafil online from a licensed Canadian pharmacy with US shipping. A valid prescription is required. After upload and pharmacist review, your order is dispensed and shipped discreetly. Choosing the right strength and quantity can reduce the per‑tablet price while keeping your therapy consistent and affordable.
Is tadalafil available over the counter?
No. Tadalafil is prescription‑only. Safe use requires evaluation for cardiovascular risk, potential drug interactions, and proper dosing. People using nitrates or riociguat must not take tadalafil. Those with severe liver or kidney disease, recent heart events, or certain eye conditions should be assessed before starting therapy.