Tadalafil (Generic for Cialis®) Tablets for ED and BPH

What Tadalafil Is and How It Works

Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). It comes as oral tablets in multiple strengths. Dosing can be once daily or as needed for ED. Many shoppers compare tadalafil price to plan ongoing therapy.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba and held to Canadian pharmacy standards. Our pharmacists review prescriptions before dispensing to help ensure safe use. Customer-service chat is available during posted office hours for ordering help, and pharmacists can address medication questions through our team.

For ED, tadalafil increases blood flow to the penis during sexual stimulation. For BPH, it relaxes smooth muscle in the prostate and bladder neck and helps ease urinary symptoms. In PAH, it relaxes pulmonary vessels to improve exercise capacity.

We source from licensed, vetted partner pharmacies worldwide so patients can access authentic brands and generics at fair prices across a wide selection.

Dosage and Usage

Dosing depends on the condition, patient profile, and strength prescribed. Follow the prescriber’s instructions on timing and amount.

• ED as needed: Common starting dose is 10 mg taken before sexual activity; adjust based on response and tolerability. Do not take more than once per day.
• ED once daily: 2.5 mg to 5 mg taken at the same time each day, without regard to sexual activity.
• BPH (with or without ED): 5 mg once daily at the same time each day.
• PAH: Often 40 mg once daily (two 20 mg tablets); PAH treatment should be directed by a specialist.
• With food: Tadalafil may be taken with or without food; high-fat meals have minimal effect.
• Missed dose (daily use): If a dose is missed, take it when remembered unless it is near the next dose. Do not double up.

Alcohol can increase dizziness and lower blood pressure. Grapefruit or grapefruit juice may increase tadalafil levels; the prescriber may advise avoidance in some cases.

• Storage at home: Store tablets at 15–30°C (59–86°F) in a dry place. Keep in the original bottle or blister pack and away from moisture.
• Travel: Keep tablets in carry-on luggage. Bring the prescription label. Avoid leaving medicine in a hot car or freezing conditions.
• Disposal: Use local medication take-back options if available.

Benefits and Savings

Tadalafil helps improve erectile function by supporting a natural response to sexual stimulation. It can be taken as needed or once daily, which offers dosing flexibility. For urinary symptoms tied to BPH, daily tadalafil may improve flow and reduce frequency and urgency.

Many people prefer tadalafil for its longer window of effect in ED. On-demand dosing can last up to 36 hours in some patients. Daily dosing provides steady levels and may reduce performance timing pressure.

Ordering through YouDrugstore gives access to Canadian pricing. Typical savings range from 60–80% versus many US retail prices, depending on strength and quantity. Our team supports simple reorders and can send polite reminders before supplies run low.

Side Effects and Safety

Most effects are mild and tend to ease as the body adjusts. Seek urgent care for severe symptoms.

• Common: Headache, flushing, nasal congestion, indigestion, back or muscle pain, and dizziness.
• Less common: Nausea, heartburn, cough, or mild visual color tinge.
• Serious: Priapism (painful erection lasting more than 4 hours), sudden vision loss in one or both eyes, sudden hearing decrease or loss, chest pain, severe allergic reaction, fainting, or signs of stroke.

Do not use tadalafil with any nitrate medicines (nitroglycerin, isosorbide), recreational nitrates, or guanylate cyclase stimulators such as riociguat. The combination can cause dangerous blood pressure drops. Use caution with alpha-blockers and blood pressure medicines; dose adjustments may be required.

People with severe heart disease, recent stroke or heart attack, severe hepatic impairment, uncontrolled hypertension or hypotension, or hereditary degenerative eye disorders should review risks with their prescriber. Kidney or liver impairment may require dose changes.

Onset Time

For ED, tadalafil may start working in 30 minutes, and maximum effect may take up to 2 hours. A single dose can remain effective for up to 36 hours in some patients. With daily dosing for ED or BPH, consistent benefit may build over several days of regular use.

Compare With Alternatives

Tadalafil’s longer duration is a key difference compared with other PDE5 inhibitors. Some patients prefer flexibility over short windows of activity. Others prefer shorter action and dose timing closer to intimacy.

Many patients compare tadalafil with Viagra® and with its generic Sildenafil. Sildenafil tends to act faster for some people, with a shorter duration of effect. High-fat meals can reduce sildenafil’s effectiveness more than tadalafil’s. Tolerability may vary between agents.

Those considering brand may also look at Cialis®. The active ingredient is tadalafil, so clinical effects align with generic tadalafil when used at the same strength and schedule. Brand preference, cost, and availability often guide the choice.

Combination Therapy

For BPH, prescribers sometimes combine tadalafil with other agents such as 5-alpha-reductase inhibitors when symptoms and prostate size warrant it. Combination with alpha-blockers may be considered, but blood pressure should be monitored due to additive effects.

For ED, tadalafil should not be combined with other PDE5 inhibitors. For PAH, do not use tadalafil with another PDE5 inhibitor. PAH regimens may include other classes, such as endothelin receptor antagonists, based on specialist care plans.

Patient Suitability and Cost-Saving Tips

Tadalafil may suit adults with ED seeking either as-needed or daily dosing. It can also help patients with urinary symptoms from BPH. Those with PAH should be managed by specialists experienced with pulmonary vascular disease and drug interactions.

People with significant cardiovascular disease, severe kidney or liver impairment, or those on nitrates or riociguat are not good candidates. Review personal risk factors such as prior episodes of non-arteritic anterior ischemic optic neuropathy or severe vision disorders with the prescriber.

To manage costs, generic tadalafil is often the best value. Larger quantities can reduce the per-month cost, and multi-month fills help avoid supply gaps. Consider a strength that matches the regimen to avoid wasted tablets. We also offer polite reorder reminders to help keep therapy on track.

For current promotions and bulk options, see our tadalafil coupon page. Prices vary by strength and pack size.

If learning about ED or BPH, visit our condition pages for Erectile Dysfunction and Benign Prostatic Hyperplasia for more context. For deeper reading, explore our articles Understanding Cialis Side Effects And How To Manage Them and Tadalafil Side Effects Common Rare And When To Worry.

Authoritative Sources

For official details, review the FDA Prescribing Information for tadalafil, the Health Canada Drug Product Database entry for tadalafil, and the manufacturer’s Cialis (tadalafil) US Prescribing Information.

You can order from YouDrugstore with confidence. We are a licensed Canadian pharmacy with pharmacist review before dispensing and helpful customer-service chat during posted hours. We ship to the US with prompt, express, cold-chain shipping where required.

Content on this page is for general information. It does not replace the advice of a healthcare professional. Always follow the directions provided by the prescriber and the medication label.