Trelegy Ellipta® for Maintenance Treatment of COPD and Asthma

What Trelegy® Ellipta Is and How It Works

Trelegy Ellipta combines three medicines in one dry‑powder inhaler for once‑daily maintenance therapy in adults. It contains fluticasone furoate (an inhaled corticosteroid), umeclidinium (a long‑acting muscarinic antagonist), and vilanterol (a long‑acting beta2‑agonist). It is used for long‑term control of chronic obstructive pulmonary disease and adult asthma, not for sudden breathing problems. Many patients compare trelegy ellipta price when choosing a long‑term inhaler.

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Each component plays a distinct role. Fluticasone reduces airway inflammation and swelling. Umeclidinium blocks M3 receptors to relax airway smooth muscle and reduce mucus tone. Vilanterol stimulates beta2 receptors to further open the airways. The once‑daily dosing supports adherence and consistent symptom control.

Trelegy Ellipta is indicated for maintenance treatment of COPD, including chronic bronchitis and emphysema. It also treats asthma in adults who need triple therapy. For disease education, see Chronic Obstructive Pulmonary Disease.

Available strengths include 100/62.5/25 micrograms and 200/62.5/25 micrograms of fluticasone furoate/umeclidinium/vilanterol per inhalation. COPD patients typically use the 100 strength. Some adults with asthma may use the 200 strength based on control needs. Do not use to relieve acute bronchospasm; a rapid‑acting rescue inhaler remains necessary.

Dosage and Usage

• Usual dose: one inhalation once daily, at the same time each day. Do not take more than one inhalation in 24 hours.
• Asthma strength selection may be adjusted by the prescriber between 100/62.5/25 and 200/62.5/25 based on control.
• Missed dose: skip the missed dose and take the next dose at the usual time. Do not double the dose.
• Rinse the mouth with water and spit after each dose to reduce the risk of oral thrush.
• Ellipta device steps: open the cover fully until a click is heard; exhale away from the mouthpiece; place mouthpiece between lips and inhale steadily and deeply; remove inhaler and hold breath for several seconds; breathe out slowly; close the cover.
• Do not block the air‑vent or shake the device. Do not wash the inhaler; keep it dry.

• Store unopened inhaler in the foil tray at room temperature (20–25 °C; 68–77 °F); short trips between 15–30 °C (59–86 °F) are acceptable.
• After opening the tray, write the opening date on the label. Discard 6 weeks after opening or when the counter reads 0, whichever comes first.
• Keep the device dry. Avoid bathrooms with high humidity.
• When traveling, keep your inhaler in your carry‑on. Use a hard case to prevent crushing.
• Protect from extreme heat or cold. Do not freeze. Do not store in a car glovebox.
• Bring a backup rescue inhaler and a copy of your prescription when you travel.

Benefits and Savings

Trelegy Ellipta simplifies therapy by delivering triple action in one daily inhalation. Patients often see better lung function, improved breathlessness scores, and fewer COPD exacerbations versus dual therapy. For asthma, stepping up to Trelegy can reduce symptoms and rescue inhaler use when dual therapy is not enough.

Convenience matters for adherence. A single device can replace separate controller inhalers. The counter helps track remaining doses, and the dry‑powder format does not require coordination with a propellant spray. Many patients value this simplicity when comparing trelegy inhaler options.

Ordering from Canada can mean meaningful savings. Typical customers save 60–80% compared with US retail, depending on strength and pack size. You can review trelegy price and the price of trelegy ellipta by strength on each product page. Multi‑month supplies and periodic bulk promotions may reduce the per‑month cost.

For current offers, see our trelegy coupon page.

Side Effects and Safety

• Common effects: headache, sore throat, hoarseness or voice changes, cough, nasal congestion, and back pain.
• Oral thrush (white patches), mouth irritation, or tongue pain due to the corticosteroid component.
• Tremor, nervousness, or palpitations related to the LABA component.
• Dry mouth, constipation, or blurred vision related to the LAMA component.
• Upper respiratory infections or bronchitis.
• Muscle cramps or joint pain.

Serious risks are uncommon but can include pneumonia in COPD, paradoxical bronchospasm, severe allergic reactions, adrenal suppression, reduced bone mineral density, glaucoma or cataracts, and urinary retention. Use caution in patients with cardiovascular disease, seizure disorders, hyperthyroidism, narrow‑angle glaucoma, prostatic hyperplasia, or milk protein allergy (lactose‑containing powder). Do not start or stop therapy without prescriber guidance.

Onset Time

Bronchodilation from vilanterol begins within the first dosing day. Some people notice easier breathing within hours. Symptom control usually improves over 1–2 weeks as inflammation decreases. Exacerbation reduction is best assessed over several months of consistent use.

Rescue relief remains essential for sudden symptoms. Trelegy Ellipta does not treat acute bronchospasm. For background reading on COPD care, see Treatment And Medications For Acute And Chronic Bronchitis And Copd.

Compare With Alternatives

Some patients do well on dual therapy and may not need triple therapy. Breo Ellipta (fluticasone/vilanterol) offers ICS/LABA in a similar device but lacks the LAMA component. Anoro Ellipta (umeclidinium/vilanterol) offers LAMA/LABA but no steroid. Your prescriber will match therapy to disease severity and history of exacerbations.

For steroid‑only maintenance in asthma, Flovent® Diskus is an option and uses a different dry‑powder device. For LAMA monotherapy in COPD, Spiriva® Handihaler Refills provide tiotropium capsules for inhalation with a handihaler device.

Device technique also matters. Patients who struggle with dry‑powder inhalation may be better suited to a metered‑dose inhaler or a nebulized controller, as guided by a clinician.

Combination Therapy

• Keep a short‑acting bronchodilator (e.g., albuterol/salbutamol) for rescue use as directed.
• Avoid adding another LABA or LAMA alongside Trelegy Ellipta to prevent duplication and side effects.
• In select COPD cases, prescribers may add roflumilast or macrolide prophylaxis for exacerbation reduction.
• Vaccinations (influenza, pneumococcal) are part of comprehensive COPD care.
• Pulmonary rehabilitation and smoking cessation support overall control.

Patient Suitability and Cost-Saving Tips

Trelegy Ellipta is for adults who need maintenance control of COPD or asthma. It is not for children. It should not be used to relieve acute symptoms. It is not appropriate for patients with severe milk protein allergy or those who cannot use a dry‑powder device reliably.

Use caution in patients with narrow‑angle glaucoma, urinary retention, osteoporosis, eye disorders, or serious heart rhythm problems. Those with frequent infections or on systemic steroids need monitoring for adrenal suppression and infection risk. Report worsening breathing, vision changes, or signs of pneumonia promptly.

You can set gentle reorder reminders to avoid gaps in therapy. Ordering a 2–3 month supply can lower the effective monthly price. Many patients compare trelegy ellipta cost, trelegy cost with insurance, and out‑of‑pocket options before deciding. Pharmacy pricing does not include local taxes or carrier fees where applicable.

Authoritative Sources

See the manufacturer information on the GSK Trelegy patient site for device instructions and safety.

Refer to the Health Canada Drug Product Database for Canadian product listings.

Review the FDA Prescribing Information for full US labeling details.

Order Trelegy® Ellipta from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express shipping.

This page is educational and does not replace advice from your healthcare professional. Always follow your prescriber’s instructions and the patient information that comes with your medicine.