Trelegy Ellipta® Inhaler for COPD and Asthma

This prescription inhaler combines three medicines to help control COPD and asthma symptoms long term. This page explains how it works, who it’s for, and how to use it correctly so you can discuss it with your clinician and plan your refills.

What Trelegy Ellipta Is and How It Works

YouDrugstore provides US shipping from Canada, including options if you are paying without insurance. Trelegy Ellipta® is a once-daily dry powder inhaler that delivers three active ingredients: an inhaled corticosteroid, a long-acting muscarinic antagonist, and a long-acting beta2-agonist. Together, they help reduce airway inflammation, relax airway muscles, and improve airflow for maintenance control. A Fluticasone umeclidinium vilanterol inhaler combines these classes in one device to simplify ongoing therapy.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

The Ellipta device is breath-actuated. Opening the cover loads one dose and sets the counter. Inhaling steadily draws the powder into your lungs. It is not a rescue inhaler and will not relieve sudden breathing problems; keep a fast-acting reliever on hand as directed by your prescriber.

Who It’s For

This treatment is indicated for the long-term maintenance of airflow obstruction and to reduce exacerbations in adults with COPD. It is also approved for maintenance treatment of asthma in adults who need combination control. A Fluticasone umeclidinium and vilanterol option may be considered when symptoms remain despite other controllers. It should not be used to treat acute bronchospasm. People with severe milk protein allergy should avoid this inhaler. Discuss your history of glaucoma, urinary retention, heart rhythm issues, osteoporosis, or infections with your healthcare professional.

Dosage and Usage

Trelegy Ellipta dosage is typically one inhalation once daily at the same time each day. Do not use it more often than prescribed.

• Prepare dose: open the cover fully until it clicks. The counter will decrease by one.
• Exhale away: breathe out fully, away from the mouthpiece.
• Inhale: seal lips around the mouthpiece and take one long, steady, deep breath in.
• Hold breath: hold for about 3 to 4 seconds, then breathe out slowly.
• Rinse: spit out water after rinsing your mouth to reduce the chance of oral thrush.

Do not block the air vent, and do not shake the device. If symptoms worsen or you need your reliever more often, contact your prescriber. Always follow the official Patient Information and your clinician’s instructions.

Strengths and Forms

The Ellipta device contains 30 pre-metered doses. Commonly available strengths pair three components in fixed combinations, such as 100/62.5/25 mcg and 200/62.5/25 mcg per inhalation. Availability may vary by location and stock.

Missed Dose and Timing

If you miss a dose, take your next dose at the usual time. Do not take two doses at once. Aim for consistent daily timing. Morning use may help you remember, but choose a time that fits your routine.

Storage and Travel Basics

Keep the inhaler sealed in its tray until first use. After opening the tray, write the date on the label, keep the cover closed when not in use, and use within the period stated in the Patient Information. Store at room temperature in a dry place, away from excessive heat and moisture. Do not wash the mouthpiece; wipe it with a dry tissue if needed. Keep out of reach of children and pets.

For travel, carry it in your hand luggage with the prescription label. Bring a copy of your prescription if you are crossing borders. Avoid leaving the device in a hot car. Track the dose counter and plan refills before you run low. Learn more about the conditions it treats in our guides on COPD and Asthma, and explore our Respiratory treatments.

Benefits

This medicine may simplify your routine by combining three long-acting therapies in one inhaler. Once-daily dosing can support consistent use. The device has a clear dose counter and is breath-actuated, which may reduce coordination steps. For some adults who remain symptomatic on dual therapy, triple therapy can offer a more complete maintenance approach as outlined in clinical guidelines.

Side Effects and Safety

• Upper respiratory tract infection
• Headache or back pain
• Sore throat, hoarseness, cough
• Oral thrush or mouth irritation
• Sinus infection or runny nose
• Muscle cramps or joint pain

Serious but less common risks can include pneumonia in COPD, paradoxical bronchospasm, allergic reactions, effects on heart rhythm or blood pressure, eye pressure changes, bone density effects, adrenal suppression with high exposure, and urinary retention. The risk of hypokalemia may increase when combined with certain medicines. This is not a rescue inhaler. Seek urgent care for severe breathing problems, chest pain, swelling of the face or throat, or signs of infection with fever and worsening cough.

If you experience bothersome effects or new symptoms, contact your prescriber or pharmacist. Review the Patient Information for a full list of risks and precautions.

Some people may read about a Trelegy Ellipta medication causing oral thrush; rinsing and spitting after each dose can help reduce this risk.

Drug Interactions and Cautions

Tell your healthcare professional about all medicines you take. Interactions can occur with strong CYP3A4 inhibitors (such as ritonavir or ketoconazole), which may increase steroid exposure. Combining with other long-acting bronchodilators may raise side-effect risks. Beta blockers can blunt bronchodilator effects. Diuretics that lower potassium, MAO inhibitors, tricyclic antidepressants, and certain macrolide antibiotics may require caution. Use care if you have narrow-angle glaucoma or urinary retention. Do not use with other inhalers containing a LABA or LAMA unless directed by your prescriber.

For general education on airway diseases, see Acute Bronchitis and What Is Asthma.

What to Expect Over Time

With regular daily use, many people notice easier breathing and fewer day-to-day symptoms over time. Exacerbation risk may change based on adherence, inhaler technique, and other factors. You may still need a rescue inhaler for sudden symptoms. Track your inhalations and keep notes on cough, wheeze, and activity tolerance. Share these details during follow-ups so your clinician can assess control and adjust your plan if needed.

Compare With Alternatives

Several maintenance options may be considered based on your history and spirometry. An ICS/LABA combination such as Breo® Ellipta may suit adults controlled on dual therapy. A LAMA/LABA such as Anoro® Ellipta Inhaler provides two bronchodilators without an inhaled steroid. A LAMA-only option like tiotropium (for example, Spiriva) may be used in certain cases. Your clinician will determine which class aligns with your diagnosis, symptoms, and exacerbation risk.

Pricing and Access

Compare Trelegy Ellipta price with Canadian pharmacy rates and transparent checkout. We provide Ships from Canada to US fulfilment with prescription verification. Review current pricing and place your order when your prescriber has sent your script. For seasonal offers, see our Promotions. Our encrypted checkout helps protect your information.

Availability and Substitutions

Supply can vary by strength. If your preferred strength is unavailable, your prescriber may recommend an alternative combination or a different maintenance class. The Trelegy Ellipta generic name is fluticasone furoate/umeclidinium/vilanterol; at this time, authorized generics may not be available in all markets. Do not change your regimen without speaking to your clinician.

Patient Suitability and Cost-Saving Tips

This inhaler may be suitable for adults diagnosed with COPD or asthma who need ongoing control with multiple classes. It is not appropriate for sudden breathing problems or for people with severe milk protein allergy. Those with uncontrolled glaucoma, urinary retention, certain heart rhythm conditions, or active infections should review risks closely with their prescriber.

• Multi-month supply: ask about 60- or 90-day fills to reduce per-fill costs.
• Technique check: proper inhalation helps each dose work as intended.
• Set reminders: use phone alerts or calendars to keep dosing consistent.
• Refill planning: start reordering when the counter shows about one week left.
• Travel ready: pack a backup reliever and keep your controller in carry-on.

Questions to Ask Your Clinician

• Is triple therapy appropriate for my COPD or asthma history?
• Which strength matches my current control and risk profile?
• How should I coordinate this inhaler with my rescue medicine?
• What signs suggest I should schedule a follow-up sooner?
• Do any of my medicines raise interaction risks with this inhaler?
• What technique tips can improve delivery with my device?

Authoritative Sources

FDA Prescribing Information

DailyMed: Trelegy Ellipta

Health Canada Drug Product Database

Ready to proceed? Order from YouDrugstore for US delivery from Canada with prompt shipping and temperature-controlled handling when required. This page is for general information and does not replace medical advice from your clinician.