Latanoprost/Timolol Ophthalmic Solution – Xalacom® Generic Details and Use

What Latanoprost/Timolol Is and How It Works

Latanoprost/Timolol Ophthalmic Solution combines two glaucoma medicines in one bottle. It helps lower high eye pressure in open‑angle glaucoma and ocular hypertension. Many people search for Latanoprost/Timolol eye drops without insurance to manage ongoing costs, and this fixed‑dose option can help streamline therapy. You take it as prescribed by your eye care professional.

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How it works: latanoprost is a prostaglandin analogue that increases uveoscleral outflow of aqueous humor. Timolol is a non‑selective beta‑blocker that reduces aqueous humor production. Together, they lower intraocular pressure (IOP) more than either agent alone for many patients. The solution is for ophthalmic use only. Most regimens use one drop in the affected eye(s) once daily, typically in the evening.

Dosage and Usage

• Use exactly as prescribed: usually 1 drop in the affected eye(s) once daily in the evening.
• Wash and dry your hands.
• Remove contact lenses before use; wait 15 minutes before reinsertion.
• Shake the bottle gently if directed on your label.
• Tilt your head back, pull down the lower eyelid to create a small pocket.
• Hold the dropper above the eye; avoid touching the tip to any surface.
• Instill 1 drop into the pocket. Do not exceed once daily dosing.
• Close your eye gently; press the inner corner of your eye (punctal occlusion) for 1–2 minutes.
• If using other eye drops, wait at least 5 minutes between products.
• Missed dose: apply when remembered unless it is near the next dose. Do not double the dose.
• Do not wear soft contact lenses during instillation; benzalkonium chloride can be absorbed by lenses.
• Discard the bottle by the expiry or the directed in‑use time, even if solution remains.

• Store unopened bottles in the refrigerator at 2–8 °C (36–46 °F). Do not freeze.
• After opening, many products may be stored at room temperature up to 25 °C (77 °F) for up to 4 weeks; follow your label’s in‑use period.
• Keep the cap tightly closed. Protect from light.
• For travel, use an insulated pouch with ice packs to maintain 2–8 °C for unopened bottles.
• Do not leave drops in a hot car or direct sun.
• If exposed briefly to warmer temperatures, return to recommended storage as soon as possible.
• Keep out of reach of children and pets.

Benefits and Savings

This fixed‑combination drop can simplify your routine. One daily dose may replace two separate bottles, which can improve adherence. The dual mechanism often provides greater IOP reduction than either component alone. Many patients find fewer bottles easier to manage, especially when coordinating morning and evening schedules.

Buying through a Canadian pharmacy can reduce your monthly spend. Typical savings are 60–80% versus common US prices, depending on the Latanoprost/Timolol Ophthalmic Solution price and supply size. Multi‑month supplies and bulk promotions can lower the per‑month cost further. If you pay out of pocket or prefer Latanoprost/Timolol without insurance, transparent pricing helps you plan refills.

Ask about deals before checkout. You can review current offers with a single click on our Latanoprost/Timolol coupon page.

We ship to the US with prompt, express handling, using cold‑chain methods where required to protect temperature‑sensitive eye drops.

Side Effects and Safety

• Eye irritation, burning, stinging, or itching
• Conjunctival redness
• Dry eye, watery eyes, or foreign‑body sensation
• Temporary blurred vision after instillation
• Eyelash growth or thickening
• Darkening of the iris, eyelids, or eyelashes
• Headache
• Taste changes
• Systemic beta‑blocker effects such as fatigue, slow heart rate, or low blood pressure
• Respiratory symptoms in sensitive individuals (e.g., wheeze)

Serious but less common risks include asthma or COPD exacerbation, heart block, symptomatic bradycardia, severe hypotension, corneal changes, and allergic reactions. Timolol may mask signs of low blood sugar in people with diabetes. Use caution if you also take oral beta‑blockers or have a history of cardiac conduction problems, reactive airway disease, or severe heart failure. Pigmentation changes from prostaglandins may be permanent.

Onset Time

IOP lowering begins within hours. Timolol’s effect often starts within 1 hour and peaks around 2–4 hours. Latanoprost’s effect begins within 3–4 hours and peaks by 8–12 hours. Most people see meaningful pressure reductions within the first week. The full response may stabilize over 2–4 weeks as your dosing routine settles. Keep using the drops as directed, even if your eyes feel normal.

Compare With Alternatives

Some patients use a single‑agent prostaglandin first. Latanoprost alone is a common choice. If once‑daily monotherapy keeps IOP at goal, combination therapy may not be needed. You can compare coverage and dosing by reviewing Xalatan® Ophthalmic Solution, which contains latanoprost only.

Another option is bimatoprost. It is also once daily and may offer strong IOP reduction with a similar side‑effect profile. See Lumigan® Rc for details on that prostaglandin.

Alpha‑agonists such as brimonidine (e.g., Alphagan) and carbonic anhydrase inhibitors like dorzolamide are also used. These may be added to, or substituted for, other therapies based on response and tolerability. Your prescriber will tailor a plan to reach your target IOP with the fewest drops needed.

Combination Therapy

• With brimonidine: often dosed two or three times daily; separate drops by at least 5 minutes.
• With dorzolamide: may be used two or three times daily; apply this combination once daily as directed.
• Oral acetazolamide: sometimes used short‑term for rapid IOP control; monitor closely.
• Avoid using two prostaglandins together unless your prescriber instructs otherwise.
• If you also take systemic beta‑blockers, your prescriber may adjust doses to reduce bradycardia risk.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults with open‑angle glaucoma or ocular hypertension who need greater IOP reduction or fewer bottles. It is not ideal for people with certain heart rhythm problems, severe asthma or COPD, cardiogenic shock, or decompensated heart failure. Use caution in diabetes and hyperthyroidism because timolol can mask symptoms. Discuss use in pregnancy or breastfeeding with your clinician.

Contact lens wearers should remove lenses before dosing and wait 15 minutes before reinsertion. Tell your prescriber about past eye infections, herpetic keratitis, or eye surgeries. Report new breathing issues, slow pulse, dizziness, or persistent eye pain promptly.

To manage the Latanoprost/Timolol 0.005/0.5 cost, consider larger fills when appropriate. Multi‑month supplies can reduce the per‑bottle price. Set reorder reminders so you do not run out. Bulk promotions may be available at checkout. If you pay the Latanoprost/Timolol cash price, comparing the Latanoprost/Timolol generic cost to brand options can help plan your out‑of‑pocket budget. This also supports those needing Latanoprost/Timolol no insurance.

Authoritative Sources

Health Canada Drug Product Database: latanoprost/timolol entries

DailyMed: latanoprost ophthalmic solution labeling

DailyMed: timolol maleate ophthalmic solution labeling

Order Latanoprost/Timolol Ophthalmic Solution from Youdrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold‑chain handling.

This page is educational and does not replace advice from your healthcare professional. Always follow your prescriber’s directions and your pharmacy label.