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Xalacom® Ophthalmic Solution for Open-Angle Glaucoma
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Latanoprost/timolol eye drops lower pressure inside the eye. This combination is used in adults with open-angle glaucoma or ocular hypertension. You can access it with US delivery from Canada, including options for latanoprost timolol without insurance.
What Xalacom® Is and How It Works
Xalacom® combines two medicines in one bottle. Latanoprost is a prostaglandin analog that helps fluid leave the eye more easily. Timolol is a beta blocker that decreases fluid production in the eye. Together, they reduce intraocular pressure when one agent alone is not enough.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This therapy is intended to reduce the risk of optic nerve damage caused by high pressure. It is typically taken long term under a prescriber’s supervision. If your clinician has prescribed an additional drop, separate products by several minutes to limit washout.
Latanoprost/timolol is part of a well-studied class of glaucoma treatments. The combination can simplify routines for people using more than one ingredient to control pressure.
Who It’s For
The combination is indicated to reduce elevated intraocular pressure in adults with open-angle glaucoma or ocular hypertension. It may be appropriate if a single agent has not achieved target pressure. Some patients use it as an alternative to separate bottles when convenience is important.
People with asthma, severe COPD, certain heart rhythm problems, a slow heart rate, or uncontrolled heart failure should avoid beta blockers unless a prescriber decides the benefit outweighs risk. Those with a history of herpetic keratitis or uveitis should use prostaglandin analogs cautiously. If you wear contact lenses, remove them before dosing and wait 15 minutes before reinsertion.
Ask your prescriber if this option suits your condition. Our Open Angle Glaucoma and Ocular Hypertension pages offer added background.
Dosage and Usage
Use one drop in the affected eye or eyes once in the evening, unless your prescriber directs otherwise. Do not use it more than once daily, since extra doses may reduce the pressure‑lowering effect. If your regimen includes other eye medicines, wait at least five minutes between products.
Wash your hands. Tilt your head back and gently pull down the lower lid. Place one drop into the pocket without touching the tip to your eye or skin. Close your eye and press the inner corner for one to two minutes to limit systemic absorption. Replace the cap tightly after use.
If you wear soft contact lenses, remove them before dosing. Many bottles contain benzalkonium chloride, which can be absorbed by soft lenses. Reinsert after 15 minutes. Follow your prescriber’s plan for follow-up pressure checks and monitoring.
Some people ask about frequency. The labeled schedule supports latanoprost timolol once daily. More frequent dosing is not advised unless your clinician alters the plan.
Strengths and Forms
This combination is supplied as a sterile ophthalmic solution in multi-dose bottles. Common presentations include latanoprost 0.005% with timolol 0.5% per mL. Availability, brands, bottle sizes, and preservatives can vary by manufacturer and country.
When selecting a product, consider preservative content and prescriber guidance. If a preservative-free option is needed, your clinician can advise on suitable choices.
Some patients who cannot tolerate beta blockers may instead use a prostaglandin analog alone. See our Ophthalmology category for related options.
Missed Dose and Timing
If you miss a dose, apply the next dose at the usual time on the following day. Do not double up to catch up. Keep a consistent evening routine to support adherence and pressure control.
When using multiple eye medicines, spacing them by several minutes helps prevent dilution. If irritation occurs, pause and try again later that day. Contact your prescriber if problems continue.
Storage and Travel Basics
Keep bottles in the original carton to protect from light. Follow the label for unopened and after‑opening storage. Some versions are kept refrigerated before first use and then stored at room temperature for a limited time after opening. Check your specific packaging and pharmacy label for the exact guidance.
Do not freeze the solution. Keep out of reach of children and pets. If traveling, carry the bottle in hand luggage and avoid extreme temperatures. Bring your prescription or a copy of your label if you cross borders. Our systems use encrypted checkout, and temperature-controlled handling when required.
Benefits
This medicine offers a complementary dual mechanism within one bottle. A single evening dose can simplify care compared with two separate products. Many people appreciate fewer containers, fewer caps to open, and a streamlined routine. The treatment may help you achieve target intraocular pressure under your prescriber’s plan.
For some, the combination also reduces exposure to extra preservatives by consolidating therapy. Using one product may help with adherence, which supports sustained pressure lowering over time.
Side Effects and Safety
Common effects include mild eye irritation, burning, stinging, redness, itching, blurred vision, dry eye, or a sensation of a foreign body. Eyelid skin may darken and eyelashes may grow longer or thicker with continued use. The iris can gradually darken in some patients. Report eye pain, persistent redness, vision changes, or signs of infection.
Timolol, a beta blocker, can be absorbed and may affect the heart or lungs. Possible systemic effects include slow heart rate, low blood pressure, fatigue, shortness of breath, or worsening asthma. Rare reactions include severe allergic responses or corneal issues linked to contaminated droppers.
Review the leaflet before use. Seek urgent care if you notice breathing problems, fainting, chest pain, or a severe rash. This section discusses general information; it does not replace your prescriber’s advice. The phrase latanoprost timolol side effects refers to the above common and serious concerns.
If seasonal symptoms complicate eye comfort, learn more from this general resource: Claritin Allergy Medicine.
Drug Interactions and Cautions
Tell your clinician about all medicines you take. Using oral beta blockers or calcium channel blockers together with this drop can increase the chance of slowed heart rate or low blood pressure. Combining with other prostaglandin analogs is not recommended. Discuss digoxin, clonidine, and adrenergic agents as well.
Diabetes and thyroid disorders can affect how you sense low blood sugar or heart rate changes when beta blockers are involved. People with severe circulation issues should use caution. Remove contact lenses before dosing and wait 15 minutes before reinserting. This overview touches the key latanoprost timolol interactions that clinicians usually check.
What to Expect Over Time
Most people continue this treatment long term. Your prescriber will check intraocular pressure and optic nerve health at follow-up visits. Adherence matters. Try pairing your dose with an evening routine like brushing teeth. Keep a simple log if you miss doses frequently.
Visible changes such as eyelash growth or gradual iris darkening may appear with ongoing prostaglandin use. These cosmetic effects may persist even if therapy stops. If you experience eye discomfort or new symptoms, contact your prescriber for guidance.
If you need a single-agent prostaglandin at some point, options exist such as Latanoprost Ophthalmic Solution and others. Discuss whether a change would fit your pressure targets and tolerance.
Compare With Alternatives
Some patients do well with a single prostaglandin analog. One option is Xalatan® Ophthalmic Solution, which contains latanoprost alone. Others may need a carbonic anhydrase inhibitor plus a beta blocker in one bottle, such as Dorzolamide Timolol Ophthalmic Solution. Your prescriber will match therapy to pressure goals and your medical history.
Pricing and Access
Canadian pricing may offer value compared to typical cash-pay options. Check our current listings for your bottle size and manufacturer. If you look for a specific preservative profile, review the product details before checkout. For savings news and seasonal offers, see our Promotions page.
We provide secure checkout and prescription validation. Orders are filled by our pharmacy and Ships from Canada to US. If you have questions about self-pay approaches or flexible fills, contact our team. We can also discuss refill timing so you never run short.
Availability and Substitutions
Supply may vary by manufacturer and bottle size. If a specific version is unavailable, your prescriber may suggest a clinical alternative in the same class or a compatible regimen using separate products. We will dispense the product on your prescription when in stock or coordinate an appropriate substitution with your clinician’s approval.
Patient Suitability and Cost-Saving Tips
This combination may suit adults who need dual therapy to reach pressure goals. It may not be appropriate for people with reactive airway disease, certain cardiac conditions, or those who have not tolerated beta blockers. Discuss risks and benefits if pregnant, planning pregnancy, or breastfeeding.
- Multi-month fills: Ask about longer supplies if your prescription allows.
- Set reminders: Use a phone alarm at your usual evening time.
- Travel-ready: Pack an extra bottle when traveling long distances.
- Lens routine: Dose before inserting contacts each day.
- Budget planning: Compare options and discuss generic choices with your prescriber.
If you need another option in the same therapeutic area, you can also review Azopt under your prescriber’s guidance.
Questions to Ask Your Clinician
- Is this combination right for my type of glaucoma and target pressure?
- How should I space this product with any other drops I use?
- What symptoms suggest a reaction that needs prompt medical attention?
- Are there heart or lung conditions that make this product unsafe for me?
- Could a single-agent prostaglandin or a different combination be suitable later?
- How often should I return for pressure checks and optic nerve exams?
Authoritative Sources
Xalacom Product Monograph (Pfizer Canada)
DailyMed: Timolol Ophthalmic (reference)
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Can I use these drops with contact lenses?
Yes, but remove soft lenses before each dose. Many bottles contain benzalkonium chloride, which can be absorbed by lenses and may irritate the eye. Apply one drop, then wait at least 15 minutes before reinserting lenses. If your eyes feel dry or irritated, discuss preservative-free options with your prescriber. Always avoid touching the dropper tip to your eye or any surface to keep the solution sterile.
Will my eye color change while using this medicine?
Prostaglandin analogs can gradually increase brown pigment in the iris of some patients, particularly those with mixed-color irides. This cosmetic change may be permanent. Eyelash growth and eyelid skin darkening can also occur with continued use. These effects usually do not affect vision. If you notice rapid changes, new eye pain, or vision symptoms, contact your healthcare professional for guidance.
What if I forget a dose?
If you miss a dose, apply the next dose at your regular time the following day. Do not use extra drops to make up for a missed dose. Try pairing your dose with a nightly routine, like brushing your teeth, to stay consistent. If you frequently miss doses, ask your prescriber about reminders or tools that can fit your schedule.
Which medicines may interact with this treatment?
Tell your prescriber about all medicines and supplements. Oral beta blockers, some calcium channel blockers, and digoxin can increase the risk of slowed heart rate or low blood pressure when used with this drop. Using another prostaglandin analog at the same time is generally not advised. Share your history of asthma, COPD, or heart problems so your clinician can review safety.
How should I store the bottle at home and when traveling?
Keep the bottle in its carton to protect from light. Follow your label for storage before and after opening, as some versions are kept cold before first use. Do not freeze. When traveling, carry the medicine with you, avoid temperature extremes, and keep it away from children. Bring your prescription or a copy of the label to help with security checks.
Can I use it if I have asthma or heart issues?
This product contains a beta blocker, which can affect the heart and lungs. People with asthma, severe COPD, slow heart rate, certain rhythm disorders, or uncontrolled heart failure may not be candidates. Your prescriber will weigh benefits and risks. Share your full medical history, including breathing problems and heart conditions, before starting therapy.
How long will I need to use the drops?
Glaucoma and ocular hypertension are typically long-term conditions. Most patients continue therapy to keep eye pressure at target levels and reduce the risk of optic nerve damage. Your clinician will schedule regular pressure checks and eye exams. If your goals are not met or side effects occur, your regimen may be adjusted or an alternative may be recommended.
