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Metrogel® (Metronidazole) Topical Gel 0.75% and 1% for Rosacea
Price range: $60.99 through $263.99
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What Metrogel® Is and How It Works
Metrogel® is a topical form of metronidazole used for rosacea. It helps reduce inflammatory bumps, pustules, and facial redness. The 0.75% gel is usually applied twice daily, and the 1% gel is applied once daily. Metrogel is for skin use only. It is not the same as the vaginal metronidazole gel used for bacterial vaginosis.
YouDrugstore is a licensed Canadian pharmacy based in Manitoba. Pharmacists review each prescription before dispensing. You can order online at Canadian prices, and our team offers friendly customer-service chat during posted hours.
Metronidazole reduces inflammation in the skin. It lowers reactive oxygen species and calms neutrophil activity. It may also affect skin microbes linked to rosacea. These actions help reduce redness and breakouts over several weeks.
We source medicines through licensed, vetted partner pharmacies to provide authentic brands and a broad selection at fair prices. Many customers compare metrogel price for value, and choose longer supplies for added convenience.
This page refers to the external skin gel for rosacea and related facial conditions. The vaginal gel is a separate product with different instructions and uses.
Dosage and Usage
Follow your prescriber’s directions and the product leaflet. Typical regimens:
- 0.75% gel: apply a thin layer to affected areas twice daily.
- 1% gel: apply a thin layer to affected areas once daily.
- Gently cleanse and pat dry skin before application.
- Use a pea-sized amount for each facial region as needed.
- Allow the gel to dry before applying cosmetics or sunscreen.
- If irritation develops, seek guidance on adjusting frequency.
Missed dose and general tips:
- If a dose is missed, apply when remembered. If it is near the next dose, skip the missed dose. Do not double up.
- Avoid eyes, inside the nose, and mouth. Rinse with water if contact occurs.
- Do not apply to broken skin unless directed by your prescriber.
Storage and travel:
- Store your gel at room temperature, about 20–25°C (68–77°F).
- Protect from freezing. Keep the cap closed tightly.
- When you travel, carry your medication in your hand luggage.
- Keep out of reach of children and pets.
Benefits and Savings
Metrogel® helps reduce inflammatory lesions of rosacea. Many people see fewer bumps and pustules. Facial redness may also improve with regular use. The gel fits easily into a daily routine and can be used with sunscreen and gentle skincare.
Topical metronidazole has low systemic absorption. This supports a favorable safety profile for long-term use under medical care. The 1% gel offers once-daily convenience, while the 0.75% gel can be used twice daily if preferred.
Ordering from YouDrugstore lets you access Canadian pharmacy pricing. Many patients save 60–80% compared to typical US prices. You can choose multi-month supplies to lower the per-month cost and reduce the need to reorder often.
Our team can answer order and shipping questions by chat during posted hours. If you have medication questions, our licensed pharmacists can help by phone as appropriate.
Side Effects and Safety
Most people tolerate Metrogel® well. Side effects can occur, especially when starting therapy. Seek medical care for severe or persistent reactions.
- Common: mild burning, stinging, dryness, redness, itching, or irritation at the application site.
- Less common: skin tightness, scaling, tingling, watery eyes, metallic taste (usually brief if product contacts lips).
- Rare but serious: severe skin irritation, contact dermatitis, swelling of the face or throat, hives, or difficulty breathing (possible allergy).
Use sunscreen and protective clothing, as sun exposure can worsen rosacea. Avoid harsh scrubs, astringents, and alcohol-based toners that may irritate skin. Tell your prescriber about other topicals you use to reduce additive irritation. Discuss use in pregnancy or while nursing with your clinician.
Onset Time
Some people notice calmer skin within 2–4 weeks. Bumps and redness continue to improve with steady use. The full effect may take 8–12 weeks. Keep using as directed unless your prescriber advises a change.
Compare With Alternatives
Azelaic acid is another first-line option for papules and pustules. It targets inflammation and keratin buildup. If you prefer azelaic acid, consider Finacea® as a prescription alternative often used for rosacea.
Ivermectin 1% cream is also used for inflammatory rosacea. It may be chosen when Demodex mites are suspected contributors. Some patients rotate therapies seasonally or based on tolerance. Your prescriber can choose the best fit.
For acne rather than rosacea, retinoids and other agents are common. A topical option is Retin A® Micro Gel Pump. For severe, nodular acne under specialist care, oral isotretinoin such as Clarus® may be used.
Combination Therapy
Metrogel® can be part of a broader plan. Many patients use a gentle cleanser, non-comedogenic moisturizer, and daily SPF 30+ sunscreen. For moderate to severe disease, clinicians may add oral therapies such as doxycycline. For persistent redness, a vasoconstrictor gel like brimonidine may be used separately.
Introduce new products one at a time. This helps identify triggers and limits irritation. Discuss any peels or in-office procedures with your provider while on topical therapy.
Patient Suitability and Cost-Saving Tips
Metrogel® suits many adults with inflammatory rosacea. It can also help in perioral dermatitis under clinician supervision. It is not designed for open wounds. It is not the same product as the vaginal metronidazole gel for bacterial vaginosis.
Save on costs by choosing generic metronidazole gel where appropriate. Compare sizes and strengths to match your prescription. You can receive reorder reminders so you do not run out. Multi-month supplies often reduce the monthly price.
For current deals and bulk options, visit our promotions page: metrogel coupon.
If rosacea is your main concern, explore our Rosacea and Facial Redness categories for other therapies. For acne-focused care, you can read our article Clarus Acne Treatment Your Solution For Clearer Skin. If you have questions about medication use in pregnancy, this overview may help your discussion with a clinician: Back Pain In Pregnancy Meds For Pregnant Women.
Authoritative Sources
- FDA DailyMed: Metronidazole topical gel labeling and patient information
- Health Canada Drug Product Database: Metronidazole topical listings
Order from YouDrugstore with confidence. We meet Canadian pharmacy standards, and a licensed pharmacist reviews each prescription before we ship. You can place your order online, and our team supports you through the process. We offer prompt, express, cold-chain shipping to the US when needed.
This information does not replace advice from your own clinician. Always follow your prescriber’s instructions and the patient leaflet that comes with the medication. Report unexpected side effects or severe reactions to a healthcare professional.
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What is Metrogel used for?
Metrogel is a topical form of metronidazole used mainly to treat inflammatory lesions of rosacea, including papules and pustules. It may also be used for perioral dermatitis when prescribed. It is for external skin use only and should not be confused with the vaginal metronidazole gel for bacterial vaginosis.
How do I apply the 0.75% vs 1% gel?
The 0.75% gel is typically applied twice daily in a thin layer to affected areas. The 1% gel is usually applied once daily. Cleanse and dry skin first, then apply a pea-sized amount per region as directed. Allow it to dry before sunscreen or makeup. Follow your prescriber’s instructions.
How long does Metrogel take to work?
Some improvement may be seen within 2 to 4 weeks as inflammation decreases. Bumps and facial redness often continue to improve with steady use. The full effect may take 8 to 12 weeks. Keep consistent unless your prescriber advises changes based on your skin’s response.
What side effects can occur with Metrogel?
Common effects include mild burning, stinging, dryness, redness, or itching at the application site. Less common effects include skin tightness, watery eyes, or a brief metallic taste if it contacts the lips. Stop and seek care for severe irritation, hives, swelling, or signs of an allergic reaction.
Can I use Metrogel with other skincare or makeup?
Yes, many people use gentle cleansers, non‑comedogenic moisturizers, and sunscreen with Metrogel. Apply the gel first to clean, dry skin and let it dry. Then apply moisturizer, sunscreen, and cosmetics. Avoid harsh scrubs, astringents, or alcohol‑based toners that may worsen irritation and redness.
Is Metrogel safe during pregnancy or while nursing?
Topical metronidazole has low systemic absorption and is often considered when benefits outweigh risks. Decisions during pregnancy or nursing should be made with your own clinician. Share all products you use, including over‑the‑counter items, to help guide safe choices for your situation.
What is the difference between Metrogel and the BV vaginal gel?
Metrogel for rosacea is a skin gel used on the face. The metronidazole vaginal gel for bacterial vaginosis is a different formulation with different instructions, dose, and applicators. Do not interchange them. Use only the product and route that match your prescription and condition.