Metrogel® for Rosacea Relief and Skin Redness Control

What Metrogel® Is and How It Works

Metrogel® is a brand of metronidazole topical gel used to reduce inflammatory lesions and facial redness linked to rosacea. It is available as 0.75% gel, usually applied twice daily, and as 1% gel, often applied once daily. A metronidazole vaginal gel 0.75% is also prescribed for bacterial vaginosis. A valid metrogel prescription is required; the generic for metrogel is metronidazole gel. Many shoppers compare metrogel cost without insurance when planning their treatment.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba; prescriptions are reviewed by licensed pharmacists before dispensing.

Topical metronidazole helps calm inflammation in rosacea and may reduce oxidative stress in the skin. It lowers the number of papules and pustules and can improve background facial redness over time. For bacterial vaginosis, intravaginal metronidazole decreases anaerobic bacterial overgrowth, helping restore a healthy vaginal microbiome. We also partner with licensed, vetted international pharmacies to source authentic brands and a wide range of generics at affordable prices.

Metrogel is used on the face and other affected areas as directed. Do not apply into the eyes, mouth, or inside the nose. The vaginal gel is applied intravaginally with a single-use applicator, typically at bedtime for several days, as prescribed.

Dosage and Usage

• Rosacea, metronidazole 0.75% gel: apply a thin layer to affected areas twice daily on clean, dry skin.
• Rosacea, metronidazole 1% gel: apply a thin layer once daily, usually in the evening.
• Wait until the gel dries before applying moisturizer, sunscreen, or cosmetics.
• Avoid eyes, lips, and broken skin; rinse with water if accidental contact occurs.
• Wash hands after application; do not share the tube or pump.
• Vaginal metronidazole 0.75% (for BV): insert one full applicator intravaginally at bedtime as prescribed, typically for 5 days.
• Missed dose (topical): apply when remembered unless close to the next scheduled time. Do not double-apply.
• Missed dose (vaginal): use as soon as remembered the same night if possible; resume the next night if it is already daytime.

• Store at 15–30 °C (59–86 °F) away from heat and direct light.
• Keep the cap tightly closed; do not freeze. Do not use if the seal is broken.
• Travel: keep the tube in a zip bag in your carry-on; gels count toward liquid allowances.
• Do not leave the product in a hot car. Keep out of reach of children and pets.
• Check the expiration date before use, and discard expired product.

Benefits and Savings

Metrogel can reduce inflammatory bumps and help even facial tone. It is fragrance-free and generally well tolerated for daily facial care. Once- or twice-daily dosing supports routine use with gentle cleansers and sunscreen. Many people choose metrogel for face care long term to maintain rosacea control.

Ordering from Canada often means 60–80% savings compared with typical US prices. You can compare metrogel price and metrogel cost across strengths. Savings may be significant for those paying without insurance. Multi-month supplies and bulk promotions can lower per-month costs, and you can turn on reorder reminders in your account to avoid gaps.

If you are looking for a metrogel coupon, check our current offers.

Side Effects and Safety

• Application-site burning, stinging, itching, or mild redness
• Dryness, flaking, or skin irritation
• Headache or metallic taste (uncommon)
• Nausea or stomach upset (uncommon with topical use)
• Vaginal discomfort or yeast overgrowth with the vaginal gel

Serious reactions are rare. Stop use and seek care for signs of allergy (hives, swelling, trouble breathing), severe skin irritation, numbness/tingling, or persistent headaches. Systemic absorption with topical gel is low, but avoid alcohol during therapy with vaginal metronidazole and for at least one day after the last dose. Ask your prescriber about use in pregnancy or while breastfeeding.

Onset Time

With rosacea, early improvement in inflammatory lesions may appear within 2–4 weeks. Redness and texture can continue to improve through 8–12 weeks as the dose schedule stabilizes. Use as directed for the full course before judging response. For bacterial vaginosis, symptom relief with bacterial vaginosis metrogel is often noticed within a few days, with most benefit by the end of the prescribed course.

Compare With Alternatives

Azelaic acid 15% gel is a common alternative for rosacea. It targets inflammatory lesions and background redness and can be used with metronidazole on alternating schedules based on tolerance. You can review Finacea® for details on brand azelaic acid.

Ivermectin 1% cream is another option for inflammatory papules and pustules of rosacea. It offers once-daily dosing and can be suitable if irritation occurs with other agents. Brimonidine gel or oxymetazoline cream may help transient facial erythema.

For BV, oral metronidazole tablets or clindamycin vaginal cream are alternatives if intravaginal gel is not suitable. Talk with your prescriber about the best metrogel substitute for your situation.

To learn more about azelaic acid, see our article Finacea Azelaic Acid Uses Benefits And How It Works, and explore the Rosacea and Facial Redness pages for condition-focused options.

Combination Therapy

• Pair with a gentle, fragrance-free cleanser and non-comedogenic moisturizer.
• Use broad-spectrum SPF 30+ daily to help limit flare triggers.
• Consider oral doxycycline for moderate to severe inflammatory rosacea per prescriber guidance.
• Alternate with azelaic acid if daily dual use causes irritation.
• Avoid harsh scrubs, alcohol-based toners, and known personal rosacea triggers.
• Do not drink alcohol during therapy with vaginal metronidazole and for at least one day after.

Patient Suitability and Cost-Saving Tips

Metrogel is intended for adults with inflammatory lesions of rosacea. Those allergic to metronidazole or other nitroimidazoles should not use it. Caution is advised in pregnancy or while breastfeeding; discuss risks and benefits with a healthcare professional. Children typically are not candidates for rosacea indications.

The vaginal formulation treats bacterial vaginosis in non-pregnant and pregnant adults when prescribed. People with a history of severe reactions to metronidazole should avoid it. Alcohol should be avoided during vaginal therapy and shortly after the course is finished.

Metrogel is not an over-the-counter product; questions about metrogel rosacea over the counter come up often, but a prescription is required. Both strengths are available; metrogel 0.75 for rosacea is commonly started, while metrogel 1 may suit once-daily routines. If budget is a concern, consider the generic for metrogel. When available, choosing a 90-day supply can reduce the metrogel 0.75 gel price or metrogel 1 price. You can set a reorder reminder in your account, and you may save on shipping by combining items. A note on metrogel vaginal price: it varies by brand vs generic and pack size.

Authoritative Sources

Metrogel (metronidazole) 1% topical gel Prescribing Information (FDA)

MetroGel (metronidazole) 0.75% Topical Product Monograph (Health Canada)

MetroGel-Vaginal (metronidazole) 0.75% Gel Prescribing Information (FDA)

Order Metrogel® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always speak with your healthcare provider about your specific needs.