Sildenafil Tablets for Erectile Dysfunction and Pulmonary Hypertension

What Sildenafil Is and How It Works

Sildenafil is a prescription phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction (ED) and for pulmonary arterial hypertension (PAH). It comes as film‑coated tablets, commonly 25 mg, 50 mg, and 100 mg strengths. Many adults use sildenafil 100mg for ED when lower doses are not enough.

Youdrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and pharmacists review prescriptions before dispensing. We offer brand and generic medicines at Canadian prices and also carry OTC health products.

We source through licensed, vetted international partner pharmacies to provide authentic brands, broad selection, and affordable pricing.

For ED, sildenafil supports erections by enhancing the natural nitric oxide–cGMP pathway. Sexual stimulation is still required. PDE5 inhibition increases blood flow to the corpus cavernosum, improving erection firmness and duration. For PAH (marketed as Revatio in some regions), sildenafil relaxes pulmonary blood vessels to reduce pressure and improve exercise capacity.

People often ask, sildenafil what does it do; it relaxes specific blood vessels and helps the body use its own signals more effectively. Many shoppers use terms like sildenafil generic viagra when comparing strengths and prices. This medication requires a valid sildenafil prescription.

Dosage and Usage

• ED usual starting dose: 50 mg taken about 30–60 minutes before sexual activity. Some patients may respond in 15–30 minutes; others need more time.
• ED dose range: 25 mg to 100 mg, as prescribed. Do not take more than once daily.
• Take with or without food. A high‑fat meal can slow onset and reduce peak effect.
• Avoid grapefruit while on sildenafil; it can increase blood levels.
• Alcohol may reduce response and increase side effects like dizziness.
• For PAH, typical dosing differs: 20 mg three times daily, spaced about 4–6 hours apart, as directed by the prescriber.
• Missed dose (ED as needed): not applicable; do not double doses.
• Missed dose (PAH): if a dose is missed, take the next dose at the regular time; do not double up.

• Storage: store tablets at 15–30 °C (59–86 °F) in a dry place away from moisture and light.
• Keep in the original container or blister until use to protect from humidity.
• Do not use tablets past the printed expiration date.
• For travel, keep sildenafil tablets in carry‑on baggage with the prescription label.
• Do not leave medicine in a hot car; avoid temperature extremes.
• Keep out of reach of children and pets.

Benefits and Savings

For ED, sildenafil can improve the ability to get and keep an erection long enough for satisfying intercourse. It does not increase sexual desire, and it works only with sexual stimulation. For PAH, sildenafil may reduce symptoms like shortness of breath and improve walking distance over time.

Ordering from Youdrugstore helps many patients save 60–80% compared with typical US prices. If cost matters, compare sildenafil price by strength. Some choose 50 mg or 25 mg based on tolerability and response, while others require 100 mg. The sildenafil 100mg price varies by pack size and manufacturer.

Many compare options at local pharmacies. People often check sildenafil at Walgreens or sildenafil Walmart and then review Canadian pricing. Buying from a licensed Canadian pharmacy can lower the per‑month sildenafil cost. Multi‑month supplies and bulk packs, when available, can reduce the average price per tablet.

You can buy sildenafil or place an order for sildenafil online after your prescriber issues a valid script. Your account can send gentle reorder reminders so you do not run out. This is helpful for those using sildenafil tablets regularly or for PAH dosing schedules.

Side Effects and Safety

• Common: headache, flushing, nasal congestion, indigestion, dizziness.
• Occasional: back pain, muscle aches, nausea, dry mouth, facial warmth.
• Vision changes: blue‑tinted vision, light sensitivity, or blurred vision.
• Cardiac‑related symptoms: palpitations or mild drop in blood pressure.
• Skin: rash or flushing episodes.
• Rare: prolonged erection (priapism), sudden hearing decrease, severe hypotension.

Serious but rare risks include priapism (erection lasting over four hours), non‑arteritic anterior ischemic optic neuropathy (NAION), severe hypotension, and sudden hearing loss. Never use nitrates (e.g., nitroglycerin) or riociguat with sildenafil due to dangerous blood pressure drops. Use caution with alpha‑blockers; spacing doses and starting low can reduce dizziness.

Onset Time

For ED, many notice effects within 30–60 minutes after a dose, with some benefit as early as 15–30 minutes. Peak response often occurs around 60 minutes, and the effect can persist for about four hours. A high‑fat meal may delay onset and lower peak levels.

For PAH, symptomatic improvement builds gradually. Some report better exercise tolerance within weeks, with continued gains over 8–12 weeks as therapy continues and the dose is maintained.

Compare With Alternatives

Tadalafil offers a longer half‑life and a flexible dosing approach. It can be taken as needed or once daily for continuous coverage. Some prefer the longer window for spontaneity, while others prefer shorter action. Consider Tadalafil if a longer duration fits lifestyle and response.

Sildenafil is the generic of Viagra. Some people remain on the brand for specific reasons. If brand is preferred, see Viagra®. Avanafil and vardenafil are other PDE5 inhibitors; avanafil may have a quicker onset for some users. Choice depends on response, onset, duration needs, and side‑effect profile.

Combination Therapy

• Testosterone therapy: considered when documented hypogonadism contributes to ED.
• Psychosexual counseling: useful when performance anxiety or relationship issues are present.
• Vacuum erection devices: can be combined with PDE5 inhibitors for added rigidity.
• Alpha‑blockers: if needed for BPH, use the lowest effective sildenafil dose and separate dosing to reduce hypotension risk.
• Antihypertensives: monitor blood pressure; avoid abrupt dose changes without prescriber guidance.
• Nitrates or riociguat: do not combine due to severe blood pressure lowering.

Patient Suitability and Cost-Saving Tips

Sildenafil may suit adults with ED who are medically stable for sexual activity. It may not be appropriate for those using nitrates, riociguat, or with severe hypotension. Caution is needed after recent heart attack or stroke, with unstable angina, severe liver disease, or certain eye conditions.

For PAH, sildenafil helps reduce pulmonary pressure and improve exercise tolerance. Because it can lower systemic blood pressure, clinicians often review antihypertensive regimens. Queries like sildenafil for blood pressure reflect this effect; it is not a standard treatment for general hypertension.

Sildenafil is not approved for premature ejaculation. Some men report better control due to improved erection quality, but it is not a specific treatment for timing. Discuss concerns with a clinician to confirm the condition and consider targeted therapies if needed.

To manage costs, compare sildenafil cost by strength and manufacturer. Check sildenafil 50 mg price in addition to higher doses. The price of sildenafil 100mg often drops with larger packs. Multi‑month orders can lower per‑month costs. Your account can send friendly reorder reminders to help maintain supply.

Shoppers sometimes use terms like order sildenafil, sildenafil online, or sildenafil for sale online. You can place a safe sildenafil online purchase with a valid prescription and have sildenafil pills shipped discreetly to your door.

Authoritative Sources

US FDA Prescribing Information for Sildenafil (tablets) – uses, dosing, and risks

Health Canada Drug Product Database entry for Sildenafil – Canadian details

Manufacturer information for Viagra (brand of sildenafil)

Order Sildenafil from Youdrugstore: add to cart, upload your prescription, and we ship with prompt, express shipping.

This page is educational and does not replace advice from a qualified healthcare professional. Always follow your prescriber’s directions and the patient leaflet in your package.