Sildenafil Tablets for Erectile Dysfunction and PAH

What Sildenafil Is and How It Works

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). For ED, common strengths include 25 mg, 50 mg, and sildenafil 100mg tablets taken as needed. For PAH, the 20 mg strength is used on a scheduled basis. Sildenafil citrate increases blood flow where it is needed by blocking PDE5 and enhancing nitric oxide effects.

YouDrugstore is a licensed Canadian pharmacy in Manitoba that follows Canadian pharmacy standards. Prescriptions are reviewed by licensed pharmacists before dispensing. You can order sildenafil online or by phone during posted hours, and our friendly customer-service chat can help with ordering questions.

We work with licensed, vetted partner pharmacies internationally to supply authentic brand medications and a broad range of generics at affordable pricing. This helps keep your sildenafil cost lower while offering a reliable selection.

Sildenafil tablets improve erectile response during sexual stimulation. In PAH, sildenafil 20 mg helps relax blood vessels in the lungs to lower pulmonary pressures and support exercise capacity. The medication is available as generic sildenafil, and brand versions also exist.

Dosage and Usage

ED dosing usually starts at 50 mg taken about one hour before sexual activity. The dose may be adjusted to 25 mg or 100 mg based on response and tolerability. Do not take more than once per day. A high-fat meal may delay onset.

For PAH, the typical adult regimen is 20 mg three times daily, spaced 4 to 6 hours apart. Do not change the dose without your prescriber’s guidance.

• Take with a glass of water; tablets can be taken with or without food.
• Avoid grapefruit and grapefruit juice due to interaction risk.
• Alcohol may reduce erectile function and increase dizziness.
• Missed dose (PAH): take when remembered unless close to the next dose; do not double.
• ED use is on an as-needed basis, so a missed dose does not apply.

Storage and travel:

• Store your sildenafil tablets at room temperature, 15–30°C (59–86°F), away from moisture.
• Keep tablets in the original container with the label in your carry-on when you travel.
• Use a pill organizer for short trips; bring enough supply for your full stay.
• Keep out of reach of children and pets.

Benefits and Savings

Sildenafil tablets are well studied for ED and have helped many men achieve and maintain erections for sexual activity. For PAH, sildenafil 20 mg can support exercise ability and quality of life when used as directed by a specialist. Many patients prefer generic sildenafil because it offers the same active ingredient as the brand at lower cost.

Ordering through YouDrugstore offers convenience and value. You can buy sildenafil, compare strengths like sildenafil 25 mg, sildenafil 50 mg, and 100mg sildenafil tablets, and ship to the US at Canadian prices. Typical savings are 60–80% versus common US pricing.

Side Effects and Safety

Most side effects are mild and short-lived. Some require prompt medical care. Review risks and interactions with your healthcare provider before starting a sildenafil prescription, especially if you have heart or eye conditions.

• Common: headache, flushing, nasal congestion, indigestion, dizziness, back pain.
• Less common: visual color tinge (blue/green), blurred vision, light sensitivity, rash.
• Serious: sudden vision loss (possible NAION), sudden hearing decrease or loss, chest pain, fainting, severe dizziness, allergic reaction (swelling, trouble breathing), priapism (erection lasting more than 4 hours).
• Contraindicated: nitrates (e.g., nitroglycerin, isosorbide), riociguat.
• Use caution with alpha-blockers, significant cardiovascular disease, recent stroke or heart attack, severe hepatic impairment, severe renal impairment, or retinitis pigmentosa.
• Drug interactions: strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) can increase levels; dose adjustments or alternative therapy may be needed.

Onset Time

Onset is typically 30–60 minutes for ED. A high-fat meal may delay effect by up to two hours. Duration often lasts about four hours, with variability by dose and individual response. For PAH, benefits are tied to regular dosing over time rather than a single dose effect.

Compare With Alternatives

Brand Viagra® contains the same active ingredient as generic sildenafil and offers branded packaging and support materials. The clinical effect is comparable when the same dose is used. Many choose generic sildenafil tablets for cost savings while maintaining efficacy.

Tadalafil is another PDE5 inhibitor. It can be taken as needed or once daily. Its longer half-life allows a 24–36 hour window of responsiveness, which some find more flexible. On the other hand, tadalafil may interact differently and has its own side effect profile.

Vardenafil and avanafil are additional ED options. They have similar mechanisms with differences in onset, duration, and interaction potential. A prescriber’s guidance helps match therapy to medical history, other medications, and personal preference.

Combination Therapy

Do not combine sildenafil with other PDE5 inhibitors or with any nitrate therapy. This can cause dangerous drops in blood pressure. Sildenafil may be considered with testosterone replacement in confirmed hypogonadism under medical supervision.

For PAH, specialists sometimes combine sildenafil 20 mg with other PAH agents such as endothelin receptor antagonists or prostacyclin pathway drugs. Specialist follow-up is essential for monitoring and dose adjustments.

Patient Suitability and Cost-Saving Tips

Sildenafil medication may suit adults with ED without contraindicated conditions or interacting drugs. A lower starting dose is common for older adults, those on potent CYP3A4 inhibitors, or when side effects occur. For PAH, specialist assessment confirms the diagnosis and dosing plan.

You can buy sildenafil online through YouDrugstore and select the strength that fits your prescription. You can also order sildenafil for multi-month supplies when permitted. Larger quantities often lower the per-month price. We offer optional reorder reminders so that your supply does not run out.

Comparing strengths can help align effect and tolerability. Some need sildenafil 25 mg, while others use sildenafil 50 mg or sildenafil 100mg based on response. If cost is a concern, generic sildenafil often offers the best sildenafil price versus brand. You can review the sildenafil 100mg price and other strengths on the product page before checkout.

If you are exploring treatment options, our Erectile Dysfunction category offers related products and supports informed decisions. For PAH, see our Pulmonary Hypertension section to learn more about therapy approaches.

For more reading, see Everything You Need To Know About Sildenafil 100 Mg and Early Erectile Dysfunction Symptoms To Watch For. If comparing agents, you may find What Is Tadalafil The Ed Medication You Should Know About helpful.

Authoritative Sources

FDA Prescribing Information for Viagra (sildenafil)

FDA Prescribing Information for Revatio (sildenafil)

Health Canada Drug Product Database: Sildenafil

YouDrugstore offers brand and generic medicines at Canadian prices with secure checkout. Our team supports your order, and pharmacists can address medication questions. We provide prompt, express shipping to the US.

This content is for general information. It does not replace professional medical advice, diagnosis, or treatment. Always follow your prescriber’s directions and the product labeling.