Synthroid® (levothyroxine) Tablets for Hypothyroidism and TSH Suppression

What Synthroid® Is and How It Works

Synthroid® is a brand of levothyroxine sodium. It replaces or supplements thyroxine (T4) for underactive thyroid. Main uses include primary hypothyroidism, pituitary or hypothalamic disease, and TSH suppression after thyroid cancer. It also treats or prevents goiter in select cases. This synthroid medication is taken by mouth once daily. Many strengths exist, including 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg, and 300 mcg. You may see common sizes like synthroid 25 mcg, synthroid 50 mcg, synthroid 75 mcg, synthroid 100 mcg, and synthroid 150 mcg. People often compare synthroid cost without insurance when planning long-term therapy.

As a licensed Canadian pharmacy based in Manitoba, YouDrugstore meets Canadian pharmacy standards. A valid Synthroid prescription is required, and our licensed pharmacists review each order before dispensing. We offer brand and generic medicines at Canadian prices, and online ordering is available.

We work with licensed, carefully screened partner pharmacies abroad to source authentic brands with a wide selection at budget-friendly pricing.

Levothyroxine is a synthetic T4, which the body converts to T3 in tissues. Stable circulating T4 normalizes TSH, relieves hypothyroid symptoms, and supports normal metabolism. This medicine is not for weight loss, and higher doses for that purpose can be unsafe.

Dosage and Usage

Dosing is individualized. Your prescriber sets the starting dose and adjusts it using TSH and clinical response. Tablets are taken on an empty stomach, once daily.

• Take Synthroid® once daily with water, on an empty stomach.
• Wait 30 to 60 minutes before eating or drinking coffee.
• Start doses vary. Healthy adults often start near 1.6 mcg/kg/day. Older adults or those with heart disease may start at 12.5 to 25 mcg/day.
• Adjust by 12.5 to 25 mcg every 4 to 6 weeks based on TSH.
• Swallow tablets whole. If needed, certain strengths may be crushed and mixed with water, as directed.
• Separate calcium, iron, antacids, and bile-acid binders by at least 4 hours.
• If you miss a dose, take it when remembered the same day. Skip if near the next dose. Do not double.
• Pregnancy often increases levothyroxine needs. Doses are monitored during and after pregnancy.

• Store tablets at 20 to 25°C (68 to 77°F).
• Keep in the original container. Protect from moisture, heat, and light.
• Do not store in the bathroom. Keep away from children and pets.
• When you travel, keep medication in your carry-on.
• Bring a copy of your prescription and extra tablets for delays.
• Avoid extreme temperatures, including hot cars.

Benefits and Savings

Synthroid therapy restores normal thyroid hormone levels. Many patients experience improved energy, mood, cognition, and bowel regularity. It supports healthy heart rate, skin, and hair. Tablets come in small dose steps, which helps fine-tune TSH. Once-daily dosing aids adherence.

YouDrugstore offers brand and generic options at Canadian prices and US shipping. Expect typical 60 to 80 percent savings versus many US retail prices. This helps if you buy Synthroid without insurance. You can order synthroid online, and our customer-service chat is available during posted office hours for support.

We also support multi-month supplies when appropriate. A 90-day fill can lower the per-month synthroid price and reduce trips. Reorder reminders help you stay on track.

Side Effects and Safety

Most side effects reflect dose sensitivity or interactions. Report severe or persistent effects to your prescriber.

• Common: headache, nervousness, irritability, tremor, sweating, heat intolerance.
• Other: appetite change, weight change, diarrhea, vomiting, insomnia, palpitations.
• Hair loss may occur early in treatment and is usually temporary.
• Serious: chest pain, rapid or irregular heartbeat, shortness of breath, fainting.
• Bone thinning can occur with chronic over-replacement, especially postmenopausal.
• Allergic reactions to inactive ingredients are possible, though uncommon.

Key cautions include uncorrected adrenal insufficiency and untreated thyrotoxicosis. This drug is not indicated for obesity treatment. Some medicines reduce absorption or change levels. Separate calcium, iron, magnesium, aluminum antacids, cholestyramine, and colesevelam. Rifampin, carbamazepine, phenytoin, and sertraline may change dosing needs. Warfarin sensitivity can increase. Diabetes medications may need adjustment. Keep dosing consistent with meals and coffee for steady absorption.

Onset Time

Many people notice symptom changes within one to two weeks after starting or adjusting doses. TSH lags behind by several weeks. Clinicians usually check TSH 6 to 8 weeks after a dose change. Full stabilization may take a few months.

Compare With Alternatives

Generic levothyroxine tablets are the generic drug for Synthroid. They are considered therapeutically equivalent when used consistently. Inactive ingredients may differ, which can affect absorption in some patients. If switching products, prescribers often recheck TSH after 6 to 8 weeks.

Tirosint softgel or solution contains levothyroxine with fewer excipients. It may help in malabsorption, sensitivity to dyes, or when avoiding lactose or gluten. Cost may be higher compared with tablets.

Natural desiccated thyroid products contain T4 and T3 from porcine thyroid. Potency can vary by lot, and T3 content is fixed. Some patients prefer this option with careful monitoring. Learn more by reviewing Thyroid Tablets with your clinician.

Liothyronine (T3) may be used with levothyroxine in select cases. Monotherapy with T3 is not routine because of short half-life and peak effects.

Combination Therapy

Most patients do well on T4-only treatment. A subset may benefit from a T4/T3 combination under specialist guidance. Dosing is individualized, and careful monitoring is required to avoid hyperthyroid symptoms. For TSH suppression after thyroid cancer, higher levothyroxine doses may be used with specialist oversight.

For best absorption, separate levothyroxine from calcium, iron, and multivitamins by at least 4 hours. Keep dosing time consistent. If taking bile-acid resins, timing and monitoring are needed.

Patient Suitability and Cost-Saving Tips

Synthroid treatment fits most patients with primary or central hypothyroidism, post-thyroidectomy replacement, and TSH suppression after certain thyroid cancers. Caution is needed in coronary artery disease, arrhythmias, and elderly patients. It is contraindicated in uncorrected adrenal insufficiency and untreated hyperthyroidism.

To lower your synthroid cost, consider a 90-day supply when appropriate. Multi-month fills often reduce the per-month synthroid cost. You can set simple reorder reminders to prevent gaps. A consistent manufacturer can avoid TSH swings. Discuss the generic drug for synthroid if you want to reduce your synthroid price. If you compare synthroid cost no insurance, Canadian pricing may help your budget.

For offers and bulk options, see our synthroid coupon page for current promotions.

Explore condition guides like Hypothyroidism and Thyroid Cancer to learn more about ongoing care. You can also review articles such as What Is Synthroid A Simple Guide To Its Uses Benefits and Thyroid Drugs for simple education on dosing and monitoring.

Authoritative Sources

See the manufacturer’s patient information on the Synthroid website. The Health Canada listing provides official Canadian product details in the Drug Product Database entry for Synthroid (levothyroxine). US labeling is available in the FDA Prescribing Information.

Order from YouDrugstore with confidence. Our team supports you from checkout to delivery, and pharmacists can address medication questions. We offer prompt, express shipping to the US through a reliable synthroid delivery program.

This content is for general information. It does not replace advice from your own healthcare professional. Always follow your prescriber’s directions and the package information that comes with your medicine.