Shipping with this method takes 3-5 days
Ubrelvy® Tablets for Acute Migraine
Stock up and Save - Get 20% off when you buy 3 or more of any one product. Use code SAVE20 at checkout.
Coupon code cannot be combined with other offers. Sale applies to all products originating from Canada. Maximum allowable quantity equal to a 90 day supply per single order.
$198.99
Secure Encrypted Payments
Ubrelvy® is a prescription medicine for acute migraine attacks in adults. This page explains how it works, who it may suit, and how to use it safely, with US delivery from Canada and options if you pay without insurance.
What Ubrelvy Is and How It Works
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This medicine contains ubrogepant, a CGRP receptor antagonist. It helps reduce migraine pain and bothersome symptoms by blocking CGRP activity during an attack. It is taken only when a migraine starts, not for prevention. It is not an opioid and not a triptan. For some people who cannot use triptans, it may be a suitable option after your prescriber reviews your history.
Ubrogepant tablets work on migraine pathways without causing vasoconstriction. Many adults prefer an oral option they can carry for use at the first sign of an attack. Learn about migraine basics in our overview of Migraine and see other neurologic treatments under Neurology.
Who It’s For
This treatment is for adults with migraine, with or without aura. It is meant for acute use at the onset of an attack. It is not a preventive therapy. People with severe liver problems or on certain interacting medicines may need a different option. Your prescriber will decide if this therapy is appropriate for you, considering other conditions and your current medication list.
If you want background reading on attacks and symptoms, explore Migraine Headaches and advocacy insights from Migraine Awareness.
Dosage and Usage
Use this medicine when a migraine begins or when symptoms start to build. Swallow the tablet with water. You can take it with or without food. If your headache returns or does not resolve, a second dose may be taken at least two hours after the first, if directed by your prescriber. Do not exceed the maximum daily amount on the official label. The safety of treating more than eight migraine days per month has not been established.
Your prescriber may provide specific guidance if you take certain other medicines. Ask if an anti-nausea option such as Metoclopramide is right for you when nausea is prominent. For dosing questions, refer to the official label rather than adjusting on your own. This section includes the exact phrase: Ubrogepant dosage.
Strengths and Forms
Available as film-coated tablets in two strengths commonly published for this product: 50 mg and 100 mg. Packaging and imprint may vary by lot. This page focuses on oral tablets; other forms are not offered for this therapy.
Missed Dose and Timing
This medicine is used as needed. If you did not take it at the onset, you may still take it later during the same attack as directed. If the headache has resolved, do not take an extra dose. If you vomit soon after taking a tablet, contact your prescriber for advice rather than re-dosing without guidance.
Storage and Travel Basics
Store tablets at room temperature in the original container with the lid tightly closed. Keep them dry and away from excessive heat or direct light. Do not store in a bathroom or glove compartment. Keep out of reach of children and pets.
When traveling, keep your medication in your carry-on, along with a copy of your prescription. A simple medication list can help during security or if you need care while away. Use a daily reminder so you have it available when an attack starts.
Benefits
This class targets a migraine pathway involved in pain transmission. Oral dosing is convenient for people who prefer a tablet over an injectable or nasal option. It can be taken with or without food, which may be helpful when nausea is mild. Because it is not a triptan, it may be considered when vasoconstrictive options are unsuitable, as determined by your prescriber.
Side Effects and Safety
- Nausea: usually mild and transient
- Sleepiness or fatigue: use caution with tasks that need alertness
- Dry mouth: sip water or use oral moisturizers
Serious reactions are uncommon but can include hypersensitivity. Stop the medicine and seek medical care if you develop swelling, wheezing, or hives. People with significant liver impairment require careful review. Always tell your prescriber about all medicines and supplements you use.
Drug Interactions and Cautions
Strong CYP3A4 inhibitors (for example, certain antifungals or macrolide antibiotics) can increase levels and are generally avoided. Strong inducers (such as rifampin) may reduce effectiveness. Grapefruit and some herbal products can interact by affecting metabolism. Your prescriber may modify the plan if you use moderate inhibitors or P-gp/BCRP inhibitors. Using preventive options such as Qulipta® or beta-blockers like Ketorolac is handled separately; do not change doses without guidance. Always review the full interaction list on the official label.
What to Expect Over Time
Some people notice easing of pain and sensitivity during the same day they treat an attack. Others may need a second dose per label directions. Individual response can vary from one attack to the next. If attacks remain frequent, your clinician may discuss preventive strategies so you rely less on acute therapy. Keep a simple headache diary to track triggers, response, and usage.
Compare With Alternatives
Common acute options include triptans and certain NSAIDs. A classic option is Sumatriptan, which acts on serotonin receptors. An NSAID solution, Cambia® (diclofenac potassium), can also help pain and sensitivity. Another triptan, zolmitriptan, is available in several forms. Your prescriber can help you choose based on health history, side effects, and prior response.
Pricing and Access
See Ubrogepant price by selecting your strength and quantity. Transparent pricing lets you compare options for your prescription. If you are looking for added savings, check for an Ubrelvy coupon when available. We offer Canadian pricing with fair access for US patients.
Ordering is straightforward, and we provide secure payment with encrypted checkout. This product Ships from Canada to US after a valid prescription is received. For site-wide deals, visit our Promotions page.
Availability and Substitutions
Stock may vary based on supply. If this item is unavailable, your prescriber may suggest an alternative in the same class or a triptan. We also fill preventive therapies when appropriate. If you prefer brand sourcing, ask about Ubrelvy from Canada during checkout notes so our team can assist.
Patient Suitability and Cost-Saving Tips
This therapy suits adults diagnosed with migraine who need an on-demand option. It is not indicated for prevention or for cluster headache. People with severe liver disease, on certain interacting medicines, or who are pregnant or breastfeeding should discuss risks and options with their prescriber.
Cost tips: consider a multi-month supply if your usage is predictable, set refill reminders in your account, and review your plan annually with your prescriber. If you compare options, check Ubrelvy price per pill against other acute therapies to align with your budget. Category browsing under Migraine can help you find alternatives and supportive care.
Questions to Ask Your Clinician
- When should I take the first dose during an attack?
- Can I take a second dose, and how long should I wait?
- Which medicines or supplements should I avoid with this treatment?
- What signs mean I should seek urgent care after dosing?
- How many migraine days per month should I aim to treat?
- Would a preventive option reduce my attack frequency?
- How should I manage nausea when it is severe?
Authoritative Sources
Ubrelvy Prescribing Information (AbbVie)
Health Canada Drug Product Database
Ready to proceed? Place your order with express US shipping from Canada. All orders are handled with care and temperature-controlled handling when required. This content is for general information and does not replace your prescriber’s advice; always follow the official label.
Express Shipping - from $25.00
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
How does ubrogepant differ from triptans for migraine?
Ubrogepant blocks calcitonin gene-related peptide (CGRP) receptors, a pathway involved in migraine pain. Triptans act on serotonin receptors and can cause vasoconstriction. Because the mechanisms differ, your prescriber may suggest ubrogepant when triptans are not suitable or have not worked well. Both are for acute use, not prevention. Your medical history, other medicines, and prior response help determine the best option for you.
Can I take this medicine with food or caffeine?
You can take the tablet with or without food. Some people prefer a light snack if nausea is present. Caffeine appears in many over-the-counter migraine products; using modest amounts is common, but excess caffeine may worsen headache patterns. If you regularly use caffeine or analgesics, discuss potential medication overuse with your prescriber and follow the official label for safe limits.
What if my symptoms return after the first dose?
If your symptoms return, a second dose may be taken at least two hours after the first, provided your prescriber has advised that approach. Do not exceed the maximum daily amount on the label. If you need second doses frequently or still have significant impairment, check in with your clinician. They may adjust your plan or discuss prevention to reduce monthly attack days.
Is it safe with antidepressants or anti-anxiety medicines?
There is no known serotonin-mediated interaction like that seen with triptans and certain antidepressants. However, ubrogepant is metabolized by CYP3A4, and some psychiatric medicines or adjuncts may affect levels. Always provide a full medication list, including supplements and herbs, so your prescriber can screen for interactions and decide on dose adjustments if needed.
Can I drive after taking a dose?
Drowsiness and fatigue can occur. See how you respond before driving or operating machinery. Avoid alcohol or other sedating products when you first try this medicine. If you feel sleepy, arrange alternative transport and rest until the effect passes. Report persistent sedation to your prescriber, as a different approach or supportive medication may be considered.
What if I am pregnant or breastfeeding?
Human data are limited. Your prescriber will weigh potential benefits and risks before recommending therapy during pregnancy or while breastfeeding. If you are planning to become pregnant, discuss options early so you have a plan for acute attacks. Do not start or stop prescription medicines in pregnancy without medical guidance. Review the product label for the most current information.
Does it prevent future migraines?
No. Ubrogepant is for treating an active attack. If you have frequent migraine days, your prescriber may discuss preventive choices to reduce monthly frequency. Options can include CGRP preventives, beta-blockers, or other therapies based on your history. Keep a simple headache diary so you can review patterns and response during follow-up visits.
