Perindopril® Oral Tablets for Hypertension and Heart Protection

What Perindopril® Is and How It Works

Perindopril is an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension and lower cardiovascular risk in stable coronary artery disease. This perindopril medication helps relax blood vessels, reduce resistance, and improve blood flow. Many people know it as a high blood pressure medication perindopril, taken once daily as tablets.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba; pharmacists review prescriptions before dispensing, and we offer brand and generic medicines at Canadian prices along with OTC health products, with online ordering and customer-service chat during posted office hours.

If you are comparing perindopril 4mg price across pharmacies, you can review perindopril cost and perindopril price options before you order. We work with licensed, vetted international partner pharmacies to supply authentic brands and a wide selection of generics at affordable pricing.

Perindopril lowers angiotensin II production and reduces aldosterone. This widens arteries and decreases blood pressure, which can protect the heart, brain, and kidneys over time. It is approved for adults with hypertension and for reducing the risk of heart events in stable coronary artery disease.

Strengths vary by salt form and market. Common tablets include perindopril 4mg and perindopril 8mg (often perindopril erbumine). Some regions offer perindopril 5mg and perindopril 10mg (often arginine or perindopril tosilat). Recognized manufacturers and labels include perindopril Teva, perindopril Sandoz, and perindopril Servier. In some markets, fixed combinations pair perindopril and indapamide for added blood pressure control.

Dosage and Usage

• Typical hypertension initiation: 4 mg once daily. Titrate based on response and clinical guidance, often to 8 mg daily. Some patients may start lower when on diuretics.
• Stable coronary artery disease: often 4 mg once daily for two weeks, then 8 mg once daily if tolerated.
• Arginine salt labeling may show perindopril 5mg and perindopril 10mg, which correspond to similar target doses in some markets.
• Take at the same time each day, with or without food. Swallow tablets whole with water.
• If you miss a dose, take it when remembered unless it is close to the next dose. Do not double up.
• Monitor blood pressure regularly. Prescribers may check kidney function and potassium.
• Avoid potassium supplements or salt substitutes unless your prescriber advises them.
• Do not stop this therapy without consulting your prescriber, especially if used for heart protection.

• Store tablets at 15–30°C (59–86°F) in a dry place, away from light.
• Keep in the original bottle or blister to protect from moisture.
• Do not store in a bathroom. Keep out of reach of children and pets.
• For travel, carry your medicine in original labeled packaging in your carry-on.
• No refrigeration is required. Avoid extreme heat (hot cars, heaters).
• Crossing time zones: keep the once-daily interval consistent. Use reminders.
• Pack extra tablets and a copy of your prescription for longer trips.

Benefits and Savings

Perindopril lowers high blood pressure and helps reduce the risk of heart attack and stroke in appropriate patients. Once-daily dosing is convenient, and a wide range of strengths supports flexible titration. Many patients see steady blood pressure improvements and fewer pressure spikes during the day.

Ordering from Canada can offer meaningful savings. Compared with typical U.S. prices, you may save 60–80% when you buy perindopril online. Multi-month supplies often reduce the per-month cost, and you can set gentle reorder reminders so you do not run out. You can compare perindopril cost by strength and manufacturer.

Side Effects and Safety

• Cough (dry, persistent)
• Dizziness or lightheadedness, especially when starting or increasing the dose
• Headache or fatigue
• Nausea, diarrhea, or abdominal discomfort
• Low blood pressure, especially with dehydration or diuretics
• Increased potassium
• Rash or taste changes

Serious but less common risks include angioedema (swelling of the face, lips, tongue, or throat), severe low blood pressure, kidney problems, high potassium, and rare liver injury. ACE inhibitors carry a boxed warning for fetal toxicity; do not use in pregnancy. Avoid combining with aliskiren in diabetes. Use caution with NSAIDs, potassium-sparing diuretics, lithium, and dual renin-angiotensin system blockade.

Onset Time

Blood pressure can begin to decrease within hours of a dose, with meaningful improvement over several days. Many people see the full effect after one to two weeks at a stable dose. Some may require three to four weeks to reach the maximal response. Cardiovascular risk reduction builds with consistent, long-term use.

Compare With Alternatives

Lisinopril is another ACE inhibitor taken once daily. It offers similar efficacy for hypertension and cardiovascular protection, with a comparable side-effect profile including cough. Some patients switch based on response, tolerability, or availability.

Losartan is an angiotensin receptor blocker (ARB). It does not affect bradykinin and may be preferred if ACE-inhibitor cough occurs. ARBs provide comparable blood pressure control and organ protection in many settings.

Combination therapy options include indapamide perindopril for patients needing greater blood pressure reduction. A fixed-dose perindopril and indapamide tablet can simplify regimens. In some markets, teva perindopril indapamide products are available.

Combination Therapy

• Perindopril with a thiazide-like diuretic such as indapamide for additive blood pressure lowering.
• Perindopril with a calcium channel blocker (for example, amlodipine) when additional control is needed.
• Avoid combining ACE inhibitors with ARBs or aliskiren unless directed by a specialist.
• If already on a diuretic, prescribers may start a lower ACE inhibitor dose to reduce hypotension risk.

Patient Suitability and Cost-Saving Tips

Perindopril is intended for adults with hypertension or stable coronary artery disease risk reduction. It may be considered when an ACE inhibitor is appropriate and tolerated. It is not suitable for use during pregnancy or in anyone with a history of angioedema related to ACE inhibitors. Caution is advised with significant kidney disease, hyperkalemia, bilateral renal artery stenosis, dehydration, or severe aortic stenosis.

Different strengths and salt forms exist across markets. You may see labels for perindopril 4mg, perindopril 8mg, perindopril 5mg, or perindopril 10mg depending on the product. Reputable suppliers include perindopril Teva, perindopril Sandoz, and perindopril Servier. Some regions also offer perindopril tosilat formulations. If combination therapy is needed, ask about indapamide perindopril options.

To reduce costs, compare pack sizes and manufacturers. Multi-month supplies can lower the monthly price. Set reorder reminders so you stay on track. Generics often offer strong value compared with brands, while maintaining quality. You can review perindopril price differences by strength before placing your order.

Authoritative Sources

Manufacturer Coversyl product information (perindopril)

Health Canada Drug Product Database: perindopril (Coversyl)

European Medicines Agency: human medicines information (perindopril)

Order Perindopril® from YouDrugstore.com: add to cart, upload your prescription, and we ship with prompt, express shipping.

This content is educational and does not replace personalized medical advice from your healthcare professional.