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Adalat XL® Extended-Release Tablets for Hypertension and Angina
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Adalat XL is a prescription calcium channel blocker used for high blood pressure and chest pain. This page explains uses, dosing, safety, and access with US shipping from Canada. It also covers options if you pay without insurance.
What Adalat XL Is and How It Works
Adalat XL® is the brand name for nifedipine in a sustained-release tablet. Adalat XL extended-release tablets gradually release medicine over 24 hours to help control blood pressure and reduce angina episodes. The active ingredient is a dihydropyridine calcium channel blocker that relaxes vascular smooth muscle. This action lowers peripheral resistance and reduces the workload on the heart.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
The treatment is taken once daily to provide steady levels throughout the day. It may improve exercise tolerance in people with stable angina. Swallow the tablets whole to preserve the extended-release mechanism.
Learn more about related conditions and options: Hypertension, Angina, and our Cardiovascular category.
Who It’s For
This medicine is used in adults for the management of essential hypertension and for the prevention of chronic stable angina. Nifedipine ER may also be chosen when a once-daily calcium channel blocker is preferred. People with very low blood pressure, severe aortic stenosis, or a recent heart attack should discuss risks with a healthcare professional before starting. Your prescriber will consider your history, other medicines, and treatment goals.
Dosage and Usage
Follow your prescriber’s directions on dose and timing. Most adults take the extended-release tablet once daily, preferably at the same time each day. Swallow whole with water; do not cut, crush, or chew. You may take it with or without food, but keep the timing consistent day to day. Avoid grapefruit or grapefruit juice, which can raise nifedipine levels. If your clinician changes your dose, use the new regimen starting with the next scheduled dose. Always refer to the official product information if uncertain.
Administration tips:
- Consistent time: take in the morning or evening as directed.
- Whole tablet: do not alter the tablet; the shell may pass in stool.
- Monitor: track blood pressure at home and record readings.
- Alcohol: limit intake; it may increase dizziness or flushing.
Strengths and Forms
This therapy is supplied as extended-release oral tablets. Availability can vary by manufacturer and market. Common options include Adalat XL 30 mg; your prescription will specify which strength you need.
Missed Dose and Timing
If you miss a dose of nifedipine extended-release tablets, take it when you remember the same day. If it is close to the next scheduled time, skip the missed dose and resume your usual routine. Do not double up. Keeping a pill organizer or reminder on your phone can help you stay on track.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep them in the original container with the label intact. Protect from light and keep out of reach of children and pets. For travel, carry the medicine in your hand luggage with a copy of your prescription. Keep a list of your medicines and doses. If you cross time zones, stay as close as possible to your normal schedule and ask your prescriber if you need help adjusting times.
Benefits
This medicine provides 24-hour coverage with once-daily dosing. It can help reduce angina frequency and improve exercise capacity. Steady blood pressure control may support cardiovascular risk reduction as part of a comprehensive plan that can include diet, activity, and other therapies advised by your prescriber.
Side Effects and Safety
Common effects may include:
- Headache or flushing
- Dizziness or lightheadedness
- Peripheral edema (ankle swelling)
- Fatigue
- Nausea
- Heart pounding or palpitations
Serious effects are uncommon but can include severe hypotension, worsening chest pain on initiation or dose change, allergic reactions, or liver-related issues. Gum overgrowth can occur with long-term use. Seek medical attention for chest pain that is new, severe, or different from usual, or for symptoms of an allergic reaction such as rash, swelling, or trouble breathing. Use care when standing up quickly, as dizziness can occur, especially when starting therapy.
Drug Interactions and Cautions
Tell your prescriber and pharmacist about all medicines and supplements you use. Strong CYP3A inhibitors (for example, certain macrolide antibiotics, azole antifungals, protease inhibitors) can raise nifedipine levels. Inducers (such as rifampin or St. John’s wort) may reduce effectiveness; rifampin is generally contraindicated. Grapefruit juice can increase exposure and should be avoided. Combining with other blood pressure-lowering therapies may increase the risk of dizziness or fainting. Liver impairment may require closer monitoring.
What to Expect Over Time
Blood pressure typically improves with consistent daily use, along with lifestyle measures recommended by your clinician. Chest discomfort episodes may become less frequent in patients with stable angina who adhere to the plan. Regular monitoring helps your prescriber evaluate tolerability and whether adjustments are needed. Do not stop suddenly unless your clinician instructs you to, as abrupt changes can lead to symptom rebound.
Compare With Alternatives
Some people may do well on a different calcium channel blocker or a generic version. Two options to ask your prescriber about include:
- Nifedipine XR: a generic extended-release nifedipine product that provides once-daily control.
- Amlodipine: a long-acting calcium channel blocker often used for hypertension and angina.
For broader context, see our articles on blood pressure management, including Treat Hypertension and Bystolic Works, and medication combinations in Caduet Medication.
Pricing and Access
We offer Canadian pricing with transparent checkout and US options. To review Adalat XL price and availability, add your prescribed strength to your cart to view current details. Savings vary by product and quantity. For occasional site deals, visit our Promotions page. Orders Ships from Canada to US with careful pharmacy handling. Checkout is encrypted for your security.
Availability and Substitutions
Stock and manufacturers can change. If your preferred brand is unavailable, your prescriber may recommend a suitable alternative or a generic nifedipine extended-release option. Our pharmacists can coordinate with your clinician when a substitution is medically appropriate.
Patient Suitability and Cost-Saving Tips
The treatment may suit adults needing once-daily blood pressure control or chronic stable angina prevention. It may not be appropriate for those with severe hypotension, advanced aortic stenosis, or recent myocardial infarction unless a prescriber determines it is safe. Discuss liver issues, pregnancy or breastfeeding plans, and all other medicines you take. To lower out-of-pocket costs, consider longer fills when appropriate, combine refills for fewer fees, and set reminders so you do not miss doses. If you plan to Buy Adalat XL regularly, ask your prescriber about a multi-month prescription to reduce pharmacy trips.
Questions to Ask Your Clinician
- Is this the right calcium channel blocker for my goals?
- How should I time doses with my other medicines?
- What symptoms should prompt me to contact your office?
- Should I avoid specific foods, like grapefruit, or alcohol?
- How often should I check blood pressure at home?
- What signs of swelling or dizziness are concerning?
- Could a generic or different class be a better fit?
Authoritative Sources
Bayer (Manufacturer)FDA DailyMedHealth Canada Drug Product Database
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Can I split or crush the extended-release tablet?
No. Extended-release nifedipine tablets must be swallowed whole to preserve the controlled delivery system. Cutting, crushing, or chewing can release the full dose at once, raising the risk of low blood pressure, dizziness, or other adverse effects. If you have difficulty swallowing tablets, ask your prescriber or pharmacist about options. Do not change the form or switch products without guidance from a healthcare professional.
What foods or drinks should I avoid while taking it?
Avoid grapefruit and grapefruit juice, which can significantly increase nifedipine exposure through CYP3A interactions. Limit alcohol because it may worsen dizziness or flushing. Maintain a consistent routine with meals to help absorption. Keep well hydrated, and talk to your clinician about salt intake and overall diet for blood pressure management. If you take supplements or herbal products, review them with your pharmacist.
How quickly will blood pressure control improve?
Response varies by person. Some people notice early changes with consistent daily use, while full assessment often requires repeated readings over days to weeks. Your clinician may ask you to log home measurements at the same times each day. Do not adjust your dose on your own. If readings remain above your target or you feel unwell, contact your prescriber for guidance.
What are the most common side effects?
Headache, flushing, dizziness, ankle swelling, fatigue, and nausea occur in some people. These effects may be more noticeable when starting or after dose changes. Rise slowly from sitting or lying positions to reduce lightheadedness. Contact your healthcare professional if symptoms are severe, persistent, or include chest pain that is new or different, shortness of breath, or signs of an allergic reaction.
Can I take it with beta blockers or ACE inhibitors?
Combination therapy is common in hypertension. Calcium channel blockers can be used with beta blockers, ACE inhibitors, or ARBs under medical supervision. Your clinician will consider your blood pressure, heart rate, comorbidities, and potential interactions. Monitor for dizziness or swelling when therapies are combined. Always share an up-to-date medication list with your prescriber and pharmacist.
What should I do if I miss a dose?
If you forget a dose, take it when you remember the same day. If it is close to your next scheduled time, skip the missed dose and continue with your regular schedule. Do not take two doses at once. Setting phone alerts or using a pill organizer can help prevent future missed doses. If you frequently miss doses, speak with your clinician about strategies to simplify your routine.
Is generic nifedipine ER equivalent to the brand?
Approved generics must meet bioequivalence standards to the reference product. Many patients do well when using a generic version. However, not all products share identical release mechanisms, and individual tolerability can vary. If you switch to a different manufacturer and notice changes in symptoms or side effects, inform your prescriber. Your pharmacist can help identify the specific product you receive.
