Adalat XL® Extended-Release Nifedipine Tablets for Blood Pressure

What Adalat XL® Is and How It Works

Adalat XL® is the extended-release form of nifedipine, a calcium channel blocker used to lower high blood pressure and help prevent chronic stable angina. It comes as once-daily tablets, commonly 30 mg and 60 mg strengths, with a 90 mg strength available in some markets. YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba; prescriptions are reviewed by licensed pharmacists before dispensing. Many patients choose an adalat xl online purchase to reduce their adalat xl cost, including people managing adalat xl without insurance.

Each Adalat XL tablet uses a gastro-intestinal therapeutic system (GITS) that releases nifedipine slowly throughout the day. The medicine relaxes arterial smooth muscle. This widens blood vessels, lowers peripheral resistance, and reduces blood pressure. It also improves coronary blood flow, which can lessen the frequency of angina episodes. Swallow tablets whole; do not split, crush, or chew.

We work with licensed, vetted international partner pharmacies to supply authentic brand medications from a broad catalog at pricing that helps keep treatment affordable.

Dosage and Usage

• Typical adult starting dose: 30 mg once daily. Your prescriber may adjust based on response.
• Titration: increases are often made in 7–14 day intervals. Many people use 60 mg once daily; some may require 90–120 mg/day.
• Take at the same time each day, with or without food. Be consistent with food intake.
• Do not crush, split, or chew. The tablet shell may pass in your stool; this is expected.
• Avoid grapefruit or grapefruit juice, which can raise nifedipine levels.
• Missed dose: take as soon as you remember the same day. If it is almost time for your next dose, skip the missed dose. Do not double.
• Do not stop Adalat XL suddenly unless your prescriber directs you to do so.
• If you are sensitive to dizziness, rise slowly from sitting or lying positions.

• Store at 15–30 °C (59–86 °F) in a dry place, away from light.
• Keep tablets in the original bottle or blister until use to protect from moisture.
• Do not store in a bathroom. Avoid heat above 30 °C and freezing conditions.
• When traveling, carry your medication in your hand luggage with the pharmacy label.
• Pack an extra few days of tablets in case of travel delays.
• Keep out of reach of children and pets.

Benefits and Savings

Adalat XL helps reduce systolic and diastolic blood pressure and can improve exercise tolerance in stable angina. The once-daily extended-release design supports steady control with fewer peaks and troughs. Many patients find this convenient compared to multiple daily doses.

Ordering from Canada can lower your adalat price. People often compare the adalat xl 30 mg price and the adalat xl 60mg price to choose the most economical strength directed by their prescriber. You can buy adalat xl online and often save 60–80% versus typical U.S. prices. These savings can help if you are paying adalat xl cash price or adalat xl out of pocket. We also see consistent savings for those seeking adalat xl without insurance.

Multi-month fills can reduce per-month costs, and occasional adalat xl discount or adalat xl sale events may apply. Bulk options can help if your prescriber writes a 90-day supply. We can send friendly reorder reminders before you run low. For periodic deals, visit our promotions page for an adalat xl coupon.

Side Effects and Safety

Adalat xl 30mg side effects and those seen with higher strengths are generally similar and often improve as your body adapts.

• Headache or flushing
• Dizziness or lightheadedness
• Peripheral edema (ankle or foot swelling)
• Fatigue
• Palpitations or a fast heartbeat
• Nausea, heartburn, or constipation
• Facial warmth or redness
• Gingival (gum) tenderness or overgrowth with long-term use

Serious effects are uncommon but can include marked hypotension, worsening angina or, rarely, myocardial infarction soon after starting or increasing the dose, severe edema, allergic reactions, or elevated liver enzymes. Use caution in significant aortic stenosis, heart failure, hepatic impairment, or if you are pregnant or nursing. Many drugs affect nifedipine levels; strong CYP3A4 inhibitors (for example, certain azole antifungals or macrolide antibiotics) can raise concentrations. Avoid grapefruit. Strong CYP3A4 inducers (such as rifampin) can reduce efficacy.

Onset Time

Blood pressure lowering begins within the first doses. You may see early changes in 24–48 hours. The full effect often develops over 1–2 weeks as the dose is optimized. For chronic stable angina, fewer episodes can appear within several days, with further gains as your maintenance dose is established.

Compare With Alternatives

Amlodipine is another once-daily dihydropyridine calcium channel blocker. It has a long half-life and smooth control. Some people report less flushing with amlodipine but similar rates of ankle swelling. Either option may be appropriate depending on your history and response.

Diltiazem extended-release is a non-dihydropyridine calcium channel blocker. It lowers blood pressure and slows heart rate, which can help certain arrhythmias. It is not interchangeable with nifedipine and has different interaction and side-effect profiles.

Felodipine is another once-daily dihydropyridine option. Like Adalat XL, it lowers blood pressure by relaxing arterial smooth muscle. Choice among these agents depends on tolerability, comorbidities, and prescriber preference.

Combination Therapy

• ACE inhibitor or ARB plus Adalat XL: common pairing for hypertension; supports additive blood pressure reduction.
• Thiazide diuretic plus Adalat XL: can improve control and may help reduce edema.
• Beta-blocker plus Adalat XL: used in angina or certain cardiac histories; monitor for hypotension.
• Nitrates plus Adalat XL: may be used for chronic angina; dosing should be spaced to limit headache and hypotension.
• Statins and other chronic medicines: check for interactions; dose adjustments may be needed.

Patient Suitability and Cost-Saving Tips

Adalat XL is intended for adults with hypertension and for prevention of chronic stable angina symptoms. It is not for hypertensive emergencies. It may not be suitable if you have severe aortic stenosis, cardiogenic shock, a known nifedipine allergy, or significant hepatic impairment. Older adults may need slower titration. Report persistent swelling, severe dizziness, or chest pain changes promptly.

To lower your adalat xl cost, consider a 90-day prescription if appropriate, which often qualifies for lower per-month pricing and adalat xl bulk buy promotions. Compare the adalat xl 60mg price with two 30 mg tablets only if your prescriber approves an equivalent regimen. Set reorder reminders so you have time for prompt, express shipping. These steps can help when paying adalat xl uninsured or seeking adalat xl without insurance.

Authoritative Sources

See the Health Canada Drug Product Database entries for Adalat XL: Health Canada Drug Product Database.

Review U.S. prescribing information for nifedipine extended-release products via the FDA database: FDA Drug Label Search: Nifedipine Extended-Release.

For background on nifedipine pharmacology and class effects, consult your prescriber or pharmacist, and review manufacturer materials where available.

Order Adalat XL® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This material is educational and does not replace advice from your healthcare professional. Always follow your prescriber’s directions and the pharmacy label.