Adcirca® Tablets for Pulmonary Arterial Hypertension

Adcirca is a prescription tablet used to help manage pulmonary arterial hypertension in adults. This page explains how it works, who it may suit, and how to access it with US delivery from Canada. It also covers safety basics and ways to pay without insurance.

What Adcirca Is and How It Works

Adcirca® contains tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It helps relax blood vessels in the lungs, which can reduce pulmonary vascular resistance. That effect may improve your exercise capacity and symptoms when used as directed by your prescriber.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Many patients receive Tadalafil 20 mg tablets for PAH under a clinician’s supervision. The medicine works by blocking PDE5 in the pulmonary circulation. This can support better blood flow in the lungs. Follow your prescriber’s instructions and the official label for complete details.

Learn more about the condition in our category guide: Pulmonary Hypertension.

Who It’s For

This treatment is prescribed for adults diagnosed with pulmonary arterial hypertension, WHO Group 1. It may be used alone or with other PAH therapies when recommended by a specialist. Some people may instead be suitable for Cardiovascular options within the same class.

Certain people should avoid it. Those taking any form of nitrates should not use tadalafil due to the risk of severe low blood pressure. A prescriber may consider alternatives if you have severe liver disease, significant kidney impairment, very low resting blood pressure, recent stroke or heart attack, or if you take riociguat. Your healthcare professional will assess benefits and risks.

Some may be switched to Generic tadalafil 20 mg PAH when appropriate and available. Decisions depend on your diagnosis, other medicines, and national labelling.

Dosage and Usage

The usual adult regimen for Adcirca tadalafil 20 mg is two tablets taken once daily, with or without food, at about the same time each day. Swallow tablets whole with water. Do not split, crush, or chew. If your prescriber advises a different schedule due to kidney or liver considerations, follow that guidance and the official product information.

General administration tips:

• Consistent timing: take it at the same time daily
• Food: can be taken with meals or on an empty stomach
• Alcohol: limit intake to reduce dizziness or blood pressure drops
• Grapefruit: may increase levels; ask your clinician before use
• Do not combine with other PDE5 inhibitors

Always defer to your prescriber and the package insert for individualized instructions.

Strengths and Forms

We offer Adcirca tablets 20 mg for adult use as prescribed. Availability, pack sizes, and manufacturers may vary based on supply and jurisdiction.

Missed Dose and Timing

If you miss a daily dose, take it when you remember, unless it is close to the next dose. If it is near your next scheduled time, skip the missed dose. Do not take extra tablets to make up for a missed dose. If you miss doses often, speak with your prescriber about strategies to stay on track.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep them in the original labeled container with the child-resistant cap tightly closed. Store out of reach of children and pets. Do not use tablets past the expiry date.

For travel, carry your medicine in hand luggage with the prescription label visible. A copy of your prescription or a recent pharmacy receipt can help during security checks. Avoid storing tablets in a parked car or in direct sunlight. If crossing borders, keep your documents handy and pack only what you need plus a small buffer as permitted.

Benefits

This therapy can support improved exercise capacity and symptom relief in PAH. Once-daily dosing may simplify routines compared with multiple-dose regimens. It can be used as monotherapy or part of a combination plan when recommended by a specialist. Discuss goals with your clinician and keep regular follow-ups to monitor response.

For a deeper class overview, see our article What Is Tadalafil.

Side Effects and Safety

Common effects can include:

• Headache or flushing
• Indigestion or stomach discomfort
• Back pain or muscle aches
• Nasal congestion
• Dizziness

Serious effects are uncommon but can include sudden vision or hearing changes, chest pain, severe dizziness or fainting, prolonged or painful erections, or allergic reactions. Seek urgent care if severe symptoms occur. Low blood pressure risk increases with nitrates, riociguat, excessive alcohol, or certain antihypertensives. If you also use insulin or sulfonylureas, discuss hypoglycaemia prevention strategies, as lightheadedness may complicate recognition.

Read more on class tolerability in Tadalafil Side Effects.

Drug Interactions and Cautions

Important interactions can occur with:

• Nitrates of any kind (contraindicated)
• Riociguat (avoid combination)
• Strong CYP3A4 inhibitors (for example, ketoconazole, ritonavir)
• CYP3A4 inducers (for example, rifampin), which may reduce effect
• Alpha-blockers and antihypertensives (additive blood pressure lowering)
• Excess alcohol and grapefruit products

Tell your prescriber about all medicines, vitamins, and herbal products you use. Do not start or stop therapies without professional guidance.

What to Expect Over Time

Your clinician may track exercise tolerance, symptoms, and vital signs over time. It can take steady daily use and routine follow-up to understand how you are responding. Keep a simple diary of activity level, breathlessness, and any side effects. Bring it to appointments. If your plan includes other PAH therapies, your prescriber will set realistic goals and adjust as needed according to the label and guidelines.

Compare With Alternatives

Within PDE5 inhibitors, sildenafil is another approved option in PAH care. Some patients may remain on the class you start with; others may switch or combine therapies under specialist care.

We offer Sildenafil and Tadalafil. For a broader comparison, see Tadalafil vs Sildenafil. Your clinician will tailor choices to your condition, other medicines, and monitoring needs.

Pricing and Access

The Adcirca 20 mg price can vary by manufacturer and pack size. Check current availability on this page to see options aligned with Canadian pricing. We cannot post dollar amounts here, but our checkout shows live totals before you confirm.

For many, the Adcirca 20 mg cash price may be lower than local rates. We provide transparent taxes and fees during checkout. You can review all charges before you pay. We support US delivery from Canada with a valid prescription, and our site uses encrypted checkout for your security. If you are looking for seasonal offers, visit Promotions when available.

Availability and Substitutions

Supply can change. If a specific pack is unavailable, your prescriber may recommend a suitable alternative or a comparable generic. Substitution depends on your prescription, local rules, and professional judgment. We do not promise restock dates.

Patient Suitability and Cost-Saving Tips

Good candidates are adults with a confirmed PAH diagnosis under specialist care. It may not suit those with severe liver problems, advanced kidney disease, unstable cardiovascular status, or anyone using nitrates or riociguat. Always discuss your medical history, including eye conditions such as NAION, before starting therapy.

Cost-saving ideas you can discuss with your prescriber:

• Multi-month fills: fewer refills, often lower per-tablet costs
• Refill reminders: set calendar alerts to stay on schedule
• Combine orders: reduce separate courier fees when possible
• Ask about generics: Tadalafil 20 mg without insurance may reduce out-of-pocket expenses
• Consistent pharmacy: keep records in one place for safety checks

Questions to Ask Your Clinician

• How does this PDE5 inhibitor fit into my overall PAH plan?
• Which symptoms should trigger a call or visit right away?
• Do my other medicines raise the risk of low blood pressure?
• Could a generic be suitable for me now or later?
• How often should I have follow-up tests or exams?
• What lifestyle steps support my treatment goals?

Authoritative Sources

Adcirca (Official Site)DailyMed: Adcirca (tadalafil) TabletsHealth Canada DPD: Adcirca

Ready when you are. Order Adcirca 20 mg with prompt, express shipping and US delivery from Canada, with temperature-controlled handling when required. Prescription required. This information is educational and not a substitute for professional medical advice. Always follow your prescriber’s directions and the official label.