Advair® HFA Inhaler for Asthma

Advair® HFA is a prescription inhaler for long-term asthma control. It combines an inhaled corticosteroid and a long-acting bronchodilator to help reduce symptoms and flares. This page explains how it works, who it may suit, and how to use it, with US delivery from Canada and options if you pay without insurance.

What Advair Is and How It Works

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The inhaler contains fluticasone propionate and salmeterol. Fluticasone reduces airway inflammation. Salmeterol helps keep airways open for many hours. Together, they provide maintenance control for asthma when taken regularly. This is not a rescue inhaler; keep a fast-acting reliever for sudden symptoms.

As a combination fluticasone salmeterol HFA inhaler, it is designed for twice-daily use. It may improve breathing comfort, reduce night symptoms, and lower the risk of exacerbations when used as directed. Results depend on consistent use and proper technique.

Learn more about asthma basics in our guide What Is Asthma, and explore the Asthma category for related therapies.

Who It’s For

This medicine is indicated for the maintenance treatment of asthma in patients for whom a combination therapy is appropriate. It is not meant for acute bronchospasm or sudden breathing problems. People with a history of hypersensitivity to any component should not use it. Discuss medical history with your healthcare professional, especially if you have cardiovascular disease, arrhythmias, hyperthyroidism, seizures, liver issues, active infections, or a history of tuberculosis.

Advair HFA is not approved as initial therapy for rapidly deteriorating asthma. It is not indicated for COPD; see our COPD page and broader Respiratory category for options tailored to chronic bronchitis and emphysema.

Dosage and Usage

Typical labeling calls for two inhalations twice daily, about 12 hours apart. Use it regularly even when you feel well. Do not use it to relieve sudden breathing trouble; use a rescue inhaler instead.

Before first use, prime the canister by spraying into the air as directed in the leaflet. Re-prime if not used for several weeks or if dropped. Shake well before each inhalation. Exhale fully, place the mouthpiece, inhale slowly and deeply while pressing the canister, then hold your breath for up to 10 seconds. Rinse your mouth and spit after each dose to reduce the chance of oral thrush.

The Advair HFA 120 dose inhaler includes a dose counter to help track remaining puffs. Do not exceed prescribed inhalations. If asthma seems worse, contact your prescriber rather than increasing use on your own. Review technique periodically with a clinician or pharmacist; consider a spacer if recommended.

For broader management tips, see our article Bronchitis And COPD and seasonal wellness content like Healthy Lung Month.

Strengths and Forms

This HFA metered-dose inhaler is available by prescription in multiple strengths. Common options include 45/21, 115/21, and 230/21 micrograms of fluticasone propionate/salmeterol per actuation. Each canister typically provides 120 metered inhalations, though availability can vary by region and supply.

Missed Dose and Timing

If you miss a scheduled dose, take the next dose at the regular time. Do not double up or take extra puffs to make up for a missed dose. Keep doses evenly spaced, about 12 hours apart. Consistency supports better asthma control.

Storage and Travel Basics

Store at room temperature as directed in the official label. Keep the canister capped, away from heat, open flame, and direct sunlight. Do not puncture or incinerate the canister. Protect from freezing. Keep out of the reach of children and pets.

For travel, carry your inhaler and rescue medicine in your hand luggage. Keep products in their original packaging with the prescription label. Bring a spacer if prescribed. Pack an extra inhaler if your prescriber recommends it, and note the dose counter before trips to avoid running out.

For ongoing respiratory wellness, explore Respiratory Care Week 2025 content and our Seasonal Allergies guide if allergic triggers affect your asthma.

Benefits

This treatment can help improve lung function and reduce asthma symptoms when used consistently. It may lower the number of exacerbations and night awakenings compared with inhaled steroid alone for some patients. The pressurized HFA format suits people who prefer a metered-dose inhaler over a dry powder device. A built-in counter helps you track remaining inhalations, supporting adherence and planning.

Side Effects and Safety

• Throat irritation or hoarseness
• Cough
• Headache
• Nausea
• Oral thrush
• Muscle or bone aches

Serious but less common effects can include paradoxical bronchospasm, hypersensitivity reactions, effects on heart rhythm, lowered potassium, elevated blood sugar, glaucoma or cataracts, and adrenal suppression with higher steroid exposure. Seek urgent care for severe breathing trouble, hives, swelling, or chest pain. Rinse your mouth after dosing and report persistent hoarseness or white patches.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, cobicistat, or ritonavir can raise steroid exposure; your prescriber may avoid or monitor such combinations. Other long-acting beta-agonists should not be used together with this medicine. Beta-blockers may reduce bronchodilator effects. Diuretics that lower potassium, tricyclics, or MAOIs may require caution. Tell your clinician about all medicines, vitamins, and herbal supplements you take.

What to Expect Over Time

Control improves with steady, correct use. Some people notice easier breathing within days, while full benefit may build with regular dosing. You should still keep a rescue inhaler for sudden symptoms. Your prescriber may adjust your regimen over time based on control, inhaler use, and triggers. Do not stop this therapy abruptly without medical guidance.

Compare With Alternatives

Other maintenance inhalers combine an inhaled steroid with a long-acting bronchodilator. Budesonide/formoterol, available as Symbicort, can be considered in some plans. Fluticasone furoate/vilanterol, available as Breo Ellipta, is another option for certain patients. Dry powder versions such as Advair Diskus exist for those who prefer a DPI format. Your clinician can suggest the best fit for your technique and goals.

Pricing and Access

We offer Canadian pricing for brand-name asthma controllers with reliable US fulfilment. Check the Advair HFA inhaler price on this page to compare package options. To reduce out-of-pocket spending, see whether multi-month fills offer better value. If coupons are available, we list them on our Promotions page.

US residents can order with confidence as it Ships from Canada to US. If you prefer a non-branded search term, you can order fluticasone salmeterol HFA once your prescription is uploaded. We support encrypted checkout and clear billing so you can plan costs effectively.

Availability and Substitutions

Supply can vary by strength and region. There is currently no widely approved generic fluticasone salmeterol HFA inhaler in the US; your prescriber may recommend a therapeutically similar alternative if this product is unavailable. Suitable options may include other ICS/LABA inhalers or a change in device type based on your inhalation technique.

Patient Suitability and Cost-Saving Tips

This therapy may suit people with persistent asthma who benefit from both an inhaled corticosteroid and a long-acting bronchodilator. It is not appropriate for acute relief, sudden worsening asthma, or for those with known hypersensitivity to ingredients. Patients with certain heart conditions, active infections, or ocular issues should review risks with a clinician.

To manage costs, consider 90-day refills when appropriate, align refills with clinic visits, and set reminders for reordering before the counter nears zero. If paying cash, compare the Advair HFA cash price across package sizes. Keep your prescription current to avoid delays. For lung health topics year-round, see Lung Cancer Awareness Month and our feature on Respiratory Care Week 2025.

Questions to Ask Your Clinician

• My current severity: is a combination inhaler appropriate now?
• Which strength and device suit my inhalation technique?
• How should I adjust my plan during colds or allergy season?
• What signs mean I need a review or step-up in therapy?
• Which rescue inhaler should I carry and how often can I use it?
• Could interactions with my medicines affect safety or control?

Authoritative Sources

FDA DailyMed: Fluticasone Propionate and Salmeterol Inhalation Aerosol

Health Canada DPD: Advair HFA

Manufacturer Resources

Ready to get started? Upload your prescription and complete checkout for express US shipping from Canada, with temperature-controlled handling when required. This information is not a substitute for professional medical advice; always follow your prescriber’s instructions and the official label.