Afinitor® Tablets for Certain Cancers

Afinitor is an oral targeted therapy used for certain advanced cancers and tuberous sclerosis complex conditions. It contains everolimus, which blocks a growth pathway inside cancer cells. People often compare the Afinitor 5 mg price without insurance and look for clear guidance, including US delivery from Canada.

What Afinitor Is and How It Works

Afinitor® contains everolimus, an mTOR inhibitor. By inhibiting the mTOR pathway, it can slow cell growth, reduce blood vessel formation in tumors, and help control disease progression in select conditions. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This medicine is taken by mouth once daily on a regular schedule. Swallow tablets whole with a glass of water. Take it the same way every day, either consistently with food or consistently without food. The treatment can interact with certain medicines and foods; see Interactions below for an overview and always follow your prescriber’s instructions.

Patients sometimes ask about Afinitor 5 mg Canadian pricing, which varies by strength and supply. You can review pricing details in the section below and compare options with your prescriber.

For background learning on targeted and immune-based approaches, you may also find our article Immunotherapy For Cancer helpful, though this medicine is not an immunotherapy.

Who It’s For

This therapy is used in adults for certain advanced or metastatic cancers, including hormone receptor–positive, HER2-negative breast cancer (in combination with an aromatase inhibitor such as exemestane), renal cell carcinoma after prior VEGF-targeted treatment, and progressive, well-differentiated, nonfunctional neuroendocrine tumors of pancreatic, gastrointestinal, or lung origin. It also treats tuberous sclerosis complex–associated subependymal giant cell astrocytoma and renal angiomyolipoma when surgery is not required.

People with severe liver problems, uncontrolled infections, or known hypersensitivity to everolimus or related medicines should avoid use unless a prescriber determines benefits outweigh risks. Your clinician will review your full history, including vaccinations, kidney function, blood counts, and any planned surgery.

For condition-specific browsing, see our categories for Breast Cancer and Kidney Cancer.

Dosage and Usage

Tablets are taken once daily at about the same time each day. Take them consistently with food or consistently without food, because changing around meals may change absorption. Swallow whole; do not crush, split, or chew. If you have difficulty swallowing, ask your prescriber about the dispersible formulation used in specific cases.

Do not take with grapefruit or grapefruit juice. Avoid St. John’s wort. Tell your clinician about all prescription and nonprescription products, vitamins, and herbal supplements. If you are instructed to pause treatment before surgery, follow the prescriber’s guidance on when to stop and restart. Your dose may be adjusted if you have liver impairment or if you take certain interacting medicines.

Ordering is prescription-based. If your prescriber has recommended this therapy, you can Order Afinitor 5 mg online through our pharmacy after we receive and verify your prescription.

Strengths and Forms

Availability can vary by country and supply. Common presentations include:

• Tablets: 2.5 mg, 5 mg, 7.5 mg, 10 mg
• Dispersible tablets for oral suspension (often used for TSC-related indications): 2 mg, 3 mg, 5 mg

Strength selection depends on your indication, tolerability, liver function, and any interacting medicines. If you have questions about the Afinitor 5 mg tablets price for a specific supply length, see Pricing and Access.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember the same day. If it is close to the time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at once to make up for a missed tablet. If vomiting occurs after a dose, do not take an extra tablet; resume your regular schedule.

Storage and Travel Basics

Store tablets in the original packaging at room temperature, away from moisture and excessive heat. Keep out of reach of children and pets. Do not remove tablets from the blister until ready to take. When traveling, carry your medicine in hand luggage together with a copy of your prescription and your prescriber’s contact information. A simple pill organizer can help with daily schedules, but keep the original box for labeling and security checks.

For air travel, allow extra time at screening and keep a list of all medicines in your carry-on. If your clinician changes your dose, ensure your updated instructions travel with you. Use a reminder system so you take it at the same time each day.

Benefits

This targeted therapy offers an oral option that may slow cancer growth in specific settings. It can be used in combination with other treatments, such as hormone therapy for certain breast cancers, or as a single agent in approved indications. Once-daily oral dosing avoids clinic infusion visits. The treatment has a well-described safety profile, and healthcare professionals can monitor labs and adjust dosing when needed.

Educational overviews on disease types and care planning can support discussions with your clinician. For a broad primer, explore Common Types Of Cancer.

Side Effects and Safety

• Mouth sores or ulcers
• Rash or dry skin
• Diarrhea or nausea
• Fatigue or weakness
• Swelling in hands or feet
• Cough or shortness of breath
• Changes in blood sugar or lipids
• Headache or dizziness
• Infections, including respiratory or urinary

Serious risks can include noninfectious pneumonitis, severe infections, kidney problems, poor wound healing, bleeding, and rare hypersensitivity reactions. Report new or worsening cough, chest discomfort, fever, painful mouth sores, or decreased urination promptly. Your prescriber may monitor blood counts, kidney function, blood sugar, lipids, and, when relevant, drug levels to manage safety.

Drug Interactions and Cautions

Everolimus is affected by CYP3A4 and P-glycoprotein. Strong inhibitors (for example, ketoconazole, itraconazole, clarithromycin, certain antivirals) can raise levels; strong inducers (such as rifampin or some anticonvulsants) can lower levels. Grapefruit products can change exposure and should be avoided. Live vaccines may not be appropriate during treatment. Alcohol may worsen mouth irritation or stomach upset for some people.

Tell your clinician about pregnancy plans, contraception, or breastfeeding. This medicine may harm an unborn baby; discuss reliable birth control and timing for family planning.

What to Expect Over Time

During the first weeks, mouth soreness can occur; your healthcare professional may recommend supportive mouth rinses or dose adjustments if needed. Energy levels may vary. Periodic blood tests and imaging help assess how you are responding. Many people find routines helpful: take the tablet at the same time daily, log side effects, and keep a list of all medicines. Stay in close contact with your care team if symptoms change or if you start or stop any other therapy.

Compare With Alternatives

Prescribers may consider other targeted therapies depending on cancer type and prior treatments. For renal cell carcinoma, VEGF tyrosine kinase inhibitors such as Inlyta may be used in certain sequences. For specific breast cancers with PIK3CA mutations, a PI3K inhibitor like Piqray might be discussed. Choice depends on tumor features, prior response, side effect profiles, and clinician judgment.

Some patients also ask about Everolimus 5 mg generic price when evaluating therapy choices. Generic availability and coverage can differ; your prescriber and pharmacy team can help you compare options.

Pricing and Access

We list current options so you can review the Afinitor 5 mg cash price alongside other strengths and supplies. You can also compare Everolimus 5 mg price and discuss coverage with your prescriber or insurer. If you are looking for coupons or seasonal offers, check our Promotions page for any current savings.

Orders are processed with prescription review, encrypted checkout, and careful packing. You can request refills and ship to your US address with US delivery from Canada. Contact our team if you need help aligning your refill schedule with clinic visits or lab monitoring.

Availability and Substitutions

Supply can vary by strength or formulation. If your requested strength is temporarily unavailable, your prescriber may recommend an equivalent total daily dose using different tablet strengths, or suggest a suitable alternative based on your indication. Ask how this affects your schedule and monitoring. If you are researching the Afinitor 5 mg tablets price while considering a substitution, confirm the strength and total days’ supply so comparisons are accurate.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with specific cancers after defined prior treatments, or people with certain tuberous sclerosis complex–related conditions. It may not be right for those with uncontrolled infections, severe liver disease, or who cannot avoid interacting medicines. For affordability, consider longer supplies if appropriate, align refills with clinic visits, and set calendar reminders. Discuss manufacturer support programs with your prescriber’s office if available in your region.

Multi-month fills can reduce per-fill fees and help you maintain consistent therapy. If you plan travel, order ahead and keep extra time for any prescription clarifications. Your clinician can help decide quantity and follow-up timing. Keep records of previous reactions and lab trends; share them at each visit.

Questions to Ask Your Clinician

• How does this treatment fit with my overall plan?
• Which side effects should I report immediately?
• Do I need lab tests before and during treatment?
• Are there medicines, foods, or supplements I must avoid?
• How long should I continue before reassessing?
• What are my options if I do not tolerate this medicine?

Authoritative Sources

For complete, up-to-date information, consult these official resources:

• Manufacturer: Novartis Afinitor
• FDA Prescribing Information (DailyMed)
• Health Canada Drug Product Database

Ready to proceed? Place your order for prompt US delivery from Canada. This page is informational and does not replace your prescriber’s advice.