Aptiom® (eslicarbazepine acetate) Tablets for Partial-Onset Seizures

What Aptiom® Is and How It Works

Aptiom® (eslicarbazepine acetate) is an oral antiepileptic used to treat partial-onset (focal) seizures. It is approved as monotherapy or add-on therapy in adults and in pediatric patients when prescribed. Dosing is once daily. Many people compare Aptiom cost when planning long-term seizure care, and we aim to help with clear pricing. YouDrugstore is a licensed Canadian pharmacy in Manitoba that meets Canadian pharmacy standards. Our pharmacists review prescriptions before dispensing, and our team offers friendly customer-service chat during posted office hours.

Eslicarbazepine is a prodrug. Your body converts it to eslicarbazepine, which blocks voltage-gated sodium channels. This stabilizes overactive neurons and reduces seizure spread. Tablets are available in several strengths to support careful titration.

We work with licensed, vetted partner pharmacies internationally to source authentic brand medicines and a broad selection at fair prices.

Dosage and Usage

Your prescriber will set your plan. Typical adult dosing follows a simple once-daily schedule. Tablets can be taken with or without food and swallowed whole.

• Start: 400 mg once daily for one week.
• Titrate: increase by 400 mg daily each week as directed.
• Maintenance: 800 to 1,200 mg once daily for many adults.
• Some patients may use up to 1,600 mg once daily if advised.

Pediatric dosing is weight-based and once daily. The prescriber provides the exact dose and titration steps.

Missed dose guidance:

• If you miss a dose, take it when remembered the same day.
• If it is near the next dose, skip the missed dose. Do not double up.
• If you miss more than one dose, ask your prescriber for advice.

Do not stop suddenly. Stopping abruptly can increase seizure risk. If a change is needed, your prescriber will taper the dose.

Storage and travel:

• Store at 15–30°C (59–86°F) in a dry place.
• Keep tablets in the original container with the label.
• When traveling, carry doses in your hand luggage.
• Keep away from moisture and out of children’s reach.

Driving and tasks: dizziness and drowsiness can occur. Know how you react before driving, using machinery, or climbing.

Benefits and Savings

Aptiom® offers once-daily dosing, which may fit better into daily routines. It is effective for partial-onset seizures as a single agent or as part of combination therapy. Some patients experience fewer drug interactions than with older sodium-channel agents.

Ordering from YouDrugstore is simple. We are a licensed Canadian pharmacy with pharmacist review of every prescription. You can order online or by phone where available, and our team is ready to help during posted hours.

Buying through Canadian pharmacy services often brings 60–80% savings versus typical US retail pricing. Multi-month supplies can lower the per-month cost further, when appropriate for your prescription.

Side Effects and Safety

Many side effects are mild and improve with dose adjustments. Contact your prescriber if symptoms persist or worsen. Seek urgent care for signs of a severe reaction.

• Common: dizziness, sleepiness, headache, nausea, vomiting, fatigue, balance problems, blurred or double vision.
• Nervous system: difficulty concentrating, tremor, coordination issues.
• Gastrointestinal: stomach pain, diarrhea, constipation.
• Hyponatremia (low sodium): confusion, seizures, headache, nausea, muscle cramps; risk may rise with diuretics or if older.
• Allergic reactions and rash: hives, swelling, trouble breathing; rare severe skin reactions (SJS/TEN) or DRESS.
• Mood changes: irritability, depression, suicidal thoughts; contact a clinician if mood or behavior changes.
• Liver enzyme changes: dark urine, yellowing skin/eyes, upper right abdominal pain.
• Eye events: sudden vision changes should be assessed promptly.

Drug interactions:

• Eslicarbazepine may lower the effectiveness of hormonal contraceptives. Use reliable non-hormonal backup.
• It can raise phenytoin levels. Monitoring may be needed.
• It may reduce levels of some medicines metabolized by CYP3A. Your prescriber will review your list.
• Combining with oxcarbazepine is generally avoided due to cross-reactivity and sodium effects.

Tell your prescriber about kidney or liver issues, prior reactions to carbamazepine or oxcarbazepine, and all medicines and supplements. Dose reduction is often needed if kidney function is reduced (CrCl < 50 mL/min).

Onset Time

Eslicarbazepine reaches steady state in about 4 to 5 days. Some people notice fewer seizures as the dose is titrated over the first few weeks. The full effect is usually seen after reaching the maintenance dose and allowing time to stabilize.

Compare With Alternatives

Several antiepileptics can treat partial-onset seizures. Choice depends on seizure control, side effects, other medicines, and personal factors.

Levetiracetam (Keppra) is widely used for focal seizures and is often well tolerated. It is dosed twice daily, with behavioral side effects in some patients. Lacosamide (Vimpat) modulates sodium channels differently and is dosed twice daily; it may affect the PR interval on ECG. Oxcarbazepine (Trileptal) is an older sodium-channel agent dosed twice daily, with a higher rate of hyponatremia and potential cross-reactivity with carbamazepine.

Your clinician will compare efficacy, adverse effects, dosing schedules, interactions, and costs when recommending a regimen.

Combination Therapy

Aptiom® can be used alone or with other antiepileptics. Common add-on partners include levetiracetam, topiramate, and lamotrigine. Combination therapy aims to improve seizure control while balancing side effects.

Because eslicarbazepine may reduce hormonal contraceptive effectiveness, consider non-hormonal backup. Alcohol can worsen dizziness and seizure risk. Combining with oxcarbazepine is usually avoided. If you use phenytoin, levels may rise, so monitoring may be needed. Do not adjust doses on your own; your prescriber will guide any changes.

Patient Suitability and Cost-Saving Tips

Aptiom® may suit adults and appropriately selected pediatric patients with partial-onset seizures who benefit from once-daily dosing. Caution is needed with a history of severe rash to related drugs, low sodium, significant kidney impairment, or liver disease. People of certain Asian ancestries may have a higher risk of severe skin reactions with related agents; your prescriber may consider genetic risk in context.

Ways to manage costs:

• Ask your prescriber if a multi-month supply fits your plan; it can lower the monthly price.
• Turn on reorder reminders so you do not miss a dose or rush a refill.
• Strengths 400 mg, 600 mg, and 800 mg are available; your clinician can choose the most efficient pack size.
• Generic eslicarbazepine acetate may be available in some markets; availability varies by strength and supplier.

See our Promotions page for current Aptiom coupon and bulk options.

YouDrugstore offers brand and generic medicines at Canadian prices, with caring support from our team. We ship to the US and provide clear guidance on documentation for customs when needed.

Authoritative Sources

Review trusted information before starting or changing therapy. See the Aptiom patient website (manufacturer), the FDA Prescribing Information, and the DailyMed Medication Guide.

Order with confidence from YouDrugstore, a licensed Canadian pharmacy. Our pharmacists review every prescription, and our customer-service chat is available during posted hours. We offer prompt, express shipping to the US, with careful packaging to protect your order.

Disclaimer: This page is educational and does not replace medical advice. Always follow your prescriber’s directions and the patient leaflet. Report side effects to your clinician. In an emergency, call local emergency services right away.