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Aptiom

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Price range: $572.99 through $1,065.99

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Aptiom (eslicarbazepine acetate) is an anticonvulsant used to treat partial-onset seizures in adults and children aged 4 years and older with epilepsy. It works by stabilising electrical activity in the brain, helping to prevent seizures. Aptiom is typically used as a monotherapy or adjunct therapy, depending on the clinical context.

Benefits

  • Helps reduce frequency and severity of partial-onset seizures
  • Can be used alone or in combination with other antiepileptic drugs
  • Once-daily dosing improves convenience and adherence
  • Approved for use in both adults and children (4 years and older)
  • Available in tablet form, with a liquid suspension available for paediatric use

Dosage

  • Adults (monotherapy or adjunct): Start at 400 mg once daily; may increase to 800–1,200 mg/day
  • Children (≥4 years): Dose based on weight; typically 5 mg/kg to 10 mg/kg once daily, up to 1,200 mg/day
  • Tablets should be taken once daily, with or without food
  • Dose adjustments may be necessary in patients with kidney impairment
  • Gradual titration is recommended to reduce the risk of side effects

Warnings and Precautions

  • May cause dizziness, drowsiness, or coordination problems—caution when driving or operating machinery
  • Risk of serious skin reactions such as Stevens-Johnson syndrome
  • May affect sodium levels—monitor for signs of hyponatraemia (e.g., confusion, seizures)
  • Use with caution in patients with liver or kidney disease
  • May increase the risk of suicidal thoughts or behaviour
  • Not recommended during pregnancy unless clearly necessary—may affect foetal development

Usage Instructions

  • Take Aptiom exactly as prescribed, once daily
  • Can be taken with or without food
  • Swallow tablets whole; do not crush or chew
  • Do not stop taking suddenly—sudden withdrawal may trigger seizures
  • If a dose is missed, take it as soon as possible unless it’s close to the next dose

Storage Information

  • Store at room temperature between 15°C and 30°C (59°F and 86°F)
  • Protect from moisture and light
  • Liquid formulation should not be frozen
  • Keep out of reach of children

Common Side Effects

  • Dizziness or drowsiness
  • Headache
  • Nausea or vomiting
  • Double vision or blurred vision
  • Fatigue or coordination problems
  • More serious side effects may include severe skin reactions, low sodium levels, or mood changes

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