Lioresal® (Baclofen) Oral Tablets for Muscle Spasms

What Baclofen Is and How It Works

Baclofen is a prescription muscle relaxant used to treat muscle spasms and chronic spasticity from conditions like multiple sclerosis or spinal cord injury. It works on GABA-B receptors in the spinal cord to reduce reflexes that cause tightness, cramps, and pain. People often look at buying baclofen online to access Canadian pricing and steady supply. Many compare baclofen cost without insurance to lower their monthly spend.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba. Prescriptions are reviewed by licensed pharmacists before dispensing, and we offer Canadian prices on brand and generic medicines with customer support during posted hours.

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This baclofen medication is typically supplied as a baclofen 10 mg tablet or a 20 mg tablet, taken by mouth several times daily. The baclofen pill helps relax skeletal muscles and ease painful spasms. Common baclofen uses include improving mobility and sleep when spasms interfere with daily function. For clarity, Lioresal is a brand name; baclofen is the active ingredient.

Dosage and Usage

• Typical starting dose: 5 mg three times daily.
• Titrate by increasing each dose by 5 mg every 3 days as tolerated.
• Usual effective total daily dose: 40–80 mg in divided doses.
• Maximum recommended: 80 mg per day (for example, 20 mg four times daily).
• Take with or without food; try food or milk if nausea occurs.
• Swallow tablets with water. Do not crush unless your pharmacist confirms it is safe for your specific product.
• A baclofen tablet 10 mg is common for initiation and stepwise titration.
• If you miss a dose, take it when remembered unless it is close to your next dose. Do not double doses.
• Do not stop suddenly. Taper gradually, typically reducing by 5–10 mg every 3 days, as directed by your prescriber.

Ask your prescriber about the right schedule for your condition. Baclofen dosage forms include 10 mg and 20 mg tablets; an oral solution may be available in some markets.

• Store tablets at 20–25°C (68–77°F). Brief excursions between 15–30°C (59–86°F) are acceptable.
• Keep the bottle tightly closed and protect from moisture.
• Do not store in the bathroom. Avoid excessive heat and direct sunlight.
• When traveling, keep tablets in the original labeled bottle in your carry-on.
• No refrigeration is required. Keep out of reach of children and pets.

Benefits and Savings

Baclofen helps reduce muscle spasms, stiffness, and clonus. Many patients report less pain and better mobility. Sleep quality may improve when night spasms decrease. Tablet dosing is straightforward and can be adjusted in small steps. Generic baclofen is widely available and often more affordable than branded options.

Ordering through a Canadian pharmacy can mean 60–80% savings compared with typical US prices. We list baclofen price options by strength and quantity, and multi-month supplies can lower the per-month baclofen cost. Patients comparing cost of baclofen without insurance often find the generic offers strong value for long-term therapy.

For current deals, see our baclofen coupon page.

Side Effects and Safety

• Drowsiness or fatigue
• Dizziness or lightheadedness
• Weakness
• Nausea or upset stomach
• Headache
• Dry mouth
• Constipation
• Insomnia

Serious effects are uncommon but can include confusion, hallucinations, breathing difficulty, very low muscle tone, or seizures. Abrupt discontinuation can cause agitation, rebound spasticity, hallucinations, or seizures. Taper baclofen slowly under medical guidance. Avoid alcohol and use caution with opioids, benzodiazepines, sedating antihistamines, and other CNS depressants. Dose adjustments may be needed in kidney impairment. Discuss risks if pregnant or breastfeeding.

Onset Time

Some muscle relaxation may appear within a few days of starting baclofen or after a dose increase. Spasm reduction often builds over 1–2 weeks as the dose is titrated. Sleep and pain improvements may follow as spasms lessen. If benefits are limited at a given dose, prescribers often adjust in small steps to balance relief and tolerability.

Compare With Alternatives

Tizanidine is another antispastic agent. It can be effective for spasticity but may cause more low blood pressure and dry mouth. It is often dosed at night due to sedation.

Cyclobenzaprine is useful for acute musculoskeletal spasms, such as neck or back strain, but it is less suited for chronic neurologic spasticity. It can be more sedating and has anticholinergic effects, which may not suit older adults.

Diazepam can relax muscles and ease spasms but carries higher risks of dependence, excessive sedation, and cognitive effects, so it is usually not a first choice for long-term control.

Combination Therapy

• With acetaminophen or an NSAID to address pain linked to spasms.
• With physical therapy and stretching to improve range of motion and function.
• With neuropathic pain agents (for example, gabapentin) when nerve pain coexists; monitor for added drowsiness.
• Avoid or use extreme caution with opioids or benzodiazepines; use the lowest effective doses if prescribed together.
• Limit alcohol and other sedatives to reduce dizziness, falls, and impaired alertness.

Patient Suitability and Cost-Saving Tips

Baclofen is used for chronic spasticity and troublesome muscle spasms. It may not be appropriate for people with severe kidney disease unless dosing is adjusted. Use caution if you have a history of seizures, mood disorders, or confusion. Older adults may be more sensitive to drowsiness and dizziness. Avoid activities requiring alertness until you know how this baclofen drug affects you. Discuss use during pregnancy or breastfeeding with your clinician.

To reduce costs, consider a 90-day supply if your prescriber agrees. Bulk promotions can lower the per-month baclofen 10 mg price. Enable reorder reminders so you do not run short. Compare strengths and pack sizes to find the best baclofen price per tablet. Many patients evaluate baclofen cost without insurance and choose the generically priced baclofen 10 mg uses that fit their therapy plan.

Authoritative Sources

FDA Prescribing Information for Lioresal (baclofen) tablets

Health Canada Drug Product Database: Baclofen

Order Lioresal® from Youdrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This content is educational and not a substitute for professional medical advice. Always consult your healthcare provider about diagnosis, treatment, and dosing.