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Benadryl Total

Benadryl Total® Caplets for Allergies and Sinus Congestion

Allergic Rhinitis (Hay Fever), Hives (Urticaria), Insomnia

Please note: a valid prescription is required for all prescription medication.

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Benadryl Total is an antihistamine and decongestant for allergy and sinus symptoms. It helps relieve sneezing, runny nose, itchy eyes, and nasal pressure. Available with US shipping from Canada, many choose Benadryl Total without insurance.

What Benadryl Total Is and How It Works

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Benadryl Total® Allergy & Sinus combines diphenhydramine, a first-generation antihistamine, with a nasal decongestant. The antihistamine blocks histamine at H1 receptors, which may ease sneezing, itching, watery eyes, and runny nose. The decongestant reduces swelling in nasal passages, which can improve airflow and reduce pressure. This medicine is used for seasonal triggers, indoor allergens, and common colds. Effects can include drowsiness, so plan activities accordingly and avoid alcohol.

For ongoing hay fever education, see our guide to Allergic Rhinitis.

Who It’s For

This treatment is intended for adults and adolescents when an antihistamine and a decongestant are both needed. It may help those with sneezing, runny nose, itchy or watery eyes, and sinus congestion. People with chronic hives may also benefit from short-term use during flares; learn more about the condition here: Hives Urticaria.

Avoid use if you have severe high blood pressure, severe heart disease, narrow-angle glaucoma, trouble urinating due to enlarged prostate, or if you take or recently took an MAOI. Do not use in children under 12 unless a healthcare professional advises it. Discuss use during pregnancy or breastfeeding with a clinician. If you are sensitive to sedating antihistamines, choose a non-drowsy option.

Antihistamine allergy relief tablets

Dosage and Usage

Follow the package directions. Adults and adolescents 12 years and older typically take a dose every 4 to 6 hours as needed. Swallow caplets whole with water. Use the lowest effective dose for the shortest time needed. Do not exceed the maximum daily dose on the label. Avoid combining with other products that contain antihistamines or decongestants. If you also take pain relievers or cough medicines, check active ingredients to prevent duplication.

Allergy and sinus relief caplets

Tips for use:

  • Take with a small snack if stomach upset occurs.
  • Avoid alcohol or cannabis; added sedation can occur.
  • Use caution with driving or machinery until you know your response.
  • For nighttime symptoms, plan dosing so drowsiness aligns with bedtime.

For broader product options, explore our Allergies category.

Strengths and Forms

Common presentations include caplets formulated for multi-symptom relief. In Canada, published strengths often combine diphenhydramine HCl 25 mg with phenylephrine HCl 5 mg; some extra-strength formats use higher amounts. Availability can vary by pack and region.

Diphenhydramine 25 mg caplets

You may also see count options suited for short trips or longer stretches. If you prefer single-ingredient options, consider Diphenhydramine or the higher-strength variant Diphenhydramine Xst, as advised by a healthcare professional.

Missed Dose and Timing

This product is often taken as needed. If you use a regular schedule, take a missed dose when remembered unless it is close to the next. Do not double up to make up a dose. For short-term congestion, do not use for longer than directed on the label without asking a prescriber.

Storage and Travel Basics

Store at room temperature in a dry place, away from direct heat and light. Keep the bottle or blister pack closed and out of children’s reach. Do not use tablets that are chipped or show unusual color or odor. For travel, keep the original packaging in your carry-on. A simple medication list can speed security checks. If you cross time zones, maintain spacing between doses based on hours between doses rather than clock times.

Because drowsiness may occur, consider taking doses when you are not planning complex tasks. If nighttime symptoms are prominent, you can time doses so that sedating effects occur closer to bedtime.

Benefits

This combination can relieve several symptoms at once, which may reduce the need for multiple products. Many people find the caplet format straightforward and portable. The treatment can be helpful for seasonal peaks, travel exposure to new allergens, or when a cold triggers persistent nasal congestion and itch. Non-drowsy alternatives exist if daytime alertness is essential.

For practical lifestyle pointers, see Beat Your Allergies.

Side Effects and Safety

  • Common: drowsiness, dry mouth or nose, dizziness, blurred vision
  • Digestive: nausea, constipation, decreased appetite
  • Restlessness: irritability or trouble sleeping in some people
  • Cardiovascular: increased heart rate or blood pressure sensitivity

Serious effects are uncommon but can include confusion, severe drowsiness, allergic reactions, trouble urinating, or vision changes. Seek urgent care for chest pain, severe headache, fainting, or swelling of face or throat. The risk of low blood sugar applies to insulin or sulfonylurea medicines; this product does not treat diabetes, but sedation may mask symptoms—use caution if you have conditions where alertness is critical.

Drug Interactions and Cautions

Avoid using with MAOIs or within 14 days of stopping one. Use caution with other sedatives, sleep aids, anxiolytics, opioids, or alcohol. Check labels on cold or allergy products to prevent duplicate antihistamines or decongestants. People with asthma, COPD, thyroid disease, diabetes, glaucoma, or urinary retention should consult a healthcare professional before use. If you take blood pressure medicines or antidepressants, ask your clinician about suitability.

What to Expect Over Time

Symptoms like sneezing, runny nose, and itch may improve after the first doses. Nasal relief may be more noticeable once swelling in the passages decreases. Sedation can occur, especially with the first doses. If daytime drowsiness is a concern, consider using a non-sedating antihistamine for the day and reserving a sedating option for the evening after discussing with your prescriber. For seasonal patterns, start when exposures begin and reassess after several days. Read our overview of Seasonal Allergies for practical tips.

Compare With Alternatives

Non-drowsy antihistamines are common choices for daytime control. Loratadine is one option; see Claritin Kids for a pediatric format your prescriber may recommend. For persistent nasal blockage, an intranasal steroid can help reduce inflammation; see Omnaris Nasal Spray. Each option has different pros, such as lower sedation or targeted nasal action.

Pricing and Access

We offer Canadian options with direct US fulfilment. Review Benadryl Total Canadian pricing on the product page, then compare packs to suit your needs. Add to cart to see current pricing and taxes. If you pay cash, our checkout supports secure card processing with encrypted checkout. For multi-symptom colds that include chest congestion, you might also review Mucinex Cold Sinus.

Ships from Canada to US is available for this item. Looking for a current deal? Check our Promotions page.

Availability and Substitutions

Stock can vary by pack size and format. If your selection is unavailable, a prescriber or pharmacist may suggest a suitable alternative, such as a non-drowsy antihistamine or a separate decongestant. Benadryl Total 48 caplets

Patient Suitability and Cost-Saving Tips

This medicine may suit adults who need both antihistamine and decongestant effects. It may not suit those with uncontrolled hypertension, significant heart disease, glaucoma, or urinary retention. Consider non-drowsy options for daytime use if alertness is crucial. For value, consider multi-month orders when appropriate, and set refill reminders so you do not run out during peak seasons. You can also compare single-ingredient antihistamines, which may cost less when congestion is brief. If sleep disruption is a concern, review our Insomnia resource and speak with your clinician.

Questions to Ask Your Clinician

  • Is a sedating antihistamine appropriate for my daytime routine?
  • Should I use a nasal steroid or saline with this product?
  • What signs suggest I should stop and seek medical advice?
  • How long can I use a decongestant safely?
  • Could a non-drowsy antihistamine be better for me?

Authoritative Sources

Benadryl Canada

DailyMed

Health Canada DPD

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