Braftovi® Capsules for BRAF-Mutant Melanoma

Braftovi® is an oral kinase inhibitor used with partner therapies for certain BRAF‑mutant cancers. This page explains uses, safety, and ways to access treatment, with US delivery from Canada. If you pay without insurance, you can review options and discuss affordability with your prescriber.

What Braftovi Is and How It Works

Braftovi contains encorafenib, a selective inhibitor of mutated BRAF V600 kinases. It helps block abnormal signaling that drives tumor growth in specific cancers. It is used with other agents because dual pathway targeting can improve outcomes and manage resistance, per approved labeling.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

In melanoma and lung cancer, this medicine is paired with a MEK inhibitor. In colorectal cancer, it is paired with an EGFR antibody. It should not be used in patients with wild‑type BRAF tumors. Your healthcare professional will confirm mutation status before starting therapy and will monitor for known risks such as ocular effects, liver changes, and skin findings.

For access questions, some patients search for Encorafenib from Canada. Speak with your clinician and our team about appropriate options.

Who It’s For

This treatment is indicated for adults with:

• Unresectable or metastatic melanoma with BRAF V600E or V600K mutation, used with a MEK inhibitor.
• Metastatic colorectal cancer with BRAF V600E mutation, used with an EGFR inhibitor.
• Metastatic non‑small cell lung cancer with BRAF V600E mutation, used with a MEK inhibitor.

It is not for cancers without a BRAF V600 mutation. Tell your prescriber about heart conditions, liver problems, eye issues, bleeding risks, and all medicines you take. Pregnancy should be avoided; effective contraception is recommended during therapy and for a period after the last dose, per labeling.

For cancer education, see Common Types Of Cancer and Immunotherapy For Cancer. Condition pages such as Melanoma and Colorectal Cancer may also help.

Dosage and Usage

Dosing varies by indication and the partner medicine. It is typically taken by mouth once daily. Swallow capsules whole with water. Take with or without food. Do not crush or open capsules.

If vomiting occurs after a dose, do not take an extra dose. Resume the regular schedule. Avoid grapefruit and grapefruit juice because they may affect levels. Your prescriber may adjust therapy for side effects. Follow the Patient Information and the Prescribing Information for full directions.

Strengths and Forms

Capsules are commonly supplied in these strengths:

• 50 mg capsules
• 75 mg capsules

Availability can vary by supply and manufacturer packaging.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember unless the next dose is due soon. If it is close to the next scheduled time, skip the missed dose and take the next dose as usual. Do not take two doses at once to make up for a missed dose. Check the Medication Guide for timing details, as instructions may vary by indication and partner drug.

Storage and Travel Basics

Store capsules at room temperature in the original bottle, tightly closed, with the desiccant inside. Keep away from moisture and direct light. Do not transfer to a pill organizer unless your clinician approves. Keep out of reach of children and pets.

When traveling, keep the bottle in your carry‑on. Bring a copy of your prescription and a medication list. Use a reminder system to maintain steady dosing. If you cross time zones, ask your healthcare professional how to adjust your schedule. Our site uses encrypted checkout for your privacy.

Pen Handling and Sharps Disposal

This medicine is supplied as capsules. No pen devices or sharps are involved, so sharps disposal is not required.

Benefits

This targeted therapy works on the BRAF pathway that drives certain tumors. It is taken orally and is used with a partner medicine selected by your prescriber. Combination regimens can help manage resistance pathways. The capsule format can be convenient for home use when appropriate monitoring is in place.

Side Effects and Safety

• Common: fatigue, nausea, vomiting, diarrhea, abdominal discomfort
• Skin: rash, dryness, photosensitivity, new skin lesions
• Muscle and joint: pain or stiffness
• Eye: blurred vision, visual changes
• Lab changes: liver enzyme elevations, creatine kinase increases
• Cardiac: feelings of palpitations

Serious risks can include new primary malignancies, bleeding, uveitis or retinal problems, liver injury, QT prolongation, and heart effects when combined with certain partners. Get urgent help for severe headache, sudden vision changes, fainting, significant bleeding, shortness of breath, or severe rash. Your prescriber may order regular skin checks, eye exams, EKGs, and blood tests.

Drug Interactions and Cautions

Encorafenib is metabolized by CYP3A4. Strong CYP3A inhibitors can raise levels, and strong inducers can lower them. Avoid grapefruit. Use caution with medicines that prolong the QT interval and with agents that increase bleeding risk. Tell your prescriber about all prescription drugs, OTC products, vitamins, and herbal supplements you use.

Limit sun exposure and use protective clothing and sunscreen. Report visual symptoms promptly. Do not start, stop, or change any therapy without guidance from your healthcare professional.

What to Expect Over Time

Your care team will monitor how you respond and how you tolerate treatment. Skin and GI effects may appear early and are often manageable with supportive care and adjustments directed by your prescriber. Regular lab work and eye checks help track safety. Keep a simple log of doses and any symptoms, and bring it to visits. Staying consistent with daily dosing can support your treatment plan.

Compare With Alternatives

Other pathway‑targeting regimens may be considered based on tumor type and mutations. For BRAF‑mutant melanoma, a MEK inhibitor such as Mekinist may be used in combination regimens chosen by your specialist. For previously treated metastatic colorectal cancer, multikinase therapy like Stivarga may be an option in select settings. Discuss how these compare to your plan, including a Braftovi price comparison, with your oncology team.

Pricing and Access

We provide transparent information so you can review Encorafenib capsules price with your prescriber and plan refills appropriately.

Our team lists current Canadian options and helps you understand Braftovi Canadian pricing for available packs. We do not post dollar amounts here because supply can change.

You can request a quote, upload your prescription, and ask about typical savings for those paying cash. Many patients explore costs without insurance and compare options across pack sizes. US fulfillment uses licensed channels, and orders Ships from Canada to US. See our Cancer category for related therapies.

Availability and Substitutions

Supply can vary by strength and pack size. If a specific bottle is unavailable, your prescriber may recommend an alternative regimen or a different quantity to match your schedule. Talk with our pharmacists if you have questions about Encorafenib price and timing. If substitution is considered, your clinician will decide whether a change fits your treatment goals.

Patient Suitability and Cost-Saving Tips

Good candidates have a confirmed BRAF V600 mutation and can participate in regular monitoring. This therapy may not suit those with certain eye conditions, significant liver impairment, or poorly controlled cardiac issues. Your prescriber weighs risks and benefits with your history and other medicines.

Cost‑saving ideas:

• Multi‑month fills: reduce per‑fill fees and help adherence.
• Aligned refills: coordinate partner drugs for fewer shipments.
• Early reorders: avoid gaps; set gentle reminders in your calendar.
• Discuss Encorafenib cost with your prescriber to choose practical pack sizes.
• Ask about manufacturer resources or clinical guidance that may help planning.

Questions to Ask Your Clinician

• Is my tumor confirmed BRAF V600‑mutant, and which partner medicine fits?
• What monitoring do I need for eyes, skin, heart, and liver?
• How should I manage sun exposure, rash, or GI symptoms at home?
• Which medicines or supplements should I avoid during therapy?
• What signs mean I should contact the clinic right away?
• How will we review goals if treatment needs to change?

Authoritative Sources

FDA Prescribing InformationHealth Canada DPDManufacturer Site

Ready to proceed? You can place your request with US shipping from Canada and prompt service, with temperature-controlled handling when required. This information is not a substitute for the advice of your healthcare professional.