Dostinex® (Cabergoline) Uses, Dosing, and Safety Information

What Dostinex® Is and How It Works

Cabergoline is a dopamine D2 receptor agonist used to lower prolactin. It treats hyperprolactinemia, including prolactin-secreting pituitary adenomas (prolactinomas). It helps normalize prolactin and may shrink tumor size. Many people compare Cabergoline price and cabergoline cost when considering cabergoline online from a licensed source.

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Cabergoline comes mainly as 0.5 mg tablets, sometimes scored. Dosing is usually twice weekly. The medicine works by stimulating dopamine receptors on pituitary lactotroph cells. This suppresses prolactin release. Lower prolactin levels can restore ovulation and resolve symptoms like galactorrhea and menstrual changes. In prolactinoma, reduced prolactin can correlate with tumor shrinkage on imaging.

Common reasons to prescribe include cabergoline for hyperprolactinemia, cabergoline for high prolactin, and cabergoline prolactinoma management. Some clinicians use it to suppress lactation when medically necessary. Use for stopping breast milk depends on local guidance and the individual case. Cabergoline pills should be taken exactly as directed by the prescriber.

Dosage and Usage

• Initiation: many adults start at 0.25 mg twice weekly.
• Titration: increase by 0.25 mg per week every 4 weeks if needed.
• Typical maintenance: 0.5–1 mg per week in divided doses.
• Maximum doses vary; some patients require up to 2 mg weekly.
• Take with food if nausea occurs; timing is flexible but consistent schedules help.
• Missed dose: take when remembered if far from the next dose; otherwise skip.
• Do not double doses to make up for a missed dose.
• If therapy pauses, prolactin may rise again; clinicians reassess dosing.
• Periodic monitoring of prolactin levels guides adjustments.
• Imaging may be used to track prolactinoma size changes.

• Store tablets at 15–30 °C (59–86 °F), away from moisture.
• Keep tablets in the original bottle with the desiccant.
• Do not store in a bathroom or near a sink.
• For travel, keep tablets in your carry-on with labels attached.
• Avoid heat exposure in cars or direct sun.
• Do not freeze or refrigerate; keep dry and tightly closed.
• Use a pill organizer only if kept dry and cool.
• Pack extra doses for trips in case of delays.

Benefits and Savings

Cabergoline has a long half-life and convenient twice-weekly schedule. It often normalizes prolactin more reliably than some alternatives. Many people see improved menstrual regularity and fertility when prolactin normalizes. In prolactinoma, cabergoline can reduce tumor size over time. Tablets are small and easy to take, which supports adherence.

Buying cabergoline through YouDrugstore offers access to Canadian pricing. Typical savings versus US retail can reach 60–80% depending on strength and supply. If you compare cabergoline for sale across pharmacies, review total costs, including shipping and pharmacist review. Multi-month supplies can lower the per-month cost, and periodic promotions may improve the overall cabergoline discount.

For current offers, see our cabergoline coupon page. We work with licensed, vetted international partner pharmacies to provide authentic brand medications across a broad selection at affordable prices.

Searches like cabergoline tablets online, cabergoline dose details, and cabergoline uses are common. Strength availability can vary by market. Many listings focus on 0.5 mg tablets, and some regions carry other strengths. Check current options and cabergoline 0.5 price on the product page. Where available, a cabergoline 1mg price may differ by manufacturer.

Side Effects and Safety

• Nausea, stomach upset, or constipation
• Dizziness or lightheadedness, especially when standing
• Headache or fatigue
• Nasal congestion
• Sleepiness or insomnia
• Breast discomfort changes as prolactin normalizes
• Leg or muscle cramps

Serious but less common risks include heart valve changes (valvulopathy), pulmonary or retroperitoneal fibrosis, and impulse-control symptoms. Risk increases with higher cumulative doses and long-term use. Those with structural heart valve disease or uncontrolled hypertension may not be candidates. Drug interactions can occur with dopamine antagonists (for example, some antipsychotics or metoclopramide) and strong CYP3A4 inhibitors. Alcohol or antihypertensives may increase dizziness.

Onset Time

Prolactin often begins to drop within days of the first dose. Many people see symptomatic changes, such as reduced galactorrhea or improved cycle regularity, within several weeks. For prolactinomas, tumor shrinkage can take weeks to months and is usually assessed on follow-up imaging. Dose adjustments are made gradually to balance efficacy and tolerability.

Compare With Alternatives

Bromocriptine is another dopamine agonist used for hyperprolactinemia. It is typically dosed daily and may cause more nausea in some patients. Cabergoline’s twice-weekly dosing can be easier to maintain, and many studies show stronger prolactin suppression.

Quinagolide is a non-ergot dopamine agonist available in some regions. It is taken daily. Some tolerate it well, but availability differs by country. Where it is not available, cabergoline or bromocriptine are the usual options.

Transsphenoidal surgery is considered in selected prolactinoma cases, especially when medication is not effective or tolerated, or if visual symptoms persist. Radiation therapy is reserved for resistant tumors. Medical therapy with cabergoline remains a first-line approach for many.

Combination Therapy

• With oral contraceptives: used to regulate cycles after prolactin normalization as advised by a clinician.
• With fertility treatments: dosing may continue while specialists manage ovulation induction.
• With levothyroxine: address concurrent hypothyroidism contributing to elevated prolactin.
• With antipsychotics: coordination is important, as some agents raise prolactin and blunt response.
• With antihypertensives: monitor for additive dizziness or low blood pressure.

Patient Suitability and Cost-Saving Tips

Cabergoline is used for people with elevated prolactin due to pituitary adenoma or idiopathic hyperprolactinemia. It may be used to suppress lactation when medically necessary. Those with moderate to severe valvular heart disease, pulmonary or retroperitoneal fibrosis, or uncontrolled hypertension may not be suitable. A careful review of cardiac status is standard before long-term therapy.

Discuss plans for pregnancy with a healthcare professional. Prolactin normalization can restore fertility, which may require contraceptive planning if pregnancy is not desired. Those on interacting medications, such as dopamine antagonists, may need adjustments or alternative strategies.

To manage cabergoline cost, consider a longer supply. Bulk promotions can reduce the per-month expense. Reorder reminders help prevent gaps in therapy. Check current cabergoline for sale listings and compare total costs from reputable pharmacies. Pricing can vary by brand and strength; people often compare cabergoline 0.5 price and cabergoline 1mg price where both are available.

Cabergoline medication is prescription-only and not available over the counter in most regions. If you are buying cabergoline or searching cabergoline tablets online, confirm that a valid prescription is required and reviewed. Dose and duration are individualized based on prolactin levels and clinical response.

Authoritative Sources

Pfizer product page for Dostinex (cabergoline)

U.S. FDA application and prescribing information for Dostinex

Health Canada Drug Product Database (search cabergoline)

Order Dostinex® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express shipping.

This content is educational and does not replace advice from your healthcare professional. Always follow the guidance of your prescriber and pharmacist.