Caduet® Tablets for Blood Pressure and Cholesterol Control

What Caduet® Is and How It Works

Caduet® is a prescription tablet from Pfizer that combines two medicines: amlodipine and atorvastatin. It treats high blood pressure or angina while lowering LDL cholesterol and triglycerides. If you compare Caduet 5 10 price options, you can often reduce total therapy costs, even for those buying caduet without insurance.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and our pharmacists review each prescription before dispensing. We also partner with licensed, vetted international pharmacies to source authentic brand medicines across many categories at affordable prices.

Amlodipine is a calcium channel blocker. It relaxes blood vessels to reduce blood pressure and chest pain. Atorvastatin is an HMG‑CoA reductase inhibitor (statin). It lowers cholesterol by reducing hepatic synthesis and increasing LDL clearance. Together, they address two major cardiovascular risks with one daily tablet.

Caduet® is taken by mouth once daily, with or without food. Tablet strengths combine the two components in fixed doses, such as 5/10 mg, 5/20 mg, 5/40 mg, 10/10 mg, 10/20 mg, and 10/40 mg. The generic name is amlodipine/atorvastatin. Some patients start at lower doses and titrate after assessment.

By targeting both blood pressure and lipids, Caduet® can simplify therapy and improve adherence. Your clinician selects a strength that matches your blood pressure and cholesterol goals and your tolerance.

Dosage and Usage

• Take one Caduet® tablet once daily at the same time each day.
• Swallow whole with water. Take with or without food.
• Common starting strengths include 5/10 mg or 10/10 mg. Your dose may increase after 2–4 weeks based on response.
• If you are switching from separate amlodipine and atorvastatin tablets, your prescriber may match the nearest fixed-dose combination.
• Missed dose: take it when remembered the same day. If it is near the next dose, skip the missed dose. Do not double doses.
• Avoid grapefruit or grapefruit juice with atorvastatin due to interaction risk.
• Report unexplained muscle pain, weakness, or dark urine promptly.
• Tell your prescriber about all medicines, including macrolide antibiotics, azole antifungals, protease inhibitors, cyclosporine, or fibrates.

Storage and Travel

• Store at 20–25 °C (68–77 °F); short excursions 15–30 °C (59–86 °F) are acceptable.
• Keep tablets in the original container, tightly closed, and protect from moisture and light.
• Do not store in a bathroom. Keep out of reach of children and pets.
• When traveling, carry your medication in your hand luggage with a copy of your prescription.
• Use a pill organizer to help maintain your daily schedule. Bring extra tablets for delays.

Benefits and Savings

Caduet® treats two conditions with one daily dose. This can reduce pill burden and simplify refills. Amlodipine helps lower blood pressure and can reduce angina symptoms. Atorvastatin lowers LDL cholesterol, supports plaque stabilization, and reduces cardiovascular risk over time.

Buying from Canada often means meaningful savings. Many customers see 60–80% lower costs versus typical U.S. retail pricing. If you are comparing caduet cost across strengths like 5/20 mg or 10/20 mg, multi‑month supplies can lower your per‑month expense. Savings can be significant for those paying caduet without insurance.

For extra savings opportunities, see our caduet coupon page.

Side Effects and Safety

• Common: swelling of ankles or feet (edema), flushing, dizziness, headache.
• Gastrointestinal: nausea, diarrhea, abdominal discomfort, constipation, dyspepsia.
• Musculoskeletal: muscle aches, joint pain, back pain.
• Laboratory: increases in liver enzymes or creatine kinase.
• General: fatigue, nasopharyngitis.

Serious but uncommon events include myopathy or rhabdomyolysis (risk increases with interacting drugs), severe liver injury, or symptomatic hypotension. Avoid use in pregnancy and while breastfeeding. Do not use with active liver disease or unexplained persistent transaminase elevations. Limit alcohol. Discuss grapefruit products, strong CYP3A4 inhibitors, and fibrates with your prescriber.

Onset Time

Blood pressure improvements from the amlodipine component often begin within days, with most effect over 1–2 weeks as the dose stabilizes. Angina frequency may decline over this period. Lipid changes from atorvastatin appear within 2–4 weeks, with further gains by 6–8 weeks. Cardiovascular risk reduction accrues with sustained control over months.

Compare With Alternatives

Some people take amlodipine and atorvastatin as separate tablets. Separate dosing can offer fine‑tuned adjustments if you need different strengths for blood pressure and cholesterol. Caduet® improves convenience if a fixed dose matches your goals.

Another option is pairing amlodipine with a different statin, such as rosuvastatin, prescribed as two tablets. Rosuvastatin provides strong LDL reduction and fewer CYP3A4 interactions, but you will take two medicines instead of one.

For blood pressure, alternatives include ACE inhibitors or ARBs, sometimes combined with amlodipine when additional control is needed. For lipids, alternatives include higher‑intensity statins, ezetimibe, or PCSK9 inhibitors for selected patients. For more background on how this combination works, read our article Caduet® Medication Managing Blood Pressure And Cholesterol.

Combination Therapy

• Caduet® plus an ACE inhibitor or ARB if blood pressure needs further reduction.
• Caduet® plus a thiazide diuretic for additive antihypertensive control.
• Caduet® plus ezetimibe for additional LDL‑C lowering when statin alone is insufficient.
• Avoid combining with gemfibrozil; if a fibrate is needed, prescribers often prefer fenofibrate with close monitoring.
• If adverse effects appear after changes, your prescriber may adjust one or both components.

Patient Suitability and Cost-Saving Tips

Caduet® may suit adults with both hypertension/angina and high LDL cholesterol who prefer once‑daily simplicity. It may not suit those with pregnancy plans, active liver disease, heavy alcohol use, or a history of statin‑related rhabdomyolysis. Use caution with severe aortic stenosis or in those prone to symptomatic hypotension.

Kidney function usually does not require dose adjustment for amlodipine or atorvastatin, but liver impairment may. Older adults can use Caduet® with careful titration. Tell your clinician about all medicines and supplements. Report muscle symptoms, persistent fatigue, jaundice, or severe dizziness promptly.

To reduce your caduet price, ask about generic amlodipine/atorvastatin where appropriate. You can order larger quantities when permitted; multi‑month supplies and bulk promotions can lower average monthly cost. Set simple reorder reminders so you do not run out. These steps help control your caduet cash price, especially if you pay caduet no insurance.

Authoritative Sources

Pfizer Caduet product information

Health Canada Drug Product Database listing

U.S. FDA prescribing information

Order Caduet® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This page is educational and does not replace advice from your healthcare professional. Always follow your prescriber’s directions for your own care.