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Mefoxin® Injection for Bacterial Infections
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Cefoxitin for Injection is a prescription antibiotic used in hospitals and clinics. It treats a range of susceptible bacterial infections and is given by trained staff. You can access Canadian pricing with US delivery from Canada, which may help if you pay without insurance.
What Mefoxin Is and How It Works
Mefoxin® contains cefoxitin, a cephamycin beta-lactam that inhibits bacterial cell wall synthesis. This action weakens the wall and can kill susceptible organisms. As a parenteral product, cefoxitin sodium injection is used for moderate to severe infections or for perioperative prophylaxis where appropriate. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This medicine covers many Gram-negative and Gram-positive bacteria, including some anaerobes such as Bacteroides fragilis. Activity may vary by local resistance patterns. Cultures and sensitivity testing can guide therapy. It does not treat viral illnesses like colds or flu.
Who It’s For
This treatment is indicated for adults and children when bacteria are likely to be susceptible. Labeled uses include lower respiratory tract, urinary tract, skin and skin-structure, bone and joint, gynecologic, and intra-abdominal infections. It may also be used for surgical prophylaxis in contaminated or clean-contaminated gastrointestinal and gynecologic procedures, per the official label.
People with a known serious allergy to cephalosporins should not receive this medicine. Those with a history of severe immediate hypersensitivity to penicillins may also require caution due to possible cross-reactivity. Discuss kidney function, prior colitis, and any anticoagulant use with your prescriber before starting therapy.
Dosage and Usage
Dosing and duration are set by your clinician based on the site and severity of infection, patient age, and kidney function. In hospitals, the drug is given intravenously or intramuscularly at intervals typically every 6 to 8 hours. For surgical prophylaxis, a pre-incision dose is commonly used, with possible intraoperative and postoperative doses depending on procedure length and contamination risk. Do not adjust or stop therapy unless your prescriber instructs you to do so. As a hospital product, cefoxitin IV injection is prepared and administered by healthcare professionals.
Complete the prescribed course even if you start to feel better. Early discontinuation can allow infection to return. If cultures and susceptibility results become available, the regimen may be narrowed or revised by the care team.
Strengths and Forms
This product is supplied as a sterile powder to be reconstituted for IV or IM use. Availability may vary by supplier and market.
- cefoxitin 1 g vial single-use powder for reconstitution
- 2 g vial single-use powder for reconstitution
Hospitals follow label instructions for reconstitution and compatible diluents. Pharmacy staff or nurses prepare doses under aseptic conditions.
Missed Dose and Timing
This medicine is generally scheduled and administered by clinical staff. If a dose is delayed, the team will adjust timing to maintain appropriate intervals. For outpatient parenteral therapy, contact your prescriber or infusion service if you miss an appointment. Do not double the next dose.
Storage and Travel Basics
Unreconstituted vials are typically stored at controlled room temperature in the original carton, protected from moisture. After reconstitution or dilution, stability depends on diluent and temperature; hospitals refer to the official label and institutional policies for beyond-use times. Do not use solutions that are discolored or contain particulate matter.
Keep all medicines out of reach of children. If you must transport vials, keep them in the original packaging with a copy of your prescription or infusion plan. Avoid excessive heat or freezing. For prepared solutions, follow the infusion provider’s instructions regarding refrigeration or time at room temperature.
For more on related conditions, see Intra Abdominal Infection, Urinary Tract Infection, and Skin And Soft Tissue Infection.
Benefits
This cephamycin can provide broad coverage for mixed aerobic and anaerobic infections, including many intra-abdominal and gynecologic cases. It is useful for hospital-acquired settings where IV therapy is preferred. Perioperative dosing can reduce the risk of postoperative infectious complications when used according to surgical prophylaxis guidelines.
As a parenteral option, it allows reliable tissue levels in serious infections. Pharmacy-prepared doses support consistent administration. When cultures guide therapy, the regimen can be optimized to limit unnecessary exposure.
Side Effects and Safety
- Gastrointestinal: nausea, vomiting, diarrhea
- Injection site: pain, redness, swelling
- Skin: rash, itching
- Lab effects: transient liver enzyme elevations
- Hematologic: eosinophilia, positive Coombs test
Serious reactions can include severe hypersensitivity, Clostridioides difficile–associated diarrhea, seizures (especially with renal impairment), or rare hematologic changes. Seek urgent care for breathing difficulty, widespread rash, severe diarrhea, or unusual bleeding. Report any new symptoms to your healthcare professional promptly.
Drug Interactions and Cautions
Important interactions may include probenecid, which can increase cefoxitin levels by reducing renal tubular secretion. Concomitant aminoglycosides or potent diuretics may raise the risk of kidney effects; careful monitoring is advised. Broad-spectrum antibiotics can affect gut flora and may potentiate anticoagulant effects of warfarin-like agents; clinicians often monitor INR and adjust therapy as needed.
Inform your prescriber about prior beta-lactam reactions, kidney disease, or colitis. Sodium load from this product should be considered in patients on sodium-restricted diets. Cefoxitin may interfere with some lab tests, such as direct Coombs testing and urine glucose assays that use copper reduction methods.
For context on kidney considerations, read Liver And Kidney Disease. For urinary topics, see Bladder And Kidney Infections.
What to Expect Over Time
Symptoms may begin to improve after several doses as bacterial growth is controlled. Lab values and vital signs guide ongoing care. Your team may adjust therapy based on culture results or clinical response. Completing the full course helps reduce relapse and resistance. If side effects occur, notify your clinician so risks and benefits can be reassessed.
Compare With Alternatives
Depending on culture results and site of infection, clinicians may select other antibiotics. Fluoroquinolones are sometimes used for specific Gram-negative infections; see Ciprofloxacin Hcl. For anaerobic and mixed intra-abdominal infections, a nitroimidazole may be combined with other agents; see Metronidazole. Choice depends on susceptibility, patient factors, and guidelines.
Pricing and Access
Hospitals and clinics can review cefoxitin injection price by adding the vial size to your cart. Canadian suppliers often provide competitive rates with US shipping from Canada. If you need a general overview of savings opportunities, check our Promotions page. We also list category options for review under Infectious Disease.
Some buyers look for a cefoxitin injection coupon, while others compare cefoxitin vial price and cefoxitin cost per vial across suppliers. Add items to your cart to see current pricing and any available offers at checkout.
Availability and Substitutions
Supply may vary by manufacturer. If a specific vial size is unavailable, your prescriber may recommend an alternative agent with similar coverage or adjust the plan. You can order cefoxitin injection online once you have a valid prescription, and our team will coordinate with your provider if clarification is needed.
Patient Suitability and Cost-Saving Tips
Good candidates include patients with culture-supported infections where this agent is appropriate, or those needing perioperative prophylaxis consistent with guidelines. Those with severe beta-lactam allergies or significant renal impairment require careful evaluation. To manage costs, consider consolidating purchases for multiple wards or planned procedures, and use institutional reminders for timely reorders. Multi-vial orders may reduce administrative time for procurement teams.
If you self-pay, comparing cefoxitin injection US shipping options alongside cefoxitin injection from Canada can help with planning. Some buyers also review cefoxitin generic Mefoxin details before purchasing. Hospital buyers sometimes note Mefoxin injection alternatives or assess cefoxitin sodium 1 g and cefoxitin sodium 2 g availability depending on surgical schedules.
Questions to Ask Your Clinician
- Infection target: Which organisms are suspected or confirmed by culture?
- Therapy plan: What duration and route are expected for this course?
- Safety: What lab monitoring is recommended during treatment?
- Interactions: Do my current medicines affect bleeding or kidney risk?
- Prophylaxis: Is this the preferred agent for the planned procedure?
- De-escalation: When will culture results guide narrowing therapy?
Authoritative Sources
- Mefoxin (cefoxitin) US Prescribing Information
- DailyMed: Cefoxitin Listings
- Health Canada Drug Product Database
Availability Note and Checkout
Add your selected vial to the cart to view availability and lead times. Complete checkout for prompt fulfilment. We support encrypted checkout and standard record keeping for institutional orders.
Ready to proceed? Add to cart for quick review and payment, with prompt US fulfilment that Ships from Canada to US and temperature-controlled handling when required. This page is informational and does not replace advice from your healthcare professional.
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What infections does cefoxitin treat?
Cefoxitin is indicated for susceptible bacterial infections including lower respiratory tract, urinary tract, skin and skin-structure, bone and joint, gynecologic, and intra-abdominal infections. It is also used for surgical prophylaxis in contaminated or clean-contaminated gastrointestinal and gynecologic procedures. Your care team selects this option based on the likely organisms and local resistance patterns, and may adjust therapy after culture results are available.
How is cefoxitin given in the hospital?
This medicine is given by intravenous or intramuscular injection by trained staff. The dose and schedule depend on the site and severity of the infection, kidney function, and patient age. Intervals commonly range every 6 to 8 hours. For surgical prophylaxis, a pre-incision dose is often used, with further doses based on procedure length and contamination risk. Your clinician will follow label guidance and institutional protocols.
What are common side effects of cefoxitin?
Common effects include nausea, vomiting, diarrhea, rash, and injection site pain or swelling. Lab changes such as transient liver enzyme elevations or a positive Coombs test can occur. Serious reactions, though less common, include severe allergic responses, Clostridioides difficile–associated diarrhea, seizures in those with renal impairment, and rare blood disorders. Report concerning symptoms to your healthcare professional promptly.
Who should not receive cefoxitin?
Patients with a known serious hypersensitivity to cephalosporins should avoid it. Those with a history of immediate reactions to penicillins may be at higher risk of cross-reactivity and require caution. Kidney impairment, prior colitis, and sodium-restricted diets warrant additional review. Always share a full medication and allergy history with your prescriber before starting treatment.
Does cefoxitin interact with other medicines?
Probenecid can increase cefoxitin levels by reducing renal tubular secretion. Combined use with aminoglycosides or potent diuretics may raise kidney risk and needs monitoring. Broad-spectrum antibiotics can alter gut flora and affect warfarin-type anticoagulants, so clinicians often check INR during therapy. Cefoxitin may also interfere with certain lab tests, including the Coombs test and copper-reduction urine glucose assays.
How should cefoxitin vials be stored before use?
Unreconstituted vials are usually stored at controlled room temperature in the original carton and protected from moisture. Once reconstituted or diluted, stability depends on the chosen diluent and temperature; hospitals follow label directions for beyond-use times. Do not use solutions that appear cloudy or contain particles. Keep out of reach of children, and avoid extreme heat or freezing during any transport.
Can I buy this antibiotic for home use?
This product requires a prescription and professional administration. Outpatient use occurs through infusion services under clinician oversight. If you’re coordinating care, your prescriber will direct dosing and timing, and the pharmacy will supply vials for the planned course. Procurement teams can compare Canadian pricing and arrange institutional orders as needed through our checkout process.

