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Cosentyx® Injection for Plaque Psoriasis
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Cosentyx is a prescription biologic for plaque psoriasis and related conditions. This page explains what it treats, how to use it, and safety basics. You can request refills with US delivery from Canada, and review the Cosentyx cost without insurance.
What Cosentyx Is and How It Works
Cosentyx® contains secukinumab, a monoclonal antibody that targets interleukin‑17A (IL‑17A). By blocking IL‑17A, it helps calm overactive inflammation in skin and joints. The medication is supplied for self-injection as single-use devices, including the Cosentyx Sensoready Pen. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This treatment is approved for adults with moderate to severe plaque psoriasis. It is also indicated for psoriatic arthritis and axial spondyloarthritis, including ankylosing spondylitis and non‑radiographic disease. Pediatric plaque psoriasis use is approved for certain ages. For an overview of the skin condition it treats, see our guide to Plaque Psoriasis. You can also read community stories during World Psoriasis Day.
Who It’s For
This medicine may be suitable for adults with moderate to severe plaque psoriasis who need systemic therapy or phototherapy. It is also used for active psoriatic arthritis, with or without psoriasis, and for adults with axial spondyloarthritis. Some children with plaque psoriasis may also receive it when approved by their prescriber.
People with an active infection should not start this therapy. Those with chronic or recurrent infections, or a history of tuberculosis, need careful screening and monitoring. Individuals with inflammatory bowel disease may experience worsening symptoms and should discuss risks. People with known serious allergy to secukinumab or any component should not use it. Learn more about joint disease in our Psoriatic Arthritis and Ankylosing Spondylitis sections.
Dosage and Usage
Your prescriber will set your schedule based on your condition and response. Many patients begin with a weekly starter series followed by maintenance doses taken every month. For certain diagnoses, some people may use two injections on the same day of their maintenance schedule.
Prescribers sometimes choose Cosentyx 150 mg for individual needs. After a starting phase, ongoing use typically follows a regular monthly rhythm to help maintain control. Continue on the day assigned by your clinician to keep consistency. If many weeks pass between doses, your prescriber may reassess your plan.
Give injections subcutaneously in the thigh, abdomen, or back of the upper arm if someone else administers it. Rotate sites. Do not inject into areas that are tender, bruised, scaly, or infected. Inspect the solution. Do not use if the liquid is cloudy, discolored, or contains particles.
For broader context on medications used in joint disease, explore Arthritis Drugs. Advocacy resources during awareness months can also help with support and planning, such as Psoriasis Action Month.
Strengths and Forms
This product is supplied as single-use devices designed for at-home injection. Availability can vary by device type and quantity your prescriber selects.
- Prefilled syringe and autoinjector options for home use
- Typically provided as Cosentyx prefilled syringe or Sensoready pen
- Commonly published strength: 150 mg/mL
Not all presentations are always in stock. Device type may differ between first fill and refills depending on supply.
Missed Dose and Timing
If you miss a scheduled injection, take it as soon as you remember. Then take your next dose on the original day if possible. If the timing is unclear, contact your healthcare professional or see the official prescribing information. Avoid doubling doses to make up for a missed injection.
Storage and Travel Basics
Store in a refrigerator in the original carton to protect from light. Do not freeze. Do not shake. Before injecting, allow the device to reach room temperature out of the carton for the recommended warm-up time. If needed, limited time at room temperature is permitted per the official label; do not return it to the refrigerator once kept at room temperature.
For travel, keep the carton in insulated packaging with cold packs, avoiding direct contact with the device. Place the medicine in your carry-on. Bring your prescription label and a copy of your instructions from your prescriber in case security staff ask for documentation. Keep it out of reach of children and pets.
Pen Handling and Sharps Disposal
Let the pen or syringe warm up on a clean surface. Wash and dry your hands. Clean the injection site with an alcohol swab. With an autoinjector, place it flat against the skin and trigger as directed. Hold in place for the full time in your instructions. With a syringe, pinch the skin and inject at the angle taught by your clinician. Do not recap needles. Place used devices in an approved sharps container. Follow local rules for disposal; pharmacies can advise on disposal options.
Benefits
This therapy helps reduce plaque thickness, scaling, and redness. Many people experience less itch and improved comfort in difficult areas such as the scalp. Those with joint symptoms may notice reduced tenderness and stiffness. A monthly maintenance rhythm can be convenient once you have completed the starter phase. At-home injection also supports consistent use without frequent clinic visits.
Side Effects and Safety
- Upper respiratory infections, like a cold
- Headache or fatigue
- Diarrhea
- Nasal congestion or sore throat
- Injection-site redness or pain
Serious risks can include severe infections, reactivation of tuberculosis, and allergic reactions with swelling or hives. Inflammatory bowel disease may worsen in some people. Seek urgent care for signs of severe allergy or infection such as high fever, chills, or shortness of breath. Your prescriber may screen for tuberculosis before starting therapy.
Drug Interactions and Cautions
Avoid live vaccines while using this biologic. Tell your prescriber about all medicines you take, including immunosuppressants, corticosteroids, and biologics, as using multiple agents may raise infection risk. Report any history of inflammatory bowel disease, recurrent infections, or recent vaccination. The needle cap on some devices contains a natural rubber latex derivative; people with latex sensitivity should discuss alternatives.
What to Expect Over Time
Your response can vary. Some people notice skin changes after the starter phase, while others take longer. Sticking to your schedule is important for steady results. Keep regular check-ins with your clinician to review progress and tolerability. If your condition changes, your prescriber may adjust your plan according to the official label and your medical history.
Compare With Alternatives
Other prescription biologics for psoriasis and psoriatic arthritis include IL‑17, IL‑23, and IL‑12/23 inhibitors. IL‑17A blockade is also available as Taltz, which uses a different antibody. An IL‑12/23 option is Stelara Prefilled Syring. Your prescriber will help choose based on diagnosis, comorbidities, prior response, and injection preferences. Review condition education in our Dermatology category and during Arthritis Drugs features for context.
Pricing and Access
We provide transparent options to review the Cosentyx price after selecting your device and quantity. You can compare Cosentyx Canadian pricing with typical cash-pay rates and talk to your prescriber about suitability. US shipping from Canada is available when you place an order online with your valid prescription. Our encrypted checkout keeps your information protected during the process. If you are looking for seasonal offers, see our Promotions.
Availability and Substitutions
Supply can vary by device and package size. This biologic does not have an interchangeable generic. If a specific device is unavailable, your prescriber may recommend a suitable alternative within the same class or a different class, based on your diagnosis and treatment history. We cannot provide restock dates, but you can check back or consult your clinician about options.
Patient Suitability and Cost-Saving Tips
Good candidates are those with moderate to severe plaque psoriasis or psoriatic arthritis who have discussed risks and benefits with their prescriber. People with active serious infection or a history of severe allergy to any component should not use it. Those with inflammatory bowel disease need careful discussion about risks.
To manage out-of-pocket costs, consider:
- Multi-month fills to reduce per-order fees
- Refill reminders to avoid gaps in therapy
- Coordinating visits and lab work on a consistent schedule
- Choosing the device your clinician recommends for home use
Questions to Ask Your Clinician
- Is an IL‑17A inhibitor appropriate for my condition and history?
- Which device type do you recommend for me and why?
- What monitoring do I need before and during treatment?
- How should I handle minor infections while on this therapy?
- What are the signs that mean I should contact the clinic urgently?
Authoritative Sources
Novartis Cosentyx Product PageFDA DailyMed Prescribing InformationHealth Canada Drug Product Database
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How does this biologic work in skin and joints?
It binds to interleukin‑17A, a key signaling protein that drives inflammation in psoriasis and certain forms of arthritis. By blocking IL‑17A, it reduces the inflammatory cascade that leads to thickened plaques, redness, and joint symptoms. Because it modulates the immune response, clinicians screen for infections such as tuberculosis before initiating therapy and monitor during treatment. This targeted approach differs from broad immunosuppressants, which can affect many pathways at once.
Who should not use this treatment?
People with a serious active infection should not start it. Those with chronic or recurring infections, or a history of tuberculosis, need careful evaluation. Individuals with known severe allergy to any component must avoid it. Inflammatory bowel disease may worsen in some users, so risks and benefits should be discussed with a prescriber. Live vaccines are not recommended while receiving therapy. Your clinician will review your medical history to confirm suitability.
What are the common side effects?
Common effects include upper respiratory infections, nasal congestion, sore throat, diarrhea, headache, fatigue, and mild injection-site reactions like redness or pain. Most are transient. Serious risks include severe infections, reactivation of tuberculosis, and rare allergic reactions with swelling or hives. Inflammatory bowel disease may flare in some patients. Seek urgent medical care for symptoms such as high fever, chills, shortness of breath, or signs of a severe allergic response.
How do I store and handle the injections?
Keep the product refrigerated in its original carton and protect it from light. Do not freeze or shake. Before use, allow it to reach room temperature for the time described in the instructions. Inspect the liquid; do not use it if discolored or cloudy. Rotate injection sites and avoid damaged or infected skin. Place used pens and syringes in an approved sharps container and follow local disposal rules or pharmacy guidance.
What happens if I miss a dose?
Inject as soon as you remember, then take your next dose on your originally scheduled day. If you are unsure how to reset your schedule, contact your healthcare professional or review the official label. Do not double a dose to make up for a missed injection. Keeping a reminder system on your phone or calendar can help prevent gaps in treatment and support steady control of symptoms over time.
Can I receive vaccines during treatment?
Avoid live vaccines while using this therapy. Inactivated or non-live vaccines may be given, but their effectiveness could be reduced. Your clinician may recommend completing needed vaccinations before starting therapy and planning future vaccinations between dosing cycles. Always inform your healthcare providers that you are receiving a biologic so they can select appropriate vaccines and timing based on your individual situation.
What alternatives might my prescriber consider?
Alternatives include other biologics that target IL‑17, IL‑23, or IL‑12/23, as well as oral therapies or phototherapy depending on your diagnosis and previous response. Some options offer different dosing schedules or injection devices. Choice depends on disease type, severity, coexisting conditions, and prior treatments. Discuss goals, monitoring, and convenience with your clinician to identify the most appropriate plan for you.

