Creon Pancrelipase Capsules Online with US Shipping

What Creon Is and How It Works

Creon is a pancrelipase prescription medicine used to treat exocrine pancreatic insufficiency (EPI). It replaces missing digestive enzymes so fat, protein, and carbohydrates can be absorbed. Creon comes as delayed-release capsules that contain enteric-coated microspheres. Each capsule delivers lipase, protease, and amylase sourced from porcine pancreas. Doses are taken with meals and snacks.

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Creon is indicated for EPI due to conditions such as chronic pancreatitis, cystic fibrosis, pancreatectomy, pancreatic cancer, and other causes of pancreatic insufficiency. Strengths are expressed in units of lipase, such as 12000, 24000, and 36000 units. Capsules are not interchangeable unit-for-unit with other pancrelipase brands, so prescribers match dose and brand to clinical response.

Dosage and Usage

Creon dosing is individualized. Prescribers select a lipase unit dose based on weight, age, fat content in meals, and symptom control. A common approach is to start at a low to moderate lipase unit dose per meal and titrate to reduce steatorrhea, abdominal discomfort, and stool frequency.

• Take Creon with every meal and snack; give about half the meal dose with snacks.
• Swallow capsules whole with liquid. Do not crush or chew.
• If swallowing is difficult, open the capsule and sprinkle the enteric-coated beads on a small amount of acidic soft food (for example, applesauce). Do not crush the beads or chew. Swallow right away and drink water to clear the mouth.
• Do not mix with alkaline foods or liquids. Avoid keeping the beads in the mouth.
• Typical dosing limits: do not exceed about 2500 lipase units/kg/meal or 10000 lipase units/kg/day. Also avoid doses above 4000 lipase units per gram of dietary fat per day.

Missed dose: if a dose is missed with a meal or snack, take the next scheduled dose with the next meal or snack. Do not double the dose, and do not take Creon on an empty stomach.

Capsule strengths such as Creon 12000, Creon 24000, and Creon 36000 help reduce capsule burden. Switching strengths or brands should be guided by a prescriber.

• Storage: keep capsules dry in the original container with the desiccant at room temperature (about 20-25 C). Close the cap tightly after each use.
• Travel: carry Creon in your hand luggage, keep it dry, and avoid heat (car glove boxes, direct sun). Bring enough for the full trip and a few extra days.

Benefits and Savings

Creon helps normalize digestion by restoring pancreatic enzymes in the small intestine. Patients often see fewer bulky, oily stools, less bloating and cramping, better control of diarrhea, and improved nutrient absorption. Over time, this supports weight gain or maintenance and better levels of fat-soluble vitamins. Using a higher-strength capsule can simplify dosing by reducing the number of capsules per meal.

Ordering from YouDrugstore can lower costs by 60-80% compared with typical US prices. We ship to the US and help you access Canadian pricing on brand medications. Orders can be placed online or by phone where available, and we can send reorder reminders on request so you do not run short.

Side Effects and Safety

• Common: abdominal pain, gas, constipation, diarrhea, nausea, and oily or loose stools when the dose is not yet optimized.
• Mouth or perianal irritation if beads are chewed or retained in the mouth, or if stool is very frequent.
• Serious but uncommon: fibrosing colonopathy (risk rises with very high doses), allergic reactions (especially in those with pork protein allergy), bowel obstruction, severe abdominal pain, or hyperuricemia.

Warnings and precautions: do not crush or chew capsules or beads. High daily doses above recommended limits raise the risk of colonic strictures, especially in children with cystic fibrosis. Creon is porcine-derived; avoid if there is a known pork allergy. Use in acute pancreatitis is not advised during the acute phase. Tell healthcare providers about pregnancy or breastfeeding; pancrelipase is minimally absorbed, but clinical oversight is still needed. Drug interactions are not common, though acid suppression may affect bead release in some cases.

Onset Time

Enzymes begin working with the first meal or snack that includes Creon. Many patients notice less bloating and more formed stools within a few days as dosing is adjusted. Weight stabilization and vitamin level improvements may take several weeks. Dose optimization can require follow-up and symptom tracking.

Compare With Alternatives

Several pancrelipase brands are available. Zenpep, Pancreaze, and Pertzye are delayed-release pancrelipase products similar in concept to Creon, but they are not interchangeable unit-for-unit. Bead size, coating, and available strengths differ, so a switch should be supervised to achieve equivalent symptom control. Viokace contains non-enteric-coated pancrelipase tablets and is taken with a proton pump inhibitor to protect enzymes from gastric acid; it is usually reserved for specific situations such as post-surgical states with tailored regimens.

There is no true generic drug for Creon in North America. Prescribers sometimes switch between branded pancrelipase products to improve response or access, but brand changes should be planned with careful dose matching.

Combination Therapy

Some patients need acid suppression if symptoms persist at higher enzyme doses. A proton pump inhibitor or H2 blocker can reduce gastric acid and may improve enzyme activity in the small intestine. Fat-soluble vitamins (A, D, E, K), calcium, and vitamin B12 are often supplemented in EPI as guided by lab tests. Dietitians may suggest adjusting dietary fat, spreading calories across meals, and using nutrient-dense snacks. For diarrhea related to other causes, your clinician may consider agents discussed in educational content such as Does Metformin Cause Diarrhea or antispasmodics covered in Trimebutine Uses Dosage And Side Effects Explained when appropriate.

Patient Suitability and Cost-Saving Tips

Creon is used for EPI from conditions such as chronic pancreatitis, cystic fibrosis, pancreatic surgery, pancreatic cancer, and some rare genetic disorders. It can also support digestion in selected cases of short bowel syndrome or other malabsorption states when pancreatic output is reduced. It is not meant for pain relief in pancreatitis and is not used during acute flares.

Candidates include adults and children who have steatorrhea, weight loss, fat-soluble vitamin deficiency, and lab or clinical evidence of pancreatic enzyme deficiency. Caution is needed in those with pork allergy or a history of high-dose pancrelipase exposure with strictures. Discuss goals such as stool consistency, meal patterns, and vitamin targets with your care team.

To make therapy more affordable, prescribers often choose higher-strength capsules like Creon 24000 or Creon 36000 to reduce capsules per meal. You can order multi-month supplies when appropriate, which lowers per-month costs, and request reorder reminders so refills are timed to your usage. For condition-focused guidance, explore Exocrine Pancreatic Insufficiency or Cystic Fibrosis to learn how others manage EPI alongside enzymes.

Authoritative Sources

For detailed prescribing information, see the AbbVie CREON Prescribing Information, consult the FDA-approved label for CREON, or review the Health Canada Drug Product Database entry for Creon.

You can order Creon online from YouDrugstore at Canadian prices, and we will coordinate fulfillment through licensed partner pharmacies with prompt, express shipping to the US. If you have questions about ordering or shipping, our friendly customer-service team can help during posted office hours.

This information is educational and does not replace your provider’s advice. Use Creon only as prescribed for you, and always follow the directions on your prescription label. Seek medical help if you have severe abdominal pain, allergic symptoms, or signs of bowel obstruction.