Cresemba® Capsules and Injection for Invasive Aspergillosis and Mucormycosis

This antifungal treats invasive aspergillosis and mucormycosis in adults. It is available as oral capsules and an IV formulation. US shipping from Canada is available for eligible prescriptions, including orders paid without insurance.

What Cresemba Is and How It Works

Cresemba® contains isavuconazonium sulfate, a prodrug that converts to isavuconazole. This triazole antifungal inhibits fungal lanosterol 14α-demethylase, reducing ergosterol synthesis and disrupting the cell membrane. The treatment can be started intravenously or by mouth, then continued with one route. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Many adults begin therapy in hospital, then switch to capsules for continuation when appropriate. Capsule and IV exposures are designed to be comparable as directed by the label. For background reading on the antifungal’s role and uses, see Cresemba Uses.

Who It’s For

This medicine is indicated for adults with invasive aspergillosis or invasive mucormycosis. It is not established for pediatric patients. People with known hypersensitivity to azoles should avoid it. Those with familial short QT syndrome should not use it. Discuss liver disease, severe kidney problems, and pregnancy or breastfeeding with a clinician before starting therapy.

If you are being treated for Aspergillosis or Mucormycosis, your prescriber will decide the most suitable route and duration based on response and tolerability.

Dosage and Usage

Label-directed dosing uses a loading phase followed by maintenance. Adults typically receive loading doses given every 8 hours for the first 48 hours, then transition to once-daily maintenance thereafter. Oral capsules are swallowed whole; do not crush, open, or chew them. IV doses are infused over a defined period by trained staff.

Take doses at the same time each day when possible. Capsules may be taken with or without food. If your care team switches you between IV and oral routes, they will maintain the same total daily dosage per labeling. Always follow the official prescribing information provided with your prescription.

Strengths and Forms

Availability can vary by pack size and manufacturer packaging.

Missed Dose and Timing

If you miss a capsule dose, take it when remembered unless it is close to the next one. Do not double up doses. For IV therapy, timing is managed by healthcare professionals. Consistent daily use helps maintain therapeutic exposure.

Storage and Travel Basics

Keep capsules in their original packaging, closed tightly, and stored at room temperature away from moisture. Protect from excessive heat and humidity. Store vials per the label and facility policies. Keep all medicines out of reach of children and pets.

When traveling, carry this treatment in your hand luggage with a copy of your prescription. Use a pill organizer only if it protects from moisture and light. Do not store capsules in a car glove box. If traveling across time zones, ask your clinician for a simple plan to maintain a once-daily schedule.

Benefits

This antifungal offers oral and IV options with coordinated dosing, which can support hospital-to-home transitions. It may be started intravenously in acute settings, then continued as capsules when appropriate. For current Cresemba price, see the pricing information below.

Side Effects and Safety

• Gastrointestinal upset: nausea, vomiting, diarrhea
• Headache or dizziness: usually mild to moderate
• Low potassium or swelling: monitor as directed
• Abnormal liver tests: clinicians may order labs
• Rash or itching: report persistent skin changes
• Cough or shortness of breath: seek medical care if severe
• Infusion-related reactions with IV therapy

Serious reactions can include severe hepatic events, anaphylaxis, severe cutaneous reactions, and cardiac effects related to QT interval shortening. Seek urgent care for signs of severe allergic reactions, yellowing of skin or eyes, severe abdominal pain, or fainting. This therapy may increase hypoglycemia risk only when combined with certain agents that affect glucose; your clinician can advise.

Drug Interactions and Cautions

Isavuconazole is a substrate and moderate inhibitor of CYP3A4. Strong CYP3A4 inhibitors and strong CYP3A4 inducers are contraindicated. Use caution with sensitive CYP3A4 substrates, certain immunosuppressants, and drugs that shorten the QT interval. Alcohol can worsen dizziness or liver strain. Inform your clinician about all medicines, supplements, and herbal products you take.

What to Expect Over Time

Response is assessed clinically and with imaging or cultures when available. Many patients begin IV therapy, then switch to capsules as they stabilize. Consistent daily dosing and follow-up labs help your care team balance effectiveness and tolerability. Do not stop treatment without discussing it with your prescriber, even if you feel better.

Compare With Alternatives

Other azole antifungals used for invasive mold infections include voriconazole and posaconazole. Amphotericin B formulations are also used, particularly for mucormycosis. Choice depends on organism, site of infection, drug interactions, and tolerability. If you are comparing options, discuss potential differences in spectrum and monitoring with your clinician. For reference material on invasive infections, explore our Infectious Disease category. If you are researching budgets, check Isavuconazole price considerations in the section below.

Pricing and Access

We use transparent Canadian pricing for this therapy with prescription review. Cresemba capsules price varies by pack size and availability; see the product page for current details. For those using IV therapy, the Cresemba IV price depends on vial quantity and formulation. Ships from Canada to US for eligible prescriptions to help simplify access across borders.

Looking for seasonal deals or codes? See our Promotions. For broad infection education, you can also read Kidney Infection Care and related resources.

Availability and Substitutions

Supply can change due to manufacturer packing or wholesaler stock. If your prescribed form is unavailable, your prescriber may recommend a clinically suitable alternative. If you are tracking budgets, Isavuconazonium price will vary by route and quantity. We also carry other anti-infective products, including Humatin, within our Infectious Disease category.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults who need a mold-active azole and can be monitored for liver function and interactions. People with hereditary short QT syndrome or azole hypersensitivity are not candidates. If tablets are difficult to swallow during acute illness, supervised IV therapy may be used first.

To manage budgets, ask your clinician about multi-month prescriptions when appropriate. Ordering larger quantities can reduce per-unit costs due to fewer dispensing fees. Set refill reminders so you do not run short during ongoing therapy. For those comparing pack sizes, you can review Cresemba 186 mg price details on the product page and choose a quantity aligned with your prescriber’s directions.

Questions to Ask Your Clinician

• Route and plan: start IV, switch to capsules, or stay oral?
• Monitoring: which labs or ECG checks are recommended?
• Interactions: which medicines or supplements should I avoid?
• Adverse effects: which symptoms require urgent care?
• Duration: what milestones will guide continuation or change?
• Food and timing: best practices for daily dosing?

Authoritative Sources

• US Prescribing Information (FDA)
• Health Canada Drug Product Database
• Manufacturer Site

Ready to proceed? Order from YouDrugstore with prompt, express shipping and temperature-controlled handling when required, with US shipping from Canada for eligible prescriptions. This page is educational and not a substitute for professional medical advice.